Basic Information

Insect: Melitaea cinxia
Gene Symbol: zfh1
Assembly: GCA_905220565.1
Location: HG992236.1:515656-522607[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 29 0.0017 0.19 13.1 1.4 2 21 166 185 165 186 0.93

2 29 0.38 40 5.7 0.7 3 23 194 214 193 214 0.93

3 29 0.11 12 7.4 1.3 1 23 219 242 219 242 0.96

4 29 0.025 2.6 9.4 1.1 3 23 247 269 246 269 0.91

5 29 0.46 49 5.4 2.7 3 21 274 292 273 293 0.93

6 29 0.00033 0.035 15.3 0.3 2 23 337 359 336 359 0.95

7 29 6 6.4e+02 1.9 0.7 3 23 367 386 366 386 0.72

8 29 0.0099 1.1 10.7 1.4 1 23 392 414 392 414 0.98

9 29 0.0019 0.2 13.0 0.2 1 23 420 443 420 443 0.96

10 29 0.0043 0.46 11.8 1.2 3 23 454 475 453 475 0.97

11 29 3.7e-05 0.0039 18.3 0.4 1 21 593 613 593 614 0.95

12 29 5.7 6.1e+02 2.0 0.3 2 23 619 640 619 640 0.77

13 29 0.011 1.2 10.6 0.2 3 23 647 668 645 668 0.94

14 29 0.00077 0.083 14.2 1.1 1 23 673 695 673 695 0.98

15 29 1.5 1.6e+02 3.8 4.1 1 21 698 718 698 719 0.93

16 29 0.00022 0.023 15.9 0.9 1 23 731 754 731 754 0.93

17 29 0.03 3.2 9.1 3.5 1 23 760 782 760 782 0.97

18 29 3.1 3.3e+02 2.8 0.3 1 23 816 839 816 839 0.87

19 29 0.00084 0.089 14.1 1.6 3 23 848 869 847 869 0.97

20 29 3.8e-05 0.0041 18.3 1.2 2 21 978 997 977 998 0.94

21 29 0.13 13 7.2 0.1 3 23 1005 1026 1004 1026 0.93

22 29 0.39 41 5.7 2.5 1 23 1031 1054 1031 1054 0.97

23 29 5.1e-05 0.0054 17.9 0.8 2 23 1060 1081 1059 1081 0.96

24 29 5.4 5.7e+02 2.1 2.0 2 21 1085 1104 1085 1105 0.90

25 29 0.00014 0.015 16.5 1.4 1 23 1131 1154 1131 1154 0.95

26 29 0.00044 0.047 14.9 0.5 1 23 1160 1182 1160 1182 0.95

27 29 0.097 10 7.5 0.1 1 23 1188 1210 1188 1210 0.97

28 29 0.0052 0.56 11.5 0.8 1 23 1216 1239 1216 1239 0.94

29 29 4.5e-05 0.0048 18.1 2.3 2 23 1246 1268 1245 1268 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	29	0.0017	0.19	13.1	1.4	2	21	166	185	165	186	0.93
2	29	0.38	40	5.7	0.7	3	23	194	214	193	214	0.93
3	29	0.11	12	7.4	1.3	1	23	219	242	219	242	0.96
4	29	0.025	2.6	9.4	1.1	3	23	247	269	246	269	0.91
5	29	0.46	49	5.4	2.7	3	21	274	292	273	293	0.93
6	29	0.00033	0.035	15.3	0.3	2	23	337	359	336	359	0.95
7	29	6	6.4e+02	1.9	0.7	3	23	367	386	366	386	0.72
8	29	0.0099	1.1	10.7	1.4	1	23	392	414	392	414	0.98
9	29	0.0019	0.2	13.0	0.2	1	23	420	443	420	443	0.96
10	29	0.0043	0.46	11.8	1.2	3	23	454	475	453	475	0.97
11	29	3.7e-05	0.0039	18.3	0.4	1	21	593	613	593	614	0.95
12	29	5.7	6.1e+02	2.0	0.3	2	23	619	640	619	640	0.77
13	29	0.011	1.2	10.6	0.2	3	23	647	668	645	668	0.94
14	29	0.00077	0.083	14.2	1.1	1	23	673	695	673	695	0.98
15	29	1.5	1.6e+02	3.8	4.1	1	21	698	718	698	719	0.93
16	29	0.00022	0.023	15.9	0.9	1	23	731	754	731	754	0.93
17	29	0.03	3.2	9.1	3.5	1	23	760	782	760	782	0.97
18	29	3.1	3.3e+02	2.8	0.3	1	23	816	839	816	839	0.87
19	29	0.00084	0.089	14.1	1.6	3	23	848	869	847	869	0.97
20	29	3.8e-05	0.0041	18.3	1.2	2	21	978	997	977	998	0.94
21	29	0.13	13	7.2	0.1	3	23	1005	1026	1004	1026	0.93
22	29	0.39	41	5.7	2.5	1	23	1031	1054	1031	1054	0.97
23	29	5.1e-05	0.0054	17.9	0.8	2	23	1060	1081	1059	1081	0.96
24	29	5.4	5.7e+02	2.1	2.0	2	21	1085	1104	1085	1105	0.90
25	29	0.00014	0.015	16.5	1.4	1	23	1131	1154	1131	1154	0.95
26	29	0.00044	0.047	14.9	0.5	1	23	1160	1182	1160	1182	0.95
27	29	0.097	10	7.5	0.1	1	23	1188	1210	1188	1210	0.97
28	29	0.0052	0.56	11.5	0.8	1	23	1216	1239	1216	1239	0.94
29	29	4.5e-05	0.0048	18.1	2.3	2	23	1246	1268	1245	1268	0.94

