Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: -
Assembly: GCA_949320155.1
Location: OX439484.1:8611763-8615349[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5e-05 0.013 18.0 1.1 2 23 406 427 405 427 0.97

2 16 1.9e-05 0.0048 19.3 1.1 1 23 433 455 433 455 0.98

3 16 0.00032 0.082 15.5 0.1 1 23 461 484 461 484 0.98

4 16 4.8e-05 0.012 18.0 3.5 1 23 499 521 499 521 0.98

5 16 0.00011 0.03 16.9 2.7 1 23 561 583 561 583 0.97

6 16 0.0001 0.026 17.0 1.8 1 23 589 611 589 611 0.98

7 16 1.9e-05 0.0048 19.3 0.6 2 23 723 744 722 744 0.96

8 16 6.4e-06 0.0017 20.8 3.1 1 23 750 772 750 772 0.98

9 16 4.6e-05 0.012 18.1 0.7 1 23 778 801 778 801 0.98

10 16 0.00053 0.14 14.8 1.9 1 23 812 834 812 834 0.98

11 16 1.5e-05 0.0038 19.7 0.5 1 23 847 869 847 869 0.98

12 16 0.023 6 9.6 2.0 1 23 875 897 875 897 0.97

13 16 4e-05 0.01 18.3 0.3 2 23 903 925 902 925 0.96

14 16 1.4 3.5e+02 4.0 0.2 1 23 933 956 933 956 0.89

15 16 0.31 82 6.0 1.9 2 23 965 987 965 987 0.92

16 16 0.00085 0.22 14.1 2.0 2 23 993 1014 992 1014 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5e-05	0.013	18.0	1.1	2	23	406	427	405	427	0.97
2	16	1.9e-05	0.0048	19.3	1.1	1	23	433	455	433	455	0.98
3	16	0.00032	0.082	15.5	0.1	1	23	461	484	461	484	0.98
4	16	4.8e-05	0.012	18.0	3.5	1	23	499	521	499	521	0.98
5	16	0.00011	0.03	16.9	2.7	1	23	561	583	561	583	0.97
6	16	0.0001	0.026	17.0	1.8	1	23	589	611	589	611	0.98
7	16	1.9e-05	0.0048	19.3	0.6	2	23	723	744	722	744	0.96
8	16	6.4e-06	0.0017	20.8	3.1	1	23	750	772	750	772	0.98
9	16	4.6e-05	0.012	18.1	0.7	1	23	778	801	778	801	0.98
10	16	0.00053	0.14	14.8	1.9	1	23	812	834	812	834	0.98
11	16	1.5e-05	0.0038	19.7	0.5	1	23	847	869	847	869	0.98
12	16	0.023	6	9.6	2.0	1	23	875	897	875	897	0.97
13	16	4e-05	0.01	18.3	0.3	2	23	903	925	902	925	0.96
14	16	1.4	3.5e+02	4.0	0.2	1	23	933	956	933	956	0.89
15	16	0.31	82	6.0	1.9	2	23	965	987	965	987	0.92
16	16	0.00085	0.22	14.1	2.0	2	23	993	1014	992	1014	0.97

