Msca043260.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Melanostoma scalare
Gene Symbol
ham
Assembly
GCA_949752695.1
Location
OX456986.1:1174604-1206965[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.17 44 6.7 0.1 2 21 278 297 277 300 0.87
2 9 0.0072 1.9 11.0 0.4 1 23 307 330 307 330 0.93
3 9 1.1e-07 2.8e-05 26.2 2.4 1 23 336 358 336 359 0.96
4 9 1.4e-06 0.00037 22.7 1.7 1 23 365 387 365 387 0.95
5 9 3.6e-05 0.0092 18.3 5.0 1 23 393 415 393 415 0.99
6 9 0.00017 0.043 16.2 1.1 2 21 423 442 422 443 0.95
7 9 5.6e-09 1.5e-06 30.2 1.3 1 23 838 860 838 860 0.99
8 9 3e-07 7.7e-05 24.8 0.9 1 23 866 889 866 889 0.97
9 9 5.1e-05 0.013 17.8 6.6 1 23 895 917 895 917 0.98

Sequence Information

Coding Sequence
ATGCAGTCTTGCTTCAATGGCCACAATATTCTCCGGATCTCAATATCTATAGCAACGTGTGGGAGCAGTGGTGATGAGTTCGAACCGATTAATCGCCACAACTCACATAGTCTAAGTCAACAGGCCGAAGAGCACGAATTGCAAGACTATCGGCGATACGCAAGTGCGCCAAATATATCCGCAAATCCCATGGATCAAATTTATAACAGCGCCGCTCTGCATGAGCGATCCGCGGAACGTTTCCTTTCGGAGATGGCTCGTTTGCAGGAACCCATATGTGATTTAGACATACGCGATAACGGCGTGTATGCCAAGGTCGTCCTCAGGAGAGGTACAAGGTTTGGACCGTTTGCTGTGAAATTGTGCAATGAGCCCACCGACCGGAAGCTAGCCTGGGAGgtaaTGGCAAGTGCTCACTTTCGAGGATGGCTAGAACCAGTACCCGAAGTATCAACATGGCTAAGAAAAATTCGCTCAGTTAACAATGCCAAAGAAGCTAATCTACATAATTTTATAGTCGAAGGATACCTATGGTACGAAGCAGTACGGGACATTCCAGCCGGCGAAGAAATTGCCGTGGATTCAGATTCGAAGAGCCTGCTGCATTTAAATGACATTTTCACAGGCACTGGTTTCAATGTCGACGACCGAAGTGAGAAGGAAAATGgaTCTCAATACAGTGGAAACACAACTGGTGATGACGAGTTTAATAATTCGTCCAACGATCAGGACAACAACATAAAAAGTGAGAATAATAACCGAAACGCTGAGAAAAGTGATAAAATACCCGGAGATCACCCGGATACTGACGACGAGAACGGTATAGACATACGCTGTGAAGTTTGTGACAAGCCCTACCACGATTTAGATCGATTGGACGAGCATTTGGTTGCTGCACATCATTACCGCAAGGACGAATACAGCTGTGATTTGTGTGTTAAGAACTATTCGTATCGGCCGTCGTTATTAAAACATCGTGCACTAGTTCATAACGATATTAGGAAATATCCTTGTGAAAACTGCACCAAGgttttttgtgATCCGTCAAATCTTCAAAGACATATTCGTGCCCACCACGTCGGCGCTAGAAGTCACGCGTGTCCCGAGTGCGGTAAGACTTTTGCTACATCGTCTGGCTTGAAGCAACATACGCACATTCATTCATCGGTTAAGCCATTCCAGTGTGAAGTGTGTTTTAAGGCGTACACGCAATTTTCGAACCTGTGTCGTCACAAGCGCATGCACGCCGATTGTCGCATGCAAATTAAATGCAATAAGTGCGGTCAGAGTTTCAGCACGGTGACGTCGCTTTCAAAGCATAAACGGTTTTGTGATTCAACAACAGTGGCACCACCTACAGGCATCCCAGCTCATCatcatccacatccacatcatTCGCACATGCATCACCAGCCCGTTTCCAGTCATTCCAGTCAACGAGGCCTACAATCTAACGGCATTCCACCAGCCATGAATACACCACCAAATCCTTTCTTCATGTTCCGAGGACCACCATCCTTTTTCTCGCCTGGATTTCCTTCCTACGGACTACCGGGAATGTTCCCACCGAGTCCAGCACCAGCTTCGAACTTCCCACTTCTGTTTTCGAAGCCAGCGGTGGACATTGCGATCCCGAAGAAAGAGCCAACAACACCACCCATGAGACATTTAAACCAACGCAGCAATTCAATGGATAAAAGCTTTTTCCCGCAGACAATGTATCATATGGAAAACGATGATATCAAGCCTGTAGCCATCCCATCACAGAAATCGCCTGAAACCGGAAAGCTACACATTCATTCACCATCACCACGGAGTAACCACTCACGGCTTTCTGACGAGGAAACGAGTTTCTCTCTAATAGAAGCAAGGCCCAGTGAAGCTGAAGTTAAAAATGAAGAGTCAGAGCCCCAACAGGAACAAGAGGATGTAGATTCCAGTGATGATAAGAAACACATCAACGTAACTACCCCCTCTCCGCCGGTCCCGGAAGAAGCGTCCACATCAAATGGCGAACAACCACTTGATTTATCGTTAGGACGGAAACGGAAGCACACGGAGGAACCCATCAATGAACAAATAATTCCTGAAACTCCTAAAAATGTAGAAATCGAAGACACTGCGCCTGTTAAAAAACGTCCATTGCCTGAGGAAGCCCCTCAGCAGCAGCAGTCATACCAGGTGAACAGTCCTGCCCCATCGGTTTCACCAGGGCCAACGCCATCACCGTCTCCTCCAAATAACGGACCAGCTGCAATGGCATGCCCACGACCGATTCACCCAATGCTGATGGCTTTCTACAGTCAGGCTCGACAACCCGGTTTGGGAGTTGCAGCAGATTTTTCTCGACCATTTCCTTTTTTAGGACCAATGGGCGGACGGCCAACTTTTGACCATTTGCTTCATCGTAATGGACCGTTTCCGCCCAAACCCACATTTCATGAAGCCTTGATGGCTGCTGGAGGAATGTCAGGCGGATTAACAGCTGCCCCAGGTAAAATCAAAGACCGATACACATGTAAATTCTGTGGTAAGGTCTTTCCAAGGTCGGCAAACCTTACCCGACACTTACGCACACACACCGGTGAACAACCATACACCTGCAAATACTGCGATCGCGCCTTCAGTATTTCAAGTAATCTGCAACGGCATGTTCGCAACATTCATAACAAGGAACGACCTTTCCGTTGCCATCTTTGTGACCGTTGCTTCGGACAGCAAACAAATTTGGACAGACATTTAAAGAAACACGAAGCTGATACATCAGGACTCGGCATCGGTTTAGGAGATTCCCCATCGTCTAATGAAGCAGACCGTGAGGACTCCTACTTCGACGAAATACGATCTTTTATGGGACAGGTAACATACAATGAGGACTTGTACACCCCCACGAGCATTGGAAACGGAGAAAACGATACCGAATGCAGTAGCGATGTTGAAAACGACATAACGCCCAACAGTACCAAAGACACAATGAACAACAATGACGCCGCCATCGAAGTCACCACATAA
Protein Sequence
MQSCFNGHNILRISISIATCGSSGDEFEPINRHNSHSLSQQAEEHELQDYRRYASAPNISANPMDQIYNSAALHERSAERFLSEMARLQEPICDLDIRDNGVYAKVVLRRGTRFGPFAVKLCNEPTDRKLAWEVMASAHFRGWLEPVPEVSTWLRKIRSVNNAKEANLHNFIVEGYLWYEAVRDIPAGEEIAVDSDSKSLLHLNDIFTGTGFNVDDRSEKENGSQYSGNTTGDDEFNNSSNDQDNNIKSENNNRNAEKSDKIPGDHPDTDDENGIDIRCEVCDKPYHDLDRLDEHLVAAHHYRKDEYSCDLCVKNYSYRPSLLKHRALVHNDIRKYPCENCTKVFCDPSNLQRHIRAHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCNKCGQSFSTVTSLSKHKRFCDSTTVAPPTGIPAHHHPHPHHSHMHHQPVSSHSSQRGLQSNGIPPAMNTPPNPFFMFRGPPSFFSPGFPSYGLPGMFPPSPAPASNFPLLFSKPAVDIAIPKKEPTTPPMRHLNQRSNSMDKSFFPQTMYHMENDDIKPVAIPSQKSPETGKLHIHSPSPRSNHSRLSDEETSFSLIEARPSEAEVKNEESEPQQEQEDVDSSDDKKHINVTTPSPPVPEEASTSNGEQPLDLSLGRKRKHTEEPINEQIIPETPKNVEIEDTAPVKKRPLPEEAPQQQQSYQVNSPAPSVSPGPTPSPSPPNNGPAAMACPRPIHPMLMAFYSQARQPGLGVAADFSRPFPFLGPMGGRPTFDHLLHRNGPFPPKPTFHEALMAAGGMSGGLTAAPGKIKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHLCDRCFGQQTNLDRHLKKHEADTSGLGIGLGDSPSSNEADREDSYFDEIRSFMGQVTYNEDLYTPTSIGNGENDTECSSDVENDITPNSTKDTMNNNDAAIEVTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01541612;
90% Identity
-
80% Identity
-