Basic Information

Gene Symbol
-
Assembly
GCA_030673865.1
Location
JAHYIQ010000006.1:5771315-5774713[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0003 0.033 15.2 1.5 1 23 103 126 103 126 0.94
2 13 0.011 1.2 10.3 4.6 2 23 250 272 250 272 0.91
3 13 0.0012 0.13 13.3 2.1 3 23 317 338 316 338 0.96
4 13 5.9 6.5e+02 1.7 7.6 3 23 426 447 425 447 0.95
5 13 0.089 9.8 7.4 1.9 1 23 498 521 498 521 0.94
6 13 9.1e-05 0.01 16.8 0.3 2 23 569 591 568 591 0.95
7 13 0.00053 0.059 14.4 0.0 3 23 615 636 614 636 0.91
8 13 0.0077 0.85 10.8 3.6 2 23 677 699 676 699 0.96
9 13 0.1 11 7.2 4.2 3 23 714 735 712 735 0.92
10 13 0.00026 0.029 15.4 0.1 2 23 780 802 780 802 0.94
11 13 0.048 5.3 8.3 1.6 1 23 882 904 882 904 0.98
12 13 0.0014 0.15 13.1 0.7 2 23 918 940 917 940 0.93
13 13 0.0068 0.75 10.9 0.8 1 23 1014 1037 1014 1037 0.98

