Mvil094878.1
Basic Information
- Insect
- Melanotus villosus
- Gene Symbol
- Znf423
- Assembly
- GCA_963082815.1
- Location
- OY720427.1:41355300-41376174[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 22 3.8e-06 0.00085 22.1 0.5 1 23 58 80 58 80 0.97 2 22 0.093 21 8.2 3.3 3 23 88 108 86 108 0.97 3 22 7.4e-05 0.017 18.0 5.3 1 23 114 136 114 136 0.98 4 22 0.00026 0.058 16.3 0.2 1 23 142 164 142 164 0.98 5 22 0.00072 0.16 14.9 0.5 1 23 178 201 178 201 0.96 6 22 0.017 3.9 10.6 0.1 2 23 232 254 231 254 0.96 7 22 1.7 3.9e+02 4.3 0.1 1 20 296 315 296 316 0.93 8 22 0.012 2.7 11.0 0.0 1 23 413 435 413 435 0.97 9 22 0.00022 0.049 16.5 0.0 2 23 450 471 450 471 0.94 10 22 3 6.7e+02 3.5 1.5 3 23 481 503 479 503 0.82 11 22 0.079 18 8.5 2.8 1 23 508 531 508 531 0.96 12 22 0.025 5.7 10.0 1.9 2 23 596 618 595 618 0.96 13 22 0.39 88 6.3 0.4 1 23 677 700 677 701 0.94 14 22 0.00052 0.12 15.3 4.4 2 23 712 733 711 733 0.97 15 22 0.0016 0.36 13.8 0.3 1 23 742 764 742 764 0.97 16 22 0.58 1.3e+02 5.7 0.7 2 23 772 793 772 793 0.96 17 22 9.6 2.2e+03 1.9 0.1 1 13 839 851 839 855 0.85 18 22 0.13 30 7.8 0.3 1 23 902 924 902 924 0.94 19 22 0.095 21 8.2 0.8 1 23 932 954 932 954 0.95 20 22 0.0014 0.32 14.0 0.3 1 23 962 984 962 984 0.97 21 22 0.44 99 6.1 1.7 1 23 991 1013 991 1013 0.94 22 22 0.5 1.1e+02 5.9 0.4 2 21 1046 1064 1046 1065 0.86
Sequence Information
- Coding Sequence
- ATGGTATTTTTTCTTTCAGGATCAATTGGAACCGAACATGGAAGTTGGGGTTCTAACACTCCAGAACAAGCTTCTCCAGCACCAAGTTCTTGTCCAACACCGAGTTCCAGTTTAAGTGATATCGCGGAAGCAGAAATATCCTTCACTGTTGGGGTAACAGAAACCACCCCGTATGCTTGCAAAATTTGTAACAAGGCTTTCGCCAGGTCGTCCTTGCTGAGCAAACACGAACAGtCACATACGGATCAACTACAGTATGGATGCTCCTACTGTCCAAGGCTGTTTAAACACAAACGGTCACGTGACAGGCATATTAAATTACACACTGGGGATAAAAAGTATAAATGCATCCATTGCCAAACTGCATTTTCCAGGAGtgaCCACCTGAAAATTCATATGAAAACTCACGACAACAGCAAGCCCTTCCGCTGTTTGGTATGCAATCGTGGTTACAACACCGCAGCTGCTCTTACCTCCCATCAGCAGAGTCATGCTAAGCAAAATGCTGAAAACAGGCAAAGTCCAGGGAGTTTTCGATGCCTTCAGTGTCCGGAAATTTTCAGTAGATATGATTTACTACAGatacATACATCTTCCAACCACTCCTCAATCGCAGTTAACTCTTCGCAGCAAACCATACCTGTAACCATACAGGACAACAACATAAAAAGCCACATAGAATTACCAAAATGGGTTTGCATGTACTGCGGTAAAGACTTCCTAACACTTGATGAAATGCAGCAGCATGTAAATACAGATCACAATGCAATAGTAAATGGAAACTTTGTGAGTAGTCCTTGTAAAACTGCGGCTTCAGATGCTTTATCGCCATCACTTGAAAAAGTCTCACCATCGAATGATCATCAGCACAACAGTTCTCCAACGTATGCTTGTGAAAGTTGTACAATGCAGTTTGATTCGATTGAAAAATTAAGAGTGCATGAAAATTGCATCCATTGGAAACCTCCGCAACCACTAATTCCAAATCCTGCGGCGTTTATAAAGGATTGTAATACGTGTTTGCCACCGTCTCAAGGTATCAGTCCTGAAGTATTAAAGAATTCGCCAAATGCTCAACCTGTTCAGTCACAACCAACAGATTTAAGTCGTAAAAGGAGAGGTGGAGATATTGAAGATCAAGTTACTTCCAAAAGGAACAACAATGAAATTAATGCCACTCAAAGTATACCGAGCGGTTCCTCTCATGATTCTTCCAAGAAAGAAGAGTGGTCGAGTTACATTTGTAGCATATGTGGTACTCAGTTGCCAAATTTTGCTTCATTTATGGTGCACATGGACATACATATGTCTGTAAATGCTACTCCCACCAATGTCGTTTTGGGTGGTTATTGTCCTCTTTGTGGCGAGGCTTACAGGGATCAAACTGAACTCAATAATCACATCGTCCTACATACTTTAACGTACAAACCCGGCTGGTGCTGCcgtgtttgtaaaaaaatgttcaatgaGGATTTGGAAGATCTCCAAAGGCATTTAATGGAAAATCATACTTGCACTACTTACAGATGCTGCGTGTGTGAACAAATGTTTGAAACGAAAACTGCAATGTTGATGCATCTTACTAAAAAGCATAGCAGTGAATGCCAGCACTACCGCTGCAAATTTTGTCCGGAGCAAATTTTTCACAACCAAATCAGTGCAGAAATGCATATATCGCAGCATGTTCCTCGACTGTTTAATCCATCTCGGAAAACTGCTAGTTTCGGGCCCTTTCCATTTCGGAATGATTTCAACTCCAGGGTAGAAAGAATGGTTAAAAATCTTCAATGTCCTTTCTGTCGCCAGTGCTTTAAAGGCGAATACCTTCAACAAATACACATGATGAAAGAACACAAGGACTACCGAGAGGCACACAGCTCAAAAATGCAGGAAGAGTGTGCATTGGAGCAATTGTCTTCGTCCAGAGGACAACGAGAGATACAATCAAGCTCACCGAATGTATCGTATGCAAATCACTTGCCCTCTTCTGAAAGCATATCCAGATATGACAAGGCCCTAGCtgataattttatatgtgacaTCTGTGGTTCTACGGATTTTAATAGCGACACCGAGCTGGCCGCACATAAGAAGTTACATCATGTGAAGACCAAAGTGGGACCTGTGAGTTTACAATGTGCATACTGTAATGAACATTGTAAATCTCGCTCAGATTTAGAAAATCACATGAAGAACCATCAAATTAACAGCAGTAAAGGCAAACATAAGTGTAATATCTGCGACGAAATTTATTCTTCCGCTATTACATTAGCAGAACATAAACTATCACACTGTAAAATAGTATCTGGTAATACTTGTACACAGTGTAAAACAGTTCTTGCTGATGAACAATCATTTTATTCCCATCAACTGCAACACAGTGCGGTAATGAATAAGCCAAACTCACAAATTTCTTTACCAGCAAATTGCATTATTTGTTGCCAAACTTTACAGACGGATGTTGAAATTAAGCTGCACGCTAATTTCCATTTGCAACATTTAATTCAAAAGGAATTTCTTTGTAGTATGTGTAGCAGAATTTTTGATACCCGTACCGGTATCACTGTTCAGGGGTTTGATAAAAGCTcagaaaatctacaaatttctgtttgtaaagaatgtataaataaatgtgGCAATAATAGTAGTTCTAACAGTCCGCGACCTCCACTCCTAAAACCAGAAAACCTAGACAAAAGTTTATATTCGTGTATTAAATGTCCACAGACATTTGAAAATGAGAACGAAGTGAAAAAACATGCAGTCACCCATGTCGTCAACGACGGTATTAATCATGAATGTCATATTTGCAGAAGTATTTTCCCAACTCCTCTGAAACTTCAGCTACATGTTATTGAACACAGCTTTTTTGGAACTGGACAGTTTCGATGTTACATATGTAGTTCAGTTTTTACAACTGCAAACGGACTGCTCTCACATATGCTCGAACACGGAGCAAATGCCAAACCGTACGAATGTGCCACTTGCCAAATGAAATTCTTTTTCCAAACCGAACTAGACAACCATAAATACGAACATGTTCTATCTCGTGCTGTCGTTCAGCCtatcattttaaataacacagAAGAATGCGAAGATTCTTCAactgaaaaaatgaaaagggaACTGCTGAGGAAATGTCCATATTGTGATATGTCAACATCGCACACATACTTGGATGTGCATATTAGATTTTGCCCCCGAAACCCAGAGTTTAAgaaaaaactagaagaaaaacGCAAGGTTAAAGTATcggaaaaaacaaacaatatgtCCGAAAATGAGGATAAAAATGTATAA
- Protein Sequence
- MVFFLSGSIGTEHGSWGSNTPEQASPAPSSCPTPSSSLSDIAEAEISFTVGVTETTPYACKICNKAFARSSLLSKHEQSHTDQLQYGCSYCPRLFKHKRSRDRHIKLHTGDKKYKCIHCQTAFSRSDHLKIHMKTHDNSKPFRCLVCNRGYNTAAALTSHQQSHAKQNAENRQSPGSFRCLQCPEIFSRYDLLQIHTSSNHSSIAVNSSQQTIPVTIQDNNIKSHIELPKWVCMYCGKDFLTLDEMQQHVNTDHNAIVNGNFVSSPCKTAASDALSPSLEKVSPSNDHQHNSSPTYACESCTMQFDSIEKLRVHENCIHWKPPQPLIPNPAAFIKDCNTCLPPSQGISPEVLKNSPNAQPVQSQPTDLSRKRRGGDIEDQVTSKRNNNEINATQSIPSGSSHDSSKKEEWSSYICSICGTQLPNFASFMVHMDIHMSVNATPTNVVLGGYCPLCGEAYRDQTELNNHIVLHTLTYKPGWCCRVCKKMFNEDLEDLQRHLMENHTCTTYRCCVCEQMFETKTAMLMHLTKKHSSECQHYRCKFCPEQIFHNQISAEMHISQHVPRLFNPSRKTASFGPFPFRNDFNSRVERMVKNLQCPFCRQCFKGEYLQQIHMMKEHKDYREAHSSKMQEECALEQLSSSRGQREIQSSSPNVSYANHLPSSESISRYDKALADNFICDICGSTDFNSDTELAAHKKLHHVKTKVGPVSLQCAYCNEHCKSRSDLENHMKNHQINSSKGKHKCNICDEIYSSAITLAEHKLSHCKIVSGNTCTQCKTVLADEQSFYSHQLQHSAVMNKPNSQISLPANCIICCQTLQTDVEIKLHANFHLQHLIQKEFLCSMCSRIFDTRTGITVQGFDKSSENLQISVCKECINKCGNNSSSNSPRPPLLKPENLDKSLYSCIKCPQTFENENEVKKHAVTHVVNDGINHECHICRSIFPTPLKLQLHVIEHSFFGTGQFRCYICSSVFTTANGLLSHMLEHGANAKPYECATCQMKFFFQTELDNHKYEHVLSRAVVQPIILNNTEECEDSSTEKMKRELLRKCPYCDMSTSHTYLDVHIRFCPRNPEFKKKLEEKRKVKVSEKTNNMSENEDKNV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00789614;
- 90% Identity
- -
- 80% Identity
- -