Basic Information

Insect: Melanostoma scalare
Gene Symbol: ZEB2
Assembly: GCA_949752695.1
Location: OX456985.1:20542702-20544968[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00043 0.11 14.9 0.3 1 23 193 216 193 216 0.93

2 14 0.022 5.7 9.5 0.6 3 23 229 250 228 250 0.93

3 14 0.012 3 10.3 1.0 5 23 260 279 258 279 0.91

4 14 0.16 40 6.8 0.3 2 23 283 304 282 304 0.89

5 14 7.5e-07 0.00019 23.5 0.6 2 23 318 339 317 339 0.97

6 14 0.002 0.53 12.7 2.8 1 23 345 368 345 368 0.96

7 14 0.42 1.1e+02 5.5 2.5 3 21 380 398 379 400 0.92

8 14 0.019 5 9.6 1.4 3 23 412 433 410 433 0.90

9 14 7.1e-05 0.018 17.3 3.6 2 23 441 462 441 462 0.98

10 14 0.0001 0.026 16.8 3.7 1 23 468 490 468 490 0.98

11 14 3.5e-07 9.1e-05 24.6 0.6 2 23 496 517 495 517 0.98

12 14 0.0009 0.23 13.8 3.3 1 23 523 545 523 545 0.98

13 14 0.0016 0.41 13.1 1.1 1 23 550 572 550 572 0.96

14 14 0.0001 0.026 16.8 1.9 1 23 577 600 577 600 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00043	0.11	14.9	0.3	1	23	193	216	193	216	0.93
2	14	0.022	5.7	9.5	0.6	3	23	229	250	228	250	0.93
3	14	0.012	3	10.3	1.0	5	23	260	279	258	279	0.91
4	14	0.16	40	6.8	0.3	2	23	283	304	282	304	0.89
5	14	7.5e-07	0.00019	23.5	0.6	2	23	318	339	317	339	0.97
6	14	0.002	0.53	12.7	2.8	1	23	345	368	345	368	0.96
7	14	0.42	1.1e+02	5.5	2.5	3	21	380	398	379	400	0.92
8	14	0.019	5	9.6	1.4	3	23	412	433	410	433	0.90
9	14	7.1e-05	0.018	17.3	3.6	2	23	441	462	441	462	0.98
10	14	0.0001	0.026	16.8	3.7	1	23	468	490	468	490	0.98
11	14	3.5e-07	9.1e-05	24.6	0.6	2	23	496	517	495	517	0.98
12	14	0.0009	0.23	13.8	3.3	1	23	523	545	523	545	0.98
13	14	0.0016	0.41	13.1	1.1	1	23	550	572	550	572	0.96
14	14	0.0001	0.026	16.8	1.9	1	23	577	600	577	600	0.97

