Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000074.1:1327422-1336188[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.48 43 5.4 0.4 3 23 113 133 111 133 0.96

2 18 0.022 2 9.6 0.1 2 23 137 159 136 159 0.94

3 18 0.03 2.8 9.2 0.7 2 23 385 407 384 407 0.96

4 18 0.002 0.18 12.9 0.1 1 21 415 435 415 436 0.96

5 18 0.0044 0.4 11.8 0.4 2 23 446 467 445 467 0.93

6 18 0.52 48 5.3 0.7 1 23 483 506 483 506 0.91

7 18 0.005 0.46 11.6 2.2 1 23 515 538 515 538 0.95

8 18 4 3.7e+02 2.5 0.5 3 20 616 633 615 637 0.78

9 18 4.9 4.4e+02 2.2 1.6 1 23 642 665 642 665 0.91

10 18 9e-05 0.0082 17.1 1.2 1 23 671 693 671 693 0.96

11 18 1.9e-05 0.0017 19.3 1.7 1 23 700 722 700 722 0.98

12 18 7.8e-05 0.0071 17.3 2.3 1 23 727 749 727 749 0.96

13 18 0.00033 0.03 15.4 1.5 1 23 755 777 755 777 0.98

14 18 1.6e-06 0.00015 22.6 1.4 1 23 783 805 783 805 0.98

15 18 0.00029 0.027 15.5 1.7 2 23 812 833 812 833 0.98

16 18 0.00033 0.03 15.4 0.8 2 23 841 863 840 863 0.97

17 18 6.3e-05 0.0057 17.6 0.2 1 23 868 890 868 890 0.98

18 18 0.0055 0.5 11.5 0.8 1 23 896 919 896 919 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.48	43	5.4	0.4	3	23	113	133	111	133	0.96
2	18	0.022	2	9.6	0.1	2	23	137	159	136	159	0.94
3	18	0.03	2.8	9.2	0.7	2	23	385	407	384	407	0.96
4	18	0.002	0.18	12.9	0.1	1	21	415	435	415	436	0.96
5	18	0.0044	0.4	11.8	0.4	2	23	446	467	445	467	0.93
6	18	0.52	48	5.3	0.7	1	23	483	506	483	506	0.91
7	18	0.005	0.46	11.6	2.2	1	23	515	538	515	538	0.95
8	18	4	3.7e+02	2.5	0.5	3	20	616	633	615	637	0.78
9	18	4.9	4.4e+02	2.2	1.6	1	23	642	665	642	665	0.91
10	18	9e-05	0.0082	17.1	1.2	1	23	671	693	671	693	0.96
11	18	1.9e-05	0.0017	19.3	1.7	1	23	700	722	700	722	0.98
12	18	7.8e-05	0.0071	17.3	2.3	1	23	727	749	727	749	0.96
13	18	0.00033	0.03	15.4	1.5	1	23	755	777	755	777	0.98
14	18	1.6e-06	0.00015	22.6	1.4	1	23	783	805	783	805	0.98
15	18	0.00029	0.027	15.5	1.7	2	23	812	833	812	833	0.98
16	18	0.00033	0.03	15.4	0.8	2	23	841	863	840	863	0.97
17	18	6.3e-05	0.0057	17.6	0.2	1	23	868	890	868	890	0.98
18	18	0.0055	0.5	11.5	0.8	1	23	896	919	896	919	0.97

