Basic Information

Insect: Meiosimyza platycephala
Gene Symbol: Hr39
Assembly: GCA_963662105.1
Location: OY759210.1:91996976-92001004[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 1 1.1e+04 -3.7 0.8 115 192 62 84 13 107 0.47

2 5 3 3.2e+04 -15.0 22.8 69 160 248 362 214 422 0.44

3 5 3 3.2e+04 -5.9 9.4 59 163 349 464 316 485 0.43

4 5 1.9e-14 2.1e-10 41.4 0.4 1 149 577 730 577 745 0.61

5 5 4.1e-81 4.4e-77 261.1 0.3 200 408 746 947 735 947 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	1	1.1e+04	-3.7	0.8	115	192	62	84	13	107	0.47
2	5	3	3.2e+04	-15.0	22.8	69	160	248	362	214	422	0.44
3	5	3	3.2e+04	-5.9	9.4	59	163	349	464	316	485	0.43
4	5	1.9e-14	2.1e-10	41.4	0.4	1	149	577	730	577	745	0.61
5	5	4.1e-81	4.4e-77	261.1	0.3	200	408	746	947	735	947	0.96

Sequence Information

Coding Sequence: atgtcaacaattAAGGCTGAAAATGCACCAAATGGTGCAATAGTAACCActtcaacaacaacagtacCAAGTGCCACGCCTTTTAGCACGAATATTGGCGGCGGCAGCAGCAACGCCTTTCAATTGTCCGCCGTTGCCGCTCCTGCCGCCTCTGCAATAACAACATCGACAACGACGACACGCAACAACATTTCAGTGACGAATATCAAATGTGAGGCTGATGATTTACGCATGTGTACGACTACCAGCgccccaacaacaacaacagcagcaacaacaactccAATTAATGGCAACCTTGTACCGGTGATCGCTACCAACAGCAGCGGCGGCGGCAGTTATTTCAATGGTGCTACTGGTATTGGTATACGGATACCAGTGCCAAAAGCTGAAGATTCCGATTCAGAAGCAGAACtcacaaatatcgaaaatttgaaagtgaCAAGAAGAACAAGCGGTAGCAGTAGCATTAGTGCATGTACTACacaaaattatagtaaaaatggACCACGACCAATGTCGTGGGAGGGTGAACTGTCTGAACCAGAGACAACGGAAACAGATCTTATGGAAACGGAGAATTCGGTTAGCAATGACAAACAGTATATGCCGCACAATATGGGAATGATAGGAGGAGGAGGTGTGGCAGTCAGCAACACCGGTTTGACTGTCATAAAAAGTGAAGCAACGACCACAACGCCAGCGCCGCCTACAACTGCTCCACCGTCATTTCATTCGCAGCaacatcatcatcttcatcagcaCCACCACCAACGTCAACATCATGCGAATATCAAGCCTGAGATGGAACAAATTTCCGTAGAAATCTTAAGTGCACAGTCCACACTAATAACGccgtatcaaaaaattaaactcaccCATCAGCCACAGCAGCCGCTGCAAAGTGACCCCATCAATCTGAAGTATGAACCTGGCCTTGACAGTACGTCCACACCCACAACAGCGAATATCAATTCCCCGCTTCTTGCACGTAATAAATCCAGCAGTATGTTGCCAGCAAATCCTTCACCCGATTCCGCCATTCATTCCGTTTACACGCACAGTTCGCCCAGTCAATCGCCGCTGACATCACGCCACGCCCCCTATACGCCATCACTTAGTCGCAACAATAGCGATGCATCGCACAGCTCCTGTTATTCATACAGCAGCGAATTTAGTCCGACACATTCGCCCATACAAGGACGTCATTCCGCTGCGGCAGCTGCAGccgcagcagctgctgctgccgccTATAGCAGCTTCAATGGTGGCACACAACTACATCATTCCGTCTTGTATCGGCCAATCTCAATTGACAGCCCATCCAGTCCGGCGCTTATGAATGGCGATGCGTCAACAGCGCATAATTTGAGTAATAACGCACGCGCACGTGCTGCAAACGCCGGCCTTCCTCCTGAATGCGAAATGCTATTGGATGCtagcaataacagcaacattAATTCCTCCGATGCCTCTATACCTTCGCCGGGTATCTCACGTCAGCAGCTCATAAATTCGCCGTGCCCCATTTGTGGTGATAAAATTTCCGGTTTTCACTATGGCATTTTTTCTTGCGAGTCCTGCAAGGGCTTCTTCAAGCGAACCGTCCAGAATCGAAAAAATTATGTGTGTGTACGTGGTGGTCCCTGTCCGGTTAGCATATCAACGCGTAAGAAGTGTCCTGCATGtcgttttgaaaaatgtttgcagAAAGGCATGAAATTGGAAGCTATACGCGAAGATCGCACACGTGGCGGGCGTTCTACTTATCAATGCTCTTATACGTTACCGAATTCAATGTTGAGTCCGTTACTTAGTCCTGATCAACAAGGGGCTGCTGTTGCAGCAGCAGCGGCGGCAGCTATGGCAGCTGCCAATGCAGCGGCAGGAGGTGGCGGATCACAACTTCAACAGCAACGTACTGTATTGAGTGGTGGACCTGGTGGAAATGGTTATATCACTATTAAAACTGAACATGGTGAACATGCGGCCTTGAATGGAATTGGTGTTGGAATTACAGCTGCGCGCCCAAGCAGCAATATTCCTGTTTTATTGCAGGAAATCATGGATGTTGAACATCTTTGGCAATACAATGAAGCTGAATTGGCACGACTTAATCAACCGCTAACTTCTTCGTCCTCATCGTCATCCAGTTCATCAGCACATCATCATTCTTCTACAGGCAGCTCCAATCCAATCTCAACAAATCCACTGCTGGCCAGTGCTGGACTATCTTCAAATGGCGAAAATGCAAATCCGGATCTTATTGCACATCTTTGCAATGTGGCCGATCATCGTCTGTACAAGATTGTAAAGTGGTGCAAAAGCTTgccactttttaaaaatatttcgATTGACGATCAAATTTGCCTGCTTATTAATTCATGGTGTGAACTTTTGTTATTCTCCTGTTGCTATCGATCTATTGATACACCAGGAGAGATCAAAATGTCACAGGGCAAAAAAATATCCTTGGCGCAGGCTAAATCAAATGGTTTGCAGgcATGCATCGAACGTATGCTTAACCTGACAGATCACTTGATACGCTTAAGAGTCGATCGTTACGAATATGTTGCCATGAAAGTGATAGTGCTATTACAATCCGATACAACTGAGTTGCAAGAGCCTGTAAAGGTACGTGAATGCCAGGAAAAAGCTTTACAAAGTCTACAAGCATACACTTTGGCACACTATCCGGACACACCGTCAAAATTCGGCGAGTTATTGTTGCGCATACCTGATTTGCAGCGCACATGTCAACTTGGCAAAGAAATGCTGACAATTAAATCACGCGATGGTGGTGATTTCAATTTACTCATGGAACTGCTACGTGGAGAACATTGA
Protein Sequence: MSTIKAENAPNGAIVTTSTTTVPSATPFSTNIGGGSSNAFQLSAVAAPAASAITTSTTTTRNNISVTNIKCEADDLRMCTTTSAPTTTTAATTTPINGNLVPVIATNSSGGGSYFNGATGIGIRIPVPKAEDSDSEAELTNIENLKVTRRTSGSSSISACTTQNYSKNGPRPMSWEGELSEPETTETDLMETENSVSNDKQYMPHNMGMIGGGGVAVSNTGLTVIKSEATTTTPAPPTTAPPSFHSQQHHHLHQHHHQRQHHANIKPEMEQISVEILSAQSTLITPYQKIKLTHQPQQPLQSDPINLKYEPGLDSTSTPTTANINSPLLARNKSSSMLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQGRHSAAAAAAAAAAAAAYSSFNGGTQLHHSVLYRPISIDSPSSPALMNGDASTAHNLSNNARARAANAGLPPECEMLLDASNNSNINSSDASIPSPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCPVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQQGAAVAAAAAAAMAAANAAAGGGGSQLQQQRTVLSGGPGGNGYITIKTEHGEHAALNGIGVGITAARPSSNIPVLLQEIMDVEHLWQYNEAELARLNQPLTSSSSSSSSSSAHHHSSTGSSNPISTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCYRSIDTPGEIKMSQGKKISLAQAKSNGLQACIERMLNLTDHLIRLRVDRYEYVAMKVIVLLQSDTTELQEPVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKSRDGGDFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01486217;
90% Identity: iTF_01486217;
80% Identity: iTF_00972276;