Mpro029833.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melinopterus prodromus
Gene Symbol
-
Assembly
GCA_964023965.1
Location
OZ030393.1:44888556-44896491[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0012 0.12 14.5 0.9 1 23 288 310 288 310 0.94
2 12 0.11 11 8.4 2.6 2 23 401 423 400 423 0.92
3 12 0.00017 0.017 17.2 2.5 1 23 429 451 429 451 0.98
4 12 5.3e-05 0.0053 18.8 0.6 1 23 456 479 456 479 0.91
5 12 2.9e-05 0.0029 19.6 4.7 1 23 485 507 485 507 0.98
6 12 2.9e-05 0.0029 19.6 1.2 1 23 513 535 513 535 0.93
7 12 0.0052 0.52 12.5 2.9 1 23 541 563 541 563 0.98
8 12 1.5e-06 0.00015 23.6 0.6 1 23 569 591 569 591 0.98
9 12 6.9e-06 0.00069 21.6 4.7 1 23 597 619 597 619 0.98
10 12 0.00056 0.056 15.6 4.7 2 23 626 647 625 647 0.97
11 12 0.0003 0.03 16.4 1.0 1 23 653 675 653 675 0.98
12 12 1.8e-06 0.00018 23.4 1.0 1 23 681 703 681 703 0.98

Sequence Information

Coding Sequence
ATGGAGGTTACTACTTTGTTATGTGACTCATCGTATTGTCGATTGTGCGGCCAAGAAAACGATAAATCCACCAGCCTTTTTGAGTTGCAGGAAAACAAACATTATTTAAGCGATTTGGTGAACCGATATTTACCGCTCAAGGTTACAGACGATCGTAAGTTTCCAACTAAAATATGCCCAGGATGCATATTTCAATTAGAAGCAACAAAATCGTTTTTGGATTTGGTAATCAAAGGACAAAGTACGCTTAGAGAGTTACACGCAAAGcaacaagaaacattaaaacgGCAGGAGAAACAACGGCAGCAATTGGAAAGTGCTTTAAAGTTAGTAAATCCCTCCTCTAGCATAGGCGCTTACAGTATACAGGAAGACGAAGTTGGCGAGAAGATATTAATACAAATTTTATCGGATGGTCCCTTATTCTCCCCCGATCACGAGTTATCCCTGAAAGGCGAGGGCCTTGAAAAGCCGAGACGGAAGAGAGGTCGACCACCAAAACCGTACGTTTCAGAGGACAATAAAGAAAACGATAACCTCAAAGATGATCAAGACGAAGAAACGGATATCGATGGAGACAGTCGAAGGAGAAGAAGAATTAAAGTTCCCTCACGTTTGCAAGAAACATTACAAGGTAAAGAAATGGACCGCATTTTCAAGCAAGAAGGTCTCATAGAAGATGATTCACTCTCAGACGCTGATGACCCATTGGCTATTGAACATGACAAAAGCGTTAATGAAATCATCGGACATATGGAAGATAAAGACGGGGAGGACATGGGAGAATTAGTTGTGATAAACAAAACgacaaacaaaatcaaaatacgACCGAAAGGGAATAATACTAAACGGAAGAGGAGGTTTGAGTGCGATATCTGCAGCCGGGTATTTTCGCATGCAGGGAGGTTAGAAGTGCATAAATCGTTCCACAGAAATGTGAACTATATGTGTGGGACAGAAGGGTGCGGTATGCAAACTGATTCGAAGGAAGGTGTCGAGGAGCATCACAATGAGACCGGGCATTCTGGTGTTACGTTACTCGAAACTATCGATTTCGAGATTTCCGGAGAGgCCAAGGACAAGGGTGACCAGGACCTGTTAGAAAGTGCCCAGATTTCTATAAATACGCTAGAGGCTGAAGATGTGCCACTACCCGAAGAACCAATCGTCCAACCGGCCCCTGTGAAAGAGGAACGTACAACCTGCAAACTGTGCAAGAAAACCTTCTCATGCAAGCAGAACTACGCTGTCCACGTTAACGCCGTCCACAAGCGTCAGAAACCTTACAAATGTGAGAAATGCGACAAAACTTTCCCGTACATCTCCAGCTATAAGTACCATCTGCAACAGCACACAGAAAAATTATTCCCGTGTGATATCTGCGATAAAGTTTTTAACCACTCCAGTAGTCTCGTCTACCATAAAGAGGCCGAACATAATAACGGACGACGATTCGTCTGCAGTAAATGTAAGAAGACTTTCAAGCATAAACAGTTGCTCTTGAGGCATCAGCTGGTGCATTCAAACCTACGACCTCACGTCTGCAAGTATTGCGATGCCAGTTTCAAGACCCGCGCAAACCTGCTGAACCACATGCCAACTCATACTGGCGAGCGGAAATACTATTGTAATTTGTGTCCGAACACGTTTGCGCACAAGACATCTCTGACCTTCCACATGCGGTGGCATAATGGGTCAAAACCGTATGAGTGTGATGTTTGTAGAAAGACTTTCTCCCAGAAGGGAAACCTGGCTGAGCATAAAAGGATTCACACAGGAGAAAAGCCATTCACATGTAATCAGTGTGATAGAAAATTCACCACTTCATCACAATACAAGAACCACCTAAAACGTCATACGGGTGAACGACCCTGGCAGTGCGAGTATTGCTCGAAGACTTTCTTCCATAAAGATACATGGAAGTCGCACACAAGACGCCACAGTAACGAGCGACCATTCCAGTGTAATCAGtgTATGAGAGCGTTTACGGAGCAATGGGCACTAAAGAAGCACCAGCGTCTGCACACCGGCGAAAAACCATACGTGTGTGAATTCTGCAATAAGAAGTTTGCCGACTCTTCAAATTTGGCAAAGCACAAGAAGATCCACATAAGCAAGCTTAACCAATCGGAGAAGAATGGCGCAAACATCAAAATTATCACGTCCGATCAAGGCGACAAGATTTTGTACTTGACATATGACGATGGAACGAATGATGACGATGAGCCTCAGACCGTTGTACATATTATGGATTCGCTCGATGACATCCCTTCAGCTGTTAGTCAGGATACCGATGACGTCAGTATTATGACAACTGACGGAATTGTCGATGACGGTCCTGAAGATCTTACTTTGGATGCTTCTTTACAGTTGCAGCAAGTGATAGACAATGATGGAAATGCTGTAAACATCACAACAGAAAGCGGAGACGTAATAAAAGTTGTGATGAGCATACAGAACGGGGAGCAAGCAATACAAGGATTATTAAGTGACGGGACCTTAGTTCCTATTGATTTGGTAATGCAAGATGGAAAGCTGATGTCTGCGTCACTCTCGGGACCGATGAAGGAAGATCCGGACAAATATACGgatGATGATCCAACCAAAGAATTATCTATTCCGCCCATTGAATCGATGCTAGAGAGCAGCATGCAATTTTTATCGGAGGATGGGCAAAAGTTGGAAAACAGTATTCAATTTTTGTCTGAAGATGGGCAAAGCCTCTGCTTTGTGGCAACGTACAATTCAGACGATGTTGTTAACTCGGAATACATATGA
Protein Sequence
MEVTTLLCDSSYCRLCGQENDKSTSLFELQENKHYLSDLVNRYLPLKVTDDRKFPTKICPGCIFQLEATKSFLDLVIKGQSTLRELHAKQQETLKRQEKQRQQLESALKLVNPSSSIGAYSIQEDEVGEKILIQILSDGPLFSPDHELSLKGEGLEKPRRKRGRPPKPYVSEDNKENDNLKDDQDEETDIDGDSRRRRRIKVPSRLQETLQGKEMDRIFKQEGLIEDDSLSDADDPLAIEHDKSVNEIIGHMEDKDGEDMGELVVINKTTNKIKIRPKGNNTKRKRRFECDICSRVFSHAGRLEVHKSFHRNVNYMCGTEGCGMQTDSKEGVEEHHNETGHSGVTLLETIDFEISGEAKDKGDQDLLESAQISINTLEAEDVPLPEEPIVQPAPVKEERTTCKLCKKTFSCKQNYAVHVNAVHKRQKPYKCEKCDKTFPYISSYKYHLQQHTEKLFPCDICDKVFNHSSSLVYHKEAEHNNGRRFVCSKCKKTFKHKQLLLRHQLVHSNLRPHVCKYCDASFKTRANLLNHMPTHTGERKYYCNLCPNTFAHKTSLTFHMRWHNGSKPYECDVCRKTFSQKGNLAEHKRIHTGEKPFTCNQCDRKFTTSSQYKNHLKRHTGERPWQCEYCSKTFFHKDTWKSHTRRHSNERPFQCNQCMRAFTEQWALKKHQRLHTGEKPYVCEFCNKKFADSSNLAKHKKIHISKLNQSEKNGANIKIITSDQGDKILYLTYDDGTNDDDEPQTVVHIMDSLDDIPSAVSQDTDDVSIMTTDGIVDDGPEDLTLDASLQLQQVIDNDGNAVNITTESGDVIKVVMSIQNGEQAIQGLLSDGTLVPIDLVMQDGKLMSASLSGPMKEDPDKYTDDDPTKELSIPPIESMLESSMQFLSEDGQKLENSIQFLSEDGQSLCFVATYNSDDVVNSEYI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00137267;
90% Identity
-
80% Identity
-