Basic Information

Insect: Melinopterus prodromus
Gene Symbol: UBTF
Assembly: GCA_964023965.1
Location: OZ030399.1:6411548-6415939[-]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2.1e-21 4.5e-18 67.1 0.9 1 68 232 299 232 300 0.97

2 4 3.6e-06 0.0075 18.3 9.1 1 68 324 390 324 391 0.93

3 4 2.7e-06 0.0056 18.7 1.5 2 68 423 487 422 488 0.78

4 4 0.023 49 6.1 2.2 39 68 569 598 567 599 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2.1e-21	4.5e-18	67.1	0.9	1	68	232	299	232	300	0.97
2	4	3.6e-06	0.0075	18.3	9.1	1	68	324	390	324	391	0.93
3	4	2.7e-06	0.0056	18.7	1.5	2	68	423	487	422	488	0.78
4	4	0.023	49	6.1	2.2	39	68	569	598	567	599	0.90

Sequence Information

Coding Sequence: ATGGGACATAAGAGAACAAAGAAAGAGGCCAAGAGGCAGAACAGCAAAATTGAAGAGGAGGACGAAGAACAGCCCATGGAGCAACCCGTAGTGGAAAAGAAGCCGAAAAAATCAAAGAAGAAGAAACAGGCTAACGACGTAGAAGAGGCTACTGGCGAACCAGAGGTTGTCGCACCTACGACGCCGGCAAAAAAGGAACGCAAGAAGCGAGAAAAGAAGACAAAACACCACGCGGAAGTACCGGACGACAAACTCGAGGAACCGCATATCGACGAGAATAACATCGAAGAAGCCCACGAAATGAACGACAGCACGATGCTAGAAGAAGAACCCGAAACTGTCGGCAAGGTTCCCGGAAAAGTTGGCAGaccaaagaaaaacaacaacattgAAGAAGAAAAAATTATAGATTGGCCGGAGAAAGATCTATCCGAGCTGCTTAAACGGATTGAAGCAGCTATACCCGACAAGGATACATTAGCGTATAGCACGAGAGTTGAAAAGCTGAACTGGGATGACatcTCGTTCAAAAATTATACAGCCGAAGAGTGTAAGTCTATCTGGCAACTAGTGCAAAAGCGTCTCCGTAGGTTTAGATTATTAAGCGAACTTGTAACAGAGGCAAAGGAATGGATATCGAAGCCGTGGACCAACTTTTACAGCAGCCAGAAAAACAAACGTCATCCGGATATGCCAAGGAGGCCTTTGTCGATctatatgttgttttatgtgaaTAAACGTGACAAAATAATTGCGGAAAATCCTGGACTTGAAGTAACTGAGATCTCTAAAATAATAACCCAAATGTACAAAGCTCTGTCGCCGGcgaaaagagaaaaatatattaaagagGCAGCGGAAAAACGACGAATATACGAGACAGAATTGGAGGAATTTTATCGGCAACATCCGGAAATTTCAAGAACGATGGAGAAACAATCGCACGGGAAGCAATCAGGTGAACCAGGGCCAAAGAAACCGAATACGCCTTTCAACTTGTACTACGAGAGCCAGATAAAAGCTATGGATCAAACCGCATACGTAGATAAGCATACGTTCAAGGAACAATGCAAGGAGCAGTGGAAAAATATGTCCGAAAAGAAGAAGGTGGTATGGATCAATTGGGCTTCAGAAGAGGAAGCAAAATATCAAGACGAATTGAAGAATTACGTCTCGCAGAATCCGGACTTCGTCCCGTCAAACGTGAAACCAGTCCTAACCAAAGAAGAAAAATCAATAAAGGAGCGAATGGCGGGCAAACCGGTAAAACCACCAAATTCGGCGTATAGTTTATTCTCGAGAATGATGCTGCAAGGCGACGCAATTAAATACGTCACTCCCAAGGATCGGATGCAATACATTGCGGAGAAATGGAAAAATTGCACGGATGACGAGAGAAAAGTCTATAGCGAGCAAATTGTCCatTTACGGGAGCAGTACAAATTGGACTTTGCTTCCTACCTTGAATCTCTTCCTGAGGAGAAAAGGCAAGAGGAAATAAGGAATACTTTGCCAAAACGAAAGCGGAGCATATCAAAGAATGAGGACGCAGCGACGAAAAAGAAGAAGGGAGAGGAGGGCATCACCGAGAATAATAATAAGGTGAAGAAGGGCAAACAGGATGAGGAAGAAGCTGCGAAGAAGGAGGAGGATGATGAAAAGAAAAAGGACAAGAAAATAACGCCTTTTGCAAAACCGCCATATTGGAACCGAATGAAAAAAGAAGAGAAGCGGACGTTTAAGAATGCCATGCTAAAACTAAAGGAGCACTTAGACTCGAGATTTGAGAAATACATAAACGATCGTGAGGAAGAATCGTCCGAAGACGAATCCGAGGACTCGAACGAGTCAGCGTCGTCTTCCTCTGAGGAAGACAGCAGTTAG
Protein Sequence: MGHKRTKKEAKRQNSKIEEEDEEQPMEQPVVEKKPKKSKKKKQANDVEEATGEPEVVAPTTPAKKERKKREKKTKHHAEVPDDKLEEPHIDENNIEEAHEMNDSTMLEEEPETVGKVPGKVGRPKKNNNIEEEKIIDWPEKDLSELLKRIEAAIPDKDTLAYSTRVEKLNWDDISFKNYTAEECKSIWQLVQKRLRRFRLLSELVTEAKEWISKPWTNFYSSQKNKRHPDMPRRPLSIYMLFYVNKRDKIIAENPGLEVTEISKIITQMYKALSPAKREKYIKEAAEKRRIYETELEEFYRQHPEISRTMEKQSHGKQSGEPGPKKPNTPFNLYYESQIKAMDQTAYVDKHTFKEQCKEQWKNMSEKKKVVWINWASEEEAKYQDELKNYVSQNPDFVPSNVKPVLTKEEKSIKERMAGKPVKPPNSAYSLFSRMMLQGDAIKYVTPKDRMQYIAEKWKNCTDDERKVYSEQIVHLREQYKLDFASYLESLPEEKRQEEIRNTLPKRKRSISKNEDAATKKKKGEEGITENNNKVKKGKQDEEEAAKKEEDDEKKKDKKITPFAKPPYWNRMKKEEKRTFKNAMLKLKEHLDSRFEKYINDREEESSEDESEDSNESASSSSEEDSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00136842;
90% Identity: iTF_00137913;
80% Identity: -