Basic Information

Insect: Megathymus ursus
Gene Symbol: -
Assembly: GCA_003671415.1
Location: PDGT01000093.1:678522-704955[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.005 0.38 11.7 0.9 1 23 142 165 142 165 0.90

2 19 0.015 1.2 10.1 1.0 2 23 191 213 190 213 0.95

3 19 0.018 1.4 9.9 6.2 2 23 236 257 236 257 0.98

4 19 0.00056 0.042 14.6 0.2 1 20 261 280 261 282 0.95

5 19 0.00045 0.034 14.9 2.0 1 23 290 313 290 313 0.97

6 19 0.0017 0.13 13.1 1.3 1 23 487 510 487 510 0.88

7 19 0.018 1.3 9.9 0.4 1 23 590 612 590 612 0.96

8 19 0.071 5.4 8.0 3.0 2 23 619 640 618 641 0.92

9 19 0.015 1.1 10.2 0.3 1 13 715 727 715 729 0.89

10 19 3.4 2.6e+02 2.7 7.9 1 23 862 885 862 885 0.92

11 19 0.32 24 6.0 0.2 2 23 912 934 911 934 0.95

12 19 0.025 1.9 9.4 0.7 2 23 957 978 956 978 0.97

13 19 0.09 6.8 7.7 0.3 1 23 982 1004 982 1004 0.97

14 19 0.0014 0.1 13.4 1.5 1 23 1009 1032 1009 1032 0.95

15 19 4.9 3.7e+02 2.2 5.6 2 23 1040 1062 1039 1062 0.89

16 19 0.00012 0.0089 16.8 1.0 1 23 1069 1092 1069 1092 0.98

17 19 0.0023 0.17 12.7 0.3 1 23 1098 1120 1098 1120 0.97

18 19 5e-07 3.8e-05 24.2 2.4 1 23 1126 1148 1126 1148 0.99

19 19 0.00043 0.033 15.0 1.3 1 23 1154 1177 1154 1177 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.005	0.38	11.7	0.9	1	23	142	165	142	165	0.90
2	19	0.015	1.2	10.1	1.0	2	23	191	213	190	213	0.95
3	19	0.018	1.4	9.9	6.2	2	23	236	257	236	257	0.98
4	19	0.00056	0.042	14.6	0.2	1	20	261	280	261	282	0.95
5	19	0.00045	0.034	14.9	2.0	1	23	290	313	290	313	0.97
6	19	0.0017	0.13	13.1	1.3	1	23	487	510	487	510	0.88
7	19	0.018	1.3	9.9	0.4	1	23	590	612	590	612	0.96
8	19	0.071	5.4	8.0	3.0	2	23	619	640	618	641	0.92
9	19	0.015	1.1	10.2	0.3	1	13	715	727	715	729	0.89
10	19	3.4	2.6e+02	2.7	7.9	1	23	862	885	862	885	0.92
11	19	0.32	24	6.0	0.2	2	23	912	934	911	934	0.95
12	19	0.025	1.9	9.4	0.7	2	23	957	978	956	978	0.97
13	19	0.09	6.8	7.7	0.3	1	23	982	1004	982	1004	0.97
14	19	0.0014	0.1	13.4	1.5	1	23	1009	1032	1009	1032	0.95
15	19	4.9	3.7e+02	2.2	5.6	2	23	1040	1062	1039	1062	0.89
16	19	0.00012	0.0089	16.8	1.0	1	23	1069	1092	1069	1092	0.98
17	19	0.0023	0.17	12.7	0.3	1	23	1098	1120	1098	1120	0.97
18	19	5e-07	3.8e-05	24.2	2.4	1	23	1126	1148	1126	1148	0.99
19	19	0.00043	0.033	15.0	1.3	1	23	1154	1177	1154	1177	0.97

