Mvio017863.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megathymus violae
Gene Symbol
-
Assembly
GCA_003671415.1
Location
PDGT01000086.1:252711-262643[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 8.6e-05 0.0079 17.2 0.1 3 23 133 153 132 153 0.97
2 18 7.8e-07 7.1e-05 23.6 1.2 1 23 159 181 159 181 0.99
3 18 4.9e-06 0.00044 21.1 2.7 1 23 187 209 187 209 0.99
4 18 8.6e-06 0.00079 20.3 2.2 1 23 224 246 224 246 0.98
5 18 0.00022 0.02 15.9 0.6 1 23 261 283 261 283 0.98
6 18 4.5e-05 0.0041 18.1 3.1 1 23 298 320 298 320 0.98
7 18 3.1e-07 2.8e-05 24.9 1.5 1 23 335 357 335 357 0.99
8 18 0.00014 0.013 16.6 2.8 1 23 363 385 363 385 0.98
9 18 9.7e-06 0.00088 20.2 2.1 1 23 391 413 391 413 0.99
10 18 0.031 2.9 9.1 1.8 1 23 420 442 420 442 0.98
11 18 5.2e-07 4.8e-05 24.2 2.3 1 23 448 470 448 470 0.99
12 18 0.036 3.3 8.9 1.8 1 23 477 499 477 499 0.98
13 18 2.1e-06 0.0002 22.2 1.5 1 23 505 527 505 527 0.99
14 18 0.00011 0.0097 16.9 0.7 1 23 534 556 534 556 0.99
15 18 2.4e-06 0.00022 22.1 1.9 1 23 562 584 562 584 0.98
16 18 0.0017 0.16 13.1 0.3 1 20 590 609 590 612 0.93
17 18 3.3e-05 0.003 18.5 1.4 2 23 619 640 618 640 0.96
18 18 3.1e-06 0.00028 21.8 1.4 1 23 646 669 646 669 0.97

Sequence Information

Coding Sequence
ATGTTCGAACAACAAATTAAAGCTGAACCCATGAGTTTTTACTCGTCTCATCCACATGTACACCCTGGCCCCCCAGCAATAGTTCGACCTGACTCAAATCATTCTATCATCAACATGAATCAACATCATCTCTCTCATGAAGATTCTAAGGATAGTCTCATAGTACAACAACAAGTACAACATCAGGAGCTGCTGGAACAGCATCAACAAGATATGCAACAAGATGATGATGTAGATAATTTGAGCTTCAAAGGAATGGAAGATGATGGAGTTGACATGGATATGGATGGTCGACAGTGTTCACAGGGCATGGGTGTCGATATGGGATCAGTTCAAACTAAGATGGAAATGTCAAATGGAGGAGGGCAATCAGTACCGCGGTCGAAGCCACAGGCCTGCAAGGTTTGTGGTAAAGTTTTATCATCAGCTTCTTCGTATTACGTCCACATGAAGCTTCATTCGGGAAATAAACCCTTTCAATGCACGGTTTGCGATGCAGCTTTTTGCCGCAAACCGTACCTCGAGGTACATATGCGCACTCATACAGGCGAGAGGCCCTTCCAATGCGACCTATGCCTCAAAAGATTCACACAAAAGTCCAGTCTCAACACGCACAAACGGGTCCACACCGATGAGCACATGCGCGCGTTGATGGCGAAGGAGCGGCCCTACAGATGTGAGCTCTGTCAGATGCAGTTCACGCAGAGCTCCAGCCTCAACCGTCACAAGAAAATACACACGGAGGAACACAGACGCGCTCTGCTGGCTAAGGAACGTCCCTACCAGTGCGCCGTCTGCTTTGTGAGGTTCACCCAGAGATCTAGTTTGGGCCGGCACGAGAAAATACATACTGAGGAACACAGACGAGCCCTGTTAGAGAAAGTGCGGCCGTACCAGTGCCACATCTGTTTTATGCGCTTCACTCAGAAGTCCAGCCTGGGCCGACACGGGAAAATACACACTGAGGAGCACATCCAATCGCTGATCAACAAAGTGCGCCCATATCAGTGCGACATCTGTGACAAGCGGTTCACTCAGAAGTCCAGCCTTGGCACTCATAAACGTATTCATACTGGGGAGCGGCCGTTCCAGTGCACCGTCTGCCTCAAGTCCTTCACGCAGAAGTGCGCGCTCAATTTGCACGAAAAAATACATACGGGCGAGCGGCCCTATCAGTGCGACGCCTGTCTCAAGCGCTTCACGCAGAAGTCCAGCCTCAATATACATAAACGGACGCACACAGTCCAGGGCAGACCGTTCCAGTGCCTGTCGTGTCCGGCCGCCTTCACCTGCAAGCAATACCTGGAGATTCACACGCGGACGCACACGGGCGAGCGGCCGTATCAGTGCGACATCTGCCTGAAGCGCTTCACTCAGAAGTCAAGTCTCAACATACACAAACGGACGCACTCAGTGCAAGGACGGCCCTTCCAGTGCCTGCAGTGTCCGGCCGCCTTCACCTGCAAGCAGTACCTCGAGATCCATAACCGTACGCACACGGGCGAGCGGCCTTACCAGTGTGACGTTTGTCTCAAGAGATTCGCGCAAAAGTCTACACTCAACATACATAAAAGAACGCACACAGTGCAAGGGCGGCCGTATCAATGTTCGGAGTGTCCCGCGGCGTTCACTTGCAAGCCGTACCTGGAAATACACATGCGAACGCACACTGGCGAACGGCCCTTCGAGTGCGATGTCTGTTACAAACGCTTCACGCAGAAATCCACACTCAACATTCACAAGCGAATCCACACCGGTGAACGCCCATACGCTTGTGACATTTGTCAAAAGAGATTTGCTGTTAAAAGTTACGTGACGGCACACAGATGGTCGCACGTGGCCGACAAGCCGCTAAACTGCGATCGGTGCTCGATGACGTTCACGTCGAAGTCGCAGTTCGCGCTTCACATCCGCACGCATTCGGCCGGCTCGTGCTACGAGTGTAGCGTGTGCGGACGTACCTTCGTGCGAGACAGCTATCTCATTAGGCACCACAACCGGGTGCACCGCGAGAATCACAGTAACGTGTCGGCGAACAGCATGAGCGGACTTAACAATGTCGCCACCAATACTAACTCCAACAACGGCAACTATGACTCCCCCGGCGTTTGTGACTTAAGTTTCGTGCCAATGGTAAATCGCTACATGACCTCCCAGGGCACACAGGTGTCTATGCAGGACACGCACAGCAAATTGTCCGCAATGTCGCCGCAATCCATCGCATCTATTTCGTCTCCTCCTCCCCCGCACACCCCCACACCCCAGCCGCAGATGTCGGGCCAGATGCGTCTCACCGACTGA
Protein Sequence
MFEQQIKAEPMSFYSSHPHVHPGPPAIVRPDSNHSIINMNQHHLSHEDSKDSLIVQQQVQHQELLEQHQQDMQQDDDVDNLSFKGMEDDGVDMDMDGRQCSQGMGVDMGSVQTKMEMSNGGGQSVPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMAKERPYRCELCQMQFTQSSSLNRHKKIHTEEHRRALLAKERPYQCAVCFVRFTQRSSLGRHEKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTGERPFQCTVCLKSFTQKCALNLHEKIHTGERPYQCDACLKRFTQKSSLNIHKRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLQCPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCSECPAAFTCKPYLEIHMRTHTGERPFECDVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSAGSCYECSVCGRTFVRDSYLIRHHNRVHRENHSNVSANSMSGLNNVATNTNSNNGNYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDTHSKLSAMSPQSIASISSPPPPHTPTPQPQMSGQMRLTD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01246112;
90% Identity
iTF_00970588;
80% Identity
iTF_00970588;