Basic Information

Insect: Merodon equestris
Gene Symbol: ZFX
Assembly: GCA_958301585.1
Location: OY284417.1:16210029-16213076[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.003 0.65 12.1 0.2 2 23 109 131 108 131 0.96

2 20 0.0006 0.13 14.3 0.8 1 23 137 159 137 159 0.96

3 20 5.9e-05 0.013 17.4 1.0 2 23 168 189 167 189 0.98

4 20 0.00012 0.026 16.5 1.4 1 23 195 218 195 218 0.97

5 20 0.0004 0.087 14.8 2.8 1 23 250 272 250 272 0.95

6 20 1.5e-06 0.00033 22.4 1.8 1 23 278 300 278 300 0.98

7 20 8.7e-07 0.00019 23.2 2.3 1 23 306 329 306 329 0.98

8 20 0.00028 0.061 15.3 0.9 1 23 339 362 339 362 0.95

9 20 1.4e-07 3e-05 25.7 0.5 3 23 454 474 452 474 0.97

10 20 0.00017 0.036 16.0 0.3 1 23 480 502 480 502 0.95

11 20 0.0023 0.5 12.4 0.3 1 23 513 537 513 537 0.95

12 20 0.0012 0.27 13.3 1.6 1 20 543 562 543 564 0.94

13 20 0.54 1.2e+02 5.0 6.0 1 23 602 624 602 624 0.97

14 20 1e-05 0.0022 19.8 1.9 1 23 630 652 630 652 0.98

15 20 0.00022 0.047 15.7 0.2 1 23 658 680 658 680 0.97

16 20 0.00039 0.086 14.8 3.7 1 23 686 708 686 708 0.97

17 20 8.9e-08 1.9e-05 26.3 1.4 1 23 809 831 809 831 0.97

18 20 0.00031 0.068 15.2 1.5 1 23 837 859 837 859 0.99

19 20 8.1e-06 0.0018 20.2 0.4 1 23 866 888 866 888 0.99

20 20 8.2e-05 0.018 17.0 5.7 1 23 894 916 894 917 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.003	0.65	12.1	0.2	2	23	109	131	108	131	0.96
2	20	0.0006	0.13	14.3	0.8	1	23	137	159	137	159	0.96
3	20	5.9e-05	0.013	17.4	1.0	2	23	168	189	167	189	0.98
4	20	0.00012	0.026	16.5	1.4	1	23	195	218	195	218	0.97
5	20	0.0004	0.087	14.8	2.8	1	23	250	272	250	272	0.95
6	20	1.5e-06	0.00033	22.4	1.8	1	23	278	300	278	300	0.98
7	20	8.7e-07	0.00019	23.2	2.3	1	23	306	329	306	329	0.98
8	20	0.00028	0.061	15.3	0.9	1	23	339	362	339	362	0.95
9	20	1.4e-07	3e-05	25.7	0.5	3	23	454	474	452	474	0.97
10	20	0.00017	0.036	16.0	0.3	1	23	480	502	480	502	0.95
11	20	0.0023	0.5	12.4	0.3	1	23	513	537	513	537	0.95
12	20	0.0012	0.27	13.3	1.6	1	20	543	562	543	564	0.94
13	20	0.54	1.2e+02	5.0	6.0	1	23	602	624	602	624	0.97
14	20	1e-05	0.0022	19.8	1.9	1	23	630	652	630	652	0.98
15	20	0.00022	0.047	15.7	0.2	1	23	658	680	658	680	0.97
16	20	0.00039	0.086	14.8	3.7	1	23	686	708	686	708	0.97
17	20	8.9e-08	1.9e-05	26.3	1.4	1	23	809	831	809	831	0.97
18	20	0.00031	0.068	15.2	1.5	1	23	837	859	837	859	0.99
19	20	8.1e-06	0.0018	20.2	0.4	1	23	866	888	866	888	0.99
20	20	8.2e-05	0.018	17.0	5.7	1	23	894	916	894	917	0.96