Sequence Information

Coding Sequence: ATGTCTGTCAAATTGGATGATTCTGTTTGCCGGGTATGTTTAAGTTCATCAGGCAGCATAACAATTTTTGATGATTGTGGCAAAGATGACCAATTTCGTTATTGTACTTCACTGGagGCCTCTAAAAACGATGGCCTCCCTTCGAAACTCTGTAAAAAGTGCAACGACCATCTGAAAGTTGCCTACGATTTTCGTTTCCAAGCTATCTATGCTgagaaatattttcgaaaaactattttcttgCCTTCTTTTAAGAAAGAAGACGATGGGGCCACCAGCAATGGAGATGAGGTCGATAGAAACACAAATAATCATTGCTCCGATGAGCTAGACGAAAATATGGCAGAAATTGATATGCTGCTTGCGATCCATACGGAGAGCGTTGATGATGTCAATGGCCATAATAAAGACGATGATAATAATGATGGTATAATGGACAATACCGAGTTCTTTGATAATGATAGTGTAGATATCGATGAAAAACACGTTGAGATCATTGGGATGGAAACATTCGAAAGGGAAAAACGTGAACAAAAGGAACAGAAAGTAAAGTTAGAGATCGCTAATGTCCCACCTCCACTAGTGTCTATTACAGAACGTAAAACGAGGTTTGAGATGTCATCGGGGGCGATTTCAAGTATACCCTTAAAATCTCCAGAATTGCCAGCGAGCAATATTGTGCAACAAACCCAAGTTAGTTTAGATGAAATTCAGCAGTACCCGGATTCGGGTAGTTTTGCCCATCACACTCAATCTGTTCAAGAAATAACCGTGGAGAATACCAACGGCAGATCTGAGCATCTAGAAATCCATCCTGTCTTGAAGAACGATCCATCTGGGTATGATTTTACTGTTCCCTCAACGGTAGCTGTTGGCTTTGACTCATATTCCACGCCATCACAGATTCAGTTCCAACAAATGCCTCTCCAGATAGAATATGAGCAACAGCATAATTCACTACCCCTACAAGATTCTGTGCACCCAAACTCTGAGAACTATGATTTTCCTTATCAAGAACCATTCTCGACGTATGGAacacaaaataatgaaatagtTCCTCAACAACAACAGGAAAATATTCAACAGtatcaacaacaaaatcaagtCCCCGACGAATTACCCAACAACAACACTTTTAAGACGGAGTATCTAGAAGGGATAGTTGTTGCGAaagcaaagaaaacaaaaacaacatcaagTCGCAGGGAATTAATCGAATGCAATATTTGTGGAAACGTTTTTACGCATTTAAATTCACTGAAAACTCATCTGCTCAAGCATTCGGGGGAGAAACCTTTCAAGTGTGAATTCTGTGATAAGGCCTTTGCCAGAAAAACAGTCCTCAATATACACCGGCGGTTGCACACCGGTGAGAAGCCATACAAGTGTTCGCTGTGCCCAAGCGCCTATGTTACTAAGGAAGCTCTTGCGCGCCATTTACAAAAGGACCACGTAGAAGAAGTGGGATCAAATTTCCGGCGAGATAAGGTATCATACATTTGTTCCATATGCAATAAGTCTCGTTGTTCCAAATACTCCCTCGCTTCTCATATGAAGAcacattttaatgaaacaaaagtGCGTCGAAAAATAGTTCGTAAAAGAAGGGAAAAACAGCCAGCTGGCCGAGATGGTGTCGCATCAACAGACCTAGCGACACAACATAACGTCGTCTTAAAATATTCTTGCAAAATCTGCCACAAGGGCTTCCCCAATAAATGGGAACTATGTACACATGCTGAATCGCACAACATGCACAAAACATTCGAATGTGACGTTTGCCAGAGAACGTTCGAAAAGAAGTTCCAATTGCTTTATCACTTACAAACCCACGATGGTGGTGAAGAATTGGTGAAAGCTAAAGTGAAACCAAGAAGTTGCGCCGAACAAACAATTCCTAGCGAAGAGAAAGAGGAGGTGAAGGTAGAAGAGGAGCCGTTGTCATCTGAGAGGAAAAGTAATAGAAAACTGCGCGTATCGAACCGtcgaaaaaagaaatcaaaaattgattataAGGAAGAGCAGGATGGGGATGAGGAAATAACTAGCGATAAAAGTGAAGAAAAATACTGCGACAATGATAAAGCGACAaagatttccaacaaaaaaagaaacaaccgAGCCCAACGGGAAAATCTTAAAGTTATGCGAACGAGTAGTAAAATAGAGTGTCTTATATGCCAAACTGTTTTTACCCATCCCACATCCCTCAAAACACACATGCTTGTCCATTCGGGTGAACGCCCATTCAAGTGTGATCACTGTGATAAGTCATTTGCCAGAAAAACCGTTCTTAATATCCATCGAAGATTGCACACCGGTGAGAAGCCCTACAAATGTCCCCTCTGTGATAGTGCTTGTGTCACAAAGGATGCTCTTATGCGTCACATGTCCAAGGATCACGATGACGATCGGGAAGCTGATCGTATAAAATTCACCTGTGGTATCTGCCATAAAGCAATGGGTACCAAGTACTCTCTGCAGACGCACATGAAACTTCACGAACAGAGCACAACAACAAGTACAGCTGAGCTGAATTTCTCTTGTAACATGTGCACCGAGTCCTTCGATACGAAGGATGATTATGCAAAGCATATGGAGGTACATGACTCGCATAGGAATTTCCAGTGTGACATCTGCCAGGTGACATTCGAGAAGAAATTCAAACTTCTATTTCATTTGCAAACACACAAAATTGAGGATTTGCCATGCAAGAAATGTGGCGAGACTTTTACTATAAGAGAAAATCTCATACAACACGTCAAGATGCAACACATCGACCCTCAAAATATGGACTTTCAATGTCCCACCTGCAACCTGGGGCAATATGATACTCGGGATCTAAAGTTACACGTGCTGAATGTACACGAAGTGGTCATGGGTGAATTGAATTCTTGCGATATGTGTGGTGAAAGCCATTCTACTGCAGCCGAGTACTACAAACATATGCACGATAAACACGATTCAATTAGCAAAACGTGCAATGAGTGTAAGAAGTACTTTGACTCGCGGAAAGCATTCGATAAGCACATACTTACGCATTACATGTGA
Protein Sequence: MSVKLDDSVCRVCLSSSGSITIFDDCGKDDQFRYCTSLEASKNDGLPSKLCKKCNDHLKVAYDFRFQAIYAEKYFRKTIFLPSFKKEDDGATSNGDEVDRNTNNHCSDELDENMAEIDMLLAIHTESVDDVNGHNKDDDNNDGIMDNTEFFDNDSVDIDEKHVEIIGMETFEREKREQKEQKVKLEIANVPPPLVSITERKTRFEMSSGAISSIPLKSPELPASNIVQQTQVSLDEIQQYPDSGSFAHHTQSVQEITVENTNGRSEHLEIHPVLKNDPSGYDFTVPSTVAVGFDSYSTPSQIQFQQMPLQIEYEQQHNSLPLQDSVHPNSENYDFPYQEPFSTYGTQNNEIVPQQQQENIQQYQQQNQVPDELPNNNTFKTEYLEGIVVAKAKKTKTTSSRRELIECNICGNVFTHLNSLKTHLLKHSGEKPFKCEFCDKAFARKTVLNIHRRLHTGEKPYKCSLCPSAYVTKEALARHLQKDHVEEVGSNFRRDKVSYICSICNKSRCSKYSLASHMKTHFNETKVRRKIVRKRREKQPAGRDGVASTDLATQHNVVLKYSCKICHKGFPNKWELCTHAESHNMHKTFECDVCQRTFEKKFQLLYHLQTHDGGEELVKAKVKPRSCAEQTIPSEEKEEVKVEEEPLSSERKSNRKLRVSNRRKKKSKIDYKEEQDGDEEITSDKSEEKYCDNDKATKISNKKRNNRAQRENLKVMRTSSKIECLICQTVFTHPTSLKTHMLVHSGERPFKCDHCDKSFARKTVLNIHRRLHTGEKPYKCPLCDSACVTKDALMRHMSKDHDDDREADRIKFTCGICHKAMGTKYSLQTHMKLHEQSTTTSTAELNFSCNMCTESFDTKDDYAKHMEVHDSHRNFQCDICQVTFEKKFKLLFHLQTHKIEDLPCKKCGETFTIRENLIQHVKMQHIDPQNMDFQCPTCNLGQYDTRDLKLHVLNVHEVVMGELNSCDMCGESHSTAAEYYKHMHDKHDSISKTCNECKKYFDSRKAFDKHILTHYM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00894178;
90% Identity: -
80% Identity: -