Basic Information

Insect: Melipona quadrifasciata
Gene Symbol: egg
Assembly: GCA_001276565.1
Location: KQ435789.1:1203409-1207977[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 4.7e-14 2.2e-10 39.7 0.1 5 70 583 642 580 648 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	4.7e-14	2.2e-10	39.7	0.1	5	70	583	642	580	648	0.88

Sequence Information

Coding Sequence: atGGAAATCATTGAACTTGTTTCGGATGATGAAATATCAAAggataatacaaaaaaaaatagaagttcCAAAATTGGCAATAccaattgtataaattttcaatgttcttcTGGAGTAGATATGAAATTAGCACCTTCTTTTGCATGTGCTTTTTATGGAGTAaatacagagaaaaagaaagagcgtATAATATGTACAAAGTGTTTTAATGCTGCTTTAGAACACCAAAagCAATTGGTCACAGCATTTGTGGATCATAAGCCATTGTTGAACTGTGAATTTCCAGATCATACAATGGAAGTAGAAATTTCTGATAGTGACGATTCAGatgatgagaaaaaaaaagatacatgtAATGAGGaaaaatatttaccagAAGAAATGCTTTTAGAAGTAGAAGAAATGTTAGACAGtacattaaacaatatttttaagaagtaTGATGTTGAGTATCAAATTAAACAAGCTCATAGCATACTAAAAGATCAATGGAATAAAATAGATGaacaaaatgaaattctggATAAAACAGTCAAAGATTTGATGTGTACTATGGATACattacgtaataatttatatgatgaATTCAGACCACAAATTGAAATGTTGCAAGAACTTCAAATTGATGATGGATATATGGATAACAGTCTTTATCCATTAGTAGCAACAAAAAAAGTTACCCAAGTAAGAGTTCTTCCTTCAGTTTTACAAGATAGTCAACCAGAAGTTTTACCAATTGAACAAGATAATAAACAAGTTGTGGTTCTGGATTTACCCCCAATTGGCCCAATAGTAAGAGTACAAATAGAAGTTGAtagtattgtatatattatgaaGCATCCACTTATGCCATGGATTAAAGGAAAgGTACAAAATGTACTCTCTAGAACTCCTTTGCACTGTCGTGTAAGATTATTACAAAAGAGATATAATTCTGTTGTTAAATCTGTTTCTGGCAAACAAATTGCAGCTGCTGTAATTAGTCAAGTAATAATTCCAGTTAGTACGCGAGTAGTTGCAGTATTTAAAGATGTTTCATCTAttgccgaattttctaataaagtTTGGGAAGATATACCTAATGAATCTCgtgattttgttaaaaaatatattgaaacataTCCTGAGAGACCAATGGTAAAACTACAAACAGGACAAGTAGTAAAAACAGAATGGAATGGTAAATGGTGGATTGCAAGAGTAGTTCAAGTTGATGCAAGTTTAGTACAAATGCATTTTGATGCTGATGGAAGAACAGAATGGATCTACAGAGGTTCTGCTAGATTAGGACCTTTATATCTTGAACTTTTAAAAGCTAATGCCAGACAACATGGACATCATGCATCTGTTAATACGCCTAGTCGACATCGATTACCTGCTATTTCTAATaaaaaCAATTTACCTTATGTGGAATATACATCTAATCTGGAATCTGAGGAAGAAAGACTTTCtcaattagaaaaagaacagaataCAGTGAATGAAAGTACAAATGCATTATCAAATGTACCACAACAATCACGTGCTGTTGCTAGAAAAAGTACAagtaaaaagcaaaatattgtGGATTCAAATCTTTATAATCCTACGACAGAAACAAAACCTTCTCACAGTATAGTCGTAAGTGTATtgaataaatACTATCAAACACAGAACAAGAttcaaacaaagaaatttgttcCACATAATTGCGGCCCTCAATGCGTTCAGGGAATATCTTTTACGCCTGATGACTTACGAGGTTATTCACCTCTTTCAATACCATTACTCTGTGGTTGGAATAGGCAACTTTGTAAATACCCAAAAggcaaaaaaattacattatatcaaGCTCCGTGTGGTGTTAGGTTACGAAATATGGAAGAATTACATCAGTATCTTCGCAAAACAGGTAGTCCAATGTCAGTTGATCTATTTGACTTTGATTACTGGGTGCATTGTCTAGCAGAATTTGTTTTGGATAAAtgctttattaatataaaggATCTCAGTTATGGTGTAGAAAATGTACCGATACCATGTGTTAATGAATTAGACCACACTCAACCAGATACCATTAGATATAGCACTCAAAGAGAACCAACAGAAGGAGTTAATCTTAATTTAGATCCAAATTTCTTGTGCAGCTGTGATTGTGAAGACGATTGccaaGATAAAACAAAATGTCAATGTTGGCAATTAACAATACAAGGTGCCACTCTTGGAGGAAGAGTGCCAAATACATCTGTCGGTTACGTATATAAACGTTTACCAGAGCCTGTTACTACTGGAATTTATGAATGCAATTCTGGATGTAAATGTGCTGTAAAAACTTGTTTAAATAGGGTAGTGCAACATCCATTAACGTTAAAATTACAAGTATTCAAAACAGCTCCTCGGGGCTGGGGTATACGATGTTTAAACGATATTCCTCTTGGgtcttttatttgtatatatgcTGGTAGATTACTTACAGAACAGGGAGCTAATGAAGGTGGTAAAAATTATGGAGATGAATATTTAGCAGAATTAGATTACGTAGAAGTAGTAGAAAGTATTAAAGAGGGATACGAAAGTGATGTTCTCGAACCAGAAATGCCATTATCTACTCCAgcagataaaaagaaatctataACAAGTGATGATGAGGATAATTCAAAACCAAATGTAAATGATTCGGACGAAGATTTCAATATTAGCAAATACGTGAATTTCAATGTAGATTCTACAGAACCTTCTATTAGAAAGAGATtaaggaaacgaaaacgagatGATGTCAATCAAGATGGATCTGAAGAAAATAGCGAAGATGGAAGTGTTACTAAGACCACAGAAAACATTATGAAGTCTTCTATTAACGAAAACCGCTCAAATGATCCAGATGCAATTACTATAAgtgatgaagaagaaaatagaagtGGTAGACGTGAACCAAGTAGATTTGATCCAACAGTGGAACCAACGCAAATAGAAAgaccaaaatttaaatcagtAAGAGATTTCTTTGGAGAAGACGAAGCTGTTTATATAATGGATGCTAAGACAACTGGAAATATCGGACGTTACTTGAAtcaTTCGTGTGATCCAAATGTTTTTGTGCAAAATGTATTTGTAGATACACACGATGTAAGGTTTCCATGGGTAGCATTCTTTGCATTAAATTACATAAGAGCAGGTCAGGAATTAACATGGAATTACAGTTACGATGTTGGAAGTATACCAGGTAAAGTTATCATATGTAAATGTGGTGCATCTAATTGTAGAGGTCGACTTTtaacattacaagttattttacaaaataaagtaGATGTAGGAAATCTGAAAATCAACTGTATTGTTGAAAATCAACTGTactgtattttacaaatatag
Protein Sequence: MEIIELVSDDEISKDNTKKNRSSKIGNTNCINFQCSSGVDMKLAPSFACAFYGVNTEKKKERIICTKCFNAALEHQKQLVTAFVDHKPLLNCEFPDHTMEVEISDSDDSDDEKKKDTCNEEKYLPEEMLLEVEEMLDSTLNNIFKKYDVEYQIKQAHSILKDQWNKIDEQNEILDKTVKDLMCTMDTLRNNLYDEFRPQIEMLQELQIDDGYMDNSLYPLVATKKVTQVRVLPSVLQDSQPEVLPIEQDNKQVVVLDLPPIGPIVRVQIEVDSIVYIMKHPLMPWIKGKVQNVLSRTPLHCRVRLLQKRYNSVVKSVSGKQIAAAVISQVIIPVSTRVVAVFKDVSSIAEFSNKVWEDIPNESRDFVKKYIETYPERPMVKLQTGQVVKTEWNGKWWIARVVQVDASLVQMHFDADGRTEWIYRGSARLGPLYLELLKANARQHGHHASVNTPSRHRLPAISNKNNLPYVEYTSNLESEEERLSQLEKEQNTVNESTNALSNVPQQSRAVARKSTSKKQNIVDSNLYNPTTETKPSHSIVVSVLNKYYQTQNKIQTKKFVPHNCGPQCVQGISFTPDDLRGYSPLSIPLLCGWNRQLCKYPKGKKITLYQAPCGVRLRNMEELHQYLRKTGSPMSVDLFDFDYWVHCLAEFVLDKCFINIKDLSYGVENVPIPCVNELDHTQPDTIRYSTQREPTEGVNLNLDPNFLCSCDCEDDCQDKTKCQCWQLTIQGATLGGRVPNTSVGYVYKRLPEPVTTGIYECNSGCKCAVKTCLNRVVQHPLTLKLQVFKTAPRGWGIRCLNDIPLGSFICIYAGRLLTEQGANEGGKNYGDEYLAELDYVEVVESIKEGYESDVLEPEMPLSTPADKKKSITSDDEDNSKPNVNDSDEDFNISKYVNFNVDSTEPSIRKRLRKRKRDDVNQDGSEENSEDGSVTKTTENIMKSSINENRSNDPDAITISDEEENRSGRREPSRFDPTVEPTQIERPKFKSVRDFFGEDEAVYIMDAKTTGNIGRYLNHSCDPNVFVQNVFVDTHDVRFPWVAFFALNYIRAGQELTWNYSYDVGSIPGKVIICKCGASNCRGRLLTLQVILQNKVDVGNLKINCIVENQLYCILQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684169;
90% Identity: iTF_00982969; iTF_00733955; iTF_01420934; iTF_00873801; iTF_01417708; iTF_01418352; iTF_01420278; iTF_01418999; iTF_01419643; iTF_00982292;
80% Identity: -