Basic Information

Insect: Melangyna quadrimaculata
Gene Symbol: -
Assembly: GCA_949320155.1
Location: OX439483.1:173381819-173386449[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.0017 0.43 13.2 3.3 1 23 17 39 17 39 0.98

2 27 3.5e-06 0.00091 21.6 1.3 1 23 46 68 46 68 0.97

3 27 3.5e-05 0.0092 18.5 1.1 1 23 187 210 187 210 0.95

4 27 6.4 1.7e+03 1.9 7.6 1 23 217 239 217 239 0.97

5 27 0.029 7.6 9.3 0.0 3 22 280 299 278 299 0.92

6 27 7.6e-06 0.002 20.6 1.2 2 23 312 333 311 333 0.97

7 27 0.00021 0.055 16.0 1.8 1 23 340 362 340 362 0.96

8 27 0.023 6.1 9.6 1.7 2 23 376 397 375 397 0.94

9 27 0.021 5.4 9.7 0.7 1 23 475 498 475 498 0.96

10 27 0.36 95 5.8 0.4 1 21 507 527 507 528 0.93

11 27 0.87 2.3e+02 4.6 0.2 3 20 539 556 538 558 0.93

12 27 0.0044 1.1 11.9 2.7 2 23 569 590 568 590 0.98

13 27 2e-05 0.0052 19.2 0.7 1 23 597 619 597 619 0.98

14 27 0.0036 0.95 12.1 2.7 1 23 765 788 765 788 0.98

15 27 0.0087 2.3 10.9 1.2 1 23 825 848 825 848 0.96

16 27 0.03 7.9 9.2 3.6 1 23 858 880 858 880 0.96

17 27 3.8e-06 0.00099 21.5 1.0 1 23 887 909 887 909 0.98

18 27 0.012 3.1 10.5 0.2 2 23 933 955 933 955 0.96

19 27 0.0016 0.4 13.3 1.3 1 23 996 1019 996 1019 0.97

20 27 0.1 27 7.5 0.7 1 23 1056 1079 1056 1079 0.91

21 27 0.0012 0.3 13.7 2.6 1 20 1085 1104 1085 1105 0.95

22 27 0.00011 0.03 16.9 1.8 1 23 1115 1137 1115 1137 0.98

23 27 1.8e-05 0.0047 19.4 0.3 2 23 1159 1180 1158 1180 0.95

24 27 0.00027 0.071 15.7 3.3 1 23 1186 1208 1186 1208 0.99

25 27 7.9e-07 0.0002 23.7 3.4 1 23 1214 1236 1214 1236 0.98

26 27 6.7e-07 0.00017 23.9 2.4 1 23 1242 1264 1242 1264 0.99

27 27 0.00028 0.073 15.6 0.2 1 23 1270 1294 1270 1294 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.0017	0.43	13.2	3.3	1	23	17	39	17	39	0.98
2	27	3.5e-06	0.00091	21.6	1.3	1	23	46	68	46	68	0.97
3	27	3.5e-05	0.0092	18.5	1.1	1	23	187	210	187	210	0.95
4	27	6.4	1.7e+03	1.9	7.6	1	23	217	239	217	239	0.97
5	27	0.029	7.6	9.3	0.0	3	22	280	299	278	299	0.92
6	27	7.6e-06	0.002	20.6	1.2	2	23	312	333	311	333	0.97
7	27	0.00021	0.055	16.0	1.8	1	23	340	362	340	362	0.96
8	27	0.023	6.1	9.6	1.7	2	23	376	397	375	397	0.94
9	27	0.021	5.4	9.7	0.7	1	23	475	498	475	498	0.96
10	27	0.36	95	5.8	0.4	1	21	507	527	507	528	0.93
11	27	0.87	2.3e+02	4.6	0.2	3	20	539	556	538	558	0.93
12	27	0.0044	1.1	11.9	2.7	2	23	569	590	568	590	0.98
13	27	2e-05	0.0052	19.2	0.7	1	23	597	619	597	619	0.98
14	27	0.0036	0.95	12.1	2.7	1	23	765	788	765	788	0.98
15	27	0.0087	2.3	10.9	1.2	1	23	825	848	825	848	0.96
16	27	0.03	7.9	9.2	3.6	1	23	858	880	858	880	0.96
17	27	3.8e-06	0.00099	21.5	1.0	1	23	887	909	887	909	0.98
18	27	0.012	3.1	10.5	0.2	2	23	933	955	933	955	0.96
19	27	0.0016	0.4	13.3	1.3	1	23	996	1019	996	1019	0.97
20	27	0.1	27	7.5	0.7	1	23	1056	1079	1056	1079	0.91
21	27	0.0012	0.3	13.7	2.6	1	20	1085	1104	1085	1105	0.95
22	27	0.00011	0.03	16.9	1.8	1	23	1115	1137	1115	1137	0.98
23	27	1.8e-05	0.0047	19.4	0.3	2	23	1159	1180	1158	1180	0.95
24	27	0.00027	0.071	15.7	3.3	1	23	1186	1208	1186	1208	0.99
25	27	7.9e-07	0.0002	23.7	3.4	1	23	1214	1236	1214	1236	0.98
26	27	6.7e-07	0.00017	23.9	2.4	1	23	1242	1264	1242	1264	0.99
27	27	0.00028	0.073	15.6	0.2	1	23	1270	1294	1270	1294	0.93

