Math024855.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Mellicta athalia
Gene Symbol
BTBD2
Assembly
GCA_905220545.1
Location
HG992192.1:2108945-2112822[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 6.1e-26 3.4e-23 83.3 0.1 4 109 92 198 89 199 0.94
2 2 1.4 7.9e+02 1.6 0.0 81 109 202 230 196 231 0.86

Sequence Information

Coding Sequence
ATGACTTCCGGTTCCAAGAATGATATTTTGAATCGAGTATTGAACGTGCGGCTTGATGAAGCAGCAGGTGGGGAAGAGCAGCCTCCGCAAAATATGCTGCCGTCAAACCAGCAATCGAGACAAGGCAGTCACGTCGATGAAGAGAACGGTCACGCGAACGAACCTATGCCTTCTTCATCAGCCATCGAGAACCTCCAGCAGACGAACAACACAGGGTGTCGCTTGCACAACTGGCAGGCGACGAAAACGACAGTAAAAGAACGATTGTCATTTCTCTTCAACAACGAAATACTTTCCGATGTTCATTTCATTGTCGGGAAAGACGCCAATCAGCAAGTTATACCCGCGCACAAGTTCGTACTGTCAGTGGGCAGTGCGGTATTCGACGCTATGTTCAACGGAGTGCTGGCTACGAAATCTGAGGAAGTGGAATTACCGGATGTGGAACCGGCGGCGTTTTTACACTTGCTGAAGTTTCTCTATTCGGACGAAGTTAGGATTGGACCGGAAAGTGTCATGACAACATTGTACACAGCTAAGAAATATGCTGTGGCGGCTTTGGAGGAGCACTGTGTAGATTTCCTCAAACGCAACCTCGGGACGGACAATGCATTCTTGCTATTAACGCAAGCGCGGTTGTTCGATGAGCCTCAGTTGGCTGCTCTCTGCTTGGAAATGATAGACAAGAACACAACTGATGCTTTGAATGCTGAGGGCTTTACCGATATTGATCAAGACACTTTGAATGCAGTTTTGGAAAGGGACACGCTACGTATACGAGAAGCAAAAATATTCTCAGCAGTACTTCGCTGGTCGGAGGCTGAATGTATACGAAGACAACTGCCCGTCACACCGAACAACCAAAGAATGGTACTCGGAAGAGCGTTCCACGCCATACGCTTCCCATTGATGTCAGTGGAAGAATTTGCTATGGGACCGGCACAGAGTGGCTTACTAGACGACAGAGAAATAGTTCAGCTCTTCCTTTATTTCACCGTTAATCCTAAACCGAATGTAGGTTTCCTAGATACACCTAGATGTTGTATGACTGGAAAGGAATTGACAGTCAATAGATTCTCCCAAACTGAATCTCGATGGGGTTACAGCGGTACGACTGATAGGATAAGGTTCACCGTCGATCAGAGAATCTTTGTCGTTGGTTTTGGATTGTATGGATCTTACTTTGGGCCCACCGAATATGAAGTTCATTTGCAAATAATTCACTTGGCAACGAAAAAAGTATGCGGTTCGAACACAACAACGTTCTGTTGTGACGGTAGTGACGACACGTTCAGGGCGATGTTCAAAGAACCAGTGGAGATCTTGCCGAACACATCTTACATTGCCAGCACTAAATTAAAGggcACAGATTCTTACTACGGCACAAGAGGTATGAGACGCGTCAGTGTCGACTGCAACAACGGTGAAAAGGTGGTTTTCCAATTTTCATACGCAGCGGGAAACAATAACGGTACATCCGTTGAGGATGGACAAATTCCCgccattatattttatatttag
Protein Sequence
MTSGSKNDILNRVLNVRLDEAAGGEEQPPQNMLPSNQQSRQGSHVDEENGHANEPMPSSSAIENLQQTNNTGCRLHNWQATKTTVKERLSFLFNNEILSDVHFIVGKDANQQVIPAHKFVLSVGSAVFDAMFNGVLATKSEEVELPDVEPAAFLHLLKFLYSDEVRIGPESVMTTLYTAKKYAVAALEEHCVDFLKRNLGTDNAFLLLTQARLFDEPQLAALCLEMIDKNTTDALNAEGFTDIDQDTLNAVLERDTLRIREAKIFSAVLRWSEAECIRRQLPVTPNNQRMVLGRAFHAIRFPLMSVEEFAMGPAQSGLLDDREIVQLFLYFTVNPKPNVGFLDTPRCCMTGKELTVNRFSQTESRWGYSGTTDRIRFTVDQRIFVVGFGLYGSYFGPTEYEVHLQIIHLATKKVCGSNTTTFCCDGSDDTFRAMFKEPVEILPNTSYIASTKLKGTDSYYGTRGMRRVSVDCNNGEKVVFQFSYAAGNNNGTSVEDGQIPAIIFYI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00723265; iTF_01508193; iTF_00213666; iTF_00776802; iTF_00782754; iTF_00780355; iTF_01033859; iTF_01034723; iTF_00695812; iTF_00247333; iTF_01078341; iTF_00159974; iTF_00212678; iTF_00421478; iTF_01181993; iTF_00248235; iTF_00687979; iTF_00420652; iTF_00775372; iTF_00775373; iTF_00781134; iTF_00419855; iTF_00777455; iTF_00843663; iTF_00419089; iTF_01507346; iTF_01080019; iTF_01506483; iTF_00779605; iTF_00824885; iTF_00960278; iTF_00776121; iTF_00778107; iTF_00457342; iTF_00461694; iTF_00621342; iTF_00778846; iTF_00959519; iTF_00985279; iTF_00458176; iTF_00954693; iTF_00256072; iTF_00144774; iTF_00257063; iTF_01079176; iTF_01178760; iTF_00288971; iTF_00744876; iTF_00403954; iTF_00953676; iTF_01080845; iTF_01125601; iTF_01078342; iTF_00925871; iTF_00786927; iTF_00261981; iTF_00781942;
90% Identity
iTF_00776802; iTF_00782754; iTF_00780355; iTF_00695812; iTF_01181993; iTF_00775372; iTF_00775373; iTF_00781134; iTF_00777455; iTF_01507346; iTF_01506483; iTF_00779605; iTF_00457342; iTF_00621342; iTF_00985279; iTF_00458176; iTF_00796641; iTF_00774596; iTF_00954693; iTF_00144774; iTF_00257063; iTF_00256072; iTF_01079176; iTF_01178760; iTF_00897002; iTF_00288971; iTF_00687979; iTF_00420652; iTF_00723265; iTF_00213666; iTF_01033859; iTF_01034723; iTF_00247333; iTF_00159974; iTF_00212678; iTF_00421478; iTF_00248235; iTF_00419855; iTF_00419089; iTF_00960278; iTF_00461694; iTF_00959519; iTF_00744876; iTF_00934950; iTF_01248327; iTF_00406034; iTF_00933971; iTF_01217623; iTF_00953676; iTF_00842797; iTF_01080845; iTF_01508193; iTF_01078342; iTF_00925871; iTF_00786927; iTF_00403954; iTF_01021427; iTF_01092185; iTF_00642490; iTF_00802042; iTF_00164508; iTF_00205308; iTF_00354300; iTF_00353281; iTF_00261981; iTF_00778846; iTF_00781942; iTF_00776121; iTF_01151326;
80% Identity
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