Basic Information

Insect: Melanophora roralis
Gene Symbol: zfh1
Assembly: GCA_963583895.1
Location: OY757187.1:22440734-22445586[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00014 0.016 16.7 0.7 1 23 195 217 195 217 0.95

2 15 0.045 4.9 8.8 1.2 3 23 225 245 223 245 0.95

3 15 0.00025 0.028 15.9 0.5 1 23 419 441 419 441 0.98

4 15 0.01 1.1 10.8 0.7 1 23 447 469 447 469 0.98

5 15 1.6e-05 0.0018 19.6 3.9 1 23 501 523 501 523 0.98

6 15 0.012 1.3 10.6 0.3 1 23 544 566 544 566 0.94

7 15 0.027 2.9 9.5 0.1 1 23 572 595 572 595 0.95

8 15 0.39 42 5.9 0.4 5 19 606 620 603 621 0.91

9 15 6e-05 0.0065 17.9 5.6 1 23 630 652 630 652 0.97

10 15 0.052 5.6 8.6 1.7 2 23 658 679 657 679 0.97

11 15 7.3e-05 0.0079 17.6 0.2 1 23 688 710 688 710 0.98

12 15 0.0069 0.75 11.4 0.2 3 23 718 738 716 738 0.97

13 15 0.00047 0.051 15.1 0.5 3 23 746 766 744 767 0.95

14 15 0.0038 0.41 12.2 0.1 1 23 777 799 777 799 0.96

15 15 0.02 2.2 9.9 0.0 1 20 1379 1398 1379 1401 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00014	0.016	16.7	0.7	1	23	195	217	195	217	0.95
2	15	0.045	4.9	8.8	1.2	3	23	225	245	223	245	0.95
3	15	0.00025	0.028	15.9	0.5	1	23	419	441	419	441	0.98
4	15	0.01	1.1	10.8	0.7	1	23	447	469	447	469	0.98
5	15	1.6e-05	0.0018	19.6	3.9	1	23	501	523	501	523	0.98
6	15	0.012	1.3	10.6	0.3	1	23	544	566	544	566	0.94
7	15	0.027	2.9	9.5	0.1	1	23	572	595	572	595	0.95
8	15	0.39	42	5.9	0.4	5	19	606	620	603	621	0.91
9	15	6e-05	0.0065	17.9	5.6	1	23	630	652	630	652	0.97
10	15	0.052	5.6	8.6	1.7	2	23	658	679	657	679	0.97
11	15	7.3e-05	0.0079	17.6	0.2	1	23	688	710	688	710	0.98
12	15	0.0069	0.75	11.4	0.2	3	23	718	738	716	738	0.97
13	15	0.00047	0.051	15.1	0.5	3	23	746	766	744	767	0.95
14	15	0.0038	0.41	12.2	0.1	1	23	777	799	777	799	0.96
15	15	0.02	2.2	9.9	0.0	1	20	1379	1398	1379	1401	0.93

