Basic Information

Insect: Megamerina dolium
Gene Symbol: -
Assembly: GCA_963854835.1
Location: OY978526.1:79798994-79820829[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.0014 0.13 13.6 2.1 1 23 409 431 409 431 0.98

2 27 1.3e-05 0.0012 20.1 3.0 1 23 437 459 437 459 0.98

3 27 6 5.7e+02 2.2 1.9 2 23 506 527 505 527 0.93

4 27 0.0013 0.13 13.7 1.2 1 23 605 628 605 628 0.96

5 27 2e-05 0.0019 19.4 0.6 2 23 707 728 707 728 0.97

6 27 0.015 1.5 10.3 3.5 1 23 735 758 735 758 0.95

7 27 0.0027 0.26 12.7 1.0 2 23 767 788 766 788 0.96

8 27 0.0065 0.63 11.5 1.6 1 23 881 904 881 904 0.98

9 27 0.0055 0.52 11.8 1.6 1 21 912 932 912 933 0.94

10 27 0.97 93 4.7 2.3 1 19 942 960 942 965 0.89

11 27 0.00014 0.013 16.8 0.2 2 23 981 1002 980 1002 0.97

12 27 0.0001 0.0096 17.2 3.1 1 23 1009 1031 1009 1031 0.98

13 27 8.8 8.4e+02 1.7 1.7 13 23 1080 1090 1069 1090 0.85

14 27 0.00092 0.088 14.2 2.1 1 23 1174 1197 1174 1197 0.96

15 27 0.054 5.2 8.6 0.9 1 19 1204 1222 1204 1222 0.97

16 27 0.24 23 6.6 2.6 1 23 1234 1257 1234 1257 0.97

17 27 6.2e-05 0.006 17.9 0.6 1 23 1271 1293 1271 1293 0.97

18 27 0.00037 0.035 15.4 4.8 1 23 1300 1322 1300 1322 0.99

19 27 0.042 4.1 9.0 0.0 2 20 1349 1367 1348 1369 0.94

20 27 0.0056 0.54 11.7 2.8 1 23 1421 1444 1421 1444 0.96

21 27 0.11 10 7.7 0.5 1 23 1481 1504 1481 1504 0.96

22 27 6.3e-05 0.0061 17.8 2.7 1 23 1545 1568 1545 1568 0.98

23 27 2.3e-05 0.0022 19.2 0.2 2 23 1606 1627 1605 1627 0.95

24 27 0.0029 0.28 12.6 3.3 1 23 1633 1655 1633 1655 0.99

25 27 5.6e-07 5.3e-05 24.3 2.5 1 23 1661 1683 1661 1683 0.98

26 27 3.3e-07 3.2e-05 25.0 2.4 1 23 1689 1711 1689 1711 0.99

27 27 0.0022 0.21 13.0 0.1 1 22 1717 1738 1717 1741 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.0014	0.13	13.6	2.1	1	23	409	431	409	431	0.98
2	27	1.3e-05	0.0012	20.1	3.0	1	23	437	459	437	459	0.98
3	27	6	5.7e+02	2.2	1.9	2	23	506	527	505	527	0.93
4	27	0.0013	0.13	13.7	1.2	1	23	605	628	605	628	0.96
5	27	2e-05	0.0019	19.4	0.6	2	23	707	728	707	728	0.97
6	27	0.015	1.5	10.3	3.5	1	23	735	758	735	758	0.95
7	27	0.0027	0.26	12.7	1.0	2	23	767	788	766	788	0.96
8	27	0.0065	0.63	11.5	1.6	1	23	881	904	881	904	0.98
9	27	0.0055	0.52	11.8	1.6	1	21	912	932	912	933	0.94
10	27	0.97	93	4.7	2.3	1	19	942	960	942	965	0.89
11	27	0.00014	0.013	16.8	0.2	2	23	981	1002	980	1002	0.97
