Math039926.1
Basic Information
- Insect
- Mellicta athalia
- Gene Symbol
- -
- Assembly
- GCA_905220545.1
- Location
- HG992204.1:10464066-10467069[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 0.00089 0.11 14.3 4.3 1 23 155 178 155 178 0.98 2 17 0.00015 0.019 16.8 2.1 1 23 187 210 187 210 0.97 3 17 0.035 4.3 9.3 0.8 2 23 223 245 223 245 0.97 4 17 0.00062 0.077 14.8 0.8 1 23 254 277 254 277 0.97 5 17 4.4e-05 0.0054 18.5 1.3 1 23 289 312 289 312 0.97 6 17 1.4e-05 0.0017 20.0 0.7 2 23 342 364 341 364 0.97 7 17 0.00046 0.056 15.2 1.3 2 23 374 396 373 396 0.96 8 17 0.065 8.1 8.5 1.7 3 19 402 418 400 421 0.92 9 17 0.0007 0.087 14.7 2.3 2 21 426 445 425 448 0.94 10 17 0.012 1.4 10.8 1.4 2 23 457 479 456 479 0.95 11 17 0.0011 0.13 14.1 2.6 1 23 484 507 484 507 0.95 12 17 5.3e-05 0.0066 18.2 0.9 2 23 518 540 517 540 0.96 13 17 0.0001 0.012 17.3 0.7 1 23 567 590 567 590 0.94 14 17 0.0063 0.78 11.7 1.1 2 23 624 645 623 645 0.97 15 17 2.6 3.2e+02 3.4 0.5 3 23 653 675 651 675 0.89 16 17 0.017 2.1 10.3 0.2 1 23 711 733 711 733 0.97 17 17 0.21 26 6.9 2.0 1 23 739 762 739 762 0.96
Sequence Information
- Coding Sequence
- atgtcaataaaagAAGAGAAAATAGAtgttaaagatataaaaattgaaaaacacgATGAAGACAGGAAAGACCCGACATTCTTTTTACCAGAGGAGCCGATGACGTAcgaaattaaaactaaaaagaagaaaaaaaagaaaaaacaggAGGATCCATTTAAAGATATCGAAGAAAAAGTTTCATTACCCACACCTACAGTTTACGATCCAAACAATGACACAGAGTTCGAACCGGTCTTGGATCCAGAAGTCAATATAAAAGTTGAAAATATTGAAGTAGAATTGGATTTTAATGATtttGCTAATGACAATGGATTGATGGTAGAAGGTCCACAAAGTGAAGATAGTCAAGAGCCAGCTGTGAAAATAGAAGAACAAAATCGCGAAGCAGTCCTTTTAACATTCGAAAGCATAATAAACGATAAAAGCGTCATAGGTTTCGGTCCGACTCCAGCCCCAAACTACGTGTGCAAAATTTGTCATCTAGTCTTTCAAACGACAAAAACACTTAGAATGCACCAGAAGAGAAAGCATAAAGTATTCAGGAAATCATTCAAATATATATGTCATTATTGTTCAATGTCGTACGAACAAAAGAATAGTCTCGTCGCCCATATCAAAAGGAAACACGGTCCAGATGCAGCGAATGATGACGGCGAAGAGAGAACTTGTGACGTGTGTGCGTTAGTTTTCAAAGGTATGACCAGATTACGAATGCACATGCGGAGAAAACATGGATCCTTTGAGGAGTCGTTCAAACATGTTTGCGAAGAATGTGGCTTGACGTACGACAAATATAGAAGTCTCATTGTACATATACAGAGAAAACATACGAATGAGAAAAAGCCCGTTATAGATCAGTGGTACAATTGTCCCTTCTGTCCAAAAGTCTTCACAAAAAGGGAAACGTATGCGAGACACGTTCAAAGGAAACATCGAGTTGATGATGAAGACGATGGGAAGCCAGATGATGAAActaaaatgctattaaaaaattgcaaaaacgAAGAGACGGGAGAAATTACTTGTAAAGAATGCCCTCTAGTCTTTTCCTCGCTCAATTATTTAAAGCTTCACATGAGAAGAAAGCATAATGCGTTAAAAGAAGATTTTCGTCTCAAATGTAGAATCTGCAATTTGTCCTATGACAAAATCGAAAGCTTAAAGCGGCATATACGAAGGAAACACGATAAAGGGTCGCATTGTGAAGTGTGCGATAAACAATTCGAAACTAGGGATATGTATTTAACTCATTCACACAAAAGAACGATACAGGAATGTAATATATGTGGATTAGTGTTTGCGTCTCGAGGCGGTTTGTGCAAACATTTGCGTTGTACGCATAAAATACAGTCACCAAAAACGATTGTTTGTACCTTGTGCAATGAAACTTTCCACGATAAACGACAACTGAAGCCTCATTACATGAAAGTCCATTTGAAAGTCTCGTACACTTGCAACTTCTGCAAAAAGATATTCAAAGCGAAGGAAAGTTATCGGCGACACGTATTATTGAAACATCCGACGAGCAAACCAAAAAGTGATCGCCAAAGTTGCGATCAGTGTAACGAAACGTTTAGCGATGAATTTGAGTTGTGTCGTCACATAAATATAGCGCACGGAAAGTCGCAGACCGGTGAGATAGGGGCTCTGTCGTTGCTTGAAATTAAAAAGGAAGAAGTCGAAATTCCGGACACTTTCCAGTGTTCGAAATGTCCCGAAAATTATAGCAATTGGGAACAGTTGAAATTACATTACGAGCAGAATCATCAAGTAGTACCTGAAACGCAGTGCCAAGTGTGCGGTGAATTGATACCAGGGAACGAATTGCAGAAGCATTTGAAAGCATTACACACTGATACAACAGTTCGGTGTAAATATTGCGAATTTGAAACGAATAATCGCGCCAGTATGACGCAACATATGTTGAGACACAAAAACGCGACTACAATCAACTGTGATTTCCCTGGTTGTAAATACAAAACGTTCTATGAGGTTGCCATGGAAAAGCATAAAAGAAAGCATGCTGATCAAGGTGTGAAACTCCAGTGCAGCCAATGTCCTTTCCAGACGATGAACAAGTATATCTTAAAATATCATGAAGAAGCCCATGTAACGGGTAAAAAACGTTACTCCTGTGATCAATGTGATTATGCAACAATATTGCCAGCGAACTTAGTTcaacataaatataaacattCCTCGGAGAAGAGGTTCAAATGCGAAGTCTGTCCATTCGCAACAAAGTACAATACGTCGTTACGTTTCCATGTTAAGAAGAAACATTGTGATCTCCCAACATTCAGTTAA
- Protein Sequence
- MSIKEEKIDVKDIKIEKHDEDRKDPTFFLPEEPMTYEIKTKKKKKKKKQEDPFKDIEEKVSLPTPTVYDPNNDTEFEPVLDPEVNIKVENIEVELDFNDFANDNGLMVEGPQSEDSQEPAVKIEEQNREAVLLTFESIINDKSVIGFGPTPAPNYVCKICHLVFQTTKTLRMHQKRKHKVFRKSFKYICHYCSMSYEQKNSLVAHIKRKHGPDAANDDGEERTCDVCALVFKGMTRLRMHMRRKHGSFEESFKHVCEECGLTYDKYRSLIVHIQRKHTNEKKPVIDQWYNCPFCPKVFTKRETYARHVQRKHRVDDEDDGKPDDETKMLLKNCKNEETGEITCKECPLVFSSLNYLKLHMRRKHNALKEDFRLKCRICNLSYDKIESLKRHIRRKHDKGSHCEVCDKQFETRDMYLTHSHKRTIQECNICGLVFASRGGLCKHLRCTHKIQSPKTIVCTLCNETFHDKRQLKPHYMKVHLKVSYTCNFCKKIFKAKESYRRHVLLKHPTSKPKSDRQSCDQCNETFSDEFELCRHINIAHGKSQTGEIGALSLLEIKKEEVEIPDTFQCSKCPENYSNWEQLKLHYEQNHQVVPETQCQVCGELIPGNELQKHLKALHTDTTVRCKYCEFETNNRASMTQHMLRHKNATTINCDFPGCKYKTFYEVAMEKHKRKHADQGVKLQCSQCPFQTMNKYILKYHEEAHVTGKKRYSCDQCDYATILPANLVQHKYKHSSEKRFKCEVCPFATKYNTSLRFHVKKKHCDLPTFS*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01033959;
- 90% Identity
- iTF_00695898;
- 80% Identity
- -