Math035715.1
Basic Information
- Insect
- Mellicta athalia
- Gene Symbol
- -
- Assembly
- GCA_905220545.1
- Location
- HG992200.1:9671100-9673595[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 1.9 2.3e+02 3.9 6.5 1 23 28 50 28 50 0.98 2 18 1.2 1.5e+02 4.5 0.5 2 23 78 100 77 100 0.95 3 18 0.0005 0.062 15.1 1.1 1 23 123 145 123 145 0.98 4 18 3.2 3.9e+02 3.2 0.5 2 23 150 171 149 171 0.82 5 18 4.8e-05 0.0059 18.3 0.8 1 19 176 194 176 199 0.96 6 18 0.16 20 7.2 4.7 2 23 209 231 208 231 0.95 7 18 0.0071 0.87 11.5 3.0 1 23 237 260 237 260 0.96 8 18 0.0003 0.037 15.8 2.7 1 23 264 286 264 286 0.98 9 18 3.2 3.9e+02 3.2 0.5 1 10 331 340 331 349 0.77 10 18 0.0058 0.71 11.8 0.1 2 23 381 403 380 403 0.95 11 18 0.00015 0.018 16.8 4.1 1 23 427 449 427 449 0.98 12 18 0.095 12 8.0 1.2 2 23 454 475 454 475 0.96 13 18 0.00055 0.068 15.0 1.1 1 22 480 501 480 503 0.89 14 18 3.2 3.9e+02 3.1 4.3 2 23 513 535 513 535 0.95 15 18 0.00035 0.043 15.6 2.4 1 23 541 564 541 564 0.94 16 18 2.3e-06 0.00029 22.5 1.4 2 23 569 590 568 590 0.96 17 18 7.3e-05 0.0089 17.8 4.0 1 23 596 618 596 618 0.98 18 18 8e-05 0.0098 17.6 1.6 1 23 624 647 624 647 0.97
Sequence Information
- Coding Sequence
- ATGACAATACTAGAGCGGTATAACGCAGCCAAATTTATATCGTACACAACAGTAAGACCATTTAAGTTCATGGGCTCAAGTTTTAAATGCTTTTTCTGTACTCATTACTTTTCGGAAATTAATCATTTACTAGAACATACTTCGACACACGAAGTTATAGACGAAGAGATAATTTTAGAAAAGTATGTACCTAAAGGGAAAAGAACGTTACAAGTGGATATTTCAAAATTACAATGTCGGCTGTGTGACCAACCTTATCTGAATTTAAACAAGATACGTAATCATTTAAAAACAGAACATCAGAAGGAATTCGCGCCGGTCGGTAATGGCATGACAGAATACATTATGGAGGCTCAAAATGGTTCATTTATATGTCACATGTGCGACATGAGCTTCCCTTCGTTCCCGCTCTATAACTCTCATATAAATAGCCACGTTGGCAAAGTTGTCTGCGATTTTTGCGGAGTTGGATTCCTAAATCAGCACATCTTAAGGACACACAAGGCATCGCATGTAACTAAAGACTTCCGTTGCAAGGAATGCGATCGAGTTTTCGTCAAAAAGTCCCAATTGAAATATCACGATGATATTGTTCACAAAGGAAAAGACAGAGTTAGGCTAAAGAAATGTCACCTCTGTCCGCAAACGTTTAAGGAGCATTATAGTAAAATGGTGCACCTTAAGCAAGTTCACGGAATAGTAAAGAGTTTCTCGTGTCACGTGTGTAAATCGGTTTACAGCACGCGACGCGCTCTGACCGAACACACGACCAAGAGTCACACCGAGAAGTACAAATGTAAAGTGTGCTCTAAATGCTTTGGGATAGAGTCTAAATTGAAACTGCATTTGCGTGGACACACCGTGGCGCCTCCTAGAGTTCTTCCCACAAGTAGTAAATGGTCCATGACGCTGGCTGAGAGAATAAACGCGgcgtatatattaaaaaatacgaCTGTGACTCCATTCACATATTTGTTGTTTCCTAGCTcctataaatgtttgtattgtgacgaaaaatatttagaaattcaTATTTTACTAGAACATTCTAGAAATCACGTAGTTCCTAGCCACGATAAAATTCTAAAAGACATATTAAAGAAaggcaagaaaaaaattaaagttgaCATTTCGAATCTGAAATGCAGGTTGTGTGATCAACCATTTTCAAGCCTAGAAGAGATTCAGACACATTTGGGAACTATACATAGTATTAGTTTCATAGTCGATGCCGGTAATGGAATGATTGCCTTTAATTTGAAGACGAATAATGATCTGTTCACGTGCCATATTTGTACCAAAACATTTCAAAGCTTTTTTCTTCTGAATAAGCATATAAGCGTGCACTATAGTAACGCAGTTTGCGATTCCTGCGGTAAAGGATTTCTGTCACACCAAAGATTAATGACACATATGGAGAGCCATCGCAACGGTACATATCCTTGCGAAAAATGCAAGAAAGTTTTCCCGAGTACATCCAAATTGAAGTATCACAATGGTAAAGTCCACGGCACTTTAGGTAAAGCTAAGCTAGCCAAATGCCAGAAATGTTTAGCCCGATTTGAACACCATTACGAAAAGATTAAACATTTGAAGGAAATTCATGGAGTATCATTTACGTTTACATGCGATACTTGTAATTTGGTGTTCAAAACTCGGCATTCATTGAACATGCACGTAGTCAAGAATCATACTCAGAATATTGTATGTGATATTTGTAGGAAAACTTTTTCAGAGCGGTACCATTTGAGGAAGCATATGGCTATTCATAGTCATGAAAGAAATTTCGTCTGTCCGCTGTGTAAAAAGTGTTATAGATATGAAAAGACTTTGAAGCAACATTTAAAAATCCACAATCCAGATTGGAAGTTTTCTTGCTCCATCTGTTGGATGagtttttctaataaaattgattataaGAGACACAAATCAACaatgcatttataa
- Protein Sequence
- MTILERYNAAKFISYTTVRPFKFMGSSFKCFFCTHYFSEINHLLEHTSTHEVIDEEIILEKYVPKGKRTLQVDISKLQCRLCDQPYLNLNKIRNHLKTEHQKEFAPVGNGMTEYIMEAQNGSFICHMCDMSFPSFPLYNSHINSHVGKVVCDFCGVGFLNQHILRTHKASHVTKDFRCKECDRVFVKKSQLKYHDDIVHKGKDRVRLKKCHLCPQTFKEHYSKMVHLKQVHGIVKSFSCHVCKSVYSTRRALTEHTTKSHTEKYKCKVCSKCFGIESKLKLHLRGHTVAPPRVLPTSSKWSMTLAERINAAYILKNTTVTPFTYLLFPSSYKCLYCDEKYLEIHILLEHSRNHVVPSHDKILKDILKKGKKKIKVDISNLKCRLCDQPFSSLEEIQTHLGTIHSISFIVDAGNGMIAFNLKTNNDLFTCHICTKTFQSFFLLNKHISVHYSNAVCDSCGKGFLSHQRLMTHMESHRNGTYPCEKCKKVFPSTSKLKYHNGKVHGTLGKAKLAKCQKCLARFEHHYEKIKHLKEIHGVSFTFTCDTCNLVFKTRHSLNMHVVKNHTQNIVCDICRKTFSERYHLRKHMAIHSHERNFVCPLCKKCYRYEKTLKQHLKIHNPDWKFSCSICWMSFSNKIDYKRHKSTMHL*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00985412;
- 90% Identity
- iTF_00985412;
- 80% Identity
- -