Basic Information

Insect: Melanaphis sacchari
Gene Symbol: -
Assembly: GCA_002803265.2
Location: NW:8812299-8821870[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.4e-06 0.00024 20.8 3.6 1 23 209 231 209 231 0.98

2 14 0.00034 0.025 14.5 3.7 1 23 237 259 237 259 0.97

3 14 0.00089 0.065 13.1 1.8 1 23 348 370 348 371 0.94

4 14 3.8e-05 0.0028 17.4 1.1 1 23 405 427 405 427 0.98

5 14 0.23 17 5.6 1.9 2 23 445 466 444 466 0.91

6 14 0.024 1.7 8.6 0.1 2 23 477 499 476 499 0.91

7 14 0.00026 0.019 14.9 1.8 1 23 506 528 506 528 0.98

8 14 0.0012 0.085 12.8 3.1 5 23 537 555 534 555 0.94

9 14 0.0056 0.41 10.6 0.0 3 23 562 582 560 582 0.95

10 14 1.7e-05 0.0013 18.5 0.2 1 23 598 620 598 620 0.98

11 14 0.00012 0.0085 15.9 0.2 3 23 628 648 626 648 0.97

12 14 1.1e-05 0.0008 19.2 0.1 1 23 654 676 654 677 0.95

13 14 0.00036 0.026 14.4 1.6 1 23 690 712 690 712 0.96

14 14 2.8e-06 0.0002 21.0 0.1 2 23 990 1012 989 1012 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.4e-06	0.00024	20.8	3.6	1	23	209	231	209	231	0.98
2	14	0.00034	0.025	14.5	3.7	1	23	237	259	237	259	0.97
3	14	0.00089	0.065	13.1	1.8	1	23	348	370	348	371	0.94
4	14	3.8e-05	0.0028	17.4	1.1	1	23	405	427	405	427	0.98
5	14	0.23	17	5.6	1.9	2	23	445	466	444	466	0.91
6	14	0.024	1.7	8.6	0.1	2	23	477	499	476	499	0.91
7	14	0.00026	0.019	14.9	1.8	1	23	506	528	506	528	0.98
8	14	0.0012	0.085	12.8	3.1	5	23	537	555	534	555	0.94
9	14	0.0056	0.41	10.6	0.0	3	23	562	582	560	582	0.95
10	14	1.7e-05	0.0013	18.5	0.2	1	23	598	620	598	620	0.98
11	14	0.00012	0.0085	15.9	0.2	3	23	628	648	626	648	0.97
12	14	1.1e-05	0.0008	19.2	0.1	1	23	654	676	654	677	0.95
13	14	0.00036	0.026	14.4	1.6	1	23	690	712	690	712	0.96
14	14	2.8e-06	0.0002	21.0	0.1	2	23	990	1012	989	1012	0.96

