Msca022012.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melanostoma scalare
Gene Symbol
RREB1
Assembly
GCA_949752695.1
Location
OX456985.1:22795901-22801735[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.036 9.3 8.8 0.8 1 21 232 252 232 254 0.93
2 14 0.00034 0.087 15.2 0.2 1 23 264 286 264 286 0.98
3 14 9.7e-06 0.0025 20.0 5.2 1 23 292 314 292 314 0.98
4 14 0.08 21 7.7 2.2 2 19 516 533 516 533 0.97
5 14 4.7 1.2e+03 2.2 0.6 1 19 579 597 579 599 0.78
6 14 0.009 2.3 10.7 0.1 1 23 748 770 748 770 0.97
7 14 0.00018 0.047 16.0 1.7 1 23 779 801 779 801 0.99
8 14 0.00032 0.083 15.2 2.1 1 23 807 830 807 830 0.97
9 14 0.00096 0.25 13.8 2.1 1 23 1180 1203 1180 1203 0.95
10 14 8.7e-05 0.022 17.0 0.3 2 23 1509 1530 1508 1530 0.97
11 14 0.15 38 6.9 6.3 1 23 1536 1559 1536 1559 0.97
12 14 3 7.9e+02 2.7 6.3 1 23 1665 1687 1665 1688 0.95
13 14 0.085 22 7.6 1.1 3 23 1737 1757 1736 1757 0.91
14 14 0.0014 0.36 13.2 4.8 1 23 1763 1785 1763 1785 0.99

Sequence Information

Coding Sequence
ATGTTGAAAACAGCAATCAAAAAGGAATTAACTGACACACAATTGCGAAAAATGGATCGACGCGAATCAACAACATCAGACTCATCTGTAGAACCCATGGACCTGGGTCGTTCGAGTTTGAAAATGACTAAATCTGGAATGGTAGACCATTGCATAGACCTGccaaaaacaacacaaactAAGGATGCCATTTTATCAGATGCCAATATTAAGTATCGTTATGAATCTGACGCTGACGAATCAGATGACCGCGATAGAGATCATCAAAGAAGATCACATAGTCAACATCACTATCATCATCGACGGCGCGGTAATAATGGACGTGACAAGCGTACTGTTCATTTAGAATTCACCGATAGCCCACATTCATTGCGAAAGAAATTTCGCTTTAGCAGTAATCATAATATTTCCGAAGCTGTGATTAATTTGAAATCGAAAACATCGAACAACGAATCCACAAATTCAACAACAACGGGTTCAACAAATTTGACATCAACAACGAATAACAATGAATCGGGTTTTGTGGATGCCAGTGTAAGCCATGTTCTTAATACATCAGCTTCATCAGCAACATCATCTGCATCGTCATCATCGCCCACATCCTCGTCGTCGGCTTCACCAACCGCCAGTAATATTGCATCGGCTGTGTCTAGCCCCGAATCGGGAGGCATCGGTGAACGTGACGACATGAAGTACCTTTGCCCAATTTGTGAAGTGGTCTCGGCGACACCCCATGAATTTACCAATCACATACGGTGTCATAATTATTCATCTGGGGATACCGAAAATTTCACCTGCCGCATATGCTCCAAGGTTCTGTCATCAGCCTCGTCTTTAGACCGCCATGTTCTGGTTCACACCGGAGAGCGGCCCTTCAACTGCAAATATTGTCAACTGACATTTACAACAAATGGCAATATGCATCGTCACATGCGAACACATAAACAGCACCAGCAACACTATCACCGTAATTCAAATGGGACAAAAGGTGGTGGTGGCAACTCCAGTTCATTACCAGTTTTGCCATCTACCGACCAATCGGCCGCAGCTCAAACAGCAACCACTGCTAATTCTGTGCCATCAAAAACAGCAGCAAACACAAGCAATGGTATTATTTGTAATGGCAATGGCGACACAATTGCCGATGGAGGTGGTGgcagtggtggtggtggtgataGTTATGACAGCGATGGTGGTTGCTCAACAGATTCATCAAGTGGCGTCAGCCAAAGTtccaacaataacaataacagcaataccaacaacaaaaacataagCAATTTTAAACGCAAGAGTACCGACAGTTTGGATGACATGGCAATGATGAAACGACGCGTTAAGACCACAATTAACAATAACAACATAATCGATAACATTCACACTATAACCGAAAAGAATGCGACCGAAGTGCCAGATGCTATGGGAGAGGTAAAAcaagagcaacagcagcagaAACTTGTTTGTCCGGTGTGCAATCGGAGTGATTTTGATGGGATGCTTGTGTTGGGCTCCCATATGGATAGCGATCACTCGGACATTCCGGCCAAGTGTCGCCATTGCGATGTGATTTTCAAAACGCATAGGCAGCTAAACGTTCATCCATGCACTAGTAAGCTAAAAATTACACATGGCTTCAAGGACATGACGTTTATAGACTTCTCTAGTGAAAAATTCCCGCTAATCGCAAAATCCTTGTGTGAACAAAGTCTTCGGGCGTCTGTTGGGAGCCAGAGATTTGAATGCTCAAAATGTTATCGAGCGTTTCCATGTGCCAGTGCAGTTGAAATTCACGAGAAAGACTGTGCCACTTCAGGAATGAATCTTTATGTTGATTTTTCGAAACGCAAGCAGAGGACCTACAGCGAGAGCTCTGAAGGTGCTGATGATGACGACAATCGACGAGAGGAATTCTTCAACCGCTTGTACTTGACTAACAAATCCACGGCACAAAGTATGACTAGTCTTTCTGTTTCGTCACCATCCTTGTCCGATGTTAAGTCGTCCGAGTTGGATAAAACTCCCGTCAAGTTGTCCCAGTTGGAGCAGTTCCAGGACACCAAGGAACTTGCCGATATTCAATCGATCCTTAATATAACGTCATCGTCGTCAACAAGTAATTTTCTGCGCAATTTTGAGAACTCGGTGAACGCACCCATTAGCAACTATGGAGCTGAAAATGGCGAAGAAGAAGCTCAGGACGCTTTCACCTCGGAGTTCCGTAAGATGAAACTGCGTGGAGAGTTTCCCTGCAAATTATGTACAGCAGTGTTTCCCAATCTGCGAGCTCTCAAAGGCCACAATAGGATTCATCTCAGCGCAGCTGGACCCGGTCCATATCGTTGTAACATGTGTACTTACTCTATACATGACAAAGCAGCTCTCGTCCGTCACATGCGAACGCACAATGGTGACAGACCGTACGAGTGTGGGATCTGTAACTATGCATTTACCACAAAAGCCAATTGCGAACGACACTTGCGAAACCGTCATGCAAAGACTACTCGCGATGAAGTAAAACGTGCCATCATCTACCATCCGTCGGAGGACTCAAACTGTGATGACGCTATGAAGAAGCTGCACATGTTTTCGTCTCCTGAGTTTGACCAAGACGACATGGAACAGCATCACCCGCCAAAAGATCGCTCCACACCAGTGTCACACTTAAAGGAGATGCTTCAAGCCGACTCTAAGCCCATGAAAATTCAAGTTAAGAGTCTGGAGAAGTTGATTGACAAGCCATCATTCAATCAGCCCGATGAGCCGGAGCATAGCCCAGTGCTAGCTGAATGCGAAGAAGACAAGTCGAACATCCGACCCATTGACCTCAGCATGGATGTCTTGGATTTGAGTAAAAAATctgtaaaaacagaaaaagtagAAGAGAAGCGACCAAAAACTCCTACTCCAGTTCCACAAGCAGCTCCGGTTCGTTTACCAGTCGACGAACAAAGCATCGACATGCGACTTCTCGAAAAGAACCAACAACTATTGTTAGCCCAACAACGGCTCCTCAACGAAGCCATGCCAAAAATGGACCCCGCACACTATTTCCAATTGTCTCAGCTGTACAGAAACCTAGTGTTCCAACCGTTGAATCCCTTCTTCTTACCAAACTCCTTTCTATCGAATAACATTAGTGATTTGAATAAATATGTTCCCTTAATGAATCCTATGTTTGGCGGACCAGCTTCAGATGTCCTGACTTCAGTGGCAGCACCTGAGAACCATAACCAAACTACACAGCAGCCAAAGCTTGCTCAAGAAGACACAGGTCCATCGCTGAATCAGTCTAGCTCACGTGCTCAATCGCCGCCATTGCCCACGAAGAGCCAACTCGTACCCTCAAGAAATTCAACTCCCTCTCAAATATCACAAATGCCAGCTCTACCACGAAATCATCAGCATCTCATGACAGGATCACATTCTTCTGGAATGCTTCCATCATCTCTGCCCAACTCGGGGCCTGTGAAGATGGTTATTAAGAACGGTGTTCTTATGCCAAAGCAAAAACAACGTCGTTACCGCACCGAGCGTCCCTTTGCTTGCGAACATTGTTCAGCACGATTCACCCTGCGCTCCAACATGGAACGACACATTAAACAACAACATCCGCAGTACTGGGCACAGAGGCAACGCAGTGGTCACCACATAATGCGAGGTCGTTCCAACAGCTCATCTGTTCTATCTCATATGCAGTCAGGTCATTCGTCTCTCGAAGCCCCGCATCCGATTGGCGGCAGTGGCATGATGACAAATCCCTTGAGTGCCATCTCCGATCAAGTCAAATATGCAATACTAGCACAGCAGCTGAAGGCCCGAAAGGACACAGACATTCTTCAACAAGCCCTCTCCCAGGGTTCCAGCAGTGTTTTAACGCAGAGTCCCACTTCTACTATAAGCAACCTTCGCCAGACATTGAATGCTTCATCGCATGCTAATAATGGAAGTACAGAAGATGATGATCCGAAATTAGTCATCGATGAAGATGAGGATGATCAGGaggaagaagacgaagaagaggaGTGTCAAGAAGATCGAAAACCTGAAAATTTGACCAAACTGCATGATCTTCAAGAGCAGGCAACCAACGAAGCCGCTAAGAAAGTAGCCGAATCTATCCTTGAACAGGCTATGAAAGCTGGAAACACGAAGAAATCATTTACCAAAGAGGAAGATCGTGATCGGACAGCGGGGAAAGATTTTAGCCTAAAATTATCAAAGAATATGCTTGCTCAAGCCGAGTCAGTTGGTAAATTCCTTAAAGAAGTGGCCAGCTCTCCGTTCAAAGATGAATCCAGCGATCTCGCATCGGTATCTAGACTAGTAGATAACGCAACTAACTCCATGTCGTTCAACAACTACTTCAGGCCAAGTGACGTGGTTAACCAAATGGAACAAAGTGACGAAGAAGGTCTTGTCGCTTCGGGCAGTGCATCGGAGAGCAATAACTCCGGCCCTGAGGACATGATCAGTTCACAGGAACCAAAGAAAAAGTCAGCATACAGCTCAGCACCAAATCGTGTCTCGTGCCCATATTGCCAACGTATGTTCCCTTGGTCCAGCTCATTGCGACGCCATATCCTCACCCATACTGGCCAAAAACCCTTCAAATGCTCTCATTGCCCATTGCTTTTTACCACCAAAAGCAATTGCGATCGTCATCTATTACGAAAGCATGGAAACGTTGAATCAGCTGTCTCATTGTATGTCCCCATCGAGGACGTAAATGAACCTCTGCCAGTACCTAAGTCTGTTGAAGAGATCGAGTTGCAACAGCAACAAAAGCTCCTCCAACAAAAGCAGCAAAAAAAGTTGGAAGAACTTAGGGAAATGGAAAAAACTCAAACACAACCGCAGAAGCAACCCGAAATTAACCAGGAGGTAATATCAAGTACAAGCTCAACAAACCTCACACCAGTGGGAGCTATCTCAACGAGTTCCAAGTTGGACACAGTTCCTGCATCACAGATAGTCTCGTCGTCAGAATTGCCCTTTAAGTGCCATCTCTGTGACAGTTCGTTTGCAGAACGATTTCAGTGCCTCGATCACATAAAGATTCACCATGCTCAAGAATTTTCATTGCTTTTGTCCAAGGGGGCGATTGACAACGAAGCCGATCTCAATAGCCATGTCCAGTCAACCGAAGACGACGAAAAACGCGATGAAAGCAGAGGCAAGTATCCCGACTACACCAACCGGAAGGTTATATGTGCCTTTTGCATGCGCCGCTTCTGGTCCACAGAAGACCTTCGTCGTCACATGCGAACTCACTCTGGTGAAAGGCCATTCCAGTGCGATATCTGCCTGCGAAAGTTTACTTTGAAGCACAGCATGTTACGCCACATGAAAAAGCACAGCGGTGGTAGTCACTCTAGCAATGGGGCTACCAATGCTGGGAACAGTGGATCGGATGTCTCCGACGATGAACAGCCGCCATCTAGTGTCATGCTTGCGAATGCCCTTCGCTCTCACAAAATCCAGGAGCTTTTTTCGAAAGTTAACAGCGAGTGGCGCAACAATCGACTCTCTGGTGAGCACAAAGAGAACATCGAAGAGCACAACAACCAGTCCGACCTAATTGGAAACTTACTTGGCATCAGTGACCAAGGCATCTTGAACAAATTACTCTCATCGGCCGATGAAGCTGCCAAGTTTTTAGGTGTCGAAAAGTAA
Protein Sequence
MLKTAIKKELTDTQLRKMDRRESTTSDSSVEPMDLGRSSLKMTKSGMVDHCIDLPKTTQTKDAILSDANIKYRYESDADESDDRDRDHQRRSHSQHHYHHRRRGNNGRDKRTVHLEFTDSPHSLRKKFRFSSNHNISEAVINLKSKTSNNESTNSTTTGSTNLTSTTNNNESGFVDASVSHVLNTSASSATSSASSSSPTSSSSASPTASNIASAVSSPESGGIGERDDMKYLCPICEVVSATPHEFTNHIRCHNYSSGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCKYCQLTFTTNGNMHRHMRTHKQHQQHYHRNSNGTKGGGGNSSSLPVLPSTDQSAAAQTATTANSVPSKTAANTSNGIICNGNGDTIADGGGGSGGGGDSYDSDGGCSTDSSSGVSQSSNNNNNSNTNNKNISNFKRKSTDSLDDMAMMKRRVKTTINNNNIIDNIHTITEKNATEVPDAMGEVKQEQQQQKLVCPVCNRSDFDGMLVLGSHMDSDHSDIPAKCRHCDVIFKTHRQLNVHPCTSKLKITHGFKDMTFIDFSSEKFPLIAKSLCEQSLRASVGSQRFECSKCYRAFPCASAVEIHEKDCATSGMNLYVDFSKRKQRTYSESSEGADDDDNRREEFFNRLYLTNKSTAQSMTSLSVSSPSLSDVKSSELDKTPVKLSQLEQFQDTKELADIQSILNITSSSSTSNFLRNFENSVNAPISNYGAENGEEEAQDAFTSEFRKMKLRGEFPCKLCTAVFPNLRALKGHNRIHLSAAGPGPYRCNMCTYSIHDKAALVRHMRTHNGDRPYECGICNYAFTTKANCERHLRNRHAKTTRDEVKRAIIYHPSEDSNCDDAMKKLHMFSSPEFDQDDMEQHHPPKDRSTPVSHLKEMLQADSKPMKIQVKSLEKLIDKPSFNQPDEPEHSPVLAECEEDKSNIRPIDLSMDVLDLSKKSVKTEKVEEKRPKTPTPVPQAAPVRLPVDEQSIDMRLLEKNQQLLLAQQRLLNEAMPKMDPAHYFQLSQLYRNLVFQPLNPFFLPNSFLSNNISDLNKYVPLMNPMFGGPASDVLTSVAAPENHNQTTQQPKLAQEDTGPSLNQSSSRAQSPPLPTKSQLVPSRNSTPSQISQMPALPRNHQHLMTGSHSSGMLPSSLPNSGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWAQRQRSGHHIMRGRSNSSSVLSHMQSGHSSLEAPHPIGGSGMMTNPLSAISDQVKYAILAQQLKARKDTDILQQALSQGSSSVLTQSPTSTISNLRQTLNASSHANNGSTEDDDPKLVIDEDEDDQEEEDEEEECQEDRKPENLTKLHDLQEQATNEAAKKVAESILEQAMKAGNTKKSFTKEEDRDRTAGKDFSLKLSKNMLAQAESVGKFLKEVASSPFKDESSDLASVSRLVDNATNSMSFNNYFRPSDVVNQMEQSDEEGLVASGSASESNNSGPEDMISSQEPKKKSAYSSAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAVSLYVPIEDVNEPLPVPKSVEEIELQQQQKLLQQKQQKKLEELREMEKTQTQPQKQPEINQEVISSTSSTNLTPVGAISTSSKLDTVPASQIVSSSELPFKCHLCDSSFAERFQCLDHIKIHHAQEFSLLLSKGAIDNEADLNSHVQSTEDDEKRDESRGKYPDYTNRKVICAFCMRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGGSHSSNGATNAGNSGSDVSDDEQPPSSVMLANALRSHKIQELFSKVNSEWRNNRLSGEHKENIEEHNNQSDLIGNLLGISDQGILNKLLSSADEAAKFLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01223735;
90% Identity
-
80% Identity
-