Sequence Information

Coding Sequence: ATGCAAAACAATTCCGATCTATTTACCCCGATCCCGGGCGATATGACCGGCTCAAATGCACTTCTCTACAATCTGAATGATGCTGAGGAGAAGTTTTCCAAATCGAACGATTTCTACACGTTTGGAATCGATGGCTTTACAATGTCGGGCATCGACGACATGTCATCGAGTATGGCTATTCTGAGCCCTATTCCGGAGGAAACCAGTTGTTCCTTGAATGTTCCACCCTTAGAACCCCTCTTTTCACCCGTCGAGCCCGTTTCGCTCGGGCATAAGTTCGCCAATTCAGAGGGTGACTTAAAGCACAATGCGCCTAGACAAATCTCATGCGATTTATGTTCGGAAACATTTCCGTCGAATCAAGTGTTGCAGCTTCATCGAAGAGTTCAGCATATGAGAACGAAAGAGTTTCGTTGTCGCAAATGCTCCGCTTCGTTTAATTTCGAGTCGAATCTTCGATTGCATTTGGCCGCACATGTTCCCAGCTTAAACACCAAGAAGCAGTGCCCCGAGTGTAAGATGGAATTTAAGCGTCTGTCGGCGTTCAAGGGGCATCTGAGGTCGCATCAAACGAGTGATCGTTTCAAGTGTAGTCGCTGTGATAAGGAGTTCGATTTGAAGGGGTACTATGAGAAGCACATGTTGAAGGCGCATAAACCAGGCGCGGACGGAACTGTCGAGGAGATTCTCGCGAAAGTCGCAGAAAATGCAAGGTCGCGTGTGAAAAGCAAGAAATCGCAGGGGAAGTACAGCTGTCAAGAGTGTGGAAAGAATTTCTTCAAACCGTGCCTTTTGAAGCGTCACGAAGTCTCCCACACAGGTGCGAAGCCATTCCAATGTCCAGAATGTCAACATGGATTCACACAGAAAACTTCCTTGGAACGGCATATGCTACTTCATCAGGGTGTGAAGGACTACAAGTGTCCAAAATGCGACTGCAGTTTTGCGCAGAAGAACAATCTCATCGTACACATCAAACGGACACATCCTCTCCATCCCGACCTGGACAAGATGTACCCCTGCGAGTACTGTCCTTGCGTGTTTACAAAGCTCAGCAGCGTCAATCGGCACAAGGCAATGGTGCACCCCgataaaaacaatgaaaccGATGACTTGCtcattgatgatgacgatggaaaCGTGACGGCAGCTAGAGTCATGGAACAGCTGAAGAGTTTTCAAGAGTCAATGAGTATCATGGATATGCAGCCCCCTGCGCTCGAACTTTCTCTATTGAAGCCACCGTCCCCGGGACCTCAGGTTCGCACCGTGGACATCGTGGACACATTAAACCCGGCGAGAGAAAAGACCTACAAGACTGTCAAGGAGGTCATATACAAGGGAGAGAGGACATTGGCTTGTCCTTACTGCGATAAACCCTTCAAGAAGCAATTCGATCTATTAAGACACATACGTACGCATACCAAGGAACGTTTATTCGATTGTGGGGTTTGTCACAAAAACTTCGCAACACGAGCCGCTCTCAGGGTCCATGAATCCATTCACCTGTCCAACCAAGAGAAACCGGCGAAACTCTTCGTCTGCGTCGAAGAGGAGTGTGGTAAGCGGTTCGCGTCTATGCGGAAACTGGATCTCCACACAAAGACTCATTCCAATTCGATTTCATACATCTGTCCACTGTGCTCGAAGACCTTCACATCGAAGGCAGGCTTCTCTGCCCACAAGCATCACCAGAAAGATAAGGAATTCGAAATGTTGCGGCCGCTTCTCATGCCTCCAGTGAGACTCAACACAGACGACCTTGAGGAAGCCGAGAAAATCGAAGAATACACCAAAAGGAAACATCAATGCTGCATATGCGGACAGAAAATGCAGAAACTCTCACACCTGCGGCAGCACGAAGCCACGCATACCGGCGAGAAACCATTCAACTGCTCTGTCTGCTTCAGATCATACACAACCCAGAGTTCCCTCAACCAGCACCTTAAGATCCACACGGCAGATAAGCAATTCATGTGCGCCATATGCAATGCCAAGTTCTTAACGCCTTCGCTATTGAAAAGGCACATGATATCCCACACCGACGATCGCAAGTTCGCCTGCCCATACTGTAACGAGCACTTCAAAACCAGCGACAATTGCAAAAACCACATTCTGATCCACGCTCGTCACCTACTCTCCACTGCCGAATCACCCTTACACGATGATCAGGACTACGAACCACTGCCAGTGGAGGAACCTCCTTCGACACCTCCTCCCGAAGACTACTCCCAGCCATGCATCGCGGTTGTACAGGACCCGCAGAAATATGTCGCGCCCAAGTTCATCCAACTGGAGATGGTGAAAAATTGCAAGAAACACAATCACAAAAACCTTACCATAGAAACGGTGTCCAACTCGCCGAAGAAAAAGTCCGCCAAGCAGTCCATAGCACGATCACTCAAACAGATCAACCAAACTGGCCATCCATGCAGTGAGTGTGGCAAGACCTTCTACAAACCAAGCGATCTGCAACGGCATGCGAGGACACATACGAAGGAGAAACCCTTTCGATGCGAATTGTGTTCGAAAACGTTTGCGTTGATGTCCACATTGGTGCAGCATAAGAAGACGCACGATACTAAGCGGGAGACGTACACGTGTCAGGTGTGCGGGAAGAAGTACACCTCGCAGAAGGTCCTGGTTGTGCATTTGAGGATCCATACCGGCGAACGGCCGTTCCAATGTAACGTGTGCAAGAAGACGTTTCGAACGTCGGGTCATAAGATATCCCACATGAAAGCCCATCATAAAAAGAGAAGACAGTAG
Protein Sequence: MQNNSDLFTPIPGDMTGSNALLYNLNDAEEKFSKSNDFYTFGIDGFTMSGIDDMSSSMAILSPIPEETSCSLNVPPLEPLFSPVEPVSLGHKFANSEGDLKHNAPRQISCDLCSETFPSNQVLQLHRRVQHMRTKEFRCRKCSASFNFESNLRLHLAAHVPSLNTKKQCPECKMEFKRLSAFKGHLRSHQTSDRFKCSRCDKEFDLKGYYEKHMLKAHKPGADGTVEEILAKVAENARSRVKSKKSQGKYSCQECGKNFFKPCLLKRHEVSHTGAKPFQCPECQHGFTQKTSLERHMLLHQGVKDYKCPKCDCSFAQKNNLIVHIKRTHPLHPDLDKMYPCEYCPCVFTKLSSVNRHKAMVHPDKNNETDDLLIDDDDGNVTAARVMEQLKSFQESMSIMDMQPPALELSLLKPPSPGPQVRTVDIVDTLNPAREKTYKTVKEVIYKGERTLACPYCDKPFKKQFDLLRHIRTHTKERLFDCGVCHKNFATRAALRVHESIHLSNQEKPAKLFVCVEEECGKRFASMRKLDLHTKTHSNSISYICPLCSKTFTSKAGFSAHKHHQKDKEFEMLRPLLMPPVRLNTDDLEEAEKIEEYTKRKHQCCICGQKMQKLSHLRQHEATHTGEKPFNCSVCFRSYTTQSSLNQHLKIHTADKQFMCAICNAKFLTPSLLKRHMISHTDDRKFACPYCNEHFKTSDNCKNHILIHARHLLSTAESPLHDDQDYEPLPVEEPPSTPPPEDYSQPCIAVVQDPQKYVAPKFIQLEMVKNCKKHNHKNLTIETVSNSPKKKSAKQSIARSLKQINQTGHPCSECGKTFYKPSDLQRHARTHTKEKPFRCELCSKTFALMSTLVQHKKTHDTKRETYTCQVCGKKYTSQKVLVVHLRIHTGERPFQCNVCKKTFRTSGHKISHMKAHHKKRRQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00688863;
90% Identity: -
80% Identity: -