Basic Information

Insect: Eumerus sabulonum
Gene Symbol: ZFX
Assembly: GCA_951905685.1
Location: OX645064.1:95692443-95695501[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.003 0.53 12.0 0.2 2 23 108 130 107 130 0.96

2 20 0.00056 0.098 14.3 0.8 1 23 136 158 136 158 0.96

3 20 0.00013 0.023 16.3 1.1 2 23 167 188 166 188 0.98

4 20 0.00075 0.13 13.8 1.2 1 23 194 217 194 217 0.96

5 20 0.0023 0.4 12.3 2.9 1 23 249 271 249 271 0.95

6 20 7.2e-05 0.013 17.1 2.2 1 23 277 299 277 299 0.98

7 20 8e-07 0.00014 23.2 2.3 1 23 305 328 305 328 0.98

8 20 0.0064 1.1 10.9 1.0 1 23 338 361 338 361 0.95

9 20 5e-08 8.8e-06 27.0 0.8 3 23 453 473 451 473 0.97

10 20 1.2e-05 0.0022 19.5 0.1 1 23 479 501 479 501 0.97

11 20 0.0013 0.23 13.1 0.5 1 23 512 536 512 536 0.94

12 20 0.0012 0.2 13.3 1.6 1 20 542 561 542 563 0.94

13 20 0.5 88 5.0 6.0 1 23 601 623 601 623 0.97

14 20 2.9e-06 0.00052 21.4 2.1 1 23 629 651 629 651 0.98

15 20 0.00081 0.14 13.8 0.9 1 23 657 679 657 679 0.98

16 20 0.001 0.18 13.4 4.0 1 23 685 707 685 707 0.97

17 20 8.7e-07 0.00015 23.1 0.9 3 23 810 830 809 830 0.99

18 20 0.0012 0.22 13.2 1.4 1 23 836 858 836 858 0.99

19 20 7.5e-06 0.0013 20.2 0.4 1 23 865 887 865 887 0.99

20 20 7.6e-05 0.013 17.0 5.7 1 23 893 915 893 916 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.003	0.53	12.0	0.2	2	23	108	130	107	130	0.96
2	20	0.00056	0.098	14.3	0.8	1	23	136	158	136	158	0.96
3	20	0.00013	0.023	16.3	1.1	2	23	167	188	166	188	0.98
4	20	0.00075	0.13	13.8	1.2	1	23	194	217	194	217	0.96
5	20	0.0023	0.4	12.3	2.9	1	23	249	271	249	271	0.95
6	20	7.2e-05	0.013	17.1	2.2	1	23	277	299	277	299	0.98
7	20	8e-07	0.00014	23.2	2.3	1	23	305	328	305	328	0.98
8	20	0.0064	1.1	10.9	1.0	1	23	338	361	338	361	0.95
9	20	5e-08	8.8e-06	27.0	0.8	3	23	453	473	451	473	0.97
10	20	1.2e-05	0.0022	19.5	0.1	1	23	479	501	479	501	0.97
11	20	0.0013	0.23	13.1	0.5	1	23	512	536	512	536	0.94
12	20	0.0012	0.2	13.3	1.6	1	20	542	561	542	563	0.94
13	20	0.5	88	5.0	6.0	1	23	601	623	601	623	0.97
14	20	2.9e-06	0.00052	21.4	2.1	1	23	629	651	629	651	0.98
15	20	0.00081	0.14	13.8	0.9	1	23	657	679	657	679	0.98
16	20	0.001	0.18	13.4	4.0	1	23	685	707	685	707	0.97
17	20	8.7e-07	0.00015	23.1	0.9	3	23	810	830	809	830	0.99
18	20	0.0012	0.22	13.2	1.4	1	23	836	858	836	858	0.99
19	20	7.5e-06	0.0013	20.2	0.4	1	23	865	887	865	887	0.99
20	20	7.6e-05	0.013	17.0	5.7	1	23	893	915	893	916	0.96

