Basic Information

Insect: Aphodius granarius
Gene Symbol: topi
Assembly: GCA_963971325.1
Location: OZ020222.1:40236874-40242953[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00097 0.083 14.2 1.3 3 21 120 138 118 139 0.93

2 14 6.4e-07 5.5e-05 24.2 0.9 1 23 164 186 164 186 0.97

3 14 0.0097 0.83 11.1 2.0 2 23 193 214 193 214 0.95

4 14 0.37 32 6.1 0.1 2 19 233 250 232 252 0.94

5 14 5.8e-05 0.005 18.1 0.7 2 23 292 313 291 313 0.97

6 14 7.1 6.1e+02 2.0 0.1 1 21 319 339 319 340 0.85

7 14 1.2 1.1e+02 4.4 3.5 2 20 356 374 355 379 0.82

8 14 1.4 1.2e+02 4.3 0.1 1 23 499 522 499 522 0.95

9 14 0.0033 0.29 12.5 0.2 1 23 526 548 526 548 0.97

10 14 1.4e-05 0.0012 20.0 5.4 1 23 554 576 554 576 0.98

11 14 0.029 2.5 9.6 0.2 1 23 582 607 582 607 0.96

12 14 0.14 12 7.4 2.9 1 23 613 635 613 635 0.86

13 14 1.9e-05 0.0016 19.6 0.5 3 23 643 663 641 663 0.98

14 14 4.7e-06 0.0004 21.5 0.7 1 23 669 692 669 692 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00097	0.083	14.2	1.3	3	21	120	138	118	139	0.93
2	14	6.4e-07	5.5e-05	24.2	0.9	1	23	164	186	164	186	0.97
3	14	0.0097	0.83	11.1	2.0	2	23	193	214	193	214	0.95
4	14	0.37	32	6.1	0.1	2	19	233	250	232	252	0.94
5	14	5.8e-05	0.005	18.1	0.7	2	23	292	313	291	313	0.97
6	14	7.1	6.1e+02	2.0	0.1	1	21	319	339	319	340	0.85
7	14	1.2	1.1e+02	4.4	3.5	2	20	356	374	355	379	0.82
8	14	1.4	1.2e+02	4.3	0.1	1	23	499	522	499	522	0.95
9	14	0.0033	0.29	12.5	0.2	1	23	526	548	526	548	0.97
10	14	1.4e-05	0.0012	20.0	5.4	1	23	554	576	554	576	0.98
11	14	0.029	2.5	9.6	0.2	1	23	582	607	582	607	0.96
12	14	0.14	12	7.4	2.9	1	23	613	635	613	635	0.86
13	14	1.9e-05	0.0016	19.6	0.5	3	23	643	663	641	663	0.98
14	14	4.7e-06	0.0004	21.5	0.7	1	23	669	692	669	692	0.98

