Mper020278.1
Basic Information
- Insect
- Melanchra persicariae
- Gene Symbol
- -
- Assembly
- GCA_947386135.1
- Location
- OX376644.1:3769506-3772667[-]
Transcription Factor Domain
- TF Family
- DACH
- Domain
- DACH domain
- PFAM
- AnimalTFDB
- TF Group
- Unclassified Structure
- Description
- This family of proteins includes transcription factors involved in the regulation of organogenesis. Members of this family appear to regulate the SIX1, SIX6, and possibly SIX5 genes, influencing myogenesis and the proliferation of precursor cells in myoblasts. They are known to act as corepressors or coactivators in these processes, depending on their interaction with other proteins such as EYA3, CREBBP, NCOR1, TBL1, HDAC1, and HDAC3. These proteins are also implicated in the repression of cyclin-dependent kinase inhibitors, including the p27Kip1 promoter, which is key in cell cycle regulation. Some family members inhibit TGF-beta signaling through interactions with SMAD4. They are characterized by a conserved DNA-binding domain known as the DACHbox-N or DD1 domain, which is structurally similar to the forkhead/winged helix domain and is responsible for their DNA-binding activity.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0025 21 5.1 0.2 75 135 50 110 43 125 0.76 2 12 0.0031 25 4.8 0.1 80 149 111 178 102 207 0.53 3 12 0.0047 39 4.2 0.1 75 147 218 291 212 303 0.81 4 12 0.001 8.4 6.3 0.7 75 156 316 395 309 403 0.74 5 12 0.0073 60 3.6 0.1 75 138 400 463 393 493 0.66 6 12 0.02 1.6e+02 2.2 0.1 75 147 442 515 438 529 0.77 7 12 0.0027 22 5.0 0.3 75 137 526 588 516 610 0.73 8 12 0.0038 31 4.5 0.1 82 149 575 640 566 667 0.51 9 12 0.0064 53 3.8 0.1 75 150 666 739 649 763 0.67 10 12 0.0088 72 3.3 0.1 75 146 750 822 739 835 0.77 11 12 0.0045 37 4.2 0.1 76 137 835 896 829 919 0.69 12 12 0.0032 26 4.7 0.2 76 136 933 993 902 1017 0.57
Sequence Information
- Coding Sequence
- ATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTTGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAATCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATAGATGCATCCGAGGCTCGGAAGAGTCTCAATGTGTTCCTAATAGATGAATCCGATGCTCGAAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAAGAGTCTCAATGTGTTCCTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGAGGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATGCTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTACTAATAGATGAATCCGATACTCGGAGGAGTCTCAATGTGTTCCTAATGGATGAAtccgatgctcggaggagtctcaatgtgttcctaatggataaatccgatgcatccattcatggaccgacctcggttagcgttgcttaa
- Protein Sequence
- MDESDARRSLNVFLMDESDARRSLNVFLIDESEARRSLNVFLIDASEARRSLNVFLMDESEARRSLNVFLIDESEARRSLNVFLMDESEARRNLNVFLMDESDARKSLNVFLMDESDARKSLNVFLMDESDARKSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLIDESDARRSLNVFLIDESDARRSLNVFLIDESDARRSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLIDESDARRSLNVFLMDESEARRNLNVFLMDESDARRSLNVFLIDASEARRSLNVFLIDASETRRSLNVFLMDESDARRSLNVFLMDESEARRNLNVFLMDESDARRSLNVFLMDESEARRSLNVFLMDESEARRNLNVFLIDESDARRSLNVFLMDESEARRSLNVFLMDESDTRRSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLMDESDARKSLNVFLIDESDTRRSLNVFLIDESDTRRSLNVFLIDESDTRRSLNVFLIDASEARRSLNVFLMDESEARRSLNVFLMDESEARRNLNVFLMDESDARKSLNVFLMDESDARKSLNVFLMDESDARKSLNVFLMDESDARKSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLIDESDARRSLNVFLIDESDARRSLNVFLIDESDARRSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLIDESDARRSLNVFLMDESEARRNLNVFLMDESDAWRSLNVFLIDASEARRSLNVFLIDASETRRSLNVFLMDESDARRSLNVFLMDESEARRNLNVFLMDESDARRSLNVFLIDASEARKSLNVFLIDESDARRSLNVFLMDESEARRSLNVFLMDESDTRRSLNVFLMDESDARRSLNVFLMDESDARRSLNVFLMDESDARKSLNVFLIDESDTRRSLNVFLIDESDTRRSLNVFLMDESDTRRSLNVFLMDESEARRSLNVFLMDESDARRSLNVFLMDESDTRRSLNVFLMDESDTRRSLNVLLIDESDTRRSLNVFLMDESDARRSLNVFLMDKSDASIHGPTSVSVA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -