Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000127.1:268489-272946[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 8.3e-05 0.0064 17.2 2.1 1 23 223 246 223 246 0.97

2 13 1.3 1e+02 4.0 4.4 1 23 250 272 250 272 0.97

3 13 1.5e-06 0.00011 22.8 5.1 1 23 277 299 277 299 0.99

4 13 4.4e-06 0.00034 21.2 2.0 1 23 305 327 305 327 0.97

5 13 9.8e-06 0.00075 20.2 0.2 3 23 336 357 335 357 0.97

6 13 0.0024 0.18 12.6 6.4 1 20 363 382 363 385 0.91

7 13 0.018 1.4 9.9 4.1 1 23 391 413 391 414 0.96

8 13 0.0093 0.71 10.8 1.6 1 23 427 449 427 449 0.99

9 13 0.0022 0.17 12.7 5.7 1 23 455 477 455 477 0.97

10 13 5.1e-06 0.00039 21.1 0.7 3 23 485 506 483 506 0.96

11 13 0.24 18 6.4 2.6 2 12 522 532 521 545 0.72

12 13 7.2e-05 0.0055 17.4 0.3 1 23 545 568 545 568 0.96

13 13 2.3e-05 0.0018 19.0 2.6 1 23 574 597 574 597 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	8.3e-05	0.0064	17.2	2.1	1	23	223	246	223	246	0.97
2	13	1.3	1e+02	4.0	4.4	1	23	250	272	250	272	0.97
3	13	1.5e-06	0.00011	22.8	5.1	1	23	277	299	277	299	0.99
4	13	4.4e-06	0.00034	21.2	2.0	1	23	305	327	305	327	0.97
5	13	9.8e-06	0.00075	20.2	0.2	3	23	336	357	335	357	0.97
6	13	0.0024	0.18	12.6	6.4	1	20	363	382	363	385	0.91
7	13	0.018	1.4	9.9	4.1	1	23	391	413	391	414	0.96
8	13	0.0093	0.71	10.8	1.6	1	23	427	449	427	449	0.99
9	13	0.0022	0.17	12.7	5.7	1	23	455	477	455	477	0.97
10	13	5.1e-06	0.00039	21.1	0.7	3	23	485	506	483	506	0.96
11	13	0.24	18	6.4	2.6	2	12	522	532	521	545	0.72
12	13	7.2e-05	0.0055	17.4	0.3	1	23	545	568	545	568	0.96
13	13	2.3e-05	0.0018	19.0	2.6	1	23	574	597	574	597	0.96

