Basic Information

Insect: Megathymus violae
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000127.1:268489-272946[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 8.1e-05 0.0074 17.3 2.1 1 23 207 230 207 230 0.97

2 13 1.3 1.2e+02 4.1 4.4 1 23 234 256 234 256 0.97

3 13 1.4e-06 0.00013 22.8 5.1 1 23 261 283 261 283 0.99

4 13 4.3e-06 0.00039 21.3 2.0 1 23 289 311 289 311 0.97

5 13 9.6e-06 0.00087 20.2 0.2 3 23 320 341 319 341 0.97

6 13 0.0023 0.21 12.7 6.4 1 20 347 366 347 369 0.91

7 13 0.018 1.6 9.9 4.1 1 23 375 397 375 398 0.96

8 13 0.0091 0.82 10.8 1.6 1 23 411 433 411 433 0.99

9 13 0.0022 0.2 12.8 5.7 1 23 439 461 439 461 0.97

10 13 4.9e-06 0.00045 21.1 0.7 3 23 469 490 467 490 0.96

11 13 0.23 21 6.4 2.6 2 12 506 516 505 529 0.72

12 13 7e-05 0.0064 17.5 0.3 1 23 529 552 529 552 0.96

13 13 2.3e-05 0.0021 19.0 2.6 1 23 558 581 558 581 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	8.1e-05	0.0074	17.3	2.1	1	23	207	230	207	230	0.97
2	13	1.3	1.2e+02	4.1	4.4	1	23	234	256	234	256	0.97
3	13	1.4e-06	0.00013	22.8	5.1	1	23	261	283	261	283	0.99
4	13	4.3e-06	0.00039	21.3	2.0	1	23	289	311	289	311	0.97
5	13	9.6e-06	0.00087	20.2	0.2	3	23	320	341	319	341	0.97
6	13	0.0023	0.21	12.7	6.4	1	20	347	366	347	369	0.91
7	13	0.018	1.6	9.9	4.1	1	23	375	397	375	398	0.96
8	13	0.0091	0.82	10.8	1.6	1	23	411	433	411	433	0.99
9	13	0.0022	0.2	12.8	5.7	1	23	439	461	439	461	0.97
10	13	4.9e-06	0.00045	21.1	0.7	3	23	469	490	467	490	0.96
11	13	0.23	21	6.4	2.6	2	12	506	516	505	529	0.72
12	13	7e-05	0.0064	17.5	0.3	1	23	529	552	529	552	0.96
13	13	2.3e-05	0.0021	19.0	2.6	1	23	558	581	558	581	0.96