Sequence Information

Coding Sequence: ATGGACACTAACTTTGTGGAAGAAATCGTGTCCATCAATCCTGGTAGCCAAACGCTAGATTTTGATAGAAAGGACTCTGTTTTATGTCCAGACAGTGTTAACTCTATTGTCAAGACCGAGTTTTTCAGTCCGGATGATATTGATGATGCTATGTCGTcagataattgtttaatacaaaCCATTGAGTCCTCATATTTCACCAACAGTAGTACACGCGAAAATGAGCTCAATAATATGACTAGAGCGGTCATGGAATCTGTGCCATATGCCGATGGGTTACAATACTTAGCTGCCATATCTTCATTCAGTGATAATTTTAAGgaAATGGATCCTGGGCAGCAAATCAAACAAGAGCCTGTTGATCCTGGTGATTTATTTGAGTCTAGTGATGAAGAAGTTGTCCAACAAATGACCCAAGAGGAATACCAAGATTTTTTTGATGTTCAAGAAGAAGTTGTTGTTCAAGAATGCCCCGAGCAAGAGATAATGACTCAAAGTTGGGAAATGAACCGCTCTACTAATATTGACACcatattaGAAACAGAAGTTGAATGTATGTCATCAAATGTTGATGTTGACATACCAATACCTGAAGGCGAAGAAGCTTCATCTTCCGTTAATCCATATCCATGTGATTTTTGTAGTCGGAGATTTAATCGAAAATCACATCTTATGAACCATATGGTTACCCATCAATCTGAGCGTCCCTTTTGTTGTGCATTATGTGGTGTCCGTTATCGACGTAAATGTGATTTAGCCAATCACATGAAAATTCATATTGGTCCTAATAATCAATCAGATAGTggtttagataaCCAAAATGTATCTGTTACAAAAGTAATGAACAAATTAATGTTTGTGGATCCAATACATAGAAGGAGTGTTACACCTGGTGAAGATTCTGAAGATAAAGGAGACATAAATCAAGAaccaaatacaaaaaatcGTGGTCGTGGTAAAGGTCGGGGTAGAGGAAAAGGCCGTCCCATGAAAGATCGTTTAATTACTCTTGGTTGGAATTCAGAAATTTACTCAAAACCACATACATGTAACCCATGTGGAATTTCATTTACACGTGAAAAAGCTCTTCTTAATCATGCTCGTCTTCATCATAGTGATGatgatgtaaatattgtaaccactcaaaaatcaaattcagATAGTTATGAGCTTACAATATTGGCTAATTCTAAATCCAGCGATGTAACTTCTTACTCTTGTGATTCATGTGGAGCAGTATTTGAcagatttgattttttaaaacgtcatcaaagGCAGCATATGAAAAAAGAACTTGGAAATGTTGAAGAAGAAATATATGAAGAAGCacatatgtgtatacattGTGGATTGTTCTTCAAGTCTATGCCAGAATTAGAAATGCATACTGAGCAACATTTGATCCCTACAAATATTTCTgaaaaatcaaaatgtttGGCTTGTGGTGAAACATTTGATAGTACAGATGAGTTGTCTGATCATGTATCTCAAATTCATACTGATTCATTACCTGAATATTCATGTAAACTTTGTGGAAAATTATGCAAAGACGATAAAGCTCtccaaaaacatttaatgattCATGACACATccgataataattgtataatgtgtGGTAAAAGATTTCATTCCAGAGCACGTCTGAAACGtcatATGATAACTCATCGAGAGAAAGGAGTTATTTGTGATATTTGTGGTGAAGAAGTAGCTGATAAACGAGcacttattaatcataaagCCAGTCATGCAAATACTGTTAGTATTTCACGAAATTCACtgactgaaaaaatatttccttgTTCTAGTTGTGGCAAAgtatttggATCTCGATCATCTCAACAAATACACATACGAATACATACCGGAGAACGACCTTATGGTTGTAAATATTGTAGCAAAGCTTTTGCTGATGGTGGTACTCTTCGAAAACATGAGCGTATACATACTGGTGAAAAGCCATATGCTTGTCCTGTCTGTCCAAAGGCATTCAATCAGagagtTGTATTACGTGAACATATAAGAGCACATCACGCTGGAACTGAGGCGAAGGGTAGTCAAgtgaatttttatgaatgtaaAGTGTGTGGATATTTGTTCCGATCTTCAATGGAGCTTTGTTCACATTTAGTTCAGCATAGCGATGAAAATACTAAAAGATCTAGAATAGTacctgTTGGACCTCGCAAGTATAAGCGTCGCAGCAAGTTGGGTAATCGAAAAGACACATGGTGTTTAGTAGAAAAAGTATTCACAGTTATGTCAGGGCAGTCAGATACGGAAAGCTGTGAAGATGAACCCATACCTACAGTAGAAGAGCAAGCTGTTCAATCAATTATAGAAAAGGAAGATATATCTTACAATCCTCCAACTATACCTAGTCCTCCTAGTAAGTCTCCAGTTAAGACATACAAAATTGTTAATGGAAGGTTAGTGAAGAGTGAACAAAAGTCTTCTAAACAAGGTCCATGTGAATCAAAACAAACTGTTACCAAGTCAGAATTAGTACCAAAAAAACATAGCTTTGTGCTTAAAGATGGAGAGTGCACTAGAACATGTTCAACTGTACTTTATTATTCTTCAAGATCTGATCCTACAGTTATGGAATCATCATTAGGAGAAGAATCCAAAGAAAATGATAATCCAGAAGAACCTGAAGACCAAATTTCTGTAGAAGATACCGATTTTACTAACATGAAGATGGAGGCAGTTAGTGCTCagtcaatatttaatgtacaagATTTAGACAACATATGCAACATTGATTTTCCTGATGAAGGTGgagtacaatattttgtagagAATAATGATGGTCGATATGGCAATCATTGTGATTTAATTCTGGAATCTTCAAATGATGATTGCATGATTGAAACAGAACTAGTGTTTGATACAGATTATGTTGAGGAGGTTGGTGCTAACATTGAATTGAGTACTGAAGAAATGGCTCCTGTGTTTGCAGAAATTATTTCTTGTGATATTTGCGATGAAGTATTTGAGGATAGAAAAGAACTCATGAGACACATTCAAACCATGCATATTGGATAA
Protein Sequence: MDTNFVEEIVSINPGSQTLDFDRKDSVLCPDSVNSIVKTEFFSPDDIDDAMSSDNCLIQTIESSYFTNSSTRENELNNMTRAVMESVPYADGLQYLAAISSFSDNFKEMDPGQQIKQEPVDPGDLFESSDEEVVQQMTQEEYQDFFDVQEEVVVQECPEQEIMTQSWEMNRSTNIDTILETEVECMSSNVDVDIPIPEGEEASSSVNPYPCDFCSRRFNRKSHLMNHMVTHQSERPFCCALCGVRYRRKCDLANHMKIHIGPNNQSDSGLDNQNVSVTKVMNKLMFVDPIHRRSVTPGEDSEDKGDINQEPNTKNRGRGKGRGRGKGRPMKDRLITLGWNSEIYSKPHTCNPCGISFTREKALLNHARLHHSDDDVNIVTTQKSNSDSYELTILANSKSSDVTSYSCDSCGAVFDRFDFLKRHQRQHMKKELGNVEEEIYEEAHMCIHCGLFFKSMPELEMHTEQHLIPTNISEKSKCLACGETFDSTDELSDHVSQIHTDSLPEYSCKLCGKLCKDDKALQKHLMIHDTSDNNCIMCGKRFHSRARLKRHMITHREKGVICDICGEEVADKRALINHKASHANTVSISRNSLTEKIFPCSSCGKVFGSRSSQQIHIRIHTGERPYGCKYCSKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHAGTEAKGSQVNFYECKVCGYLFRSSMELCSHLVQHSDENTKRSRIVPVGPRKYKRRSKLGNRKDTWCLVEKVFTVMSGQSDTESCEDEPIPTVEEQAVQSIIEKEDISYNPPTIPSPPSKSPVKTYKIVNGRLVKSEQKSSKQGPCESKQTVTKSELVPKKHSFVLKDGECTRTCSTVLYYSSRSDPTVMESSLGEESKENDNPEEPEDQISVEDTDFTNMKMEAVSAQSIFNVQDLDNICNIDFPDEGGVQYFVENNDGRYGNHCDLILESSNDDCMIETELVFDTDYVEEVGANIELSTEEMAPVFAEIISCDICDEVFEDRKELMRHIQTMHIG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01167906;
90% Identity: iTF_00135598;
80% Identity: -