Mvio003060.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megathymus violae
Gene Symbol
Hr39
Assembly
GCA_003671415.1
Location
PDGT01000046.1:742671-757896[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 0.24 3.2e+03 -2.2 2.8 33 125 138 234 44 245 0.63
2 5 2 2.7e+04 -6.4 10.5 65 192 209 337 138 364 0.51
3 5 3.4e-08 0.00046 20.3 0.1 1 23 441 463 441 486 0.80
4 5 1.2e-36 1.6e-32 114.0 0.0 125 316 475 651 463 652 0.85
5 5 3e-13 4.2e-09 36.9 0.0 342 408 651 723 650 723 0.88

Sequence Information

Coding Sequence
ATGAACGCCGCGATGTCTAGCGAGGGAGAGGCGGTGAAGATTGAGGGTGGTCATGTGTCAGTTACTACCATCAGCATGGCTGGGCCGGAAGCCAGTAATGGTCAGTTCTCGTACAGCTCGAGCGGAGTACGCATCAGCGTGTCCTCGGAGCCTCACGACGAAGACTCCACTGACGCGGAAGTCTCCAAAATCGACTTTACGCAACACCAGTATGAGGTGAATATGCGTAACAAGAAGAAGCGCTCGTCCAGCGGACATTGCGATCAGAGTGAACAGGAGCGGCCCATGTCGTGGGAAGGCGAACTGTCCGACTCTGAGGAGATGGTCATAGATACCAACGCCAACAATGATGAAAACAGCAGCATGCTAGACCTGCAGTCGTCAAGGGACTCCATCGACACTCTTCGCAACGTGACGATCAAGACGGAGCCTTTGAAGAGCGAGGTCTTTCAGAGCTTGGATGACCAGAGGGTGCTCGACTTGAAATACGCCTCGCCGTTGCAGTCGCATCAGAGGAGTCTCAGTATGAACAGGATATCAGTGTTGACGGACAATGCGTCCCTCTCGCTGCCCCGCCGGCCGACCTCCCCGACGAACAGCGCCAAGTCGCTAGCGCTCTCCGACCAGTACGAGCAGCACTCGATGCCGTTGATGACGCAGAACTCCAACACCGAGATCCAGAATTTGACTATCAAAAAGGAAACGCAGTTGTCAGAATTAAAATGTGAGCCAGCTGTGGGCATGGATAAGTTACTAGGCCTCCATGGATCCCCACTGCTGGGGCGGCTGCCGCGGGTGCAGTCCAGTGCTAGTACGGATTCGGCCGTACATTCTATGTATACGCACAGTCCGTCGGCGAGCCCGCGGCCGGCGCGCCACTACACGCCGTCGCTGTCGCGCAACAACAGCGACGCGTCGCACTCCTCCTGCTACTCGTACAGCTCCGAGTTCTCGCCCACGCACTCGCCGGTGCAGGGTCGGCATCCGCACGTGGTGTACAGGGAAGCGGCGGTGTTCCCCGCCTCGCCGGCACAGGAGGAGGACGCGGAGACGGCCGAGGAACGACTCCATCACCACCAGGGGATCAGTAGGCAGCAACTTATTAACAGCCCATGTCCGATCTGCGGGGACAAGATTAGCGGGTTTCATTACGGGATATTCTCGTGCGAGTCGTGCAAGGGGTTCTTCAAGAGGACGGTCCAGAACCGCAAAAATTACATGTGCCTGCGCGGGGGCAACTGTCCTGTGACGGTGGCCACTAGGAAGAAATGTCCGGCTTGTAGGTTCGACAAGTGTCTCGGCTGTGGGATGAAACTGGAAGCTATCCGCGAGGACCGCACGCGCGGCGGCCGCTCCACCTACCAGTGCTCGTACTCGCTGTCGGGCGCCGCGTCCACCGGCTCGCTGCTCTCGGCGCACGCGCACGCTCACGCACACGCCGCCACCTCGCTGCGGCACGCCACCAGCCTCACCTCGGTAAACGGTCCGACATCGTATAACAGTCGAGGGGAGTCCAGCAACAGCCGACTCACGCCTGACATACCACCGCTGTTACAGGAGATAATGGACCGGGGGCGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGCGCAGAACTCGAGCGCCGACTTCCTGGCCGACCTGTGCAACATCGCCGACCACAGGCTGTACAAGATCGTCAAGTGGTGTAAGAGCTTGCCGCTCTTCAAAAACATCTCGATCGACGACCAGATCTGCCTGCTGATAAACAGCTGGTGCGAGCTGCTGGTGCTGTCGTGCTGCTACCGCGGCGTGGGCACGCCGGGCGAGGTGCGCGTGGGCGGCCCGCGCGGCATCACGCTGCACCAGAGCGCCAAGTACGGGCTGACGCCGTGCATAGAACGAATGCTGAGCTTCACGGACCACCTGCGGCGGCTGCGGGTCGACCGGTACGAATACGAGAAGGCGCTGGCGGCGCTGCAGGCGTACACCGCGGCGCACTCGCCCGACGCGCCCGCCAAGTTCGGCGAGCTGCTGCTGCGCATCCCCGAGCTGCAGCGCACCTGCCAGTTCTTCATGCAAGTCGGCAAGGAGATGCTCAATCCAGCGAACAAGGGCAAAGACGGCGAAGGGCCGAGCTTCAACCTGCTCATGGAACTACTGAGAGGGGACCACTGA
Protein Sequence
MNAAMSSEGEAVKIEGGHVSVTTISMAGPEASNGQFSYSSSGVRISVSSEPHDEDSTDAEVSKIDFTQHQYEVNMRNKKKRSSSGHCDQSEQERPMSWEGELSDSEEMVIDTNANNDENSSMLDLQSSRDSIDTLRNVTIKTEPLKSEVFQSLDDQRVLDLKYASPLQSHQRSLSMNRISVLTDNASLSLPRRPTSPTNSAKSLALSDQYEQHSMPLMTQNSNTEIQNLTIKKETQLSELKCEPAVGMDKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSPSASPRPARHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQGRHPHVVYREAAVFPASPAQEEDAETAEERLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLSAHAHAHAHAATSLRHATSLTSVNGPTSYNSRGESSNSRLTPDIPPLLQEIMDRGRXXXXXXXXXXXXXXXAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGPRGITLHQSAKYGLTPCIERMLSFTDHLRRLRVDRYEYEKALAALQAYTAAHSPDAPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKGKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00985246;
90% Identity
iTF_00971466;
80% Identity
iTF_00971466;