Basic Information

Insect: Mellicta athalia
Gene Symbol: ZNF296
Assembly: GCA_905220545.1
Location: HG992200.1:3654922-3673081[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.03 3.7 9.5 0.4 3 23 139 160 137 160 0.92

2 14 0.016 2 10.4 2.5 1 23 277 299 277 299 0.99

3 14 0.00016 0.019 16.7 0.9 1 23 305 328 305 328 0.96

4 14 0.038 4.6 9.2 4.7 1 23 333 356 333 356 0.94

5 14 1.6e-06 0.00019 23.0 0.2 2 23 529 550 528 550 0.97

6 14 0.00023 0.028 16.2 1.3 1 23 556 578 556 578 0.99

7 14 0.31 38 6.4 4.9 1 23 637 659 637 659 0.96

8 14 0.0022 0.27 13.1 1.3 1 23 694 716 694 716 0.95

9 14 0.0028 0.34 12.8 3.8 1 23 722 744 722 744 0.97

10 14 0.00065 0.08 14.8 2.1 1 23 753 775 753 775 0.98

11 14 0.00059 0.073 14.9 0.6 3 23 823 843 822 843 0.97

12 14 0.067 8.2 8.4 5.8 1 23 860 882 860 882 0.95

13 14 1.9e-06 0.00023 22.8 0.7 1 23 888 910 888 910 0.98

14 14 6.3e-07 7.8e-05 24.2 3.1 1 23 916 939 916 939 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.03	3.7	9.5	0.4	3	23	139	160	137	160	0.92
2	14	0.016	2	10.4	2.5	1	23	277	299	277	299	0.99
3	14	0.00016	0.019	16.7	0.9	1	23	305	328	305	328	0.96
4	14	0.038	4.6	9.2	4.7	1	23	333	356	333	356	0.94
5	14	1.6e-06	0.00019	23.0	0.2	2	23	529	550	528	550	0.97
6	14	0.00023	0.028	16.2	1.3	1	23	556	578	556	578	0.99
7	14	0.31	38	6.4	4.9	1	23	637	659	637	659	0.96
8	14	0.0022	0.27	13.1	1.3	1	23	694	716	694	716	0.95
9	14	0.0028	0.34	12.8	3.8	1	23	722	744	722	744	0.97
10	14	0.00065	0.08	14.8	2.1	1	23	753	775	753	775	0.98
11	14	0.00059	0.073	14.9	0.6	3	23	823	843	822	843	0.97
12	14	0.067	8.2	8.4	5.8	1	23	860	882	860	882	0.95
13	14	1.9e-06	0.00023	22.8	0.7	1	23	888	910	888	910	0.98
14	14	6.3e-07	7.8e-05	24.2	3.1	1	23	916	939	916	939	0.98