Sequence Information

Coding Sequence
ATGTCCTCAACGATGGCGCATGAGACGACGATATCGGAGTTGACGGAATTGGACAGCGACGGATCGAGTTGCGGTGGTGAACGCGACGCGAGGAAACGTCTTCGTTTCGACGTGGACTCGACCGGGCCGAAGAAGAGGCGAAAACAAACGACGCCCGTGCGATTCTCGTCGACGTTGGTGCCCGGCGCGCACGAGGAATCgaacgaggacgaggacgaggacgaggaggacAGCGAAGGTAAGCTGTCGTTGCAATCACCCGTGCCGTGTCAATCGTCGATAAGGGACGAGAACCTGAATAACGAATTCCGTTGCAAATACTGTAGTCAGTTTTTCGACAGCAAAGAAACGCTGAACGTTCACCTCGACAATGAGCACGGCTCCGCGAGTCTGAGTCGAAATAGGTCTCCGAATGCCGCGGTCAAACAAGAATCGTCTCAGCAGCTGGACCAATCCGAGAATCCCGTTAATTTGCTTAGCGTGAAGGACTTCGCGATAAATTGGCTAGCCAGCGGGCAACACGTGCAATCGCACAACGCACAAATGCAGACGCAGAACGAGGAATCCTGGATGCCAGGATCGGTCAATCATATCCCACCGTTGCCCAACCACTTGCAAATCCTTTCTGGCTTTCCCGGCGCGTTGGCGCAATATTTGCCAATGCCCGCGTTCCCGTTAACAGATTCCGGCTCGATGGTGAAACCGTCGTTAGGACCAACGCCGGTCAGGATCTTCAATCCGGAAGCGTACTGTGATCTGTGCAATAAAGAATTCTGCAACAAGTATTTCCTCAAGACGCACAAAGCGAACAAGCACGGCATCTACGCCGATTCGCCGGGACCTAGCACCGTGGACAATAGCATTCCAGGACCATTGTTTCCTGCCAACTATTCTAGTAACGTGATTAAGCTGGAACTACCCCCTACGCCACCTACGCCGACCGTCGCGTGTGATCTTTGTCAGAAGCGTTTCAAGAACGAGGAATCGATGCGTAAACACAAGCAAAAGATGCACATCGAGCTGCTGGATCAGTCGCAGGAGTCGCAGTCCGTTGTAAATCTGTTGCAAAACGAGGAGGACAGGGACACCCCGAGGGACAGTCTCGGTGGTATGGAGACGTTGTTTAAACAAGAGTACGGGACACTGGAGCAGGAGGACGCGACGTTCGTACCAGCGCCCAGGCATCTATCGCCTCAATCGATTCAGCAGGCACGGGACTCGGGTTTCAGCGCCGATCGGCTTCGTCGTTTGGGTGTCATAAACCCGGAGGCGTTCTGCGAGATATGCTGCAAAGAGTATTGCAACAAGTACTTCCTGCGTACGCACAAAATGAAGAGGCACGGCATCGTCGTTCACGACAACGAGAGATCGCCCGGCAGTCAAGGAACGGCGCCCAGCTGGCATCAAGTGCAGACCAGCCCGTTGAATCTGATCGTGACGGAGTCGAATTCTGGTAGCACGGagtcgaacgaacgagcaacCGGCGACGACTACGAGTGCAAATCGTGCGGGATACGTTTCCAGACGATTGGCCTGTATCAGGCACACTGTCGGAAGATGCACGAGAGCGAGGAGCAGCAGTCGCCCAGACCAGACTGCGAGTTGGACGCGGCCGATCAACGAAACGATTCCATCTCGGAGGATCTTCAGAAATTGCAGACGATGCTGTTGCAGTTGAACGGGCTTAAATCTAGCAAGGGGTTATCGTGCAACGTGTGCGGAAAAGAATTCGAGACCAGAGCTGCGTTGCATATTCATACGATAACGGAGCACGGAGCCAGCCAAGAAGATTCGACGTCCTCGCCGCAAGAAAAATCACCGTTAACCACGACCGTCGCCTACTGCGCCCTGTGCGGCAAGGATTACGCGAGCCAAGACGCTCTCAGGAAGCACATCGCCGACGAACATCAACCACCGATTTCGAATGCCACTCTTCCTCACACTCCCACGGCGACAACGACCAACACGAGTTCGACGAGCCAGACTCCGACGGAGAGGAAAGTCACGTCGATGACGCCCACGTCCAGCTACTGCGAGATATGCAACAAGGAGTTGTGCAATAAGTACTTCATGAAGACGCACATGCAAAGAATGCACGGCATCGAGATCGAGAACGGAGCCCAGATCGGAGGCGTGATATGCAACATTTGCAACAAGGAGCTGTGCAGCAAGTACTTTCTCCGCGTTCACAAGCACAACACTCACGGCATAGTCAATGAAAACACTGCCAGTTCGGTGAAACAAGAGGCTCACGAAACAACGAGCGCGGACGATGTCGCTTTGAAGCCGGAACAGCTCGGTGATCTGAGCCACAGATACTTTACTCACTTCACAGAGGTTTGTCCGATCTGCAGCAGGAGGTTCCGTAGTATAAAGTGGCTAAAGGCACACCTGATGGGTGATCACGGGAAAACAGGTGTCGATAAATGGCGCGAAATGGAGCAACAGTATCAAACGATGCCAAAATCAGGGAACAGAGCAGTAAACGTGGCGTCGAAGAGTGCTCAACAGAGCTCGAACCTGAAGATACCGAATGGATTTGAAATGTCGCAACAGATCAAGTCCACCGACTACGCTGGCTTGGGTAATCAAGTTCTGTCGAATTTACTAGGGTCGTCTACCGAAGATCAGCAGCTGAAAAGCTATCGTTGCTCCTATTGCAATTTCACGACTACCGTGCTGCCGTTCCTCTTTCTTCACGAAAGGTCTCACGTGATTTCGCACGACAACACGGAAGGAGAAAAATCGCTGCAGTGCCCGATCTGCTCGCAAGCTTTTCATCAGCCGGAGATGCTGCATCAGCATCTACTCGCGTCGCACCAGTTCCCCACTTTACTGCCCCATTTTCAACCCCCtgtgtttaataatttaagcCTGGACGCGGAGAAGTTGAACGAAGCCAAAGAGAAACTCGAGATGGAAGCAAAGGAGGATCGCACCGAGAACAGTTCGCAAGCGATTGCCAGTCAACATATTCCCGATCCGACGAGAAACAAACGACAGGATGAAACGGCGGTGCAAGTCACGCCTCACGGTGTGTACAAATGCGCGCAGTGCGGCTACGCGACGACCAATTTGAACAGGATCAAAAAGCACGTGAGGAAGGATCACAGAACGATCAGCGATCCTACCGACAGCGTGCTCGCCGAGCTCAGCAGAACTCTGAAAGACGTTGCCAATAAGCACAAGGTGCCAGCTTGCTACGCGACGCCGCAGGACATGAATTCGAATCCTGACAAGACGATCATGCAGCCGTTTCTCATCGAGGAACAGGACACGATGCAAGCTGGAGAGGAGTCCAGCTCGGAGAGGCGATTCGCGCCGGCTTTGGTCTACTTGCCGGTTAAGTCGAGAATCAACAACGCGTTCACCGCGTCCTTCACCCTCAGTCCCGCTTGA
Protein Sequence
MSSTMAHETTISELTELDSDGSSCGGERDARKRLRFDVDSTGPKKRRKQTTPVRFSSTLVPGAHEESNEDEDEDEEDSEGKLSLQSPVPCQSSIRDENLNNEFRCKYCSQFFDSKETLNVHLDNEHGSASLSRNRSPNAAVKQESSQQLDQSENPVNLLSVKDFAINWLASGQHVQSHNAQMQTQNEESWMPGSVNHIPPLPNHLQILSGFPGALAQYLPMPAFPLTDSGSMVKPSLGPTPVRIFNPEAYCDLCNKEFCNKYFLKTHKANKHGIYADSPGPSTVDNSIPGPLFPANYSSNVIKLELPPTPPTPTVACDLCQKRFKNEESMRKHKQKMHIELLDQSQESQSVVNLLQNEEDRDTPRDSLGGMETLFKQEYGTLEQEDATFVPAPRHLSPQSIQQARDSGFSADRLRRLGVINPEAFCEICCKEYCNKYFLRTHKMKRHGIVVHDNERSPGSQGTAPSWHQVQTSPLNLIVTESNSGSTESNERATGDDYECKSCGIRFQTIGLYQAHCRKMHESEEQQSPRPDCELDAADQRNDSISEDLQKLQTMLLQLNGLKSSKGLSCNVCGKEFETRAALHIHTITEHGASQEDSTSSPQEKSPLTTTVAYCALCGKDYASQDALRKHIADEHQPPISNATLPHTPTATTTNTSSTSQTPTERKVTSMTPTSSYCEICNKELCNKYFMKTHMQRMHGIEIENGAQIGGVICNICNKELCSKYFLRVHKHNTHGIVNENTASSVKQEAHETTSADDVALKPEQLGDLSHRYFTHFTEVCPICSRRFRSIKWLKAHLMGDHGKTGVDKWREMEQQYQTMPKSGNRAVNVASKSAQQSSNLKIPNGFEMSQQIKSTDYAGLGNQVLSNLLGSSTEDQQLKSYRCSYCNFTTTVLPFLFLHERSHVISHDNTEGEKSLQCPICSQAFHQPEMLHQHLLASHQFPTLLPHFQPPVFNNLSLDAEKLNEAKEKLEMEAKEDRTENSSQAIASQHIPDPTRNKRQDETAVQVTPHGVYKCAQCGYATTNLNRIKKHVRKDHRTISDPTDSVLAELSRTLKDVANKHKVPACYATPQDMNSNPDKTIMQPFLIEEQDTMQAGEESSSERRFAPALVYLPVKSRINNAFTASFTLSPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00224784;
90% Identity
iTF_01417927;
80% Identity
-