Mcix005154.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melitaea cinxia
Gene Symbol
BAZ2B
Assembly
GCA_905220565.1
Location
HG992238.1:3933612-3953382[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.7e-11 6.1e-07 29.8 0.0 6 74 204 275 200 278 0.88

Sequence Information

Coding Sequence
ATGGATGAGTCAACAAGTTGCCAGTCTCCAGCTAACACACAAGCTTCGGACGCGTTATCCAGACTAACTTCTCTAAGCAGTTCGCTCAGCGCTTCTAATGACAGAATATCTCGTCGCAAACCAGGCGCCAAACCGAGACGAGTGGCTCCAGAAATGAACTCACATGTAGCGGACTCTCCCAGACCTAAGTCCAGCGGCAGTGAAGATAGTGAATCTGTGTCCACCTGGCCAACGAGGGAAGGAAGGCCTCGCAATTTAGGAAGAGGAGTCAGCAAACCTAAGAAGAACACCGTAGCGTCGTTGCTAGCGCAGAGCAGAGCCCTAGGACTTCGCCCCGCTCTTGCACAGCACTTGCTGGCGGAGACTGACCTGGAAAAGCTACGGGCATTGCTCTGCGAGGGCGCCAGCACGGACTCCGAGTGCCCGTCGGACTCCAACCCGTCCGACTCCGACACCAGCGACCCCGGCCGTCGCCTCGACACCCAGCTGCGCCTGCCGCTGGCGCTAGGTAACTGTCCCGTGCCGCCGGCGGACCGACCGGTAACTGTCCCGTGCCGCCGGCGGACCGACCGGTGTGTGCTCCACTCTCGACCCGTCCGACTGCGACACCAGCTGCGCCTGCCGCTGGCGCTAGGCTGGAAGCGCACGACGCTGATCAAGGGCCTATCACGAAGCTGTCAGCTGAAGGGCGACGTGAGCTACTCGCCGCCCGCCCCCCATCAACATCTCGTTATACGCTCTGCGCAGGAATTACAGGCCTTCCTGGAAGCGAACCCCAGTCCGGCGTTGTCTCGCGATAACTTCAGTTTCAGTGCACGCGCCTTGCTGGGAGATTTCCTCCAGCCCGCTCCCGACGGTTCAGAGCCGTTGTTGCTAGCCGAGGCCGACGTCACGCGCCGGCTGGAGGAGGCGCGCGCGCTGGCGGCGCTGGGCGGGCGGCCCACGCCGCCGCCGCTGGAGCGCCGCATGGAGCTGGCGCGGCGCCAGCAGGCCGCGCGCGACGCGCGCCGCGACGCCGGCCCGCGCCCGCGCGACCAGGCCCGTCTAGTCAGAGAGTTGGAACGCACAGAGAAAGCCGAGCTCGTCAAACGTGAAAAGGAGGCCAGGAGTCAACAGTTGCTGGAGCAAATCAACAAGAATCGATCGCAGCTCACCATCGAGGCTTTACCAACGCCAAAAATAAACGATGAATGGAAAATTCCAGAAATCTTAATGGGACCAGCCACGAAACCCAACAAAGATAGGACGATGCCACAAATAAGCCTATCTCTGATACCGGTCAGTGGTCTCAAGGAAAACATGCCGATAAAAACTATGACCTTAGATCAAAATTGGAAAGAAGAGACCGAGGAATACAATGCGTTGGACAAAATGAAAGATTTCGCTGAAAAAGCCGCTTTCGACTTACCCAAGAGACCGAACGACAAATATTTCGATTTCACACTAACAAAGACCCCGGACAAAAGAAAAGCGCCCGACAAAGAGAACAATCTAGAGAAACTAATCGAATCGTATTCGAGAATAACTGAATTTATAAACGGTTGCGATTGGTCTAAACTGCAGGGCGACAAGAAAACTGACGATCCAAAAAGTCTAGAACAGAAATATTTAGACGCCAAAAACGAATTTATGTCACAAAACCTTATGTTGATGCCGAACGACAATCAGAAAACTGTCCAAAACGTCATCGACTTGAGCGAAGATGATGAATCAGATATTATATCGAAAAAGTTAAACAAAGGGGTAGTTAGTGTGGGGAAAGACGGGGCGTTGTCGATATCGGTACAACCCTTCGGAAAGGACGTTACTAGTCCGGCTAAAAGGAGGAAACAAGAAGAGTTAGAGAAACAGAAGATCGAGGACCAAGCCAAGAGGCAGCAGGAAAGAGAATTGAAAAGACAACAGGCTATGCTTCTAAAAGAACAGCAAAAGTATATAACGGAGGTAAATAACATAGAACGCGAAAGGCGACGCCAGCATACGACGTTCATCCGTCAATTAGATTCTAGAAGACGATGGGAGGAAAGAGAAAGAAGAAAGCACCAGAACCTTCTAGACCGATTGCTTGTTAAGGAGAAGAAATTGCAACAGAGACGGAAAGAGATGGAGTTGCTAGCTGAAATACGACGACCCCAAGAAGATTCCTCTTTATCGGATCAGAAACCGCTACCGACGCTAAACAGAATACCAGGTCTTAAGATATCAGGGCAGGCGATGGCAGATCTCTTGCAAGTGTACGAGTTCCTGCACAACTTTGGACAAGCTCTTGGATTTGTAGTAGAAAATCTACCGTCCCTTAACACCTTACAACTGGGTTTGATACCCAATTGTAATCAAGAGGCTGAGGACGAATTGCTCAGTATACTATCGGCACTTCTTGTTATAGCAATCGAGGAGCCGGGCATCCCGCACCCCGGGCGCCACACCACGCTGCTGGGGCACGCGCTGCGCCTGGCCGAGCCCGCGCCGCACACGCTCAGCGAGGTGCTGCGCATCTACCTGTACGCGCAGGCCACGGCCGAGGTCAAGGCGCTCACCGGACTGACGGTGGAACGCGAGCGTGACCGGCGCGTGGCTGACCATCACCAGAGTGACGCGGAGATGCAGACCGCGTGCGCCAATTCCAAGAACGCGATATACTACGAGCACCTTCACAGCAACGCTACTTACAAGCTGTCGGAGATGCTGCGCGACAAGCCGTTCGTGTCGCTGAGCCCGGCCAGCAAGGCGCGCATGCTGGCGCGCGTGTGCGACGAGCTGCTGCAGAGCCGCGCCGTGCTGCGCCAGCTGGACGCCTCGCTGGAGCAGCTGGCCACGCTGCGCCGCGAGCGCTACCTGCTGGACGCGCGCATCCGCAAGTGA
Protein Sequence
MDESTSCQSPANTQASDALSRLTSLSSSLSASNDRISRRKPGAKPRRVAPEMNSHVADSPRPKSSGSEDSESVSTWPTREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAQHLLAETDLEKLRALLCEGASTDSECPSDSNPSDSDTSDPGRRLDTQLRLPLALGNCPVPPADRPVTVPCRRRTDRCVLHSRPVRLRHQLRLPLALGWKRTTLIKGLSRSCQLKGDVSYSPPAPHQHLVIRSAQELQAFLEANPSPALSRDNFSFSARALLGDFLQPAPDGSEPLLLAEADVTRRLEEARALAALGGRPTPPPLERRMELARRQQAARDARRDAGPRPRDQARLVRELERTEKAELVKREKEARSQQLLEQINKNRSQLTIEALPTPKINDEWKIPEILMGPATKPNKDRTMPQISLSLIPVSGLKENMPIKTMTLDQNWKEETEEYNALDKMKDFAEKAAFDLPKRPNDKYFDFTLTKTPDKRKAPDKENNLEKLIESYSRITEFINGCDWSKLQGDKKTDDPKSLEQKYLDAKNEFMSQNLMLMPNDNQKTVQNVIDLSEDDESDIISKKLNKGVVSVGKDGALSISVQPFGKDVTSPAKRRKQEELEKQKIEDQAKRQQERELKRQQAMLLKEQQKYITEVNNIERERRRQHTTFIRQLDSRRRWEERERRKHQNLLDRLLVKEKKLQQRRKEMELLAEIRRPQEDSSLSDQKPLPTLNRIPGLKISGQAMADLLQVYEFLHNFGQALGFVVENLPSLNTLQLGLIPNCNQEAEDELLSILSALLVIAIEEPGIPHPGRHTTLLGHALRLAEPAPHTLSEVLRIYLYAQATAEVKALTGLTVERERDRRVADHHQSDAEMQTACANSKNAIYYEHLHSNATYKLSEMLRDKPFVSLSPASKARMLARVCDELLQSRAVLRQLDASLEQLATLRRERYLLDARIRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-