Basic Information

Insect: Hemicrepidius niger
Gene Symbol: Znf423
Assembly: GCA_963082805.1
Location: OY720168.1:24881047-24890457[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.4e-06 0.00033 22.0 0.5 1 23 83 105 83 105 0.97

2 20 0.082 8.2 8.2 3.3 3 23 113 133 111 133 0.97

3 20 6.5e-05 0.0065 18.0 5.3 1 23 139 161 139 161 0.98

4 20 0.00026 0.026 16.1 0.3 1 23 167 189 167 189 0.99

5 20 0.00014 0.014 17.0 0.3 1 23 203 226 203 226 0.97

6 20 0.00021 0.021 16.4 0.4 3 23 250 271 248 271 0.96

7 20 1.5 1.5e+02 4.2 0.1 1 20 313 332 313 333 0.93

8 20 0.01 1 11.1 0.1 1 23 429 451 429 451 0.97

9 20 0.0001 0.01 17.4 0.0 2 23 466 487 466 487 0.97

10 20 2 2e+02 3.8 1.5 3 23 497 519 495 519 0.84

11 20 0.025 2.5 9.9 1.9 1 23 524 547 524 547 0.96

12 20 0.063 6.3 8.6 1.9 2 23 612 634 611 634 0.95

13 20 0.064 6.4 8.6 0.4 1 23 690 713 690 714 0.94

14 20 0.00046 0.046 15.3 4.4 2 23 725 746 724 746 0.97

15 20 0.0014 0.14 13.8 0.3 1 23 755 777 755 777 0.97

16 20 0.38 38 6.1 0.8 2 23 785 806 785 806 0.96

17 20 0.084 8.4 8.2 0.8 1 23 945 967 945 967 0.95

18 20 0.0012 0.12 13.9 0.3 1 23 975 997 975 997 0.97

19 20 0.39 39 6.1 1.7 1 23 1004 1026 1004 1026 0.94

20 20 1.8 1.8e+02 4.0 0.2 2 12 1060 1070 1059 1077 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.4e-06	0.00033	22.0	0.5	1	23	83	105	83	105	0.97
2	20	0.082	8.2	8.2	3.3	3	23	113	133	111	133	0.97
3	20	6.5e-05	0.0065	18.0	5.3	1	23	139	161	139	161	0.98
4	20	0.00026	0.026	16.1	0.3	1	23	167	189	167	189	0.99
5	20	0.00014	0.014	17.0	0.3	1	23	203	226	203	226	0.97
6	20	0.00021	0.021	16.4	0.4	3	23	250	271	248	271	0.96
7	20	1.5	1.5e+02	4.2	0.1	1	20	313	332	313	333	0.93
8	20	0.01	1	11.1	0.1	1	23	429	451	429	451	0.97
9	20	0.0001	0.01	17.4	0.0	2	23	466	487	466	487	0.97
10	20	2	2e+02	3.8	1.5	3	23	497	519	495	519	0.84
11	20	0.025	2.5	9.9	1.9	1	23	524	547	524	547	0.96
12	20	0.063	6.3	8.6	1.9	2	23	612	634	611	634	0.95
13	20	0.064	6.4	8.6	0.4	1	23	690	713	690	714	0.94
14	20	0.00046	0.046	15.3	4.4	2	23	725	746	724	746	0.97
15	20	0.0014	0.14	13.8	0.3	1	23	755	777	755	777	0.97
16	20	0.38	38	6.1	0.8	2	23	785	806	785	806	0.96
17	20	0.084	8.4	8.2	0.8	1	23	945	967	945	967	0.95
18	20	0.0012	0.12	13.9	0.3	1	23	975	997	975	997	0.97
19	20	0.39	39	6.1	1.7	1	23	1004	1026	1004	1026	0.94
20	20	1.8	1.8e+02	4.0	0.2	2	12	1060	1070	1059	1077	0.85

