Maur006725.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Meliscaeva auricollis
Gene Symbol
egg
Assembly
GCA_948107695.1
Location
OX403618.1:82599179-82608597[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.8 1.3e+04 -3.8 0.0 31 57 1386 1412 1381 1416 0.80
2 2 2.1e-15 9.9e-12 44.7 0.0 5 75 1687 1750 1683 1752 0.89

Sequence Information

Coding Sequence
ATGGAAGATAAAAAAACTAAAGATTTCACGAAAATAGACTCGATTTCAAGTGATATTGGTTCTCTAGAACACGAGGAAAGTACACCATCGAATGTTGTTTCTCAACCAAATGATGAAAATCTGAACAAAAAAAATTTACCAACAAACACCGAAAGTCGCTCCTCGAGCATGGATACGTCTTCTGCGCACGATAAACAAGATGCCGCCGAATTAACAGAAACTTCTATTGATGATGAAGATTTCGTATTGCGAGTAGAATCAAGTGATTGTGAAAATGAAACACTTGAACTTTCAGTTGCAGTTGCTCGTAAAGAAATTAAATCTGCAAATTTAAACAAATCCGAGACATTATTCTCGGATATAGAGAGTTCCGATGATAGCATTGCCTATGAGTCGGAAGGTAAATCCAAAGTTTCAACAAAAATGATGTCTGCAGACAAGGAAAGAACTCAATCTGATGTGGAGGTAGATGTACCCGCAGATAAGAAAGTAATTGAAACGGAATTTGATCCTGTTGAATCCGATGAGGAATTTTTTGAAGATCCCCCATTGCCGGAGGGAACAGAACAAATTTCACAAGAAAGTATTTCCGACAAATGTTTGGAGGCAGAAGAAAGAAACTCAACTCCATTAATTGATGAAGAAATTGGTGAGTCTACTGAACTTAACTTCGACACACAAGAAGTAATAGCAATGAAAACACCTAAATCCAATCAAAAACCCGATGAAACTGTTGACTTAAATTTAGAAACTTCAGTTGATGTGCAAAAAGACATTTTGGAGGAGTCAACAGAATCTCCAAACCGGAATAAAGATGAAATAACCGCTGAAATTAAAACAAGTAAAGATTTATTTCAAGATGATTCTGAAGAACTGAATGATAAAGGGACAGTAGATAGTCTGAGGCTAGATGAAACGAAAACTGTTTCATCAAGTTCTTTTTTGCTTGAAGAAGAAATAGAAAAATGTCCGCCAAATGAACCAGATATCAACAAAACGGATGAGAATTTAAATTCAACTGACGAAATTTCAAATGATATGACAATGAATCCCCCCAAAGTTTCTACAAAAATCCCTTCGCAAGAAAAAAATACGGAGAAATTAGGAGAAAGTCTGCCAAACGATGGTGCTGAAATAATATCGATGAGTTCTAATCTTGTCGAAAATGAAAACATTTCACCAACAGTTCTACCACAAACAATGGAAACTAATATTGCGATGACAGAGGAAATAAACTCAACTGATGATGAAAATCTTGAAGTAGAAGAATCATTTGTTTCAGTTAGTGAACAAGTGGAAGTAGTAGAACCAATGCAAATTGATGATAGCATTTTGGAAGTCAGTGGAGTTTCAGAAATGGAAACGAATGAAGACCAGCCAACGATTGAAAAAACTGACAAAAGTTCATATGAAAAGGAGCCACAAAATTCAACCGAAAATGAAAAAGCTATAGAAGATGAAATTACTTCAAAAGTGGATGAGACCTCTGGAAAATGTAAAGAAATTTTAGCTGAGATGGAAACCATTTCAGATACTGACGAACCAATAAAGAAAACATCAAAGGAACCAAATAAAGTCCAAGAAAAACCTACGAATACAAAGCCCGAAGAAAAAGTATCAGGCAAAGATTCGGTGAAAATTAGAAAAATGGAGGAAAGAGTGAAATCAAATGAAGAAGATAACTCCAACAAAGAAGCACCTCATTGTGACTCGATTGAAGACATCCCGATGATTGATGCTGACAATACAATATCAGACGATGTTCTTGTACCAACACCAAAATTATCTGCTGATGATGAGATACAACAAGTTGAATGCACTGCAGACGAAAAAGTGGAAAAAGAACATAAAGAAGCAACAGAATCGTTGGAAAAGCCAGATGATGTCAAAAGATCAACGATTGAAGTTCTAGATGAATCTGATATATTTTCGAGCTCTCTTGATGACCCTAAAGCGGTTTGTAATGAAACGTCAGTGGAGAATGACAAAGAATCACCAAAAACATCTGGTGAACAACCTCAAGAAGACACAAAAACTCCATCAGAAATACAAAATGCAGACCTTGATACAACATCACCGGTCATCATTGAGGAATTATTGGAGTCATCAGAGAAAGCAAAAGAAAAGGTTTTGGAATTAATTGAAAAAGAAGAATCTCCAAATAAAATTGAGGAATCAGTTGAAAAATATGTAGAAAGTATTTCAGATTCTCCTAAGGAAGTCGAAAAATTAATTGTTGCGAGTGCTTCATCTTCAACAGAAAAGTTAGAATCTCCCAAAAAATTAGTGGAAACATCTGAGAAATCAAATAAACAACTAAGCGATTCTATTGAAAATAACGAATCTTCTAAGAAAATAGTGGAAATTATTACGGAACCATTGGAAATAGATGAATCTAATCAACAAATTGTAGAAACAGCAAAAAAATTAGTTAAATCAACAAATGATTCTGGCGAAAAAGAAGAACCTTTGAATGAAACAGTTGATTCATCAGAAGATTCAAATAAAGCAGAAGATTCTCCACAAGCACCAGTAGAAGTAGAACAATCTGAAACCCCTAATGTACCTAAAACGACTGAAGAGCAAGAGTCCCCTAAAGAAATTGCTGAATCGAAAAAAACTGCTGATTCAAAGGAACCAACGAAGAAAATTGAAGTGATTAAATCATCAGATGTTATAAGTTCAAATACAGAAACCTTGTCAGAAGCTGTAGAAATACCTGACGTCGCAATGGAAGTTCTTGTAGAAAAAGTTGTTGAAGTTGCAACTCAAATTGAAAGCACAGATTCCAAGGAAATATCCAATTCAGGAGTAAATCAAGATGCAAAGAAATCATCTTCGGTAGTAGATCCTGAAATAATTGAAATTGACGATGATGATGATGATGATGATATTGAAGAGGAGAAAAAGAAAGAAGAAGAAAGCCCAAAAAAAGATGAAAAGGCTGCATCATCATTAACAACAACTGAAAAAGAATTAGGTGCTAAGAAAAACGAAGATGAAGCAACAAAGACTACTGAAAATAAAGAATCAAATGATCTTTCCACTCCCATGGACATCGATGATGAAATTAAAGAAAAAATTCCATCTCAGCCACCAGTAGAAGTTCAACCTTCTGTTGATCAAGATACCAACAAAGTTCCACAATCTGCAGTCAACGACAGCGGCGGAGATGAAAAGTTGAACGACAAAGTAAGTCTACCAGTTTTGGATGATGACGAAGAACCACTGCTAATGATCGATACATCACACATAGAAGACAACGATAATGAGAGTATAATGGACAATGAAACAGCCACATCAGCACCCACAACTGATTCGAGTAGTGATGGTTCGTTGGAACTGTTTTATGACAAGGAATGTATTAACTATGAGTGCAAGCGTGCAACAAAGAACTATTTTCGAGCAACAGTGTTTACATTGAATTACTTTAAAATATCAAAGAAGCGCACCAAGCCACAATTTGTGTGCGAGGATTGTTATGATCGGGCTCTGGGATCGTATGAGGAACTTTGTAAAACACTGAAACAGAAACAACCCCTTTTGCATGGAACAACATTCAAATGTCAAGAATTCGTAGAAATCATTGATAGCAGCGACGAGGAAGAAAGTGATGCTGGAGGAGACAAAATTAAAGATGAAAACACTTTACCAAAAGAAAGCATTGAAATGCTTGAAGCTGAACTTGAAGGAGCCATTCGCAAAGTTATGCACAATGTTGATATCCAAAAACAACTGTCCTGGACAAAGCAAATCTTACAACAGCGTCTAACGAATCTTCAAGAAGATTCAGACTTTGTCACCGAACAATTGCGTGCACTTCAAAGAAAAGCCGATCATATGCATAACTCTCTGTATCAGTGTCCGAAAATAAAGCTTCGTCAACTAACACCTCTGGATTTGAACAGCGGTCGAATGTACAGTCCGGAAACGGATAATTCCACAAGTATGCCACCGCAAGGAGAAATTGTTCGGCCACCAATTTGTGTTAACGAACAATATTATGCTGTGAAGACCAAAGCTATTGCTAGTTGGGTACCGTGCAAAGTAATCGAAGAGGTGGAAGCTTATCCAGTGGCCTATAATCAGTTGAAAACTTATAAAATAAGATTTACAAAACTTGCAAAGTATCCAATGTTCAAGACAGTTTATGCCAAACACATTGCATATTATGATCCACCGAATGTTAGGTTGCCAATTGGATCTCGTGTTATTGCATACTTTGATGCAACATCATTGTCACGGGGAAAGGAGAAAATGCTTATTCCAAGTGCATTCTATCCAGGCATCATTGCAGAACCACTCAAACAAAGCAATAAATTTAGATACTTGGTATTCTATGATGATGGTTATTTCCAGTATGTAAATCACAAAGATGTTCGTTTGGTTTGTCAAGCCTCTGAGAATGTATGGGAGGATGTGCATCATCAATCAAGGGAATTCATTCACAATTATCTTACACAATATGCCGTTAATAGGCCAATGGTACAAACTCAAAAGGGTCAAAGCATGTTGGTCGATTATAATGGCAAATGGATATATGCTCGTGTCATTGATGTGGATTGTAGTTTGGTACAAATGTTATTCGAGGGACAAAGTCGATCTGAATGGATATATCGAGGCTCAACGCGCCTGGGACCTGTTTATAAGGAATCAAATAATCTGTCGCAGAAAAATACGCTAAATGCAACACGAAGGCGCACGGAACCATTTATTCGCTACATAAATGGAGACGATTCATCATCATCACAACAAGTACAAGAGCCCGACCAGGCCCAGGCTAAAGCGGGAAGTAGTGAAATTCGTTCAGTTGCAAAGAAGAGCGTTAGCCGAGTTGATACCTCGAACAATAATAATTCCACTACAAGCAGTGCTTCACAACCAGTGCCAACAGTGCGTCATCTTAATAATTCAACAATTTTTGTCGATGATGATAATAAACCTAAAGGAAAGGTTGTCTACTACACGGCAAGAAAGAACTTACCACCACGTGATTATGTTCCTCATATATGCAATCCAGCCTGCCCGTTTAATATTACCCACAATCTTACATTCTATAGTCCTTTGGCAAAACCATTATTATCTGGGTGGGAACGACAAGTATTTAGACAAAAGTCAAAGAAGTTTATTATATATCGAGGACCTTGTGGTAAACGAATGCGTAATATTGAGGAACTTCACAGATATCTGCGAGTCACTGACAATGAACTGAATGTGGATAACTTTGATTTTAGTCCTGATACTAACTGTTTAGCGGAGTATGTTCTGGAGAAATGCCTTGTTAACAAAAAGGATATCTCATGTGGCAAAGAGAAAATGCCAATTCCCTGCGTAAACTACTACGATGAATCAATGCCACCAGCATGTGAATATTCTGCTGTGCGAATTCCCACTGAAGGTGTCCCATTGAATTTAGATGAAGAGTTTTTGTGTGGCTGCGACTGCGAAGATGATTGTTCGGACAAAACAAAATGTGCATGTTGGCAACTGACTTATGCTGGTGCCAAGTATGGTATGCCTAGTGTGCCCACAGAAATGGTTGGATATCAATACAAACGCTTGTACGAACATGTACCAACGGGAATTTATGAATGCAATCCAAGGTGTAAATGCAAATCAAATTGCGTGAATCGTGTTGTCCAGCAGCCGCTTCAATCAAAATTACAAGTCTTTAAGACATCAAATCGTGGATGGGGTTTGCGGTGTATAAATGATGTACCTCGTGGTTCCTTTATTTGCGTCTATGCTGGTCAAATGCTTACCGAACAGGTTGCAAATGAAGGTGGTCTCGATGCAGGGGATGAATACTTTGCCGAGTTGGATTATATTGAAGTTGCTGAACAAATAAAAGAGGGATATGAATCTGATGTTCATGAACCTGATGAAGAAGAGGATCTTTATAATCCCGAAAGAGAAGACGATGATACTGACTTCCGGGCTTCCTTATCTTATAAAGACAAAGAATTTAATACTCGTTTAAGAGCACGAAGAGGTAATAAAAACAGTACAGATGGCGAGTGTGAATCCCAGGAAAGACAAGTAATAAGCTTCGAGCCGAACAAAAATATGGACACATCAACTGAACCCAATGAAAAACCAACCATACGCAAACTGTTTGGCAAAGATGAAAGTTGTTATGTCATGGATGCAAAGGTCAGAGGCAATCTTGGGAGATACTTTAATCATTCCTGCTCTCCAAATTTATTTGTTCAAAACGTTTTCGTTGATACTCATGACTTGCGATTCCCTTGGGTGGCGTTTTTTGCTTCAACACATATTAGAGCTGGCACAGAGCTTACATGGAATTATAATTATGAAGTGGGCGTGGTACCCGGAAAAGTATTATATTGTCAATGTGGAGCGCCCAATTGTCGACAGAGATTGCTTTAA