Sequence Information

Coding Sequence: atgacagaaatatttaacttatacaCTCTCTGCCGTTGCTGTCATAGCGATGGAAGCTTCAAGAGTCTTCAGCTTTCCTATGCGTACGACAACCGCATTGAAGTATATTCAACAATGTTGAAGGAAACTTTTGATGTTACGataagcCTACCTCCATTTGAAGCAAGCTATGCTATTTGTGATTTTTGCATCAAAAAACTGCGAGATGCAACATGTTTCAAGAGTCAGGTTTTAGAGTGTGAACAGAAGTTTGAGGAATACTGTAAAAATGAACAAGCATTATCTGTCAAAGAGGAAATTGATTATGAGAGCAgtAATGATGGTGACCTAGACAGAGACAAGGATATCAAAAACAATGATGATCAAAGATATGATAAATGCAAAGATGAAAAATGTGATATAAAAGTTatggaaattaaaatcaatggGAATGAcgatgttaatgaaaaatatcgtgtaaaaataaaagaagaaaatgaaGATGCACCTAATCCTATTCACGAAACGATTccaattgaatatattaaaaccgACAAGGCAAGGGTACTGGTTTCTGAGAGAATTTATAAAAGGCACGGCATTGAAGCTAGAGTTAAAAGAAAACAGATTAATTACCAAGTGGACCCCGAGTTTGAATTACACGTCAATACTGAAGATGGAGATGTGTATATGTGTAAAACgtgtgacaaaaaatataaagtgcTCAAACTGTTGCGTAATCATATAATGAAACAACACAGAGACGCTTACAAGTGCCAAATTTGTTCCCTTCAGTGCGTCGGGCGACTCCATTACCTAAGGCACAGCAAAATTCATACCAGTGAgctttataaatgtcaattttgtGGGAAATCCTTCCGCAAGAAAAGTTCATTACACCAACATCTGAATGTTCATACGAAAACCGAGAAGTTTCAATGTGATATATGccataaaatatttgcttacAAGCAGACTTTGAGAAAACATATCCTATGGCATTATGGTGCAACAAAAAAACGCATATGCGACGTATGCGGGCACGCTTTCAACGACATGGCGAACCTCAACAGCCACATTAGAACGGTACATGAGAAACAACGACCTTTCAAATGTCACCTGTGTCCGAAAACGTTCACAGCGAATAAACATTTGAAAGAACATTCATTTTTTCACACTGGAGAAAGGCCTTATAAATGCGACATGTGTACCGATGGCTTTGTTTCGCCATGGAAGTTAAAACACCATCAATTCAAACACCATCCAAAGTCCAGCGTGGTCGCTCAGGCGAAGAAGCTGTACACCTGCAAGGTGTGTAAGCTGGAGCTAGACACGCGGGGGAAATTTATGTCTCACTTAAAAAGACATGTAGGTCAGAAGGAATACAAGTGCCATTTGTGTACGAAGGATTTTACATGCAAATACTCCCTAAACCGTCATATTATCGCGCACAGCGGCATCAAGGCGTACGGTTGTGATATGTGCGACAAGAAATACACTCAACCCTCACAACTGTGGCGTCACAAGAAAAGAATTCACGATCCGAACAGTTTAGCTTACCCCGGCCGCATCGTAGAACGCATCAAGTGTGATCTATGTAACAAAAGCTTTAAAGATATAGAAAAGCATTTAATATCGCACAAGACAAGACCGCATGTCTGTCAAATTTGCTCGAAATCTTATCCAGAGAGGAACACCTTGAATAGACACATACTAATCGTACACCAGGGAGTCAGGCGGCATCCTTGTACCCTCTGTGATAAAAAGTATACTAAATGGACAGGTTTACAAAAACATACCAGGAAAGTACATAAGCTGGAGTTGAAGAAGGAAGTAGAAGAGTCTTGA
Protein Sequence: MTEIFNLYTLCRCCHSDGSFKSLQLSYAYDNRIEVYSTMLKETFDVTISLPPFEASYAICDFCIKKLRDATCFKSQVLECEQKFEEYCKNEQALSVKEEIDYESSNDGDLDRDKDIKNNDDQRYDKCKDEKCDIKVMEIKINGNDDVNEKYRVKIKEENEDAPNPIHETIPIEYIKTDKARVLVSERIYKRHGIEARVKRKQINYQVDPEFELHVNTEDGDVYMCKTCDKKYKVLKLLRNHIMKQHRDAYKCQICSLQCVGRLHYLRHSKIHTSELYKCQFCGKSFRKKSSLHQHLNVHTKTEKFQCDICHKIFAYKQTLRKHILWHYGATKKRICDVCGHAFNDMANLNSHIRTVHEKQRPFKCHLCPKTFTANKHLKEHSFFHTGERPYKCDMCTDGFVSPWKLKHHQFKHHPKSSVVAQAKKLYTCKVCKLELDTRGKFMSHLKRHVGQKEYKCHLCTKDFTCKYSLNRHIIAHSGIKAYGCDMCDKKYTQPSQLWRHKKRIHDPNSLAYPGRIVERIKCDLCNKSFKDIEKHLISHKTRPHVCQICSKSYPERNTLNRHILIVHQGVRRHPCTLCDKKYTKWTGLQKHTRKVHKLELKKEVEES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00971558;
90% Identity: iTF_00971558;
80% Identity: -