Sequence Information

Coding Sequence: atggcaaaagtgGAATTATCGCCTTATTGTCGTGTCTGTATGAATTATATTTCTGTAGAATATATTGATCTGGATACTCCAATGAATGATTCAACTTACTTGGAATGTTTCAATTATTGCACAAATCTGAATGTTGTACTTCAAGATGAACTTCCAAAAACAATTTGTATTTCTTGTGGCGAATCATTACAAACAGCATATGATTTTATAAAAGCTGCAAAGGAAGCTGATAATTTCCTTCGTGAAAATTTTAATCCTGATCTCAAGAATGAGCCACTTTCAGTggaatcccattccaaagtACCAAACGTTTTTGGTTCTTATCAAATGAAACATGAAGTAgaagaaatttgttttgaagaCGTAGAGCAAACAGATACACGCCCCACATTTGAAGTTATTTTCCATGATGAAATACCCAAAGACCATAATGTGGTCAACGATTTGCCGCCATATCAAAAGGATATTCTGGCCGATGATAACTTgaaactaaacaaaattaccaTTGAGAATGGAGGAGTGATTGAAGATAGTATGGACAGCACGGACAATGTGACACAAGAAGATATCAAGCTCTTTAGATGCACGAAATGCAAGGAGGCTTTCGTGAAAGCAAGAGACTTGAATGACCACGTATCAGAAGTTCATAATTACGTAAACATCGATCCAAAAATTAATTTGCTTTGTAGATTGTGTGGAGAAACGTTTTTAAACCGAGCAACCCTTACTAGACATAAAATCAACGATCACAAAGACAAGGATAAAGGCTTGTGCATCAAATGCAACCAATCATTTAATGATGAAAATAGTCTGCGAAAACACGTTCAAGAAAAACACTCTCAAGTTGAATGTGAATATTGCAATGAAACATTCCCAGCTATAAGAATTAAAAAACACATAAGGAATAAGCATTGCGATTTACTTCTCTCTATCACAAACACGAACAACTTAACTTGTAAATATTGTCCAAAGGTCTTTACCAGTGAAAGTTCCCTACAGGAACATGAAAACACACATACAGGTTTACGACCTTATACGTGTGAAATTTGTGGAAAAGGTTTTCATGCTAAAAAGAACCATACAACTCACATGCGAGCGATCCATGATAACGAGCATGAACTTGACGAACCTCGGGCATGTACAAAATGCGACTTCACCACAACCAACAGATGGTCATGGATCAAACATGCTAAATGCCACGCTAAACCAAAGATTAATATAAAGAGACACCTCTGTTCATTTTGCCcaaTGACATTCTTTTCTCCCAAATACCTCAGAGAGCATGAAAGCTACGCGCATGGTGATAAAGAAAGTGCTCCTCAGTGTGAAATTTGTAAACGAAAATTTGCAAATAGTGTTTGTTTGAAAACTCACATGACTACACATTCTGATGAGCGTAAATATAAATGCAAAGAATGTCCCAAAACATTTAAATTCATGTGTACATTGAACGCTCATGAAAAAATACACAAAGGCAAGGACGTTCAATGTCCGCATTGTGATAAAAAGTATGTAACACCTGGTGACTTAAGAGTTCATCTCAGGAAGCATACTGGCGAACAGCCGTTTGAATGTCACTTGTGCGACAAAAAGTTTGCTATCAAAGTGAGGCTGACTTATCATTTGAAAAAGCACGAAGGAGTGCTATACAAATGCACTCGTTGTCCACAAGAATTCAGCTCCATTGCAAAACTACGTGTTCATACCTTCCAACACATTGGCTACCCGTATATTTGTGATCATTGTGAAATGGGATACGAAAGAAAAAGAGGCTTGTTTCGCCATATGAAGAGGGAACACAAAATAGTCATGACTGAAGAAGATTTAAAACAGAACCACTTAAAAAATTCCTCTAAATATTACAGACCCAAAGAAGAGCCATTCGAAGTCGAAGAAGAAATTACAGAAGTGTAA
Protein Sequence: MAKVELSPYCRVCMNYISVEYIDLDTPMNDSTYLECFNYCTNLNVVLQDELPKTICISCGESLQTAYDFIKAAKEADNFLRENFNPDLKNEPLSVESHSKVPNVFGSYQMKHEVEEICFEDVEQTDTRPTFEVIFHDEIPKDHNVVNDLPPYQKDILADDNLKLNKITIENGGVIEDSMDSTDNVTQEDIKLFRCTKCKEAFVKARDLNDHVSEVHNYVNIDPKINLLCRLCGETFLNRATLTRHKINDHKDKDKGLCIKCNQSFNDENSLRKHVQEKHSQVECEYCNETFPAIRIKKHIRNKHCDLLLSITNTNNLTCKYCPKVFTSESSLQEHENTHTGLRPYTCEICGKGFHAKKNHTTHMRAIHDNEHELDEPRACTKCDFTTTNRWSWIKHAKCHAKPKINIKRHLCSFCPMTFFSPKYLREHESYAHGDKESAPQCEICKRKFANSVCLKTHMTTHSDERKYKCKECPKTFKFMCTLNAHEKIHKGKDVQCPHCDKKYVTPGDLRVHLRKHTGEQPFECHLCDKKFAIKVRLTYHLKKHEGVLYKCTRCPQEFSSIAKLRVHTFQHIGYPYICDHCEMGYERKRGLFRHMKREHKIVMTEEDLKQNHLKNSSKYYRPKEEPFEVEEEITEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00976755;
90% Identity: iTF_00976755;
80% Identity: -