Protein Sequence
MEDKKTKDFTKIDSISSDIGSLEHEESTPSNVVSQPNDENLNKKNLPTNTESRSSSMDTSSAHDKQDAAELTETSIDDEDFVLRVESSDCENETLELSVAVARKEIKSANLNKSETLFSDIESSDDSIAYESEGKSKVSTKMMSADKERTQSDVEVDVPADKKVIETEFDPVESDEEFFEDPPLPEGTEQISQESISDKCLEAEERNSTPLIDEEIGESTELNFDTQEVIAMKTPKSNQKPDETVDLNLETSVDVQKDILEESTESPNRNKDEITAEIKTSKDLFQDDSEELNDKGTVDSLRLDETKTVSSSSFLLEEEIEKCPPNEPDINKTDENLNSTDEISNDMTMNPPKVSTKIPSQEKNTEKLGESLPNDGAEIISMSSNLVENENISPTVLPQTMETNIAMTEEINSTDDENLEVEESFVSVSEQVEVVEPMQIDDSILEVSGVSEMETNEDQPTIEKTDKSSYEKEPQNSTENEKAIEDEITSKVDETSGKCKEILAEMETISDTDEPIKKTSKEPNKVQEKPTNTKPEEKVSGKDSVKIRKMEERVKSNEEDNSNKEAPHCDSIEDIPMIDADNTISDDVLVPTPKLSADDEIQQVECTADEKVEKEHKEATESLEKPDDVKRSTIEVLDESDIFSSSLDDPKAVCNETSVENDKESPKTSGEQPQEDTKTPSEIQNADLDTTSPVIIEELLESSEKAKEKVLELIEKEESPNKIEESVEKYVESISDSPKEVEKLIVASASSSTEKLESPKKLVETSEKSNKQLSDSIENNESSKKIVEIITEPLEIDESNQQIVETAKKLVKSTNDSGEKEEPLNETVDSSEDSNKAEDSPQAPVEVEQSETPNVPKTTEEQESPKEIAESKKTADSKEPTKKIEVIKSSDVISSNTETLSEAVEIPDVAMEVLVEKVVEVATQIESTDSKEISNSGVNQDAKKSSSVVDPEIIEIDDDDDDDDIEEEKKKEEESPKKDEKAASSLTTTEKELGAKKNEDEATKTTENKESNDLSTPMDIDDEIKEKIPSQPPVEVQPSVDQDTNKVPQSAVNDSGGDEKLNDKVSLPVLDDDEEPLLMIDTSHIEDNDNESIMDNETATSAPTTDSSSDGSLELFYDKECINYECKRATKNYFRATVFTLNYFKISKKRTKPQFVCEDCYDRALGSYEELCKTLKQKQPLLHGTTFKCQEFVEIIDSSDEEESDAGGDKIKDENTLPKESIEMLEAELEGAIRKVMHNVDIQKQLSWTKQILQQRLTNLQEDSDFVTEQLRALQRKADHMHNSLYQCPKIKLRQLTPLDLNSGRMYSPETDNSTSMPPQGEIVRPPICVNEQYYAVKTKAIASWVPCKVIEEVEAYPVAYNQLKTYKIRFTKLAKYPMFKTVYAKHIAYYDPPNVRLPIGSRVIAYFDATSLSRGKEKMLIPSAFYPGIIAEPLKQSNKFRYLVFYDDGYFQYVNHKDVRLVCQASENVWEDVHHQSREFIHNYLTQYAVNRPMVQTQKGQSMLVDYNGKWIYARVIDVDCSLVQMLFEGQSRSEWIYRGSTRLGPVYKESNNLSQKNTLNATRRRTEPFIRYINGDDSSSSQQVQEPDQAQAKAGSSEIRSVAKKSVSRVDTSNNNNSTTSSASQPVPTVRHLNNSTIFVDDDNKPKGKVVYYTARKNLPPRDYVPHICNPACPFNITHNLTFYSPLAKPLLSGWERQVFRQKSKKFIIYRGPCGKRMRNIEELHRYLRVTDNELNVDNFDFSPDTNCLAEYVLEKCLVNKKDISCGKEKMPIPCVNYYDESMPPACEYSAVRIPTEGVPLNLDEEFLCGCDCEDDCSDKTKCACWQLTYAGAKYGMPSVPTEMVGYQYKRLYEHVPTGIYECNPRCKCKSNCVNRVVQQPLQSKLQVFKTSNRGWGLRCINDVPRGSFICVYAGQMLTEQVANEGGLDAGDEYFAELDYIEVAEQIKEGYESDVHEPDEEEDLYNPEREDDDTDFRASLSYKDKEFNTRLRARRGNKNSTDGECESQERQVISFEPNKNMDTSTEPNEKPTIRKLFGKDESCYVMDAKVRGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFASTHIRAGTELTWNYNYEVGVVPGKVLYCQCGAPNCRQRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-