Sequence Information

Coding Sequence: ATGTTATTTAAGGGTAATAGCAGTCGATTGGAATTGTTGATTGAAAAAATTCATACcaataaagaaaatacagaAATTGGAGAAGCAATAACAGGGTCAATTGGAACCGAGCATGGAAGTTGGGGTTCTAATACCCCAGAACAGGCTTCACCAGCACCTAGTTCCTGCCCAACCCCAAGTTCGAGCCTAAGCGATATAGCAGAAACAGAAATTGCTTTTACTGTAGGGGTTACAGAAACCACTCCTTATGCTTGTAAAATTTGCAATAAGGCTTTTGCCAGGTCGTCCTTGCTAAGCAAACACGAACAGTCGCACACAGATCAATTGCAATATGGATGCTCCTACTGTCCCAGGTTGTTTAAACACAAGAGATCCAGAGATAGACATATTAAACTTCACACCGGTGACAAGAAATATAAATGTATTCACTGCCAAACGGCGTTTTCAAGAAGtgaCCATTTGAAAATTCATATGAAGACGCACGATAACAGCAAACCATTCCGTTGCTTAGTGTGCACTCGAGGGTATAACACTGCAGCGGCACTCACTTCTCATCAACAAACACATAATAAGCAAAATACGGACAACAGACACAGTCCAGAAAGTTTCAAGTGTCTTCAATGTCCGGAAATCTTTAGTAGATATGATTTGCTACAGATACATATATCTTCCAACCACAGTGCAATTGTGGGCAACTCTCCTCAACATAATGTACCTATAACTATACAAGAAAATGCTATGTGGGCTTGCATGTATTGCGGTAAAGACTTTATAACACGCCCAGAGATGCAGCATCATATTAATACAGAACATAATGCACTCCTAAATGGGGACTTTACAGGAAATTGTTCGAAAGGCACTGCAACCACAGATACTTTATCGCTTTCTAGCGATAAAGCTTCTCCATCCCACGATCAACCCAACAGCTCACCTACGTATGCTTGCGACAGTTGTACCATGCAATTCGATTCGATTGAAAAGTTAAGGGTGCATGAAAACTGTATCCATTGGAAACCGCCGCAACCATTGATACCAAATCCTGCATCATTTATCAAGGATTGCAATACGTGCCTACCTCCAAGTCAAGGAATTAGTCCTGAAGTACTAAATAACTCCCCCAGTACTCAACCTGTTCAGTCACAACCAACAGACTTAAGTCAAAAAAGGCGAGGGGGTGATATAGATGATCAAATCGCGccaaaaagaaataatattgaCAGAAATTCTTCCCAAACCATTGCTAGTAGTTCCCAAAATTCTTCCAAAAAAGAAGAATGGTCAAGTTATATCTGTAGCATATGTGGTACCCAATTACCAAATTTTGGTTCGTTTATGGTGCACATGGATATTCATATGTCTGTCAATGCAACCCCTACTAATGTCGTTTTGGGAGGATATTGTCCTCTTTGTAATGAAGCTTACAGAGACCAAGCTGAGCTCAACAATCACATTTTAATACACACTTTAAGTTACAAAACAGGATGGTGCTGTCgagtttgtaaaaaaatgtttaatgaagaCTTGGATGAGTTACAAAGGCACTTAATGGAAACCCATGCTTGCACAACTTATAGATGTTGCGTGTGTCAACAAATGTTCGATAGCAAAGCCGCAATGTTGgtgCACTTAACAAAGAAGCATAGTTTGGAATGTCAACATTACCGTTGTAAATTTTGCCCAGAACAAATTTTCCACAATCAGATTAGTGCTGAGATGCATATATCACAACATATACCACGATTGTTTGATCCATCCCGCAAAAGTACAGCTTTCGGTCCGTTTCCTTTCCGTAACGATTTCAACTCTAGGGTTGAAAGAATGGTTAAAAGCTTGCAGTGTCCGTTTTGTCGACAGTGTTTCAAAGGAGAATATCTACAGCAAATGCACATGATAAAAGAACATAATAGAGAGGCACATAGTTCAAGAATGCCTGATGATACCATCGAGCAATTATCTTCTACCCGAGGACAAAGAGAAGTTCCACCCAGCTCACCAAATGTTTCATACGCCAACACCTTGCCTTCATCTGAAAATATATCTAGATACGAGAAAACTTTAACTGATAATTTTATATGTGATATCTGTGGTTCTACAGATTTTAATACTGAAACGGAGTTGGCTGCTCATAAAAAATTACATCACGTAAAAACCAAAGTAGGTCCAGTAAGCTTACAATGCGCGTATTGTAACGAACACTGCAAATCTCGTTCAGATCTGGAGAATCATATGAAGAACCATCAAATAAATAGCAGTAAAGGTAAACATAAGTGCAATATTTGTGATGAAATTTATTCTTCTGCCATCACGCTAGCCGAGCACAAATTATCCCACTGTAAAATAGTTTCAGGAAATACTTGTACGCAGTGTAAAACAATTTTGACCGACGAACAGTCTTTTTATGCTCATCAATTACAACATAGTGCAGTGTTAAATAAGTCCAATTCACAAATATCTTTGCCTGCAAATTGTATAATTTGCTGCCAGACATTACAAACGGATGTCGAAATAAAACTTCACGCAAACTTCCATTTACAACATCTTATTCAGAAAGAATTTCTTTGTAGTATGTGTAGTAGAATTTTTGATACACGTACAGGAATAGTTGTTCAAGGATTTGACAAAAGTTCTGAAAGTTTACAAATTTCTGTATGTAaagaatgtttaaataaatgtgGAAGCAATAGCTCCTCTAACAGCCCTAGGCCACCAACTATGAAGACTGAGAATACAGAAAAGAATCTCTATTCGTGTATAAAATTTCCACAAACTTTTGAAAACGAAAATGAAGTTAAAAAGCATGCAGCTACCCATGTTGTTAATGATGGCACTAATCATGAATGTCATATTTGTAGGAGTATTTTTCCAACCCCGTTAAAACTCCAGTTACATGTAATAGAACATAGTTTCTTTGGAACAGGACAATTTCGGTGTTACATTTGCAGTTCAGTTTTTACCACGGCAAATGGATTGCTTTCTCACATGCTGGAACATGGTGTAAATGCTAAACCATACGAGTGTGCAACTTgccaaatgaaattttttttccaaacagAATTAGATAACCACAAATACGAGCATGTGTTGTCTAGAGCAGTTAATCAGCCGATTATTATAAATAGCAATGACGAATCTGAAGAGTTATTATCGGAAAAAATAAAACGAGAACTAATATCTAAAAAGTGTCCATATTGTGATATGACAACATCTCATACATACATGGATATACATATTGGAGTGTGTCCTCAGAATCcagattttaagaaaaaacaagaAGATAAACGTAGGCTCaagttttctgaaaaaactAATAATATGACTGAAGCTGAAGCTAAGAAAGCCTAA
Protein Sequence: MLFKGNSSRLELLIEKIHTNKENTEIGEAITGSIGTEHGSWGSNTPEQASPAPSSCPTPSSSLSDIAETEIAFTVGVTETTPYACKICNKAFARSSLLSKHEQSHTDQLQYGCSYCPRLFKHKRSRDRHIKLHTGDKKYKCIHCQTAFSRSDHLKIHMKTHDNSKPFRCLVCTRGYNTAAALTSHQQTHNKQNTDNRHSPESFKCLQCPEIFSRYDLLQIHISSNHSAIVGNSPQHNVPITIQENAMWACMYCGKDFITRPEMQHHINTEHNALLNGDFTGNCSKGTATTDTLSLSSDKASPSHDQPNSSPTYACDSCTMQFDSIEKLRVHENCIHWKPPQPLIPNPASFIKDCNTCLPPSQGISPEVLNNSPSTQPVQSQPTDLSQKRRGGDIDDQIAPKRNNIDRNSSQTIASSSQNSSKKEEWSSYICSICGTQLPNFGSFMVHMDIHMSVNATPTNVVLGGYCPLCNEAYRDQAELNNHILIHTLSYKTGWCCRVCKKMFNEDLDELQRHLMETHACTTYRCCVCQQMFDSKAAMLVHLTKKHSLECQHYRCKFCPEQIFHNQISAEMHISQHIPRLFDPSRKSTAFGPFPFRNDFNSRVERMVKSLQCPFCRQCFKGEYLQQMHMIKEHNREAHSSRMPDDTIEQLSSTRGQREVPPSSPNVSYANTLPSSENISRYEKTLTDNFICDICGSTDFNTETELAAHKKLHHVKTKVGPVSLQCAYCNEHCKSRSDLENHMKNHQINSSKGKHKCNICDEIYSSAITLAEHKLSHCKIVSGNTCTQCKTILTDEQSFYAHQLQHSAVLNKSNSQISLPANCIICCQTLQTDVEIKLHANFHLQHLIQKEFLCSMCSRIFDTRTGIVVQGFDKSSESLQISVCKECLNKCGSNSSSNSPRPPTMKTENTEKNLYSCIKFPQTFENENEVKKHAATHVVNDGTNHECHICRSIFPTPLKLQLHVIEHSFFGTGQFRCYICSSVFTTANGLLSHMLEHGVNAKPYECATCQMKFFFQTELDNHKYEHVLSRAVNQPIIINSNDESEELLSEKIKRELISKKCPYCDMTTSHTYMDIHIGVCPQNPDFKKKQEDKRRLKFSEKTNNMTEAEAKKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01345944; iTF_00978666;
90% Identity: -
80% Identity: -