Mqua058607.1
Basic Information
- Insect
- Melangyna quadrimaculata
- Gene Symbol
- grau
- Assembly
- GCA_949320155.1
- Location
- OX439485.1:48602896-48636957[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.085 22 7.8 0.2 2 23 246 268 245 268 0.95 2 18 0.00012 0.031 16.8 2.7 1 23 300 323 300 323 0.97 3 18 0.012 3.2 10.5 0.6 1 23 331 353 331 353 0.98 4 18 3.4e-07 8.9e-05 24.8 0.8 1 23 361 384 361 384 0.97 5 18 0.00039 0.1 15.2 1.2 3 23 392 412 391 412 0.96 6 18 0.052 13 8.5 0.4 2 23 421 443 420 443 0.95 7 18 4.7e-05 0.012 18.1 2.5 1 23 448 471 448 471 0.95 8 18 0.0001 0.027 17.0 1.5 1 23 477 499 477 499 0.98 9 18 0.0001 0.026 17.0 0.6 1 20 505 524 505 526 0.96 10 18 0.0013 0.35 13.5 0.3 2 23 667 689 666 689 0.95 11 18 6.2e-05 0.016 17.7 2.3 1 23 721 744 721 744 0.90 12 18 0.011 2.8 10.6 3.4 1 23 752 774 752 774 0.91 13 18 2e-05 0.0053 19.2 0.7 1 23 779 802 779 802 0.96 14 18 0.52 1.4e+02 5.3 0.1 3 23 810 830 809 830 0.95 15 18 0.031 8.1 9.2 0.9 2 23 839 861 838 861 0.95 16 18 0.00033 0.087 15.4 1.4 1 23 866 889 866 889 0.95 17 18 0.00028 0.072 15.6 3.0 1 23 895 917 895 917 0.97 18 18 0.002 0.52 12.9 5.3 1 23 923 946 923 946 0.98
Sequence Information
- Coding Sequence
- ATGGTTTGTCGATTGTGTTTAAATAAAGACGATGGAAGTATTGTAATATTTGGCGAAGAAAAAATCCAAAAGTATATAACAAAATTCTTGCAGTTAGAGCTTTTGCCAGATGATCCAGTTTCGAAAGTAATATGTACTATTTGTTGGCAACAATTAGATAATTTTCAAAAGTTCTGCTTGCAAATAGAGGAAGcccaaaaatcacttaaaacattGGCATTGGCAGACGATTCAGTTCAACAAGCTAAAACATATTTTGTTAAAGATATAAGTCCTGTGAAAGAAGAAGATCCAGCGGAAGAATCGAATGagGATGCCTGCGATAACGACGATACACTGGCCTGCCTTGATGAGGACCTCCTAAAATTGGAACAAAACTCTGATCAAGAAAATGATCTACTAAGAACTGTTACCTTTGATccaatttttgaagaaattccAACACGAATGCtaagagaaaaaagaaaatcaaatgtaaatgaaaaaaatgaagattCTGAATCAACTGATGATGAAGAAGAAGAGGAATACAaagcagaagaagaagaagacgaagaggaatacaaagaaaaacaacCTAAAAGAAAAAGAGTTGCAAAGAGGAAACGCGACCGATCCAATGAGGATGAACAAAATACGCCAGGCGAGAATAAAAGAGTGAGAAAAAAGAAACTTTCGAAAGCTATGCTGCTCTCTAGGGAACAAGATGAAATCATCAAGAAGTATATGAAACTAACGTGCGATATTTGTTCGATAGACCTTTCTGATTTTAATGACTTGCAAAATCACTTCCGACTCATTCACAACCGCACAGGATATGCtgtttgttgcaaaaaaaaacttaaaaatcgtGGCCTAACTGTCGATCATATTAACGGGCATAACGACCCTGACTATTTCAAatGCCCAGAATGTGGTAAAGTTGTGTCTGATAGATTTTGCATGCAAAGACACAAGCTTACGTTTCACCCAACCGAAGAACTTAAAACATTTCAATGTTCTTACTGTTCTGAAAAACTGGCCTCTCAATATCTGCTAGATTTGCATACTATAAAACATGTTCCAGAGGATAAATGCACTTTCATTTGTAAGGATTGTGGAAAAGGATTCCCAACAAACTCAACTCTTAATAGTCATATAAAACGGAAACATTCAACAGCATACGACAGAATGTGTGAAATCTGCGCTAAACTATTTCGGCATAAATCAGCTTTTGAACGTCACATGGAAGAACATCAGGGTATTGTTCATCCTCAGGTACAATGTAACATATGTGGCTCATGGTTGAAGGACATGTCAAGTCTTAAAAAACACATAAACAATAAACATGATGATAAAACACATATCTGTAATATCTGCGGCAAACATTCAACCTCCAAGAGTGCTCTTCAAAGTCACATTAATTATATGCATGAAATACAGCCTGTATTTAAATgctcattttgtgaaaaatcgttCAAAAAAGCTATTAAACTGAAGgaACACGTGGCAACTCACACTGGAGTAGTTCTCTACACATGCCCGTATTGTCCAACAAAGTTTAATGCTAAGTCTAATCTGCATTCGCATCAAGATGCTTACGATAACGTTGACATGCTGCAATGCCTGGatgaagaaatattaaaagttgaATTGATGATTGGAGAGGAAAAAAATGATGTATCAGTACCGGCGACAAATAACTCGTCTGAAACAAACAAAGCTCTTCCAACACGAAGAGTTACCCGTTCAACTTTAAAAAACTTAGATCATACTTCTAGCCCTCCCaaagtaataaaagaaaaaagaaagcaaGAAATTAAAGAGCACGAGTCTTCTGAAGACGAAACAGAAACTCCTTATATTGCAAATAGTGACCAAATTGCTAAAAGAAACATTCGATCCAAGAAGGCTGAGCAAAATATTCAAGAGAATAAAGATGTTAGATCTGAAAAGTtcttgaaaaatatgaaaacaacaaaagaaaacgATGCATTCATACAAAAACATATGAAACTATCGTGCGATATTTGTTCTATAAGTTTTCCCGACTTTACAAagctaaaaaatcattttcgtgTAGCTCATCAACGCAGAGGATATGTAGTATGTTGCAATAGGCAGCTGAAAAAACGTGGTCTGATTGTAGATCATATTTACGTGCACAATGATCCTGAGTATTTCAAATGCACTGAGTGTGGTAAAGTTCTGTCCGATAGATCCTGCCTACAAAGACACAATATTCTATTCCACCAAGCCGAAGAACtaaaaacctttctatgtagTCATTGCCCTAAAAGATTTCCCACACAAAAACTGCTCGATCTGCATACAGTCCATCACAATGAATGCACTTTCATGTGTAGCGAATGTGGAAAAGGattcccaACAAAATCAACAATGAATGTCCATTTTAAACGAATCCACTCGACATTGTGCGACAGAATGTGTGAAATCTGCGCAAAACTTATCAAAGGCAAAACAGCTTTTGAGCGTCACATGGAAGAGCATGAAGGAATTGTTCAGCCTAGAGTGCAATGTAAAATTTGTGGATCATGGTTGAAGGATAAGAACAGTCTTCGGAAGCACATGTACAGCAAACACGATGGTAAATCACATGACTGTAAAATTTGTGGCAAAAATACACCATCATATAGTGCTTTGTATAGTCATATGAAGTATATGCATGAATTATCGGCCATGTTTCATTGCACATTTTGTGATAAGTCGTTTAAAAAAGCTATTAAACTGAAGGAACACGTGGCAACACACACTGGAGGTTTTCTCTACACATGCCCACATTGTCCAACAACGTTTAATGCAAAAACAAATATGCATTCTCACCGAAAAAAAATGCATCGAGAAGAATGGGAGGCAAATAGGCGTTATGCCAAAAAAACGCCAACAGTTGAAGGAATCTCAAACATAGAAAGCTTGGATGCATTACACtga
- Protein Sequence
- MVCRLCLNKDDGSIVIFGEEKIQKYITKFLQLELLPDDPVSKVICTICWQQLDNFQKFCLQIEEAQKSLKTLALADDSVQQAKTYFVKDISPVKEEDPAEESNEDACDNDDTLACLDEDLLKLEQNSDQENDLLRTVTFDPIFEEIPTRMLREKRKSNVNEKNEDSESTDDEEEEEYKAEEEEDEEEYKEKQPKRKRVAKRKRDRSNEDEQNTPGENKRVRKKKLSKAMLLSREQDEIIKKYMKLTCDICSIDLSDFNDLQNHFRLIHNRTGYAVCCKKKLKNRGLTVDHINGHNDPDYFKCPECGKVVSDRFCMQRHKLTFHPTEELKTFQCSYCSEKLASQYLLDLHTIKHVPEDKCTFICKDCGKGFPTNSTLNSHIKRKHSTAYDRMCEICAKLFRHKSAFERHMEEHQGIVHPQVQCNICGSWLKDMSSLKKHINNKHDDKTHICNICGKHSTSKSALQSHINYMHEIQPVFKCSFCEKSFKKAIKLKEHVATHTGVVLYTCPYCPTKFNAKSNLHSHQDAYDNVDMLQCLDEEILKVELMIGEEKNDVSVPATNNSSETNKALPTRRVTRSTLKNLDHTSSPPKVIKEKRKQEIKEHESSEDETETPYIANSDQIAKRNIRSKKAEQNIQENKDVRSEKFLKNMKTTKENDAFIQKHMKLSCDICSISFPDFTKLKNHFRVAHQRRGYVVCCNRQLKKRGLIVDHIYVHNDPEYFKCTECGKVLSDRSCLQRHNILFHQAEELKTFLCSHCPKRFPTQKLLDLHTVHHNECTFMCSECGKGFPTKSTMNVHFKRIHSTLCDRMCEICAKLIKGKTAFERHMEEHEGIVQPRVQCKICGSWLKDKNSLRKHMYSKHDGKSHDCKICGKNTPSYSALYSHMKYMHELSAMFHCTFCDKSFKKAIKLKEHVATHTGGFLYTCPHCPTTFNAKTNMHSHRKKMHREEWEANRRYAKKTPTVEGISNIESLDALH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00664274;
- 90% Identity
- -
- 80% Identity
- -