Basic Information

Insect: Melipona beecheii
Gene Symbol: FOXP1
Assembly: GCA_032399605.1
Location: JAUCMO010000053.1:2145207-2166058[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3.6 2.8e+03 -1.4 0.5 23 61 217 255 206 267 0.75

2 3 1.9e-29 1.5e-26 92.4 0.4 2 82 660 734 659 735 0.96

3 3 1.3e-05 0.011 16.0 0.0 49 82 734 762 733 767 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3.6	2.8e+03	-1.4	0.5	23	61	217	255	206	267	0.75
2	3	1.9e-29	1.5e-26	92.4	0.4	2	82	660	734	659	735	0.96
3	3	1.3e-05	0.011	16.0	0.0	49	82	734	762	733	767	0.87

Sequence Information

Coding Sequence: ATGTTCCCGAAGCCAGCCAATAACGGCGTAGGATACCAAGACGTCTCGGGCGCTCGAACACCATTAGATAAGATCAATATTGCTCAAAACACGGCTACTTCGCTGTTTGCAGCCCTgaagcagcagcaacagcaacagcaaccgCGCGACAGTGTTCCCTCGTCGAGGGAACGTGAGAACCGAGAACGAGATCGGTTGTCGGTCCGTGGCCGTGAGAACAACCGGAACGAGATAGGTAGCGGGGTGGCAGAGCAAtcgcagcaacagcagcaatcgcagcagcagcaacagcaacagcaacaacaccagcaacagcaacaacaacagcaacaggaGCTCACGATCGAGTATCAGAGCAATGGAAAGCTCAGTCCCGCTGGGCACGCAGTGACAGCAGCACCCATGACCCAGCAAAAGCAGCCAATTATCACGCAGCAGTCGCAACAGCCGAGCTCGGGGGCGCCTGGTCCCCAACCGAGTCCTCATCAGAGTCCGCAGGCCCCTCAGAGGGGTTCGCCGCCGAATCCTTCGCAAGGCCCTCCACCGGGGGGACCGCCAGGGGCACCACCCTCGCAAAATCCCTCGCAGATGATGCTCAACCCGGCTAGCGGCATCCATCAGATGCAACAGCTACTCCAACAGCACATACTCAGTCCTACCCAACTGCAGTCATTCATGCAGCAACACTCGCTCTATctgcagcaacagcaacagcaacaccATCAGGACTCAACGTCGGAGCATGCGTCCAATCAGGAACGATTCGGCTACTTTTCGTCTCTAAAGGACCATCAACACCAGTTCGCGGAACTGGGCAGGAAGAAGCTGGAGCAGGCGATTCAGCAACTGCAAGAACAGTTGCAACTCAATGTCATTCAGCAGACGCATCTTCTGCAAACGGCGGACAAGAAGAAGGCGTCCGCCCCGCTTCAGCAATTGGCGCTCCAGCAGCAACGCCTGATACAACAGCTGCAGATCACGCAGAGCCAATACCTTCTTCAACAGGGTCTGGGTCTTCAGGGTCACAATCCCTCTTCAGGTCTCCAACCCGGCGAAGGTCTACCAATATGGAAATCGGAAACGTCGGACGGTCCGGAATCCCACCAGAACTCGAACGTTCCAAAACCCGTGGCCGGACTCAACGGACTTCTCAATTCGACAGTGTCGAGTCGGCGGTCGGAGATGAACGGAACCACTCCACTGGACGAGAAACCGCTGGACGTTTCCTCCAACGACAAGGTTCATCCCCTGTACGGTCATGGGGTCTGCAAGTGGCCGGGCTGTGAAGTTATTTGTGAAGACTATCAAGCATTCCTTAAGCACTTGAACACGGAGCACACGTTGGACGACCGATCGACGGCGCAGGCCAGGGTTCAGATGCAAGTGGTCTCGCAGCTGGAGATTCAGTTGCAGAAGGAACGGGACCGGTTAACCGCCATGATGCACCACCTGCACGTGGCGAAACAAATGGCTTCCCCGGAACCACCAAAGTCCTCCGAGTCATCGACGGGCTCGAGTATACCAAAGTTAAATCTGTCAACCGCGCTGATGAACCAACCACCACCGAACTTTGGCGTCTCGCAAGTGTCACCGGTGTCGATGTCCGCGTTGGTGTCGGCGGTCAGGTCGCCAGCAGGTGGACAATTGCCACCTTCCGCCGGCGGAGCACCGATGCCGCCTATTCCCAACATGTCGAACATGTCCGGAATGCCTCCGTTGCCGAACATGCCGGGCAGCATGTCCACGATGCCGACCATGCCGAGCATGGCAGGGCCCATCAGACGACGTATCAGTGACAAATCCGCGCTTTCTCTGGCAGGAGGACTGTATGACGAGGGCACTGTAAGGCGCAGAGTAGCCGTCGATAGATCTGGAATAGATATTAACGAAGGGCTGCCCTACATGCTGGAGCGTGCTGGCCTTGACGTCCAACAAGaaattcaacgaaacagGGAATTTTATAAGAACGCCGACGTCAGACCGCCGTTCACGTATGCATCGTTAATCCGACAGTCGATCATCGAGTCGCCGGAGAAACAACTGACGCTGAACGAGATCTACAACTGGTTCCAGAACACATTCTGCTACTTCCGGCGCAACGCAGCTACGTGGAAGaACGCAGTGCGACACAACCTGTCTCTCCACAAATGTTTCATGCGAGTCGAAAACGTGAAAGGCGCCGTATGGACGGTGGACGAAAACGCGATCCGCACCAATCTATCATTGCACAAGTGTTTTGTGCGCTATGAGGACGACTTCGGGTCATTCTGGATGGTGGACGACGCCGAGTTCGTAAAGCGGCGGCATCTGTCCCGCGGCCGCCCCAGGAAATATGACCCAACCCCATCACCCACTCCACCCCACCTCTCCGCACAGGGTGTCCCGTCGAAAAGTCCGACCCTAACGCATAGCCCGACCATGTACGGTGACGCATTAAACGCCAATCTCCAGTATTTCCAGGCGGCACTCGGGGACTCCAATATGGGATTTTTAAACAACTCGATGTgcacgtcgacgacgacgagccCCGACAAGGAGCACGTGCTAGCCCATAACGATTTAATGTCACCGTTGGATGAACCAGCCGTGCACATAAAGCAGGAGGGTCAGAGTCCAGAGGGGGGTAAACTCACGAGATTAATAAAACGGGAGCTGGTTGACGCGCCTGCGGAGCAAGAGGGTGAAGAGGATCAGGTGGACGAGAGGGAGTATCCGGAGAGTCACGGCCACGACTCCGGCCAGGACGAGGACATGGCCGAGGACCTGTCGATGGCGCCCGACATAATGACACCGGAGGATCAGATCGAGGCGTAG
Protein Sequence: MFPKPANNGVGYQDVSGARTPLDKINIAQNTATSLFAALKQQQQQQQPRDSVPSSRERENRERDRLSVRGRENNRNEIGSGVAEQSQQQQQSQQQQQQQQQHQQQQQQQQQELTIEYQSNGKLSPAGHAVTAAPMTQQKQPIITQQSQQPSSGAPGPQPSPHQSPQAPQRGSPPNPSQGPPPGGPPGAPPSQNPSQMMLNPASGIHQMQQLLQQHILSPTQLQSFMQQHSLYLQQQQQQHHQDSTSEHASNQERFGYFSSLKDHQHQFAELGRKKLEQAIQQLQEQLQLNVIQQTHLLQTADKKKASAPLQQLALQQQRLIQQLQITQSQYLLQQGLGLQGHNPSSGLQPGEGLPIWKSETSDGPESHQNSNVPKPVAGLNGLLNSTVSSRRSEMNGTTPLDEKPLDVSSNDKVHPLYGHGVCKWPGCEVICEDYQAFLKHLNTEHTLDDRSTAQARVQMQVVSQLEIQLQKERDRLTAMMHHLHVAKQMASPEPPKSSESSTGSSIPKLNLSTALMNQPPPNFGVSQVSPVSMSALVSAVRSPAGGQLPPSAGGAPMPPIPNMSNMSGMPPLPNMPGSMSTMPTMPSMAGPIRRRISDKSALSLAGGLYDEGTVRRRVAVDRSGIDINEGLPYMLERAGLDVQQEIQRNREFYKNADVRPPFTYASLIRQSIIESPEKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENVKGAVWTVDENAIRTNLSLHKCFVRYEDDFGSFWMVDDAEFVKRRHLSRGRPRKYDPTPSPTPPHLSAQGVPSKSPTLTHSPTMYGDALNANLQYFQAALGDSNMGFLNNSMCTSTTTSPDKEHVLAHNDLMSPLDEPAVHIKQEGQSPEGGKLTRLIKRELVDAPAEQEGEEDQVDEREYPESHGHDSGQDEDMAEDLSMAPDIMTPEDQIEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01411297;
90% Identity: iTF_00222355;
80% Identity: -