Sequence Information

Coding Sequence: ATGAGTACAcgtagcaaaacaaaaaaaacaaaatcaaagtcTGGTCGTTTCGAGTGTGACCATTGTAGTAAAACGTTTGCATGGAAAAAAGATCTATTTCGTCATGAAAAATCTCATGAACCTAACACAAAGAAGTTTGCATGTCCACATTGTGATCGTCGATTTATACGAAAGGATAAGCTTCAATCACATGTGATGGTCCATTTGGGTGGTATTGTAAAACCTCGATGTTCAAAAGCCACTCTAGCATTCTCACGTCAATTGTATTCTcaagaaaaattcaaagaaatagTCTGCATGATTTGTAATTACGACAAATCGGTTAATATAAAAGACCTCTATAAGCATATCAGCTTACACGACATGCAACAGCTAGAATTATTCGAGAATAGTGAATGTGTGAAGAGATTTTACGCTGGCAAAAACTTGCAAGAGGTCATGATGCTAATTTCCAATCAAATTGAACAGAAAGAGTTTGGAAAACTGCATTCCATTGTCAATGCAAATGGCTTCGAAATGGGTATCAGCGATTCAGATGAGAGCGATCCAGAAACTGCATATACATGCGAAATTTGCAATGAGTCATTCAACCGGAAACACAAGCTTATAGCACATTCATTATCTGGGCATACTGTTGACGAGTGTTTATATAAATGCGATAAATGTAAACTAGAATTCACTTGCAAAGAAGTGTTTAATAGCCACCAGAAACATCATTGTAACAATGTCGACAAAGAGTTCCACTGTGAGAACTGTCCAGCCAGATTTGCTTGGCCCCAAAATCGGGCAAATCACAAATGTAACAAAGAAAACGAGTCTCAAAAGGACAAAACGGTTTGCGAACCTTGCGGAGAAGTTTTCGCCACTCTTAAAGCTTTACGTCTTCATAAAAGGACAAAATGTGGTACGGTAGAGCTTGACAAAGAGAGCACCACCTGCGAAATTTGCAATAAAGTCTTCAGTTTCCCAAGAGATCtgagaaaacataaaaaaattcatataccGGACGGTAAGTCTCACGATTGTTCTGTATGCGGCGAGAAATTCCTTCGTTCTGACAATCTTCGAAACCATTTGAAGTCGCACAACAGTAAGCTTGAGAGGCCACTAGTAGCGAAAAAATTAATGTGTATGCTCTGTGGCCATAAATTCACAACTATCGGAAGCTTAAGATACCATTTATTTAACCACTCCGATGGCCAATCTGaaattgactttgaaaattcaGGTTTCGTTTTGAACTTCTATCCTGGCGTAGGCAAAGAAGTTGTTTCAGAATACATAAAGAATTGTTTTAATGAGCAAAAACTTTCGCAACTGTATATAGCAGTTAATAAAATAGGACTTGAGATGACATTAAGTGATTCTGATAGTGATGACGATGAACAAACCTACAAAGATCACGAAACTCCCTCGAAAACTTACGTATGTGAGCTGTGTAATGTCAAGTTTCCTCGTCGACAAGCTATTCTTCAGCATCAACACTCTGAACATGATTTGAAAGAAGGTAATTTCCCTCATAAATGTGTCAAGTGTGAAGATCAATTTGTATCTGCGGCCCTTTTGGAGCGTCATTTCAAAAGTGAATGTCAAAATGATGCCAGAACTAATGCTTGCGTCAAATGTGGTATAAAATTCATTTGGAAAGAAAATTTGGTTGCTCATACTTGCTTCAAAGAGGAGAAAAGCCCAGAAGAGAATAAACAATGTGAAGTGTGTGGTAAGAAGTTTATTTGGCTAAAGGATTTGCATCGACATAAACGAAGTCACATACCTTATGAAAAGAAATTCGAGTGTCTTGTGTGTGCTAGAAAATTCAACCGCAAGGATAACATGAGAGCTCATATGAAAGTTCACACCACTGAACATCAAGTTAGAGAGGCAAAGATATCGATAAAGTGGGAACAACAAGATGAGAATCTATGCAAGCCCAATGGTCAGAAAGTTATACagtgtaaaatttgtttgtcaaagCATAACACAATAAAAGATTTAACAACTCATTTGATGAGCCACAAAGACCCTGCAACCTTCAAGCAAAGAGAGACAGAGGCCAGAGAGATTTCGATGATGATATATGGAAAGCAAATGGAGATGCAGACTCTGGAAAGAGCAATTTGCAAAGATCTTGATAAAGGCAGCAATACGCGTTTCTATTCAATCACCAACGAAGCCGGTTATGAGTTGAATTTAAATGATTCAGAAACATGTTCAGACTTTGATGCggatgatgacgacgacgattcCGATGATGATGAAATTTTAAGAGATCGGAAACGTGTTCTCAAAGGATACAACTGCCAAATATGTAGTCAGAACTTTAatagaaaattcaaaatattcgaACATCAAAGAACGGAACATCCATGGGAGGAACTGCCATACGAGTGCCACCGATGTGGTTCAAAGTTTGTGTGCGAGAGAATTTATCATTTACATTCGCAGAATGATTGCGACAATAATGAGAAACAATTCAAATGTAAAACTTGTCCGGTGAAATTCGCTTGGAAAGAGAATCTTAAGAATCATGAGAAGTATATGCATGATCAAAATCCAGCAATGCCAAAGAAACATCATTGCGATATTTGCGGAAAGAGTTTCCTTTGGGTTAAAGATTTAACACGCCATCAGAAGACACATCAAACGGAAGATGAGAAATTCGAATGCACTTGGTGCTTTAGAGTCTTCATGCGCAGAGATAATCTTAAGGTTCATATGAAAGTGCACCAGAACGCTACACACATTTTGTTGCCAGACATCTATTACCTTGCTCGACCCAATGGAGCAAAAGTTGCTCAATGCAAACTTTGTGATCAGCAATATACAAACATATTTGATTTAGCAGATCACATTCAAAATGGACATATTAAATTACAGATGCTCAGCATCACTCCCAACCCAGCCAGCTATTCAATAACAAACGCTTTAGGCTATGAGATGGATATAAATGATTCCGAGACAGAGCGCGAGGGTGATGATAACAAGTACTTTTGTGAGATTTGTGATGCTCGATATAACCGTCGCTTCAAATTGCTGCAACATCAGCAATCGTTACATTACTCTGATAACATTCCTCACAAGTGTATCGATTGCAGTTTCAAGTGTGTCTCAGAGATAGTTCTCAATTATCACATGCGGACTCAGTGCATGAATCTAGTTAAACAGTTCCGCTGCAGCAAGTGCACTATGCGTTTCATGTGGAAGGAGAATCTTGAAAATCATGAAAGCTTAATACACGATGGTAAGCGAAAACACACTTGTACCACTTGTAAAAAAGATTTCGCGACACAGCATGACTTGAGAAATCACACCGAATGCAAAGCCCCGGCTGAggaaaagcttttcaaatgtGAGTTGTGCGATCGTAAATACAATCGAAAAGATCGACTTATGAAACATGCGAAGGTTCACACTGCCGGCGGTAAAGAAACAAAAGCAAAACGTATTAAAACAGAAGCATCGGACAAGAAGTTCTTATGTGCATTTTGTGGCAAGGAAGTGTCGAGTTCATCTAATCTCGTCATACACATGCGACGACACACGGGTGAGAAACCTTTCAAGTGTGAATTCTGTAATAAGGGCTTTCCTAGATCTTCAGATTTGGCGTGTCATAGACGAACGCATACTGGAGAACGACCACATAAGTGCACAGTGTGTGAAAAAGCATTCTCCCGCTCGTACAAACTTCAGACTCATATGCGAATTCATTCTGGTGAGAGGCCTTACAAGTGCACTTACTGTGAGAAAAGCTTTACACAATCCAATGATTTGACACTTCATGTTCGTCGACATACAGGTGAAAGACCCTATGTGTGTGAAACATGTGGGGAAAGATTTATACAAGGAACTGCACTTAAAAACCATCGAAGAATGCGTGGGCATTACGAAATTTAA
Protein Sequence: MSTRSKTKKTKSKSGRFECDHCSKTFAWKKDLFRHEKSHEPNTKKFACPHCDRRFIRKDKLQSHVMVHLGGIVKPRCSKATLAFSRQLYSQEKFKEIVCMICNYDKSVNIKDLYKHISLHDMQQLELFENSECVKRFYAGKNLQEVMMLISNQIEQKEFGKLHSIVNANGFEMGISDSDESDPETAYTCEICNESFNRKHKLIAHSLSGHTVDECLYKCDKCKLEFTCKEVFNSHQKHHCNNVDKEFHCENCPARFAWPQNRANHKCNKENESQKDKTVCEPCGEVFATLKALRLHKRTKCGTVELDKESTTCEICNKVFSFPRDLRKHKKIHIPDGKSHDCSVCGEKFLRSDNLRNHLKSHNSKLERPLVAKKLMCMLCGHKFTTIGSLRYHLFNHSDGQSEIDFENSGFVLNFYPGVGKEVVSEYIKNCFNEQKLSQLYIAVNKIGLEMTLSDSDSDDDEQTYKDHETPSKTYVCELCNVKFPRRQAILQHQHSEHDLKEGNFPHKCVKCEDQFVSAALLERHFKSECQNDARTNACVKCGIKFIWKENLVAHTCFKEEKSPEENKQCEVCGKKFIWLKDLHRHKRSHIPYEKKFECLVCARKFNRKDNMRAHMKVHTTEHQVREAKISIKWEQQDENLCKPNGQKVIQCKICLSKHNTIKDLTTHLMSHKDPATFKQRETEAREISMMIYGKQMEMQTLERAICKDLDKGSNTRFYSITNEAGYELNLNDSETCSDFDADDDDDDSDDDEILRDRKRVLKGYNCQICSQNFNRKFKIFEHQRTEHPWEELPYECHRCGSKFVCERIYHLHSQNDCDNNEKQFKCKTCPVKFAWKENLKNHEKYMHDQNPAMPKKHHCDICGKSFLWVKDLTRHQKTHQTEDEKFECTWCFRVFMRRDNLKVHMKVHQNATHILLPDIYYLARPNGAKVAQCKLCDQQYTNIFDLADHIQNGHIKLQMLSITPNPASYSITNALGYEMDINDSETEREGDDNKYFCEICDARYNRRFKLLQHQQSLHYSDNIPHKCIDCSFKCVSEIVLNYHMRTQCMNLVKQFRCSKCTMRFMWKENLENHESLIHDGKRKHTCTTCKKDFATQHDLRNHTECKAPAEEKLFKCELCDRKYNRKDRLMKHAKVHTAGGKETKAKRIKTEASDKKFLCAFCGKEVSSSSNLVIHMRRHTGEKPFKCEFCNKGFPRSSDLACHRRTHTGERPHKCTVCEKAFSRSYKLQTHMRIHSGERPYKCTYCEKSFTQSNDLTLHVRRHTGERPYVCETCGERFIQGTALKNHRRMRGHYEI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00984436;
90% Identity: iTF_00664263;
80% Identity: -