Sequence Information

Coding Sequence: atggaTAATCATAGCTATGGTGGCATACAGTGGATACAACACCACTTGGGAAATCACTCCTCCCATAGTGGAGATATGAAAACTGCTGGTCAGTTACTTATCGATCCTCAGCCACCGCGTGCCGAGGATCTTATGGCTACTGGTAATTCTTCATCAGACTACTTGACCACAGAGAATGAAACTGATTCGGCAACTATTGCTCAAATAGCAGCGGAAAATCTAATATTTATGGCTCGTGATGGACAAATGATGACGCAAATTATAACTCCCGGAGAAAATGGAGCAATGGTTGTAACTGCCAGCGACGGCGAACAAATTGATTGTGATACAATTATGGAACAGTCTGCTTTAATACAACGACACGAAGATGCCGGTGGTGGGGTTTATAATGTTGGACATTTTAACGAAAACACACCTCAAATGGTGACTGAAGAAATTATTACCGACGACTGGGTGCAACATCAGGGAGAAGAAAGggtCGAAATACCTGCAGAACAAATAATAGGCTCTAGTAGTCAGGTATTGCTTGATATGGAAGTTCCCCTGCCAACAGTACAAGATGAATACACTGCCCTTAGACCGTATCCCTGTGATTTTTGTAGTCGTCGTTTTCGTAAAAAAGCCAGCTTAATGAATCATATGGTAGCACATCAAACCGATAGGCCACACTTGTGTAAACTATGTGGGGCTAGATTTCTAAGGCGTCAAGATctcataaatcatttaaaagctCACGCCGAAGAACCGTCTGAACCGCAAATAGATGACAGTGATTTTATACACTTTGTTAACGATACTGCTTCAACATCACAACGTACTACAAATGATCATTACTATGACCAGGACTGGTGTGTGCCAGAAGATTCTGTAACTATACCAACAAAGTCTAGTCGTAAATATCAGCAACAAATTACCTCTATTTCTAATCGACAATTTATGATGGAAAATATGATAACAGCATCTTCAGCGGGCGCATTAGTTACAACACCAACTATAACAACAGCGGTTCCATCTAGAGGGCGTATAAGTCGTCTTAAGCCTAAAGAGGATAATTCATATGTAGTGGAAGCAGGCAACAATTGCAGCTCAAATGAAATGATAATTTCATCGGCTTATAGCATCGTAGAATGTGATAACTTATCCCCAAATACGTCTACAGAAACGAGTAAACTGCCCCAGGATAATGCACCCGCTTTAAGAGAATATGTGGAACAAAAAGTCTTACGCTATCCCGTTATTGATGAGAGTAAGCCATTTGTTTGTCAACAATGTGGCCTGGCATTTTCCAGGGAAAAAGCAATGTTGTCACATACAAAGACGCATCGCAATGATTCCCCCTTTGAGTGCACGCAATGCAATGAGTTATTTTGGGATCAAAATAGTTTGCAGGAACACCAGAAATCCCATCAGTTTGAAGATAGTAATTCTGAGTATGATCCCAATGAGGGGGAGGATGAAACACAAACCGAATCCGAGTCTGAGCAACAACTATACGGGGAATTCTATTGCAGTGAATGCGGCATGTCGTTTCATCGTCAGGATCTTCTAAAACGACATACAAAATCTCATCCAAAATTTTATGCGGCTGCGACACAATCCAACATTAATGACTTAGAGTCTAGGGGGCAACATTGTTGCAACACATGTGGAGAAACATTTGCTGAAGCTTTAGATCTGTTAGCGCATGCTGAAATACATGCGCGATACCCGCCctttaaATGTGTCTTATGCGGTGAATCCTTTTTCGAAGAACCCACTATCAAGAAACATATTCAAGCCCTGCATTCTAATGAACTAACAGAAAATTCCTGCATCTTGTGTGGCAAAGAGTGTCGTGATCGCAAGGCTTTAATGAAACATGCTTGGGATCATTCAAGGGAAAAATGTCACTCCTGCTCTAAATGTGGTAAAAGTTTTCACAACAAAGCTCGTCTTAAACGGCACATGGCATCACATCGTGACAAGTCCGTACAGTGCGATGTTTGCCACGAAGAGTTTCCTGACGGACGTACTTTGTCCAATCATCGCCATTCTCACAGTGCTACTTCGGCAGGCAAATTATTTCCCTGTCTAgaatgtggaaaaacttttggcTCCCGTAGCTCTCAACAGATACATGTTCGCATACACACCGGAGAAAGACCGTATGGCTGTCGTTTTTGTTGGAAGGCCTTTGCCGATGGTGGTACTCTGCGTAAACATGAGCGTATACACACGGGAGAGAAGCCGTATGGCTGCTCCGTTTGTCCACGTGCGTTTAATCAACGTGTAGTTTTAAGGGAACATATACGTTCACATCATTCAGGTTTGGATGCCAAGAGAGGCACCTATTTTTGTACGGTTTGTGGTGCTGATTTGTCGTCATCAGgtgatttaataaaacatttaattcaaCACAGTGATATGAACACGGCTATGCAAAGGCAACCAGTGACTGGACCTCGAAAATATAAACGACGTCGTAAACTGAGGCCGCATGAATTGGCTCGTCTCAAGCTTGAAAACAGGCATAACGGGGGTAATGGCAGTGATATTGATTTATCCGATTTTGACATTGACAATGTTGATGATTTGCTCGCTATGACAACAGATAGCAATACAGCGAATGATAcggtaacaacaacaattactgCCCATGAAGCTGCAACAGTTTCTCTGCCTGTAAGATCGACAAAAAGGAAACGTTCTCACTCAAATACACTCGCAGAAAGCAATATTAAAAGTGAAGCAACAACAAATAAGTCGAAAAGAACACATAAGGATGAGGTACATGATTTTGACATAGATGTGGGTATAAACGAGAATGAGCTTAAGAAAGGACGTTGTAACACCAGCAAAAGTGATAAAGACTTGGCAGCAAAACAAACTGAAGACAGTTATAAAACATTGTTATCCAATTTAGAAACAACTCTACAAAGTATAGACACTTTAGTGGTGGGACCgcctgaaaataaaattattgatccgcagcaaaaacaaacaaaacgcAAAATTAAACAGGAGTCGACGTCTACAGCTCAAAGGACACAGCAGGTACAATTGACAAGATTAGATAAGGAAGCGGCAGCTAGCACAAATGGCAGAGGTCGCAAAAGTAAGACAGCAGCTACTAAACAGTCTAAAGGGCCACATATGATTCACACTGAAAAATCGATTATAGTAAATGATAGTGGCGGATCCggaaacaaaaagaaatcaaaatccATTATTACACGCAAACACACAACAAACGTTGATTTACTGCCTAAAACCTCAACCATAGTTGATGATTATGATATTATCTCACCTGCCTTGCAACCACCTAAACAAATTAGCTCTAGTCCTTTGCACATAAAACAGGAACAAGAAAATCGCATCGTtcgcaataaaaattatcaacaaataaacaatacaCAGCAGcataatttaatgaaaactaACAACAAGGCAAATGACAACACATGTACAACACGGAGCCAGTCAATCTCCCGCCAAACAACCAATAATGATCTCTATGATGCTCACTTATTGTTGGAGGCCTCATGTCTACGCAATGACTTAGATGATTTTCTCAGATCTCCCTCAAAGCTAGATAAATCGAGGCAACGTTTTACCAGTGAATCTTCGACACAATTTTTGGCCGAACAATCAGAGGAGGaccaacatttaattaaaattgaaccAACTTCGCCAGATTTAAGAGAAATTGTTAACGGTGTAGGTTTAGTTAATACGGCCACTACCCAAGCTGAACTAGAACTGGAAGTTAACTCCACCAAAAATCGTAGATCAAACAAATCCCGTTCCCAAAAGGTAGTTAATTCAACACGTAAATACTTAGAATTTGGCGGTGATATCACAAGTAACGATGCAATTTCTATTGGCGTTAAGAAAACAATTACATCAAAGTCAAAATCTGCCCGCACTGAACAAGCTAAAACCTCAAAATTTGCACAAAGTACTGATTCACCCACGTCTTATTTAGATTACAGTATAGTGGATACATTTAATACGGTCACAAGTTCGCCGGCGAATAACAATTCGTTTGCCTCTATCTCGGCAGTGGTTTCAGCAGCTGTTGCTTCTGCCGCGGCCCAACAAAACTCCAATGCTGCCGCTACTGCAGCTACGGCAGTGCAAAAACCTCAACGCTTTTTTGAGTGTGAAATGTGTAGCGCTATATTTTCGGATCGTGCTCAACTTTTGGATCATGTAcccatacatatttaa
Protein Sequence: MDNHSYGGIQWIQHHLGNHSSHSGDMKTAGQLLIDPQPPRAEDLMATGNSSSDYLTTENETDSATIAQIAAENLIFMARDGQMMTQIITPGENGAMVVTASDGEQIDCDTIMEQSALIQRHEDAGGGVYNVGHFNENTPQMVTEEIITDDWVQHQGEERVEIPAEQIIGSSSQVLLDMEVPLPTVQDEYTALRPYPCDFCSRRFRKKASLMNHMVAHQTDRPHLCKLCGARFLRRQDLINHLKAHAEEPSEPQIDDSDFIHFVNDTASTSQRTTNDHYYDQDWCVPEDSVTIPTKSSRKYQQQITSISNRQFMMENMITASSAGALVTTPTITTAVPSRGRISRLKPKEDNSYVVEAGNNCSSNEMIISSAYSIVECDNLSPNTSTETSKLPQDNAPALREYVEQKVLRYPVIDESKPFVCQQCGLAFSREKAMLSHTKTHRNDSPFECTQCNELFWDQNSLQEHQKSHQFEDSNSEYDPNEGEDETQTESESEQQLYGEFYCSECGMSFHRQDLLKRHTKSHPKFYAAATQSNINDLESRGQHCCNTCGETFAEALDLLAHAEIHARYPPFKCVLCGESFFEEPTIKKHIQALHSNELTENSCILCGKECRDRKALMKHAWDHSREKCHSCSKCGKSFHNKARLKRHMASHRDKSVQCDVCHEEFPDGRTLSNHRHSHSATSAGKLFPCLECGKTFGSRSSQQIHVRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCSVCPRAFNQRVVLREHIRSHHSGLDAKRGTYFCTVCGADLSSSGDLIKHLIQHSDMNTAMQRQPVTGPRKYKRRRKLRPHELARLKLENRHNGGNGSDIDLSDFDIDNVDDLLAMTTDSNTANDTVTTTITAHEAATVSLPVRSTKRKRSHSNTLAESNIKSEATTNKSKRTHKDEVHDFDIDVGINENELKKGRCNTSKSDKDLAAKQTEDSYKTLLSNLETTLQSIDTLVVGPPENKIIDPQQKQTKRKIKQESTSTAQRTQQVQLTRLDKEAAASTNGRGRKSKTAATKQSKGPHMIHTEKSIIVNDSGGSGNKKKSKSIITRKHTTNVDLLPKTSTIVDDYDIISPALQPPKQISSSPLHIKQEQENRIVRNKNYQQINNTQQHNLMKTNNKANDNTCTTRSQSISRQTTNNDLYDAHLLLEASCLRNDLDDFLRSPSKLDKSRQRFTSESSTQFLAEQSEEDQHLIKIEPTSPDLREIVNGVGLVNTATTQAELELEVNSTKNRRSNKSRSQKVVNSTRKYLEFGGDITSNDAISIGVKKTITSKSKSARTEQAKTSKFAQSTDSPTSYLDYSIVDTFNTVTSSPANNNSFASISAVVSAAVASAAAQQNSNAAATAATAVQKPQRFFECEMCSAIFSDRAQLLDHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00259092;
90% Identity: -
80% Identity: -