Basic Information

Insect: Melanostoma scalare
Gene Symbol: ZEB2
Assembly: GCA_949752695.1
Location: OX456985.1:20551292-20553477[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00041 0.1 14.9 0.3 1 23 166 189 166 189 0.93

2 14 0.021 5.4 9.5 0.6 3 23 202 223 201 223 0.93

3 14 0.011 2.9 10.4 1.0 5 23 233 252 231 252 0.91

4 14 0.15 38 6.9 0.3 2 23 256 277 255 277 0.89

5 14 7.1e-07 0.00018 23.6 0.6 2 23 291 312 290 312 0.97

6 14 0.0019 0.5 12.8 2.8 1 23 318 341 318 341 0.96

7 14 0.39 1e+02 5.5 2.5 3 21 353 371 352 373 0.92

8 14 0.018 4.7 9.7 1.4 3 23 385 406 383 406 0.90

9 14 6.8e-05 0.018 17.4 3.6 2 23 414 435 414 435 0.98

10 14 9.6e-05 0.025 16.9 3.7 1 23 441 463 441 463 0.98

11 14 3.5e-07 9e-05 24.6 0.6 2 23 469 490 468 490 0.98

12 14 0.0013 0.34 13.3 3.2 1 23 496 518 496 518 0.98

13 14 0.0015 0.39 13.1 1.1 1 23 523 545 523 545 0.96

14 14 9.7e-05 0.025 16.9 1.9 1 23 550 573 550 573 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00041	0.1	14.9	0.3	1	23	166	189	166	189	0.93
2	14	0.021	5.4	9.5	0.6	3	23	202	223	201	223	0.93
3	14	0.011	2.9	10.4	1.0	5	23	233	252	231	252	0.91
4	14	0.15	38	6.9	0.3	2	23	256	277	255	277	0.89
5	14	7.1e-07	0.00018	23.6	0.6	2	23	291	312	290	312	0.97
6	14	0.0019	0.5	12.8	2.8	1	23	318	341	318	341	0.96
7	14	0.39	1e+02	5.5	2.5	3	21	353	371	352	373	0.92
8	14	0.018	4.7	9.7	1.4	3	23	385	406	383	406	0.90
9	14	6.8e-05	0.018	17.4	3.6	2	23	414	435	414	435	0.98
10	14	9.6e-05	0.025	16.9	3.7	1	23	441	463	441	463	0.98
11	14	3.5e-07	9e-05	24.6	0.6	2	23	469	490	468	490	0.98
12	14	0.0013	0.34	13.3	3.2	1	23	496	518	496	518	0.98
13	14	0.0015	0.39	13.1	1.1	1	23	523	545	523	545	0.96
14	14	9.7e-05	0.025	16.9	1.9	1	23	550	573	550	573	0.97