Sequence Information

Coding Sequence: ATGAATGAAAACATGGCACCCGAGGTAGATCCTTTGAGCACGTATAACTTAAGTTCTTTTCACAATTTTGAAAGTTACGAAAATGTACCATACGGAGACAACGCTTACCCATACCACGTTAAATTAGAACAATATCAGAATCCTTTTAACTTTTACAACAATGTACCACATTGTAGCGCTAAAGCTGACCCACAACCAGACAATACAGACAAACATAATAAcgatataaatacaaataatgatATAAATGCTAGCAAAGAACAAATCCAACCAAATAATAGTAACGATAACTTAAACgtaaatatagatataaaaccAGAAATAACACAGAATATCACTAAacggaaaataaaaaaagaaaggaGTAAATACTTCTCCGAGAAAATAACGGATAAAGAGTACTCATTCTACGGATGCTCGGTATGTAACATATCATACAAAACATTACATGAATTAGACGCGCACGTGACAAACGaacataaaaatagaataacGAGCTACGATCTGAGGATAAAGAATCAAATTAGGAAGAAGAAGTTGAAAAAAGAacagaagaagaaaaagaagaaaatgaAGAATATCATCAAAGTGGAGAACGAGATTGAGATAGATATAAAGCCGGAGGAAGGTTACATTGGTAACGAAAAGGCAACGGATTTCTTGAATAACACGGAGTCGGATAACCAGAGCTCGAAAGAGAATGAAAATGGTAAAACAAATGGGAAggtaaatgataaaaatgtaacggaagaaattaaaaatgtaacggaagaaattaaaaatgataGTTTAACGAATAAACAGGAGTTGCAGAATTTACAGAAGATATATAAGTGCTTCGCCTGTCAGAAACAATTCATGTTGAGTTATTATTTGAAATTGCACGTCAGATCTCACACGGatgaAAAGCCCTACACGTGCGCGCAGTGCGGTCAGTCGTTCATAACCGCTAGCAAGCTGGGACGGCACAATAAGAGGTTTCATCTAGCCATCAGATATCAGTGTCGGATATGTTACAGATATTTCTCcagatttgaatttttaactcgTCACTTTGACAAGAAACACCCGGATGATAAATTAGAAGGTGAACCGTATGATTACAACGCAATTCTGCCATATTTAAAAGAACTAGAAGAACAGCTCCGTGAAAAATCTGAAAATGAAAAGGCGAAACCTAAAGACGAAGATCTTTGGTCGAGTGACTGGCCACCGAGTGAGGTTACAGGTATCACTGATGATTTAAAAGTAGAGGTGGTAAAAGAGGAGACAGAACTAAAGATTGAAGAGGTCAAGGTCGATATGGCGGATGTCGAGGTGAAGGAAGAGGAGATCGAGGATAGGAATGACTTCAGGGATGACTTCGGGGATGACTTCAGGAATGACTTCCAGGATGACGTCAAGGATGACGTTAAAAATGATATCAGTGAAGTTAAAGATGTTTTCAACGATGATTTTAAGGATGAGAACGCATCGGACGACGACTACTTCCCCTCAAACACATGGGCGGCTCCCGTTTTATCCCCGGGGGGTGGAGGCACGGGGGTGTCAACTACGGGGGGTTCGGCCGGTGTCGACAAGTTACAGTGTGGTGAATGTGGCAAGAAAGTCAGCAGTGCCTCGTATTTGAGGGTCCATATCCGGACCCACAGCGGGGAAAGGCCGTATAAGTGTTACGTGTGTGGAGCAGGCTTTATTACGTCTAGCAAGATGCATCGGCACGTTCTGACGCACCCGCAGTGCTGGGAGGACGATCAAGTGAAAACtgaaaatatagaaataaaattggaaAAGGAAGGCGAGGCGGTAGACAAAGATACAAAATTAAAAATGAAGAAGGCTCTCGCGAAGTTTTCCAAAAAGTCGAAAAATTCGGAAAAGAAAAAGAAGCTTTATCAAAAGCGGCCGCACGCTTGCGAGTTCTGTCAGAAGAGATTCTTACATTTGGAGACGTTACAGGTGCACAAGAAGTCCCACGAGGGCGAAGCCCTGGTGCACAAGTGTACGTTCTGCCTGGAGGAGCTGCCGGACGCGGAGGCGCGCGCGCGCCACGAGGCCGCGCACTGCGGACCGAAGCCCTACCTCTGCACCATCTGCGGGAAGGGCTACAAGAAGCGGGAGACCATGATATACCACAGGAAGAACCACAAGCCGGACAAGGAGTACATCTGCGACATCTGCACCAAGACGTTCAACGCGCACTGCAAGCTGCAGCGACACATCGTGTCGCACCGCGCCGACCGCTTCGTGCTGCGCTACGAGTGTCCGGTGTGCGCACACATGTTCAACACCAAGTACCACGTGCAGATGCACCTCGCCACGCACCAGAAGGAGGGCCTAATCCAAGAAGAAAACCGCAACGAAATACTAGCGATGGTTTTACAGAACGCGAGGAAAATACCTAAGACCCCAGACGCGCCGGCCGCACTGACAGACATAGTGCCTACAGACGAGCGGAGTCGCATATGCAACATATGCGGGGAAATATTCCAACATTTCTACTACTTAGAGGAACATTTAAAAAGCCACGGCTCGAAAATAGCGATCGAAGACATCGAAAAAGACAGCGAGAAAAAGCACATATGCAAAGTATGCAATAAAGGATTCAAATTGCATTACTATTTGAAACTGCACAGCTTCACACATACAAAGGAAAAGCCCTTCATATGCCAGCAGTGCGGCAAAGGTTTTATAACTAAGGGCAAACTCAAAAGGCACTTAGAAACTCATACTGGACTCAAAAAATATCAATGTCATATTTGTTATAAGTTCTTTACTAGGCCCAGTTATCTGAGGATTCATGTTAGGACCATACATGGGACCCAGGATTATAATTTTAGGCTTGAGAAACAGTATGGGTTGTCATCTGTACCGGTTGTGGGGCATAGCGTTTGA
Protein Sequence: MNENMAPEVDPLSTYNLSSFHNFESYENVPYGDNAYPYHVKLEQYQNPFNFYNNVPHCSAKADPQPDNTDKHNNDINTNNDINASKEQIQPNNSNDNLNVNIDIKPEITQNITKRKIKKERSKYFSEKITDKEYSFYGCSVCNISYKTLHELDAHVTNEHKNRITSYDLRIKNQIRKKKLKKEQKKKKKKMKNIIKVENEIEIDIKPEEGYIGNEKATDFLNNTESDNQSSKENENGKTNGKVNDKNVTEEIKNVTEEIKNDSLTNKQELQNLQKIYKCFACQKQFMLSYYLKLHVRSHTDEKPYTCAQCGQSFITASKLGRHNKRFHLAIRYQCRICYRYFSRFEFLTRHFDKKHPDDKLEGEPYDYNAILPYLKELEEQLREKSENEKAKPKDEDLWSSDWPPSEVTGITDDLKVEVVKEETELKIEEVKVDMADVEVKEEEIEDRNDFRDDFGDDFRNDFQDDVKDDVKNDISEVKDVFNDDFKDENASDDDYFPSNTWAAPVLSPGGGGTGVSTTGGSAGVDKLQCGECGKKVSSASYLRVHIRTHSGERPYKCYVCGAGFITSSKMHRHVLTHPQCWEDDQVKTENIEIKLEKEGEAVDKDTKLKMKKALAKFSKKSKNSEKKKKLYQKRPHACEFCQKRFLHLETLQVHKKSHEGEALVHKCTFCLEELPDAEARARHEAAHCGPKPYLCTICGKGYKKRETMIYHRKNHKPDKEYICDICTKTFNAHCKLQRHIVSHRADRFVLRYECPVCAHMFNTKYHVQMHLATHQKEGLIQEENRNEILAMVLQNARKIPKTPDAPAALTDIVPTDERSRICNICGEIFQHFYYLEEHLKSHGSKIAIEDIEKDSEKKHICKVCNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRLEKQYGLSSVPVVGHSV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00843735;
90% Identity: iTF_00985373;
80% Identity: -