Sequence Information

Coding Sequence: ATGAACACAACACCGGATCTAACATTTCTCAGGGTACATTATGTTCATTCTGAAGGCCCCATGAGCTCTATACAGTACGAGGTCGACAATACCTCGCAAGAATTCGTCATGAAAACCGCCGTTCCGGCTAACATAAACAGGGATTTTACCGTGGGGGAGAACGACAAACTACGGTTTAAAAAGGCAGGCGTTGCAGAGATCGATAACGCCATTCGAGTTCTACGCATCGGGGGCCTCGACGACACGGGCAATTTTCCCGAAGAAAACGACGGCGAATACAAACCCACAATTACGAATAACGGGGTTAATCATCAGAAAAGAGAGTTTAAAATACCAAATATTCCTACGATGATAATCTGTCAGAACTGCGATACAAATTTCCCAACTAAATATCAATATCAGCGTCACCAGTGCGAATTTAATGCCGAGAAAGTGGTTTTGAAGCCGAATATCGACCTGAAAGACATCGATAAGAGCATGCGGATGAAATTCGATTGCCCGACTTGCGGCAAGCAATTTGTGAGCAAAAATAACCTAGAACGTCACCAAACGAGTCACGACGAAACAAACATAAACGTTTGCGAGCACTGCAATAAACAGTTCGTCTCCGAGAATCGTTTACGTATCCACAAAGAGAACCATTGCAAGAAAGCGGGGGATATTTCCAAGTTTTATCGTAGCGACGTAACCGTGTGGAAATGTGTGAACTGTTATCAAGTTTTTGCGACGCCGACGTCCGCTAATAAACATTCGGAGGGCTGCTCGGAAAATTTGAGTAAGAACGACGAGGAATTGGCCCCGGAGGAGGTCAATAATTCGTCGACGGAAGCGTCGAGTCGTAACGTACAAAAATTCTTGACGGAGTTACTGCTTCAATGCGAATATTGCAATAGGACGTATGCGGATAAAAAATGGCTCTTGGAACACCAGAAACAGCACACGACGGACGTCAATTACGAGTGTATTACTTGCAATGAGGTTTTCGATTCGTATATTTCGGCTTCGAAGCATTGGTTGACTAAATGTTCGGACGAAGCGAACCTATTCTACCTGCCGAAACTCACGTACTGCGAATTCTGCGACCGCACCTTCAAATCGCACGAGATCCTCTACACTCACAAGTTCAAGAAGAAGCATTACACCCCGAAAGTGTACAATTCGAACGCGAAAAACCGTTTGAACCCGAAAGAAAACGGTTTGCGTATCGTCGAGAATaaagaagcgattgtaaaattaATCGAGGACGTCCTGTGCTCGATGAATTCGAACGACGACGATAAAGAGAACGAAGATACGAACAGCGGTAGGGATACGGGCGAGGGAAGTTGCACGGATATCGTTATCAAGTCGGAAGTTTGTAGCGAATCGAGTAGTATGAGTAAATCTGATGTGTCGCAAGATGGGGAGAAGAAAAAGAGGGGTAGGAAGAGGAAGAGTCCCCGGCAGACTAGTAAGAGTAAGAGGTTGAATGCTGTTGTCGATGATGGGTTTAAGTATCAGTGCGAACGGTGTGTGACCGTTTGGGATAGCGTAGCCGATCTGGAGAATCATCGGGAGACGCAGCATCCTGCCAAGTTTAAGTGTGAGGAGTGTGGACAGGTTGTCCACAGTGCGAAGGCCCTTCTGATCCACAGCAGGGCCCACCAGAGTTTGAAGCCGTACGTCTGCGAGATCTGCAAACGTTGCTATTCGCAAACTTCCCATCTGTGGCAGCACATGCGCTTCCATCAAGGTATAAAGCCGTTTGCTTGTCCCCATGAGGGCTGCGAAGCCCGTTACACCATCCGTCCGGATTTGAAGGACCACATTCGGAAAGTCCACACCAGAGAGCGCCCTTTCAAGTGCTCCGTCTGCGATAAGTGCTTCCTAACTGGCTCTGTTTATTACCAGCATCGATTAATACACACCAACGACCGCAGATATGGATGCGATATCTGTCAGAAGAGATTTTTTAGAGCGGACGCGTTGAATAATCATCGAAGAATTCATACGGATGAAAGGCCGTATCCTTGCGATATCTGCGGAAGGCAGTTCCGCCAGAAGGGCGACAGGAATAAGCACGTTCGCACCCAACATCCTTCCTAA
Protein Sequence: MNTTPDLTFLRVHYVHSEGPMSSIQYEVDNTSQEFVMKTAVPANINRDFTVGENDKLRFKKAGVAEIDNAIRVLRIGGLDDTGNFPEENDGEYKPTITNNGVNHQKREFKIPNIPTMIICQNCDTNFPTKYQYQRHQCEFNAEKVVLKPNIDLKDIDKSMRMKFDCPTCGKQFVSKNNLERHQTSHDETNINVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCVNCYQVFATPTSANKHSEGCSENLSKNDEELAPEEVNNSSTEASSRNVQKFLTELLLQCEYCNRTYADKKWLLEHQKQHTTDVNYECITCNEVFDSYISASKHWLTKCSDEANLFYLPKLTYCEFCDRTFKSHEILYTHKFKKKHYTPKVYNSNAKNRLNPKENGLRIVENKEAIVKLIEDVLCSMNSNDDDKENEDTNSGRDTGEGSCTDIVIKSEVCSESSSMSKSDVSQDGEKKKRGRKRKSPRQTSKSKRLNAVVDDGFKYQCERCVTVWDSVADLENHRETQHPAKFKCEECGQVVHSAKALLIHSRAHQSLKPYVCEICKRCYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCSVCDKCFLTGSVYYQHRLIHTNDRRYGCDICQKRFFRADALNNHRRIHTDERPYPCDICGRQFRQKGDRNKHVRTQHPS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00981516;
90% Identity: -
80% Identity: -