Sequence Information

Coding Sequence: ATGAACTCACCAGTGGACGTACCTGAAATCATTCTTCAGATGGTCAAGTCGGAGACTAGCACGAGGGTTAAAAAGGAGCCAGATGAGGACAGTGATGTTGATAACGAGTCCTGTGAGTCTGCAGATCGAAAAGACATTCAAAGCAAAGATCATGAAGgcAAAATCGGAGTGATTAATGAACGGCCAGTTATAGAAAACATACAGACGATCCCAGAATATGACTTAGAAAACAGTGCTTTAATGGCCGAGAACAATgatgaaagtttaaataaagACATTGAAATGACCGCAAGCAACGAGCAAAAGTTATCCTTACCTGACGACGGCGAATTGTTATCGCAACAGGATAGGTATTTTTCTAACATAAGTCTTATTTTGAACTGTACAAACGCAACTTTGCTGTATTCACAAGAATTATTCGGGTACATATGTTACTTTTGCAATAGATACTTCGAAACCCCTTCGAAACTCAAGGAACACGCGTTAGATACGCACAAAATTATACCCAAATTGGAAATTTACAGAAGCTATCACCTGCGTAACGTTGATAAACTCGATATCACTGGTTTACGCTGTAAGCTTTGcgatacatattttaacaaccTTGAGAAAATGAAAGACCACTTAGAAAAAGATcacaacaaacatttttactttgaaaCGGAGACACGAACAATTCCTTTACTATTCAATGAAGAGACACCTCAATGCTGCTATTGCAAGGAAGAATTCGACAATTGCCAAGCTCTGACAAAGCATACGAGGAGTCATTACAGAAATTACGTTTGCAGCGTATGTGACTTGGGTTTCGTTAGTAGGAAACAACTGATACATCACATAACGAATAACGAAAAAGATCACGGAAGTTTCAAATGTAACATATGTTCAGAGCCATTCAACAATTGTGAAACGCTCAAAGAACACGAAAAGATATACCATGACGAAGTGTACCAAGGTAATTACAGCAACAAGGTATATAGGTCTCGGGATATAAAAGACAAGCGGCGTTTAACTCTCTTCAAGGCACAATGTGctgtttttaaaaatcctaTAAGTGAACTTACCAGTTCTACGTTACAAAGTTCGACTTCTGCAAATGACAGTGGTAACACTACGAGAGAATACATTGATGTTGCAAGTGAAATCACTGATAGATTGAATGTAAGGCCGGAGCCAGTGTCTGTTGACATTAGAAACTGTAAGAATGATGTGGCTTATAACTCAGGTGAAGCTGAAGAAATAAGTGAAAGTAAAATTGACCCTGGTAGAGAGACTAGTAAAAAAGGTAATCAAATTTCGGGAAAGACGGAAAAGAGAAGAGAAGAGGATCCATATATGTTGAGAAATTCACTCATAGCCAAAGGGCTGTGTAcagaaaatgaaaaacatttctATAACCTTAAAGTGATATTGGAAAGCACAAACGCTACTTTAATTCGGGAAAAACGTGGAAATTTATTCGCGTGTTACTTTTGCAATAAATCTTACGAAAATCCAGAGGATTTGAAAAAACACAACACCAATTCACATATGTCTCTTAATCGAGTGGATTTTAAAATTCCAGTCGGCCACCGTATAGTTGTAGCGCACCTCGACACAACTGACCTTTATTGTAAACTTTGCAAcgttaatattgataattttctgGAATTATTTAATCACTTAAGCGAAGTCCATCAAAGAGCGTTGTTCGATGAAATGAAGAATCAAATATTAGCTTTTAAATTCACTTATTACTTGAATGCGGCAAATGAAAAAGTCTACAGGTATCTGTGTGATCTGTGTAATAGAGAATTCGGAACAAGGAACGCTATAAAATATCACGTAAATACTCATTACGAGTTTACAATGACCAGTTGTGGTTTTTGCAACGAAAGCTTTAGCAATTCGAAATTGAAAGAACTTCATATGACATTTCATCACAATGTTCGGAAATTAAATGACAATGTCAAACCCAGAGATGGTGTTGAATCTACAAATCCAATCAAAGATTCAAATAAACGCGTCGCACCGACAAACGAACGCATCAATTTGACAAAAGAACGCGTTGCACCGACAAACGAATACGTCGATTTGACAAATGAATGCGTCGAATCGAGTCAGAAACGTCTTAAACGTACGGATGAAGGTCCCAAACAAATGcataaatgtcatatttgcgATAAAGCATTTCCGTCTCCAAAAGCCTCTTTCAAAATGGAAtgtgagaataaaaaaaatattcataaaatgcaTAATGAAACTGTTGATATTGGTGATACCAATGATGATATTCATCAGATCATAAGTTATAATATGCAAGAAAATGcacaaattcaaaatgaaaagTGGAACATACCAAAAGATCCGAATCAAAGCACAGAACAAATCTGTGAACAGTGCATAGCAAGGCTGAAGGACGCAATAAGCTTCAAGGCGGAAGTGCTGGCATCGACGAGGGTTTTGGAAAACCTTGGCAAGCCACGGCCTGTGAAGAAGAAAGGAGACGAAGGCCCACAGGAAATGGTGAAGCATACAACAAACATCCTCACTATCATGGAGAACTCCAATGCGACGCCCATCCGTTGCCATGGTGACGGGGGCTACATGTGTTGTTTCTGCAACCACCAGTACCAGAATCCGGACGATCTGAAGAACCACACATTGTTCTGTCATGATTTCAAGACAAAAAGAACACTCACCAAAGGTAAACGGCCGTCTTCGTACTTCGTGAAGCTGGATATATCCTATCTGAAATGCACCATTTGCAATACGGACATGAatactttagaaaaattaatagaacACTTAATTAAAGACCATCAGAAACCCATGTATATGGACATTAAAAACCATATATTACCGTTTAGATTTGAGAGTGAAGAACTGAAGTGTACAGTGTGTTCGAACGTTTACAACAAGTTCAAGCTATTGCAGGAACATTTGAATGTACATTATCAGAATTATGTGTGTGAAGTGTGTAAcgcgggtttcgtttcacgaaTGATCCTCCACAATCATACAAGGGGGCATAAAACCGGTGTGTTCACGTGTGAAATTTGCCTAAAAGTGTATTCGACGCGTCGGAAACTAACTTATCATAAGAATTTAGTGCATCGACATTCGTATTTAGTGAGCAAGTGCGGTTATTGCCATCAGAAGTTCAAATCGTATCACCGGAAGTTGGAACATTTGACAAAAGTACACAACGTCAAGCCAATGACTTATACCTGTAAAGCTTGTAACAGAAATTTTAATAGCCAAGCGGCGTTAAGGGTGCACAGGAAACGCGATCACCTGATGGAGAGGAAGTACAAGTGTACAGAATGTGACATGGAATTCTTCGCCAGAGCTGAACTGAACGCTCATTCCTTGAAGCATACAGGGTTGAGAGAGTTCCAGTGCGATGTTTGCCAGAAGATGTTCAAGAGGAAGTTCACGCTGACTGAACATATGCGGATACACGAGAATAATTGCAGATTTAAATGCGAGCTGTGCGGTGCAGCGTTTGTGCAGAAGTGCAGCTGGAGGGGACATATGCGGAACAAACATGGGATCATCAGCTGA
Protein Sequence: MNSPVDVPEIILQMVKSETSTRVKKEPDEDSDVDNESCESADRKDIQSKDHEGKIGVINERPVIENIQTIPEYDLENSALMAENNDESLNKDIEMTASNEQKLSLPDDGELLSQQDRYFSNISLILNCTNATLLYSQELFGYICYFCNRYFETPSKLKEHALDTHKIIPKLEIYRSYHLRNVDKLDITGLRCKLCDTYFNNLEKMKDHLEKDHNKHFYFETETRTIPLLFNEETPQCCYCKEEFDNCQALTKHTRSHYRNYVCSVCDLGFVSRKQLIHHITNNEKDHGSFKCNICSEPFNNCETLKEHEKIYHDEVYQGNYSNKVYRSRDIKDKRRLTLFKAQCAVFKNPISELTSSTLQSSTSANDSGNTTREYIDVASEITDRLNVRPEPVSVDIRNCKNDVAYNSGEAEEISESKIDPGRETSKKGNQISGKTEKRREEDPYMLRNSLIAKGLCTENEKHFYNLKVILESTNATLIREKRGNLFACYFCNKSYENPEDLKKHNTNSHMSLNRVDFKIPVGHRIVVAHLDTTDLYCKLCNVNIDNFLELFNHLSEVHQRALFDEMKNQILAFKFTYYLNAANEKVYRYLCDLCNREFGTRNAIKYHVNTHYEFTMTSCGFCNESFSNSKLKELHMTFHHNVRKLNDNVKPRDGVESTNPIKDSNKRVAPTNERINLTKERVAPTNEYVDLTNECVESSQKRLKRTDEGPKQMHKCHICDKAFPSPKASFKMECENKKNIHKMHNETVDIGDTNDDIHQIISYNMQENAQIQNEKWNIPKDPNQSTEQICEQCIARLKDAISFKAEVLASTRVLENLGKPRPVKKKGDEGPQEMVKHTTNILTIMENSNATPIRCHGDGGYMCCFCNHQYQNPDDLKNHTLFCHDFKTKRTLTKGKRPSSYFVKLDISYLKCTICNTDMNTLEKLIEHLIKDHQKPMYMDIKNHILPFRFESEELKCTVCSNVYNKFKLLQEHLNVHYQNYVCEVCNAGFVSRMILHNHTRGHKTGVFTCEICLKVYSTRRKLTYHKNLVHRHSYLVSKCGYCHQKFKSYHRKLEHLTKVHNVKPMTYTCKACNRNFNSQAALRVHRKRDHLMERKYKCTECDMEFFARAELNAHSLKHTGLREFQCDVCQKMFKRKFTLTEHMRIHENNCRFKCELCGAAFVQKCSWRGHMRNKHGIIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00971568;
90% Identity: iTF_00971568;
80% Identity: -