Mmel064055.1
Basic Information
- Insect
- Melolontha melolontha
- Gene Symbol
- -
- Assembly
- GCA_935421255.1
- Location
- CAKXYX010000534.1:369200-371103[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.0036 0.41 14.6 3.8 1 23 30 53 30 53 0.96 2 19 0.13 16 9.7 6.9 1 23 91 114 91 114 0.95 3 19 0.13 15 9.7 3.8 1 23 120 143 120 143 0.98 4 19 2 2.3e+02 6.0 0.7 10 23 154 168 152 168 0.91 5 19 5.6e-06 0.00065 23.4 0.8 1 23 174 197 174 197 0.96 6 19 0.0052 0.61 14.1 3.4 1 23 203 226 203 226 0.98 7 19 3.7e-05 0.0043 20.9 1.4 1 23 232 255 232 255 0.98 8 19 0.0041 0.48 14.4 3.9 1 23 261 284 261 284 0.98 9 19 2e-05 0.0024 21.7 2.1 1 23 290 313 290 313 0.98 10 19 0.0024 0.29 15.1 0.5 1 23 319 342 319 342 0.97 11 19 0.00018 0.022 18.7 1.5 1 23 348 371 348 371 0.98 12 19 0.00058 0.068 17.1 1.5 1 23 377 400 377 400 0.98 13 19 3.6e-05 0.0042 20.9 3.0 1 23 406 429 406 429 0.98 14 19 0.00019 0.023 18.6 1.8 1 23 435 457 435 457 0.99 15 19 2.4 2.8e+02 5.7 0.1 10 23 464 478 461 478 0.87 16 19 0.033 3.9 11.6 0.9 1 23 484 507 484 507 0.97 17 19 4.4e-05 0.0052 20.6 1.9 1 23 513 536 513 536 0.98 18 19 0.0012 0.14 16.1 1.8 1 23 542 565 542 565 0.96 19 19 0.00017 0.02 18.8 3.3 1 23 571 594 571 594 0.98
Sequence Information
- Coding Sequence
- ATGTACAAATGTACACAATGCAAGTTCAGAACAAAATACCATGTCGACTTCAGGCACCATTCCAATGAACATTACCATGTGAAAATGTACAAATGTAGAATTTGTCACAGGAGATACAATACGAACATATCTCTCAAGACGCACGTGGAAAAAACTCATGTTGATAATGCAAGAAGAAATGTCCAGGAATACTCTTTGTGTGATTATTTCAAAACTAATATTAAACATATACAAGAGGGATCTACACATTCAGAAGGCGGTGAAAAACAATATTTATGCCCGAAATGTAAATTTCAAACAAGGAACAAATGTCACTTAAAATCACATATAAAAGTCAAACATCTGAGGAGACGCAAATATAAATGCGCAAATTGCGAGTTTAAGACATATTACAGGACCTATTTAAAAATGCACATGAAAATGAAACATCTCATGGAAAATGATTATAACTGCTTCAAGACAAAGAACAAATCAAATTTAAACGCACACGTAAAAAGAAAACATCTCAAAGTAACCGATTATAAATGCCCAGACTGTGAATACAAAACAAATGACAAGTCAAATTTAAAAAAACACATAAAGGGCATACATTTTAAACAACACGATTATAAATGTTCAGAGTGTGAATACAAGACATATCATACGCCAACTTTAAAAAGACACATAAAGACAATTCATTTTAAAGAACATGATTATAAATGCGAAGAGTGTGAATATAAGACAAATGACAAGACAAATTTAAAAAATCACATAAAGACAATACATCTTAAAGTAAGCGATTATAAATGCACAAGCTGTGAATACAAGACAAATTACAAGACAAGTTTAAAGAAGCACATAAAGACAATGCATCTTAAAGAACACGATTATAAATGCACAGAGTGTGAATACAAGACAAATGACAAAACAAATTTAAAAAGACACATAAAGACAATACATTTTAAACAACACGGTTATAATTGTGTAGAGTGTGAATATAAGACAAATGAAAAGGCAAATTTAAAAACACACATCAAGACAATACATCTTAAAGTATGCGATTACAAGTGTACAGAGTGTGAATACAAGACAAATTACAAGATAAATTTAGAAAAACACATAAAGACAATACATCTTAAAGTAAGCGATTATAAGTGTGCAGAGTGTGAATACAAGACAAATCACTCAGCAGCTCTAAAAAGACACATCAAGAGAATACATTTTAAAGAACAGGATTATAAATGCGACGAGTGTGAATATAAGACAAATGACAAGTCACATTTAAAAAACCACATAAAGACAATACATCTTAAAGTAAGCGATTATAAGTGCGCAGAGTGTGAATACAAGACCAATTACAAGTCAAATTTGAAAAACCACTTAAAAATACATCTTAAATATGAATACAAGACAAATGACAGGCAAAATTTAAAAAGACACATAGAGACAGTACATCTTAAAGCTTGCGATTATAAATGCATAATCTGTGAATACAAGGCAAATTACAAGACGAATTTAAGTAGACACATAAAGACAGTACATCTTAAAGAAAATGATTTTAAATGCACAGAATGTGAATACAAGACAAGTGACGAACAATATTTAAAAAGACACATGAGGACAATACATCTTAAAGAACGTGATTTTAAATGCACAGAGTGTGAATACAAGATAAATAACAAGCCGCATTTAAAAAGACACATAAAGGCAATACATCTTAAAGAACATGATTATAAATGCGAAGAGTGTGAATACAAGACAAACGACAAATCACATTTAGAAAGACACACGAAGAGAATACACCTTAAAGAATACGATTATAAATGA
- Protein Sequence
- MYKCTQCKFRTKYHVDFRHHSNEHYHVKMYKCRICHRRYNTNISLKTHVEKTHVDNARRNVQEYSLCDYFKTNIKHIQEGSTHSEGGEKQYLCPKCKFQTRNKCHLKSHIKVKHLRRRKYKCANCEFKTYYRTYLKMHMKMKHLMENDYNCFKTKNKSNLNAHVKRKHLKVTDYKCPDCEYKTNDKSNLKKHIKGIHFKQHDYKCSECEYKTYHTPTLKRHIKTIHFKEHDYKCEECEYKTNDKTNLKNHIKTIHLKVSDYKCTSCEYKTNYKTSLKKHIKTMHLKEHDYKCTECEYKTNDKTNLKRHIKTIHFKQHGYNCVECEYKTNEKANLKTHIKTIHLKVCDYKCTECEYKTNYKINLEKHIKTIHLKVSDYKCAECEYKTNHSAALKRHIKRIHFKEQDYKCDECEYKTNDKSHLKNHIKTIHLKVSDYKCAECEYKTNYKSNLKNHLKIHLKYEYKTNDRQNLKRHIETVHLKACDYKCIICEYKANYKTNLSRHIKTVHLKENDFKCTECEYKTSDEQYLKRHMRTIHLKERDFKCTECEYKINNKPHLKRHIKAIHLKEHDYKCEECEYKTNDKSHLERHTKRIHLKEYDYK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00989830; iTF_00989920;
- 90% Identity
- -
- 80% Identity
- -