Sequence Information

Coding Sequence: ATGACAGAAATATTTAACTTATACACTCTCTGCCGTTGCTGTCATAGCGATGGAAGCTTCAAGAGTCTTCAGCTTTCCTATGCGTACGACAACCGCATTGAAGTATATTCAACAATGTTGAAGGAAACTTTTGATGTTACGATAAGCCTACCTCCATTTGAAGCAAGCTATGCTATTTGTGATTTTTGCATCAAAAAACTGCGAGATGCAACATGTTTCAAGAGTCAGGTTTTAGAGTGTGAACAGAAGTTTGAGGAATACTGTAAAAATGAACAAGCATTATCTGTCAAAGAGGAAATTGATTATGAGAGCAGTAATGATGGTGACCTAGACAGAGACAAGGATATCAAAAACAATGATGATCAAAGATATGATAAATGCAAAGATGAAAAATGTGATATAAAAGTTATGGAAATTAAAATCAATGGGAATGATGCACCTAATCCTATTCACGAAACGATTCCAATTGAATATATTAAAACCGACAAGGCAAGGGTACTGGTTTCTGAGAGAATTTATAAAAGGCACGGCATTGAAGCTAGAGTTAAAAGAAAACAGATTAATTACCAAGTGGACCCCGAGTTTGAATTACACGTCAATACTGAAGATGGAGATGTGTATATGTGTAAAACGTGTGACAAAAAATATAAAGTGCTCAAACTGTTGCGTAATCATATAATGAAACAACACAGAGACGCTTACAAGTGCCAAATTTGTTCCCTTCAGTGCGTCGGGCGACTCCATTACCTAAGGCACAGCAAAATTCATACCAGTGAGCTTTATAAATGTCAATTTTGTGGGAAATCCTTCCGCAAGAAAAGTTCATTACACCAACATCTGAATGTTCATACGAAAACCGAGAAGTTTCAATGTGATATATGCCATAAAATATTTGCTTACAAGCAGACTTTGAGAAAACATATCCTATGGCATTATGGTGCAACAAAAAAACGCATATGCGACGTATGCGGGCACGCTTTCAACGACATGGCGAACCTCAACAGCCACATTAGAACGGTACATGAGAAACAACGACCTTTCAAATGTCACCTGTGTCCGAAAACGTTCACAGCGAATAAACATTTGAAAGAACATTCATTTTTTCACACTGGAGAAAGGCCTTATAAATGCGACATGTGTACCGATGGCTTTGTTTCGCCATGGAAGTTAAAACACCATCAATTCAAACACCATCCAAAGTCCAGCGTGGTCGCTCAGGCGAAGAAGCTGTACACCTGCAAGGTGTGTAAGCTGGAGCTAGACACGCGGGGGAAATTTATGTCTCACTTAAAAAGACATGTAGGTCAGAAGGAATACAAGTGCCATTTGTGTACGAAGGATTTTACATGCAAATACTCCCTAAACCGTCATATTATCGCGCACAGCGGCATCAAGGCGTACGGTTGTGATATGTGCGACAAGAAATACACTCAACCCTCACAACTGTGGCGTCACAAGAAAAGAATTCACGATCCGAACAGTTTAGCTTACCCCGGCCGCATCGTAGAACGCATCAAGTGTGATCTATGTAACAAAAGCTTTAAAGATATAGAAAAGCATTTAATATCGCACAAGACAAGACCGCATGTCTGTCAAATTTGCTCGAAATCTTATCCAGAGAGGAACACCTTGAATAGACACATACTAATCGTACACCAGGGAGTCAGGCGGCATCCTTGTACCCTCTGTGATAAAAAGTATACTAAATGGACAGGTTTACAAAAACATACCAGGAAAGTACATAAGCTGGAGTTGAAGAAGGAAGTAGAAGAGTCTTGA
Protein Sequence: MTEIFNLYTLCRCCHSDGSFKSLQLSYAYDNRIEVYSTMLKETFDVTISLPPFEASYAICDFCIKKLRDATCFKSQVLECEQKFEEYCKNEQALSVKEEIDYESSNDGDLDRDKDIKNNDDQRYDKCKDEKCDIKVMEIKINGNDAPNPIHETIPIEYIKTDKARVLVSERIYKRHGIEARVKRKQINYQVDPEFELHVNTEDGDVYMCKTCDKKYKVLKLLRNHIMKQHRDAYKCQICSLQCVGRLHYLRHSKIHTSELYKCQFCGKSFRKKSSLHQHLNVHTKTEKFQCDICHKIFAYKQTLRKHILWHYGATKKRICDVCGHAFNDMANLNSHIRTVHEKQRPFKCHLCPKTFTANKHLKEHSFFHTGERPYKCDMCTDGFVSPWKLKHHQFKHHPKSSVVAQAKKLYTCKVCKLELDTRGKFMSHLKRHVGQKEYKCHLCTKDFTCKYSLNRHIIAHSGIKAYGCDMCDKKYTQPSQLWRHKKRIHDPNSLAYPGRIVERIKCDLCNKSFKDIEKHLISHKTRPHVCQICSKSYPERNTLNRHILIVHQGVRRHPCTLCDKKYTKWTGLQKHTRKVHKLELKKEVEES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00970607;
90% Identity: iTF_00970607;
80% Identity: -