Basic Information

Insect: Megastigmus dorsalis
Gene Symbol: Hr39
Assembly: GCA_900490025.1
Location: UELU01142721.1:37918-41556[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.63 9.8e+03 -3.6 0.4 76 89 156 169 110 197 0.40

2 4 0.09 1.4e+03 -0.9 16.9 48 165 220 331 201 381 0.49

3 4 2e-08 0.00032 21.0 0.3 1 24 516 539 516 590 0.76

4 4 1.7e-69 2.7e-65 222.2 1.2 166 408 582 818 557 818 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.63	9.8e+03	-3.6	0.4	76	89	156	169	110	197	0.40
2	4	0.09	1.4e+03	-0.9	16.9	48	165	220	331	201	381	0.49
3	4	2e-08	0.00032	21.0	0.3	1	24	516	539	516	590	0.76
4	4	1.7e-69	2.7e-65	222.2	1.2	166	408	582	818	557	818	0.87

Sequence Information

Coding Sequence: ATGCACATTTGCAAAAGCGTGTGCAAGTACCTGGGCGGTCAGAACGGCGTGACGGTGTCGGTGGTGTCGAGCTGCGGCGGCCCCGGCAGCACCGCCAGCCccaccagcaacagcagcaccagcagcatcGGCAACCTCGTGACGAGCTCGGCCGCGGACTCGGCCGGCTCGACCGACTCGGCCAACAACATCGGCCACCTGCACCATGGCTCGATCGGCGACGAGGTCGACGCCGACAGCGACGGCGAGGTCAGCAGGATCGACTTCCGGGGCGTGAACCTCCGCACCAAGAAGAAGAGGGAGACCCTGGGAGCCGGGGGCAGCCTCCACGAGGCCGCGAGCGCCgctgccgcagccgccgccgccgcagccgccgccgacAACAGCTGCGGCGCCGAGGCCCTGCACCAGCAGCCCGAGAGGCCCATGTCCTGGGAGGGCGAGCTCTCCGACCAGGAAATGTCTTCCAACACCATCACCAGCCAGGACCACGAGGAGACGTCGATGGAGGGTGTGCAGGTGTGCAGCTCGAGTCCCGGGCCCCAGGAGCACAAGTTCCCGATCAAGCCGGAGCCGGACTTCCGCTCGAGTCCCGGCTTGCAGTCCCTCAGCGGCAACTCCCTCAACGAGACGATCGTCGCCGTCTCCCACGTCCAGCAGCtccaccaccagcaccaccagcacgCCCaccagccgcagcagcagcaacagcagtccCACCAGCAGTCCCACCAGCAGtcccaccagcagcagcagcagcagcagcagcaaaacgTCGAGCAGAACCAGCAGAGCGACCTGCCCCTACTGGTCGGCAAGCTCCTCGGCGGCTGCAACAGCTCCACACCGAACCACAGTCCCGTACTCATTCCTCGGCATCATCTCACCAAGCACAGCCACACCAGATCTCAAGTCCCGTCGCCCGACTCGGCGATCCACTCGGCCTACAGCGTCTTCAGCTCGCCGACCCAGTCGCCCCACGCGGGCCGTCACTCGGCCCTCGGTCCCGGCTCTCCCGTTCCCTCCTCCTCCCTGTCGCTCTCGCGGCACAGCTTCAACAACTCCAcctcctccctctccctctccctctcgcactCCCTCTCGCGCAACAACTCCGACGCCTCGAGCAGCTGCTACAGCTACGGCTCCCTCAGTCCGCCGACCCACTCGCCGCCGGCCGCTCTACAGGGACACCATTACGGCTCGACGCAGGCCGGAGTTGTGCAGGCTGCCGGGGACGCGGGCGAGCCCACGGCGCACCTCGACGATCAGGACGACTGCAGGATACCGTCCGCGCCCTCCGGGATCTCGACCCGCCAGCAGCTCATCAACAGTCCCTGTCCCATTTGCGGCGATAAGATCAGCGGCTTTCATTACGGCATATTCTCCTGCGAGTCCTGCAAGGGCTTCTTCAAGAGGACGGTGCAGAATCGCAAGAACTACGTGTGCCTTAGGGGGGCGGGCTGTCCGGTGACGGTGGCCACGCGGAAAAAGTGTCCGGCCTGCCGGTTCGACAAGTGCCTCAACATGGGCATGAAACTCGAGGCGATCCGGGAGGACCGTACGCGGGGCGGACGCAGCACCTACCAGTGCACCTACACCCTGCCGGCGAATCTGATGGGGGGCTCGGCCACCGGTGGCATGACGCCCGACAAAATGGCCCAGGGTGGGCCCTGCAGTCCCGCCCCACCCGGCAGCGAGCATCATCACTCGATGAAGCATCATTCCAATCATTCCCACAAGATGCAGGCGGTGCCGCAGCTCCTCCAGGACATCATGGACGTCGAGCATCTCTGGCATTACAACGACAACGACAGGGTCAGCACCGGTCAGGCCATGGGCTCGCTCCATCTCGCGCAGCATCCAGATTTTCTCTCCAATTTGTGCAATATAGCCGACCACAGACTCTACAAAATCGTCAAGTGGTGCAAGAGTTTGCCTCTCTTTAAGAATATATCGATCGACGATCAAATATGTTTACTCATCAATTCCTGGTGCGAGCTGTTGCTCTTCTCCTGCTGTTTTCGCAGTATGAGTACTCCAGGCGAGATAAGGGTGTCGCTCGGCAAATCCATCACTCTCGAACAAGCTAGACAATTGGGATTGGCCACCTGCATCGAGAGAATGCTCGCTTTCACGAATAATCTCAGGCGGCTCAGGGTTGATCAATATGAATATGTAGCTATGAAGGTGATCGTGTTGTTGACGTCGGATACGAGTGAGTTGAAGGAGCCAGAGAAAGTTCGCGCTTCGCAAGAAAAAGCCTTACAGGCACTGCAGCAGTACACGATTGCAAGGTATCCGGAAATGCCGGCCAAGTTTGGTGAGCTACTGCTTCGGATTCCGGATCTCCAACGTACTTGCCAAGCTGGCAAAGAACTACTGAGCGCCAAACGCGCCGAAGGCGAGGGCTGCTCCTTTAATCTGCTCATGGAGCTACTCCGCGGGGACCATTGA
Protein Sequence: MHICKSVCKYLGGQNGVTVSVVSSCGGPGSTASPTSNSSTSSIGNLVTSSAADSAGSTDSANNIGHLHHGSIGDEVDADSDGEVSRIDFRGVNLRTKKKRETLGAGGSLHEAASAAAAAAAAAAAADNSCGAEALHQQPERPMSWEGELSDQEMSSNTITSQDHEETSMEGVQVCSSSPGPQEHKFPIKPEPDFRSSPGLQSLSGNSLNETIVAVSHVQQLHHQHHQHAHQPQQQQQQSHQQSHQQSHQQQQQQQQQNVEQNQQSDLPLLVGKLLGGCNSSTPNHSPVLIPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHAGRHSALGPGSPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPPAALQGHHYGSTQAGVVQAAGDAGEPTAHLDDQDDCRIPSAPSGISTRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVATRKKCPACRFDKCLNMGMKLEAIREDRTRGGRSTYQCTYTLPANLMGGSATGGMTPDKMAQGGPCSPAPPGSEHHHSMKHHSNHSHKMQAVPQLLQDIMDVEHLWHYNDNDRVSTGQAMGSLHLAQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGCSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00969694;
90% Identity: iTF_00968903;
80% Identity: iTF_00968903;