Basic Information

Insect: Melinopterus prodromus
Gene Symbol: topi_1
Assembly: GCA_964023965.1
Location: OZ030391.1:89733396-89744506[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0015 0.15 14.2 1.3 3 21 120 138 118 139 0.93

2 13 1e-06 0.0001 24.2 0.9 1 23 164 186 164 186 0.97

3 13 0.016 1.6 11.0 2.0 2 23 193 214 193 214 0.95

4 13 0.59 59 6.0 0.1 2 19 233 250 232 252 0.94

5 13 9.3e-05 0.0093 18.0 0.7 2 23 307 328 306 328 0.97

6 13 2 2e+02 4.4 3.5 2 20 371 389 370 394 0.82

7 13 2.2 2.2e+02 4.2 0.1 1 23 519 542 519 542 0.95

8 13 0.0053 0.53 12.5 0.2 1 23 546 568 546 568 0.97

9 13 2.3e-05 0.0023 19.9 5.4 1 23 574 596 574 596 0.98

10 13 0.046 4.6 9.5 0.2 1 23 602 627 602 627 0.96

11 13 0.23 23 7.3 2.9 1 23 633 655 633 655 0.86

12 13 3e-05 0.003 19.5 0.5 3 23 663 683 661 683 0.98

13 13 7.5e-06 0.00075 21.4 0.7 1 23 689 712 689 712 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0015	0.15	14.2	1.3	3	21	120	138	118	139	0.93
2	13	1e-06	0.0001	24.2	0.9	1	23	164	186	164	186	0.97
3	13	0.016	1.6	11.0	2.0	2	23	193	214	193	214	0.95
4	13	0.59	59	6.0	0.1	2	19	233	250	232	252	0.94
5	13	9.3e-05	0.0093	18.0	0.7	2	23	307	328	306	328	0.97
6	13	2	2e+02	4.4	3.5	2	20	371	389	370	394	0.82
7	13	2.2	2.2e+02	4.2	0.1	1	23	519	542	519	542	0.95
8	13	0.0053	0.53	12.5	0.2	1	23	546	568	546	568	0.97
9	13	2.3e-05	0.0023	19.9	5.4	1	23	574	596	574	596	0.98
10	13	0.046	4.6	9.5	0.2	1	23	602	627	602	627	0.96
11	13	0.23	23	7.3	2.9	1	23	633	655	633	655	0.86
12	13	3e-05	0.003	19.5	0.5	3	23	663	683	661	683	0.98
13	13	7.5e-06	0.00075	21.4	0.7	1	23	689	712	689	712	0.98

