Mmel034956.2
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000289.1:573011-575170[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 21 0.00083 0.096 16.6 0.7 1 23 19 42 19 42 0.96 2 21 0.2 23 9.1 4.4 1 23 107 130 107 130 0.98 3 21 0.0034 0.4 14.7 4.8 1 23 136 159 136 159 0.98 4 21 0.016 1.9 12.5 0.6 1 23 165 188 165 188 0.96 5 21 0.00064 0.075 17.0 2.5 1 23 194 217 194 217 0.98 6 21 0.0026 0.3 15.1 1.0 1 23 223 246 223 246 0.96 7 21 0.021 2.5 12.2 1.6 1 23 252 275 252 275 0.96 8 21 0.76 88 7.3 3.5 1 23 281 304 281 304 0.95 9 21 0.0023 0.27 15.2 1.7 1 23 335 358 335 358 0.96 10 21 0.03 3.4 11.7 1.1 1 23 364 387 364 387 0.95 11 21 0.014 1.6 12.7 3.9 1 23 393 416 393 416 0.96 12 21 1.2 1.4e+02 6.6 3.6 1 23 422 445 422 445 0.95 13 21 0.069 8.1 10.6 0.5 1 23 451 474 451 474 0.96 14 21 1.8 2.1e+02 6.1 1.6 1 23 480 503 480 503 0.95 15 21 0.0015 0.17 15.8 2.2 1 23 509 532 509 532 0.96 16 21 0.62 72 7.6 3.5 1 23 537 560 537 560 0.95 17 21 0.0023 0.26 15.2 2.7 1 23 566 589 566 589 0.96 18 21 0.0001 0.012 19.5 0.7 1 23 595 618 595 618 0.98 19 21 0.12 14 9.8 3.1 1 23 624 647 624 647 0.96 20 21 0.027 3.2 11.8 1.6 1 23 653 676 653 676 0.96 21 21 0.00042 0.049 17.5 2.2 1 23 682 705 682 705 0.98
Sequence Information
- Coding Sequence
- ATGTACATCACCGATTTCAGGAACCACACTAACGAGCATTACAAGGTGAAAATGTACAAATGTGGAATTTGTGACAAAAGGTACAAGGCCAAGCAATCTCTCAAGCTACATGTAGAAAAAATCCATGCAGATAATGAAGGAAGAGATGTTCAAAAATACTTTGGGTGTGACTATTTCAAAGCAAACGTTAAAAATATAAAAGAGAGATCTACGCACTCGCATAATGGTGAAAAACAATGTCAGTACACGAAATGCAAATTTGAAGCAAGGATCAAATGTCACCCAAAATCACAAATAAAACATCTAAAGACAGGCAAATATAAGTGCGCGAATTGCGAATTTAACACTAATTACAGGTGTTATTTAGAAAGGCACATGAAAATAAAACATCCAATGGAAAATAGTTATAAATGCAAGGAGTGTGAATTCAAGACGAAAAACAAATACTATTTAAAATCACACGTGAAAACGAAGCATCTTGGAAAAAGAATTTATAAATGCGCAGAGTGTAAATACGGAACAAATTCCACGTCAGACTTAGACAAACACATAAAAGCAAAACATCTGAAACAAAACTATTATAAATGCACGGAGTGTGAATTCAAGACGAATTACAAGTCAAGTTTACAAGTGCACATTAAAACAAAACATCTGGAACAAAATAATTTTAAATGCGCAGAGTGTGAATACAAGACAAATTACAAGTCAAGTTTGCAAGTACACATAAAGGCCAAGCATCTTAAAGAATATGATTATAAATGCGCAGAGTGTGAATTCAAGACAAACTACAAGTCAAGTTTCGAAGACCACATGAAAGCAAAACATCTTAAAGAAAATAATTATCAATGCACAGAGTGTGAATTCAAGACAAACTGCAAGTCAAGTTTAGAAAGACACGTAAAAGCAAAACACCTTGAAGAAAATGATTATAAATGCGCTGAGTGTGAATTCAAGTCAAATTTGGAAGAACACATAAAAGCAAGACATCTGAAACAAAATGATTATAAATGCATGGAGTGTGGATACAAGACAAACATCAAGTCATACCTAAGGAAACACATAAAAGCAAAACATCTTAAAGAAAATAATTATCAATGCATGGAGTGTGAATACAAGTCAAACATTAAGTCAAATTTAAAAAATCATGTCAAAGCGAAACATCTGAACCAAAAGGATTATAAATGCACGGAGTGTGAGTACAAGACATATTATAAATCACACTTGGGGAAACACATAAAAGCAAAACATTTGAATCGAAAGGATTATAAATGCGCAGAGTGTGAATTCAAGACAAACTACAAGACATGTTTAAAGGAGCACGTCAAAGCAAAACATCTCAATCAAAAGGATTATAAATGCGCAGGGTGTGAATTCAAGACGAATTACAAGTCAACTTTAGAAGGACACATACAGGGGAAACATCTGAATCAAAGGAATTATAAATGCGTAGAGTGTGAATTCAAGACAAGCTACAAGAAATATATAACAGAACACGTAAAAGCGAAACATCTTAAAGAAAATAATTATCAATGCACAGAGTGTGAATACAGGACAAACATGAAGTCATATTTAAAAAAGCACATAAAAGCAAAACATCTGAAACATGATTATAAATGCACAGAGTGTGAATACAAGGCAAACTACAAGACATGTTTAAAGGAGCACGTCAAAGCAAAACATCTCAATCAAAAGGATTATAAATGCACAGAGTGTGAATTCAAGACAAACTACAAGTCGTATTTAAAAGTACACATGAAAGCTAAACATCTGAAACAAAAGGATTATAAATGCACAGAGTGTGAATACATGGCAAATCGCAAGTCAAATTTACAAGTGCACATAGAAACAAAGCATCTAAAACAAAAGGGTTATGAATGCACACAGTGCGAATTCAAAACAAACTACAAGTCATGTTTAGAGGAACACATAAAAGCAAAACACCTGAAGCAAAATGATTATAAATGCGCAGAGTGCGAATTCAAGACAAACATCAAGTCATATTTAAAGAAACACATAAAAGCGAAACATCTTAAAGAAAGTGATTACAAATGCATGGAGTGTGAATATAAGACAAACTACAAGTCAAGTTTAGAGAGACACATGAAAATAAAACATCTTAAAGAAAGCGTGGAGTATGAATTCAAGACAAGTCCTATTTAA
- Protein Sequence
- MYITDFRNHTNEHYKVKMYKCGICDKRYKAKQSLKLHVEKIHADNEGRDVQKYFGCDYFKANVKNIKERSTHSHNGEKQCQYTKCKFEARIKCHPKSQIKHLKTGKYKCANCEFNTNYRCYLERHMKIKHPMENSYKCKECEFKTKNKYYLKSHVKTKHLGKRIYKCAECKYGTNSTSDLDKHIKAKHLKQNYYKCTECEFKTNYKSSLQVHIKTKHLEQNNFKCAECEYKTNYKSSLQVHIKAKHLKEYDYKCAECEFKTNYKSSFEDHMKAKHLKENNYQCTECEFKTNCKSSLERHVKAKHLEENDYKCAECEFKSNLEEHIKARHLKQNDYKCMECGYKTNIKSYLRKHIKAKHLKENNYQCMECEYKSNIKSNLKNHVKAKHLNQKDYKCTECEYKTYYKSHLGKHIKAKHLNRKDYKCAECEFKTNYKTCLKEHVKAKHLNQKDYKCAGCEFKTNYKSTLEGHIQGKHLNQRNYKCVECEFKTSYKKYITEHVKAKHLKENNYQCTECEYRTNMKSYLKKHIKAKHLKHDYKCTECEYKANYKTCLKEHVKAKHLNQKDYKCTECEFKTNYKSYLKVHMKAKHLKQKDYKCTECEYMANRKSNLQVHIETKHLKQKGYECTQCEFKTNYKSCLEEHIKAKHLKQNDYKCAECEFKTNIKSYLKKHIKAKHLKESDYKCMECEYKTNYKSSLERHMKIKHLKESVEYEFKTSPI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00990366;
- 90% Identity
- -
- 80% Identity
- -