Mcix000244.1
Basic Information
- Insect
- Melitaea cinxia
- Gene Symbol
- ZNF296
- Assembly
- GCA_905220565.1
- Location
- HG992236.1:2149777-2167340[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.027 2.9 9.3 0.6 3 23 132 153 130 153 0.92 2 14 0.012 1.3 10.4 2.5 1 23 263 285 263 285 0.99 3 14 5.7e-05 0.0061 17.7 0.6 1 23 291 314 291 314 0.96 4 14 0.028 3 9.2 4.7 1 23 319 342 319 342 0.94 5 14 1e-06 0.00011 23.2 0.2 2 23 511 532 510 532 0.97 6 14 0.00017 0.018 16.2 1.3 1 23 538 560 538 560 0.99 7 14 0.23 24 6.4 4.9 1 23 619 641 619 641 0.96 8 14 0.0016 0.18 13.1 1.3 1 23 676 698 676 698 0.95 9 14 0.00019 0.021 16.0 1.9 1 23 704 726 704 726 0.97 10 14 0.00048 0.051 14.8 2.1 1 23 735 757 735 757 0.98 11 14 0.00044 0.047 14.9 0.6 3 23 805 825 804 825 0.97 12 14 0.05 5.3 8.5 5.8 1 23 842 864 842 864 0.95 13 14 1.4e-06 0.00015 22.8 0.7 1 23 870 892 870 892 0.98 14 14 4.7e-07 5e-05 24.3 3.1 1 23 898 921 898 921 0.98
Sequence Information
- Coding Sequence
- ATGAATGAAAACATGGCACCCGAGGTTGACCCATTGAGCACGTATAACTTGACTTCTTTTCACAATTTCGAAAGTTACGAAAATGTACCATACGGAGAAAACACTTACCCATACCACGTTAAATTAGAACAATATCAGAACCCTTTTAATTGTTACAACAATGTACCACAGAGTAGCGCTAAACCTGACCCACAACCAGACAATACACACACGAGTACCGATATAAATGCAAGCAAAGAACAAATCCAACCAAATAACAATAACGATAACTCAAACCAAAATATAGATATAAAACCAGAAATAACCCAAAATATCACTAAACGGAAAATAAAAAAAGAAAGAAGTAAATACTTCTCCGAGAAAATAACGGATAAAGATTACCCATTCTATGGTTGCTCGGTATGTAACATATCATACAAAACATTACATGAATTAGACGCGCACGTGACGAACAAGCATAAAGATAGAATAACGAGCTACGATCTGAGGATAAAGAATCAAATTAGAAAGAAGAAGTTGAAAAAAGAACAGAAGAAGAATAAGAAGAGAATGAAGAATATCGTCAAAATGGAGAAGGAGATTGAGATAGATATAAAGCCGGAAGAAGGGTACATTGGAAACGAAAAGGCAACGGATTTCTTGAATAACACGGAGTCAGATAACCAGAGCTCGAAAGAGAATGAGAATGGCAAAACAAATGGCAAGGTAAATGATAAAAATGGAACGGAAGCAATGAAAAATGATAGTTTAACGAATAAACAGGAGTTGCAGAATTTACAGAAGATATATAAGTGCTTCGCCTGTCAGAAACAGTTCATGTTAAGTTATTATTTGAAATTGCACGTCAGATCACACACAGATGAAAAGCCCTACACCTGTGCAGAGTGCGGTCAGTCGTTCATAACCGCTAGCAAGCTCGGTCGGCACAATAAGAGGTTTCACCTAGCCATCAGATATCAGTGTCGGATATGTTACAGATATTTTTCGAGATTTGAATTTTTAACTCGACACTTTGACAAGAAACATCCGGATGATAAATTAGAAGGTGAACCGTACGATTACAACGCAATTCTGCCATATTTAAAAGAATTAGAAGAACAGCTCCGTGAAAAATCTGAAAGTGAAAAGGCGAAACCTAAAGACGAAGAACTTTGGTCGAGTGACTGGCCGCCGAGTGAGGTTACTGGTATCGCTGATGATTTGAAAGAAAGGGTGATAAAAGAGGAGACAGAGTTAAAGATTGAAGAGGTCAAGGTCGATATGGGGGATGTCCAGGTGAAAGAAGAGGAGGTTGAGGATAGGGATGACTTCAGGGATGACTTCGGGGATGACGTCAAGGATAACGTTAAGGATGACGTTAAAAATGATATCAATGAAGTTAAAGATGTTTTCAACGATGATTTTAAGGATGAAAACGCATCGGACGACGACTACTTCCCTTCAAACACATGGGCGGTCCCTGTTTTGTCCCCGGGGGGTGAAGCCACGGGGGGGTCAACTACGGGGGGTTCGGCGGGTGTCGACAGGTTACAGTGTGGTGAATGTGGCAAGAGGGTCAGCAGTGCCTCGTACTTAAGGGTCCATATCCGGACCCACAGCGGGGAAAGGCCGTATAAGTGTTACGTGTGTGGAGCAGGCTTTATTACGTCTAGCAAGATGCATCGGCACGTTCTGACGCATCCTCAGTGCTGGGAAGACGATCAAGTGAAAACTGAAAATATAGATATAAAGTTGGAAAAGGAAGGCGATGCGGTAGACGAAGATACAAAATTAAAAATGAAAAAGGCTCTCGCGAAGTTCTCCAAAAAATCGAAAAATTCGGAAAAGAAAAAGAAGCTTTATCAAAAGCGGCCGCACGCTTGCGAGTTCTGTCAGAAGAGATTCTTACATTTGGAAACGTTACAGGTGCACAAGAAGTCCCACGAGGGCGAAGCCCTGGTGCACAAGTGCACGTTCTGCCTGGCCGAGCTGCCGGACGCGGAGGCGCGCGCGCGGCACGAGGCCTCGCACTGCGGACCGAAGCCCTACCTGTGCACCATCTGCGGCAAGGGCTACAAGAAGCGGGAGACCATGATATACCACAGGAAGAACCACAAGCCGGACAAGGAGTACATCTGCGACATCTGCACAAAGACCTTCAACGCGCAGTGCAAGCTGCAGCGGCACATCGTGTCGCACCGCGCGGACCGCTTCGTGCTGCGCTACGAGTGCCCGGTGTGCGCGCACATGTTCAACACCAAGTACCACGTGCAGATGCACCTCGCCACGCACCAGAAGGAGGGCCTTATTCAAGAAGAAAACCGCAACGAAATACTAGCGATGGTTTTACAAAACGCGAGAAAAATACCTAAAACCCCAGACGCACCGGCCGCGCTAACAGACATAGTACCTTCAGATGAGCGGAGTCGCATATGCAACATATGCGGGGAGATTTTCCAACATTTCTACTACTTAGAGGAACATTTAAAAAGCCACGGTTCGAAAATAGCGATCGAAGACAACGAAAAAAATAGCGAGAAAAAACACATATGCAAAGTCTGTAATAAAGGATTCAAATTGCATTACTATTTGAAGCTCCACAGCTTCACACATACAAAGGAAAAGCCCTTCATATGCCAGCAGTGCGGCAAAGGTTTTATAACTAAGGGCAAACTCAAAAGGCACTTAGAAACTCATACTGGACTTAAAAAGTATCAATGTCATATATGTTATAAATTCTTTACTAGGCCGAGTTATCTAAGGATTCATGTTAGGACGATACACGGGACTCAGGATTATAATTTTAGGCTTGAGAAACAGTATGGGTTGTCATCTGTACCGGTTGTGGGGCATAGCGTTTGA
- Protein Sequence
- MNENMAPEVDPLSTYNLTSFHNFESYENVPYGENTYPYHVKLEQYQNPFNCYNNVPQSSAKPDPQPDNTHTSTDINASKEQIQPNNNNDNSNQNIDIKPEITQNITKRKIKKERSKYFSEKITDKDYPFYGCSVCNISYKTLHELDAHVTNKHKDRITSYDLRIKNQIRKKKLKKEQKKNKKRMKNIVKMEKEIEIDIKPEEGYIGNEKATDFLNNTESDNQSSKENENGKTNGKVNDKNGTEAMKNDSLTNKQELQNLQKIYKCFACQKQFMLSYYLKLHVRSHTDEKPYTCAECGQSFITASKLGRHNKRFHLAIRYQCRICYRYFSRFEFLTRHFDKKHPDDKLEGEPYDYNAILPYLKELEEQLREKSESEKAKPKDEELWSSDWPPSEVTGIADDLKERVIKEETELKIEEVKVDMGDVQVKEEEVEDRDDFRDDFGDDVKDNVKDDVKNDINEVKDVFNDDFKDENASDDDYFPSNTWAVPVLSPGGEATGGSTTGGSAGVDRLQCGECGKRVSSASYLRVHIRTHSGERPYKCYVCGAGFITSSKMHRHVLTHPQCWEDDQVKTENIDIKLEKEGDAVDEDTKLKMKKALAKFSKKSKNSEKKKKLYQKRPHACEFCQKRFLHLETLQVHKKSHEGEALVHKCTFCLAELPDAEARARHEASHCGPKPYLCTICGKGYKKRETMIYHRKNHKPDKEYICDICTKTFNAQCKLQRHIVSHRADRFVLRYECPVCAHMFNTKYHVQMHLATHQKEGLIQEENRNEILAMVLQNARKIPKTPDAPAALTDIVPSDERSRICNICGEIFQHFYYLEEHLKSHGSKIAIEDNEKNSEKKHICKVCNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITKGKLKRHLETHTGLKKYQCHICYKFFTRPSYLRIHVRTIHGTQDYNFRLEKQYGLSSVPVVGHSV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00843735;
- 90% Identity
- iTF_00986486;
- 80% Identity
- -