Sequence Information

Coding Sequence: ATGAATGATTCAACTTACTTGGAATGTTTCAATTATTGCACAAATCTGAATGTTGTACTTCAAGATGAACTTCCAAAAACAATTTGTATTTCTTGTGGCGAATCATTACAAACAGCATATGATTTTATAAAAGCTGCAAAGGAAGCTGATAATTTCCTTCGTGAAAATTTTAATCCTGATCTCAAGAATGAGCCACTTTCAGTggaatcccattccaaagtACCAAACGTTTTTGGTTCTTATCAAATGAAACATGAAGTAgaagaaatttgttttgaagaCGTAGAGCAAACAGATACACGCCCCACATTTGAAGTTATTTTCCATGATGAAATACCCAAAGACCATAATGTGGTCAACGATTTGCCGCCATATCAAAAGGATATTCTGGCCGATGATAACTTgaaactaaacaaaattaccaTTGAGAATGGAGGAGTGATTGAAGATAGTATGGACAGCACGGACAATGTGACACAAGAAGATATCAAGCTCTTTAGATGCACGAAATGCAAGGAGGCTTTCGTGAAAGCAAGAGACTTGAATGACCACGTATCAGAAGTTCATAATTACGTAAACATCGATCCAAAAATTAATTTGCTTTGTAGATTGTGTGGAGAAACGTTTTTAAACCGAGCAACCCTTACTAGACATAAAATCAACGATCACAAAGACAAGGATAAAGGCTTGTGCATCAAATGCAACCAATCATTTAATGATGAAAATAGTCTGCGAAAACACGTTCAAGAAAAACACTCTCAAGTTGAATGTGAATATTGCAATGAAACATTCCCAGCTATAAGAATTAAAAAACACATAAGGAATAAGCATTGCGATTTACTTCTCTCTATCACAAACACGAACAACTTAACTTGTAAATATTGTCCAAAGGTCTTTACCAGTGAAAGTTCCCTACAGGAACATGAAAACACACATACAGGTTTACGACCTTATACGTGTGAAATTTGTGGAAAAGGTTTTCATGCTAAAAAGAACCATACAACTCACATGCGAGCGATCCATGATAACGAGCATGAACTTGACGAACCTCGGGCATGTACAAAATGCGACTTCACCACAACCAACAGATGGTCATGGATCAAACATGCTAAATGCCACGCTAAACCAAAGATTAATATAAAGAGACACCTCTGTTCATTTTGCCcaaTGACATTCTTTTCTCCCAAATACCTCAGAGAGCATGAAAGCTACGCGCATGGTGATAAAGAAAGTGCTCCTCAGTGTGAAATTTGTAAACGAAAATTTGCAAATAGTGTTTGTTTGAAAACTCACATGACTACACATTCTGATGAGCGTAAATATAAATGCAAAGAATGTCCCAAAACATTTAAATTCATGTGTACATTGAACGCTCATGAAAAAATACACAAAGGCAAGGACGTTCAATGTCCGCATTGTGATAAAAAGTATGTAACACCTGCTGACTTAAGAGTTCATCTCAGGAAGCATACTGGCGAACAGCCGTTTGAATGTCACTTGTGCGACAAAAAGTTTGCTATCAGAGTGAGGCTGACTTATCATTTGAAAAAGCACGAAGGAGTGCTATACAAATGCACTCGTTGTCCACAAGAATTCAGCTCCATTGCAAAACTACGTGTTCATACCTTCCAACACATTGGCTACCCGTATATTTGTGATCATTGTGAAATGGGATACGAAAGAAAAAGAGGCTTGTTTCGCCATATGAAGAGGGAACACAAAATAGTCATGACTGAAGAAGATTTAAAACAGAACCACTTAAAAAATTCCTCTAAATATTACAGACCCCAAGAAGAGCCATTCGAAGTCGAAGAAGAAATTACAGGAGTGTAA
Protein Sequence: MNDSTYLECFNYCTNLNVVLQDELPKTICISCGESLQTAYDFIKAAKEADNFLRENFNPDLKNEPLSVESHSKVPNVFGSYQMKHEVEEICFEDVEQTDTRPTFEVIFHDEIPKDHNVVNDLPPYQKDILADDNLKLNKITIENGGVIEDSMDSTDNVTQEDIKLFRCTKCKEAFVKARDLNDHVSEVHNYVNIDPKINLLCRLCGETFLNRATLTRHKINDHKDKDKGLCIKCNQSFNDENSLRKHVQEKHSQVECEYCNETFPAIRIKKHIRNKHCDLLLSITNTNNLTCKYCPKVFTSESSLQEHENTHTGLRPYTCEICGKGFHAKKNHTTHMRAIHDNEHELDEPRACTKCDFTTTNRWSWIKHAKCHAKPKINIKRHLCSFCPMTFFSPKYLREHESYAHGDKESAPQCEICKRKFANSVCLKTHMTTHSDERKYKCKECPKTFKFMCTLNAHEKIHKGKDVQCPHCDKKYVTPADLRVHLRKHTGEQPFECHLCDKKFAIRVRLTYHLKKHEGVLYKCTRCPQEFSSIAKLRVHTFQHIGYPYICDHCEMGYERKRGLFRHMKREHKIVMTEEDLKQNHLKNSSKYYRPQEEPFEVEEEITGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00976756;
90% Identity: iTF_00976756;
80% Identity: -