Sequence Information

Coding Sequence: ATGGCATCTGATGAATCGGACGACGAACCATTGTCAGTATTGGCAGCAGCAAAGAAGGTTGATCCCAAGAAGTTTGATTGCGAAATAATTCCGGTAGATGAGAAGTCTTCTAAAAAGCGTAATACTTCAACTAAGAAGACTAGTTTAACAATTAAAATAAACCGGCGACTCAAAACAATATCAGCGCCGCCTGTGATTGATAGGCCTACGGATGTGTGGCTATATTTAAAAGATTTAAATCCTACTGGACCGTACAAATGCCTTCTTTGCGCAGACTGGTTTATAAATCGCTCCAAAATGGTAGTACACTACGTTCTTAATCATAAGAAGGATTTTTGTGGTATCTGCAGGTATTTTGTTAATGATCGGGAAAGCTGGAAGTTGCATGTCAGATTCCATGAACCATGGCCTTGTTCTCAATGTGTGGAGACATTTCCCTCTGAATTATCTCTCAGACAACATCTTAGTTCTGTACACAAGCTTGTCCACTGCCGTCTATGCCACTTCAGGCTGCCAGTTGGTGAACAATATGATGCGCATTTAGCTCAAAAACATAATATCTCAAATGTCAATTGTAAAGATGAAGAATGCTTTTGGGAGATTGAAGATGAGGATTTGCTGAAGTTCAACTGCTGTTTATGCAGTAAGCAACATAATTTGTCATCAACATTCTTCACACACTATATGGGTTTTCACCACTTCACTCTGAAATGTATTACAGCCTTTATTTCTGGTTCAGATCCACCATTTACAGTTCATGGTGCAGAAATTAGTACACAATTTGTTGATGGGCAATTAAAGGATCTGAATGCATTCGGCTATGTTGATTTAGAGCAGAAGCCAAGAGAAGGTGTCCAAGATAAAGTTCACACGAATACTACTAGTTTATCAAAATCTATGACCGAAATAAAGAATGAGACAACTGAAGGTGATGAATCCAAAGCTGATGACTCATGTTCGAATAAAGTTATGCATCAGGTTGATGTAGAAGCATATGAGGGAGATGATGATTTTGACGTTACTCTAACTGAGTTGATTATACTTCAGAAATGTTACTTTGACTACATAAAAAAGATATTACATGATATCTCTCAGAACTTAGTACCTGTAATCTCTGATATTAATAACAGAAATGATGTTGTACTTAATGTAAAATGCCCTTTATGTGACAGTAAGTTCAATACTGGACAATTATTCATGAGTCATATGTACAAGATGCATAACGTTAAGTCCATTCCCAGTTATTCATGTAGGGTGTGTGGCACAAATTTTGACAGCTATAACGAGCTGGAGAGTCATATTATGGATGAGATAAATAATTTCGAAAACTTGTGGATATGTCAGTTTTGTGATAAAGAATTTGGTAACAGGGAGACTGTAAGGAGACATTTAACTGATCATTGGGAGGCTATAGAGTATGACAACTGTTTCAGCCCTCACTTGGGATTCAGATGCAAGTATTGTCCAACTCTATTTTGGAATGAGACCGACAGGGAAAGGCACCAAGTCAGAGTTCACTTTAATAAGTATACAGATCAATTTTATAAATGCAACAGTTGCTCTCTAACCTTCAGTGATAAGGTATGGTACATACACCACTATTTGGAAAACCACTTGAAAGGAGAGAAAATGGGCTCTTATCTTTTGAAATGCTGTGTCTGCTGTGTAGTTCTCTCTAGCATAGATGAGATGAGAACCCACTTCATAGATCAGCACCCTGAAGCGAGGAAAGTGTACTGTTCTCTAGACCCCTGCAAATACAAACCTCTCAGTCAGCGGAAGTCCTTGAAATTACATGTGAAGGCTGTTCATACGATGCGAGGCGGTCCGGAAAAGCCGGTGGCATGTCCGGTGTGCACGCGGGAGTTCCCCTCGGTACGTTCGTGCAACGCGCACGCGACGCAGGTGCACGGGCCCGGCAAGTTCAAGTGTAAACTGTGCAAGGCCATGCTGCATACTCTGGATGAACGCAAACTCCACTACCTGCTGATCCACCCGGGACGGCATCCGTTCGAGTGCGCGGAGTGCGGCAAGTCGTTCCAATACAAGTCCTCGCTGTATATGCACAAGCAGGACCACCTGCCCAACAAACAGAGCTACACCTGCAACTACTGCTCCAAGGAGTTCGCCAAGAAAGACTCGTTCCGCGAGCATCTACAGATCCACGAGGGTCCGCGGCATGCGTGCTCGTATTGCCCCATGCGGTTCGTGCAGCGGTCGAACATGCTGCGTCACGAGCGACGACACACGGGCGAGCGTCCGTACGCCTGCCCGCACTGTCCACGCACCTTCGCGGATAAGGGCGCGTGCACATCGCACGCTAGGACGCATTCAAAGGAGTCCTCCTACGCCTGCCTCTACTGTGGGCAGACATTTGTGCAAAAGTCAAAGTTGACTTATCACATCAGGAAACATACCGGAGAAAATCTGGAGACGTGTTCGATTTGTTCGAAGCTGTTCACGAGCGCGTGCGCGTTACGCGAGCACATGAAGATCCACCTGTGCAAGAAGGAGTCCGTCAAGTGTCCGCTGTGTGACAAGAAGTACCAGGACGAGCGCTACATGCTGCGTCACCTGCGCACGTCCCACACGCGGTCGCAGTTCTCGTGTCCGATCTGCCAGAAGGTGGTCACCAGCGCCGTGGGCCTGCGACACCACGTCATCACGCACAGCCCGCTCAACACATTCCGCTGTAGAGTCTGTCCAAAGTCATACGCTGTGAAACGGACCATAGTGAAACATTTGCTCCGACGTCATTCGCTGAGCAGTACCGAAGTCAACATCAAGGACTACTACACCAGGCTGGAGCCCCGACAGTGCAAGCTGGACCTGGACGAGGAAACCATGACCAGGGTCTTCGGGCCGCCCAAGAAAAGACCCGATATACTCATAACCGACTTTGTGACGTATACTAAAGACAAGAACACGAAGAAGGAAGCTAAGGACACCAGTGAACACTCGGAGAAGGACAGCGACAGTACAGATAACGAAGCATCACAGAAGAAGATTAAACGGAAGTTTAAAGAGGAGAACCCTGAGGATATGGAACAAGATTTCCAGGAAGGGAACGAGTTGGAGCCGACAGATTTTGTCAGTGTTAAAATTGAACCTATTGAGGATGATGAAATGGAGTAG
Protein Sequence: MASDESDDEPLSVLAAAKKVDPKKFDCEIIPVDEKSSKKRNTSTKKTSLTIKINRRLKTISAPPVIDRPTDVWLYLKDLNPTGPYKCLLCADWFINRSKMVVHYVLNHKKDFCGICRYFVNDRESWKLHVRFHEPWPCSQCVETFPSELSLRQHLSSVHKLVHCRLCHFRLPVGEQYDAHLAQKHNISNVNCKDEECFWEIEDEDLLKFNCCLCSKQHNLSSTFFTHYMGFHHFTLKCITAFISGSDPPFTVHGAEISTQFVDGQLKDLNAFGYVDLEQKPREGVQDKVHTNTTSLSKSMTEIKNETTEGDESKADDSCSNKVMHQVDVEAYEGDDDFDVTLTELIILQKCYFDYIKKILHDISQNLVPVISDINNRNDVVLNVKCPLCDSKFNTGQLFMSHMYKMHNVKSIPSYSCRVCGTNFDSYNELESHIMDEINNFENLWICQFCDKEFGNRETVRRHLTDHWEAIEYDNCFSPHLGFRCKYCPTLFWNETDRERHQVRVHFNKYTDQFYKCNSCSLTFSDKVWYIHHYLENHLKGEKMGSYLLKCCVCCVVLSSIDEMRTHFIDQHPEARKVYCSLDPCKYKPLSQRKSLKLHVKAVHTMRGGPEKPVACPVCTREFPSVRSCNAHATQVHGPGKFKCKLCKAMLHTLDERKLHYLLIHPGRHPFECAECGKSFQYKSSLYMHKQDHLPNKQSYTCNYCSKEFAKKDSFREHLQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACPHCPRTFADKGACTSHARTHSKESSYACLYCGQTFVQKSKLTYHIRKHTGENLETCSICSKLFTSACALREHMKIHLCKKESVKCPLCDKKYQDERYMLRHLRTSHTRSQFSCPICQKVVTSAVGLRHHVITHSPLNTFRCRVCPKSYAVKRTIVKHLLRRHSLSSTEVNIKDYYTRLEPRQCKLDLDEETMTRVFGPPKKRPDILITDFVTYTKDKNTKKEAKDTSEHSEKDSDSTDNEASQKKIKRKFKEENPEDMEQDFQEGNELEPTDFVSVKIEPIEDDEME

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01082695;
90% Identity: iTF_00970643;
80% Identity: iTF_00970643;