Sequence Information

Coding Sequence: ATGCAAAACAATTCGGATCTATTCAACCCCATCCCCGGTGATATGACTACATCCGATGCGCGCCTCTACCACCTGAACGATGACGAAGAAAAGTTATCCAAATCGAACGATTTCTACCCATTCGGAATCGATGGCTTCACCATGTCAGGAATCGATGATATCTCAAGTATGGTGATCCTCAGTCCGATACCAGAGGAAACAAGTTGTTCGTTAAATGTATCACCTCTGGAGCCGCTTTTTTCACCGGTCGATTCCGTCCCGTCCGGGCACAAATTCACCAATTCGGAAATCGACAGTAAACCCACCGCGGTCAGGCAAGTCTCGTGCGATTTGTGTTCGGAGACATTCCCGTCGAACCAAGTGTTGCAACTGCACCGGAGGGTACAGCATATCCGAGCGAAAGAGTTTCGTTGTCGCAAGTGTTCCGCTTCGTTCAATTTTGAGTCGAATCTTCGACTGCATTTGGCGGCACATGTGCCCAGTTTGAGCGTCAAGAAACAGTGCCCGGAATGTAAAATGGAATTCAAGCGATTGTCGGCATTCAAGGGGCATCTGAAGTCGCATCAGTCGAGTGATCGTTTTAAGTGCAATCGCTGCGACAAGGAGTTCGAGCTCAAGGGCTACTACGAGAAACATACGGCAAAGGCGCATAAACCAGGCGCCGACGGTACTATCGAAGAGATTCTCGCCAAAGtcGCAACAAACGCTAGATATCGAGTGAAGGACAAGAAATCGCAAGGGAAATACACCTGCCAAGCGTGTGGGAAGCGATTTTTCAAACCGTGCCTGTTGAAACGCCACGAAGTGTCCCATACGGGGGCGAAACCATTCCAATGTGCAGAGTGCAAGCACGGATTCACACAGAAAACCTCGCTGGACAGGCATATGCTGCTGCATCAGGGCGTTAAAGATTACAAATGTCCCAAATGCGACTGTAGTTTCGCCCAGAAAAACAATCTCATCGTCCACATCAAACGGACGCATCCTCTCCATCCGGACTTGGACCAGATGTATGCGTGTGAGTACTGTCCGTGCATATTCACCAAACTGAACAGCGTCAATCGGCACAAGGCAATGGTGCACGCGAATAGGGACAATGCCACTGATAACCCATTTGTCGACGATGACGATGGCAACGTGAATGCTGCCAAGGTCATGGAGCAACTAAAGAGTTTCCAGGAATCGATGAGCATCATGGACATGCAACCGTCAGCACTCGAACTCTCCCTATTAAAGCCACCATCGCCTGGGCCTCAGGTTCGCACGGTCGAGATCGTGGACACGCTAAACCCGAAGAGAGAAAAGACCTACAAAACTGTTAAGGAGATCGTATATCGGGGGGAGAGGACGTTAGCGTGTCCGTACTGTGATAAATCGTTCAAGAAGCAATTCGATCTGTTAAGGCACATCCGTACTCATACCAAGGAAAGGCTATTCGAGTGCGAGGTTTGCCAGAAAAACTTCTCCACGCAAGCTGCTCTCAGGGTACATGAATCTATCCACTTGTCCAGCCAAGAAAAGCCCGCAAAATTGTTCGTCTGCGTTGAGGATCAGTGTGGCAAGCGATTCTCGTCCATTCGGAAGCTGGACATTCACACGAAGACACACAGCAACTCAATTTCATATATCTGCCCTCTGTGCTCGAAGACGTTTACCTCCAAGGCAGGTTTTTCGGCCCACAAACACCATCAAAAGGACAAGGAATTTGACATGCTTCGTCCGCTTCTCATGCCGCCGGTCAAACTCAACACAGACGACATCGAAGAAGCCGAGAAAATTGAGGAGTATGCCAAGAGAAAACATCAATGCTGCATATGCGGCCAGAAAATGCAAAAACTCTCGCACCTGCGGCAACACGAAGCCACCCATACGGGTGAGAAACCATTCAAATGCTCCATCTGCTTCAGATCATATACGACTCAGAGTTCCCTCAATCAGCACGTCAAGATCCACACCGCAGACAAGCAGTTCACGTGCACCGTATGCAACGCCAAATTCCTTACGCAGTCTCTGGTCAAGCGGCACATGATCTCGCACAGTGATGAGCGCAAATTCGCCTGTCCCTACTGCAGCGAGCACTTTAAAACCAACGACAATTGCAAGGACCACATCCTAACGCACGCTCGTAACCTTCTCTCCGCCACCGAACTGCACTTCGGAGACGAGCAAGACTGCCAAGAGCAACATTTTCAGGAACCTCTTCAGCTCGCTGCTCCCGAAGACTATACACAATCCTGCATAGCCGTCGTACAAGAGCAACAACCGCACAACACACCGAAATTCATCGAACTGGAGCTGATAAAAAACTGCAAGAAGCACAATCACAAGAATCTAACCATCGAAACGTTGCCCAGTGTGGCGAAGAAAAAATCCGCCAAACAGTCCATCGCACGATCGTTGAAACAAATCAATcaaaccggacatggctgcagTGAGTGTGGCAAAACCTTCTACAAAGCCAGTGACTTGCAGCGACATTCGAGAACCCACACGAAAGAGAAACCTTTCCGGTGTGAATTGTGCTCGAAACAGTTTGCCCTGATGTCTACTTTGGTGCAACACAAGAAGACACACGACACGAAACGTGAGACCTATACTTGTCAGGTATGCGGTAAGAAGTACACGTCGCAAAAGGTTCTGGTCGTGCACTTGAGAATCCATACGGGCGAACGACCGTTTCAGTGTAATGTGTGCAAAAAGACGTTTAGAACGTCCGGCCATAAGATATCCCACATGAAAGCGCATCATAAAAAGAAAAGGCAATGA
Protein Sequence: MQNNSDLFNPIPGDMTTSDARLYHLNDDEEKLSKSNDFYPFGIDGFTMSGIDDISSMVILSPIPEETSCSLNVSPLEPLFSPVDSVPSGHKFTNSEIDSKPTAVRQVSCDLCSETFPSNQVLQLHRRVQHIRAKEFRCRKCSASFNFESNLRLHLAAHVPSLSVKKQCPECKMEFKRLSAFKGHLKSHQSSDRFKCNRCDKEFELKGYYEKHTAKAHKPGADGTIEEILAKVATNARYRVKDKKSQGKYTCQACGKRFFKPCLLKRHEVSHTGAKPFQCAECKHGFTQKTSLDRHMLLHQGVKDYKCPKCDCSFAQKNNLIVHIKRTHPLHPDLDQMYACEYCPCIFTKLNSVNRHKAMVHANRDNATDNPFVDDDDGNVNAAKVMEQLKSFQESMSIMDMQPSALELSLLKPPSPGPQVRTVEIVDTLNPKREKTYKTVKEIVYRGERTLACPYCDKSFKKQFDLLRHIRTHTKERLFECEVCQKNFSTQAALRVHESIHLSSQEKPAKLFVCVEDQCGKRFSSIRKLDIHTKTHSNSISYICPLCSKTFTSKAGFSAHKHHQKDKEFDMLRPLLMPPVKLNTDDIEEAEKIEEYAKRKHQCCICGQKMQKLSHLRQHEATHTGEKPFKCSICFRSYTTQSSLNQHVKIHTADKQFTCTVCNAKFLTQSLVKRHMISHSDERKFACPYCSEHFKTNDNCKDHILTHARNLLSATELHFGDEQDCQEQHFQEPLQLAAPEDYTQSCIAVVQEQQPHNTPKFIELELIKNCKKHNHKNLTIETLPSVAKKKSAKQSIARSLKQINQTGHGCSECGKTFYKASDLQRHSRTHTKEKPFRCELCSKQFALMSTLVQHKKTHDTKRETYTCQVCGKKYTSQKVLVVHLRIHTGERPFQCNVCKKTFRTSGHKISHMKAHHKKKRQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00991991;
90% Identity: -
80% Identity: -