Sequence Information

Coding Sequence: ATGACACGGCAAGTGGATGTAAAGGCTCTTGTATCGCATGTAATACGCGGTGACGGTGTAAATAGATGCCGAATATGTATGGGAGATACATCAGAAGGACAAGTGCACTTAGGTGATACAGTTGTAATGGATGGCGAGAGACCTGTACCTCTCTCTGAACTTCTTGAAACCGTTACAGGAATTAAGATGCCGGTAGACGGAGACCTGCCATCCGGAGTATGCCCGGAATGCTCCAAATGTGCCATGAATGCAGCGGAGTTTAGAATGCTATGCCACCATGCCGTCAGCCAATGGGAGATAACAATACAGCTGTTACAGAACCTACCATTGCAACGGAACAACTCAAATAAGACCATGTTTGCTATTATCGATAAAAGTCAAATAACAATTATAAATGACAATACATCTGACTCATTTAGTATCAATACTGCTGCACAGAGATTGACAGAACATTTAAATCCTGACCAAATTAAAAAGGAGAGTAATGTGTTGTGCGAATGTCCCAATTGTGGGAAAGAGTTTCAGTATGCACAGCAGCTAAGTCATCATTTGAAAGAATCGACGGATCATAAACGAGCCTGTCATATATGTGCCAAGATAATGTACCGTGATGATCTGGCTAGACATATGAAAAAGGTCCATAAAAGAAATCCTTATGATTGCAAAAAGTGTCCAGCGTTGCTATCTTCTCATAGTCAGTATGTAAGGCACTTAACGAAGGCGCATACTCGGGGAGCGTGCACGTGTATTGAGTGTGGACGGAGCTTCCAGTCCTGGAATGGTTATCACGCTCATGTCTCTATACACAGACCGAAAAACTGTCCGAGTTGTGACAAGCTATTTAAAAATCAAATGTGCTACGTGCATCATGTGAAAAATTGTTGTAATCTCGACAAGAATAGAGAAGATACCCACCGTACGAAGAACAAAGTAACGGTGGAAGTTAGAAATGAAAGCAGTAAGAGACCTATAAAGGTAGGTCTCCGAGGCAGTGCTGATAAGGAATGTATATGTGATTACTGCGGGAAAAAATTTGCTGGTAAAAAGTCTGTAGCAGCTCATATACAGATAGTCCACATGAAGAATACTCATCGCCCCTGCGTGTACTGCGGCAAGTTTTTAGCAACGGCACACATGACTCAACATGTCAAACAACACCAATTGGACCTGTCGTTCACTTGTGAACATTGCAATGTTGTTCTGAAGACTAAGTTAGGCTATATTCAACATCTACGACTCCACACGGGCGAGAGACCGTACGCATGTGATATATGTGGAGAAACATTTTCGGCTTCATCAAGAAAATCAGAACATATACGTAAAATGCATAAAAGCACAGACATAGTTCTGAAGCAAGCTTGTCACTTGTGCCCAGCTAGGTTCCGTTTGCCATACAGATTGAAGAAGCACTTAAAATCCGTTCACAATAATGATGGGGATGGGTCTGTTCCGCAGTTTGAGTGTAAAGTCGGGCTGGAAACCGAGCTACCGGCCGGAGTTTGCATCCTCTGCACGAACAGCGCCACAGCGGCCTGGCAGTTCAAAAACTTATGCCTCGAATCAGACAAACACTGGAGGAAAACTGTCTTATTACTGACTAAATTACAGTTTCAGCCGACTAGTACAGACAAAACTCTCTTCATAGGCTGTAATACATTGATAAGGGATAATATTGAGAATAAACATCTAAGCGATGCTCTGGATAGGCTGAATTTACTGCTGGGACAAAAGAAAGCGAAAAGAACGAAATACCAAGGAAGTCGAAAGTGTGATGTTTATAAGTGTAAGGACTGCGGGAAGGACTTTTCTATCCCTTATTTTTTGAATCGCCATTTGCTGAGTACGAATAAGCGCGTCTGTAATCTGTGCGGGAAAATTATACCGAAGCAACGCCTCGCTAAGCATTTGTATAAGAGTCACGGCAAACTGGTCGTCAATTGTGATATTTGTGATAAGCTGTACGACGAACAGTTCCAGTTGGAACGCCATAAAGCGATGCTTCACGGGAAGAATTCATTTTCGTGTAATATATGTAAGAATGGTTTTAAAAACGAGAGATCTGTCCGTGCGCATATGTATACGCATACTTTGTTTAATTGTACGTCATGTAACGCCAGCTTCGAGAATCGCAAGTGCTACACGTACCATACACAGCGTTGTGACGGTTCGAAGCAGGCAGCGGAAGGTCATTACGAGTGTCACGATTGCGGCAACGTCTACACGAAAAAGCCATCGTTGAAGATTCACATTGTGCAGAAACATTTGAACGTTTTGCCATACGTTTGCCAGGTTTGTGGCAAACGTAGTTCGACCAAAAACCATCATAAGGCCCACGAGCAAATCCATAAAGCTAAGAGGAAAGTTTATCAATGTTTTTGCGGGGCGAAAATGTTGACAGAATTAGGATTTAACATGCATCAAAGGATACACTCTGGCGAGAAACCGTACGAGTGTGATGTGTGCGGCGACAGGTTTTTGTCAGCTTCGAGAAGGTTAGATCATATCAAGAGGAAACATAGAAGTAAAGAATTCGCTCACGGCTGTAGTCACTGTGATGCTAGATTCATAAGGCCGTTCGAATTAAAAAAGCATTTTAAATCAGTTCATATGATGTCTAACGAGAATTTGTTCCCAAATGGGTTGTGCATATCCTGCACGAGTGTGGCGGTCGCGTCGTACGAGTTCGCAGTGTTAGTTCGTAAATCGCAGAAGCTATGGTCGAACTGTATCAACTCCCTACAAACTCTTCCAACAGTGACCTTAACGCACAAGTCACTATACGTGATTCTAAAAGATAATTTATTAATTCAAACTGTTAATAACTTTGAGGGAGATGCTAAAGATCTATTCGATCACCTAACAAACAGGTTCGTGAAGAGGAAGATAATCACAGAAAGGAAGCCGAGACACCCGAGGGCGGGACCGGCGTGCAGTTGCACGGATTGTGGGAAAAAATTCATCAGCCCGTACTATTTGAATATGCACTTGAGGAACAGTGGCCAGAGGGAGTCTTGCTGGCTGTGTGGCGCTATGTTCACGAGAGGAGATGAGATAAAAGAGCATTTATCAAATATCCATAAGATTACTATGTTTCGATGCACGGAATGCCCGTTACTGTTTAAAAGCGAGCTGGACAGGAAATGGCATGTCAAGAAATGCCACGGTCCTGGCGCGTTGACGTGTAATGATTGTGGTAGAACATTCCAGAGAAAGGGCTCGTTTGAAGTACATTCGCAAATGCACGCAGTGAGAACGTGTAGAGCTTGTGGCTCGCAGTTCTCAAATCGAGGTTGTTACAGAGAACACAGGTCAAAATGTGAACCCAACGCTAAGCCAGATTTGAAGACAATTCCAAGGAATAGGAGATCGAATGTACGCGACCCAGCAACGTTTATATGTGATTACTGCAATAAGACTTATCATTCCCGTCCGCAATTGAAGAACCATATCCTCTGGATACACATGGATATCCGGCCGCATCAGTGTCAGTGGTGCGGTAAGCGTTTTTACACACCAGCTCGATTGGCCGAACACACAGTGGTACATACGCGTGTACGGAATTTCGAGTGCGATATTTGTGGCGCGAAATTGGTATCTAAAATGGCCGCCGTGTACCATAGACGAAGGCACACGGGCGAGCGGCCGTATGAGTGCCAAGATTGTGGTGAAAAGTTCATCTCCTCGTCAAGGAGATCAGAACACGCAAAACGTAGACACAATAGAGGCTCCCGTCTTCAATGTCCAGAATGTCACGCCACTTTTGTAAGAAAGCATGAGCTAAAAAAGCACGTGGACAAAGTACATAATCCTGATAATCAGTTGATGGTGAAAATAAAAAAAGAAAAAAGTTATTCTATAGCTGAAACGACGATTCTTTGA
Protein Sequence: MTRQVDVKALVSHVIRGDGVNRCRICMGDTSEGQVHLGDTVVMDGERPVPLSELLETVTGIKMPVDGDLPSGVCPECSKCAMNAAEFRMLCHHAVSQWEITIQLLQNLPLQRNNSNKTMFAIIDKSQITIINDNTSDSFSINTAAQRLTEHLNPDQIKKESNVLCECPNCGKEFQYAQQLSHHLKESTDHKRACHICAKIMYRDDLARHMKKVHKRNPYDCKKCPALLSSHSQYVRHLTKAHTRGACTCIECGRSFQSWNGYHAHVSIHRPKNCPSCDKLFKNQMCYVHHVKNCCNLDKNREDTHRTKNKVTVEVRNESSKRPIKVGLRGSADKECICDYCGKKFAGKKSVAAHIQIVHMKNTHRPCVYCGKFLATAHMTQHVKQHQLDLSFTCEHCNVVLKTKLGYIQHLRLHTGERPYACDICGETFSASSRKSEHIRKMHKSTDIVLKQACHLCPARFRLPYRLKKHLKSVHNNDGDGSVPQFECKVGLETELPAGVCILCTNSATAAWQFKNLCLESDKHWRKTVLLLTKLQFQPTSTDKTLFIGCNTLIRDNIENKHLSDALDRLNLLLGQKKAKRTKYQGSRKCDVYKCKDCGKDFSIPYFLNRHLLSTNKRVCNLCGKIIPKQRLAKHLYKSHGKLVVNCDICDKLYDEQFQLERHKAMLHGKNSFSCNICKNGFKNERSVRAHMYTHTLFNCTSCNASFENRKCYTYHTQRCDGSKQAAEGHYECHDCGNVYTKKPSLKIHIVQKHLNVLPYVCQVCGKRSSTKNHHKAHEQIHKAKRKVYQCFCGAKMLTELGFNMHQRIHSGEKPYECDVCGDRFLSASRRLDHIKRKHRSKEFAHGCSHCDARFIRPFELKKHFKSVHMMSNENLFPNGLCISCTSVAVASYEFAVLVRKSQKLWSNCINSLQTLPTVTLTHKSLYVILKDNLLIQTVNNFEGDAKDLFDHLTNRFVKRKIITERKPRHPRAGPACSCTDCGKKFISPYYLNMHLRNSGQRESCWLCGAMFTRGDEIKEHLSNIHKITMFRCTECPLLFKSELDRKWHVKKCHGPGALTCNDCGRTFQRKGSFEVHSQMHAVRTCRACGSQFSNRGCYREHRSKCEPNAKPDLKTIPRNRRSNVRDPATFICDYCNKTYHSRPQLKNHILWIHMDIRPHQCQWCGKRFYTPARLAEHTVVHTRVRNFECDICGAKLVSKMAAVYHRRRHTGERPYECQDCGEKFISSSRRSEHAKRRHNRGSRLQCPECHATFVRKHELKKHVDKVHNPDNQLMVKIKKEKSYSIAETTIL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00986481;
90% Identity: iTF_00986481;
80% Identity: -