Sequence Information

Coding Sequence: ATGAACACAGCGCCAGATATAACTTTTATCCGGGTGCATTTCCTAACAACAGAAGGACCCACCACAGCGATACAATACGAGGTAGACAATTCCTCGCAAGAATTCATCATGAAAACAGCAGTGCCGGCTAATACAAACCAGGAATTTAACACGGGAGAGAACGATAAGCTTAAGTTTAAACACCCTGTCGTAGAAATTGATAATTCGTCCATACGGGTGATACGCATTGGGGGTGTCGAAGATCTAAACCCTCAAAATTACGCAGAGGAAACTGACGGTGAGTCTAAACCGTTGATATCCGTTAATCTCCAGCCGAAACGAGACTTTAAAATCCCAAATATCCCTACGATGATTATCTGCCAGAATTGTGATACGAATTTCCCGACTAAATACCAATATCAGCGGCACCAGTGCGAGTTTAACGCtgaaaaagttgttttaaagcCAAATATCGATATTAAAGACATCGACAAGAGTATGCGGATGAAATTTGACTGTCCGACGTGCGGAAAACAATTCGTGAGCAAGAATAATCTAGAACGGCATCAGACGAGTCACGACGAAACTAACATCAACGTTTGCGAGCACTGCAACAAACAATTCGTATCGGAAAATCGTTTACGAATTCACAAGGAGAACCACTGTAAGAAAGCCggtgatatttctaagttttatcgTAGCGATGTCACAGTTTGGAAGTGCGTTAATTGTTATCAGGTTTTTGCGACACCTACCTCGGCGAATAAGCACTCGGAGTTGTGCGTGGAGAATTTGAATGTGTCGAAAAATGTTGAGGAGTTGAACGAAGAGTTGAAGAATTTGGCGCAAGTTGTGCCGGAGCTGTTGGAATCTAGTAGCAGTAAGTTGGACGCCGTTTCGAGCAAAAACGTGCAGAAGTTCTTGACGGAGCTGTTGCTGCAGTGCGAGTATTGCAATCGGACTTATGCTGATAAGAAGTGGCTGTTGGAGCACCAGAAGCAGCACACTACGGAGGTGAACTACGAGTGCATTACGTGTAACGAGGTGTTCGATTCGTATATCTCGGCTTCGAAGCACTGGCTAACGAAATGCTCCGACGAAGCGAACCTATTCTACCTCCCGAAGCTGACCTACTGCGAATTCTGCGACCGAACATTCAAATCGCACGAGATCCTCTACACGCACAAATTCAAGAAGAAGCACTACACTCCGAAGGTCTACAACTCGGCCAGCAGCGCGGCCGTCTCCAAGAACCGTCAAAATCCGAAAGAGAACGGCCTGAGAATCGTCGAAAACAAAGAGGCGATCGTCAAACTGATCGAAGACGTCCTATGCTCGATGAATTCGAACGAAGAGGACAAGGAGAACGACGACACGAACAGCGGACGCGAGACGGGCGACGGAAGTTGCACTGACGTCGTCATCAAGTCGGAAATATGCAGCGAGTCGAGCAGCATGAGCAAGTCTGACGTTTCGCAGGACGGCGAGAAGAAGAAACGCGGTAGGAAGAGGAAAAGCCCGCGCCAGACTAGCAAGAGTAAGCGGCTGAACGCGGTCGTCGAAGACGGGTTTAAGTATCAATGCGAGAGGTGCGTCACCGTCTGGGATAGCGTCGCCGATCTGGAGAACCACAGGGAGACTCAGCATCCGGCCAAGTTCAAGTGCGAGGAGTGTGGACAGgtTGTTCACAGCGCTAAGGCTCTTCTGATCCACAGCAGGGCCCACCAGAGTTTGAAGCCTTACGTCTGCGAGATCTGCAAACGTTGTTACTCGCAAACTTCCCACCTGTGGCAGCACATGCGTTTCCACCAAGgcATCAAGCCTTTTGCATGCCCGCATGAGGGTTGCGAGGCTCGTTACACAATTCGCCCCGACTTGAAGGACCACATAAGGAAGGTGCACACTAGGGAGCGCCCTTTCAAATGTTCCGTCTGCGACAAGTGTTTCTTGACCGGCTCCGTTTACTACCAACATCGGCTGATTCACACCAATGATCGCAGATACGGATGTGACATCTGCCAGAAGCGTTTTTTTAGAGCTGACGCGTTGAACAACCATCGTAGAATTCATACGGACGAGCGCCCTTATCCTTGCGATATCTGCGGCAGGCAGTTCCGTCAGAAAGGAGACAGGAATAAGCATGTTCGCACCCAACACCCTTCCTAA
Protein Sequence: MNTAPDITFIRVHFLTTEGPTTAIQYEVDNSSQEFIMKTAVPANTNQEFNTGENDKLKFKHPVVEIDNSSIRVIRIGGVEDLNPQNYAEETDGESKPLISVNLQPKRDFKIPNIPTMIICQNCDTNFPTKYQYQRHQCEFNAEKVVLKPNIDIKDIDKSMRMKFDCPTCGKQFVSKNNLERHQTSHDETNINVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCVNCYQVFATPTSANKHSELCVENLNVSKNVEELNEELKNLAQVVPELLESSSSKLDAVSSKNVQKFLTELLLQCEYCNRTYADKKWLLEHQKQHTTEVNYECITCNEVFDSYISASKHWLTKCSDEANLFYLPKLTYCEFCDRTFKSHEILYTHKFKKKHYTPKVYNSASSAAVSKNRQNPKENGLRIVENKEAIVKLIEDVLCSMNSNEEDKENDDTNSGRETGDGSCTDVVIKSEICSESSSMSKSDVSQDGEKKKRGRKRKSPRQTSKSKRLNAVVEDGFKYQCERCVTVWDSVADLENHRETQHPAKFKCEECGQVVHSAKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYGCDICQKRFFRADALNNHRRIHTDERPYPCDICGRQFRQKGDRNKHVRTQHPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00137296; iTF_00138420;
90% Identity: iTF_00138420;
80% Identity: -