12	27	0.0001	0.0096	17.2	3.1	1	23	1009	1031	1009	1031	0.98
13	27	8.8	8.4e+02	1.7	1.7	13	23	1080	1090	1069	1090	0.85
14	27	0.00092	0.088	14.2	2.1	1	23	1174	1197	1174	1197	0.96
15	27	0.054	5.2	8.6	0.9	1	19	1204	1222	1204	1222	0.97
16	27	0.24	23	6.6	2.6	1	23	1234	1257	1234	1257	0.97
17	27	6.2e-05	0.006	17.9	0.6	1	23	1271	1293	1271	1293	0.97
18	27	0.00037	0.035	15.4	4.8	1	23	1300	1322	1300	1322	0.99
19	27	0.042	4.1	9.0	0.0	2	20	1349	1367	1348	1369	0.94
20	27	0.0056	0.54	11.7	2.8	1	23	1421	1444	1421	1444	0.96
21	27	0.11	10	7.7	0.5	1	23	1481	1504	1481	1504	0.96
22	27	6.3e-05	0.0061	17.8	2.7	1	23	1545	1568	1545	1568	0.98
23	27	2.3e-05	0.0022	19.2	0.2	2	23	1606	1627	1605	1627	0.95
24	27	0.0029	0.28	12.6	3.3	1	23	1633	1655	1633	1655	0.99
25	27	5.6e-07	5.3e-05	24.3	2.5	1	23	1661	1683	1661	1683	0.98
26	27	3.3e-07	3.2e-05	25.0	2.4	1	23	1689	1711	1689	1711	0.99
27	27	0.0022	0.21	13.0	0.1	1	22	1717	1738	1717	1741	0.90

Sequence Information

Coding Sequence: ATGAGCACTAACGATAGAATGCGTTGCCGTACATGTTTTGAGACATGTCAAAATGTCTTCTCCCTGCAGGAGCAGGCCCTTCCAAACACCACAAAGAAATCATTGGCTGATATAATAATGGAAATCGCAAAAAttgatACAACTGAACATGCTGATGTGCTGCCGAAATATATATGCGTAAAATGTTCACGTTTACTAAAATCTACATATCTATTTGTATTGCATGCGCGACATGTAAACGATCGTCTATTAGCTAGCATTGGAactgttgctgctactgttgcaGCTACAGAAAATGCTGATGCTGGTGAAAAGCAAGTGGATTGTTTGGTGGAAGCACCAATTGATATACCAGATGGCACATTGCAAATTAAGATGGAATCTGTATATGCAGAGGATGAAACAAACTTGACGGATGCCAATGTTGATGGGAATGTTGATGGTCCCTGTGATGGTTATGATTCTACTGCGAAAATGGTACCAGACATAAAAATggaacatttttataataacgATAATGTTGCAGAGCCATCAACCAGTTCAAATATGgCTAAGCTGAAAGATCCCTTTGTAATGATAGAACCAAATTGGCAAATGCACCATGAAGATGATATGGATTTTGCTAATGATAGTGATTACCATCCAACAGATAATAGCAATAAATTTACAACatccacaacaataacaacgaatgAAATGAGTGGTGTTGGTGGTCATTCGGGCAGTGATTTCCACTTTCGGCAAATTTATGAAGAACAGCAAAAAGATATTATGAAAAAGCTGAACGATATTATGAGGGAAGTGACTGTTGTCAATAAGAATCTGAATTCGGTCATTGATATTAAACGGAAAAGTCATAAAGAAGCTGAGAAATTtccattgaaaaatgaatttgattTGCAACAATTCGAGGAGAATTTAAATGATAGCAATACAGAACAATATATATACGTTTTAAAGAAATTCGTAGATAATGGCATTCTACATAAAACCCTATCACGTGTACTTTCCGATGAGTTTGTGCTCAAGTTTAATGTAGATGGTACTAAAAATAAGCTCGCTTTAAATTCATTTCCAAAATTTCTCAATGTTCTATTTAGTAACTCAGCCGAGGAAAACACAGAAGAGAAAGACACCACAACGAAACGAATTTGTCGTCGCAACAAACGTCGAGGACGACCACCCACAACGAATAAAAATGGTTCGACTAGGGGTGCGGGTCGTTTTACATGTGATGTTTGTAATAAGACATTTGCATGGAAAAAGGATCTTCATCGTCATGCGAATAGTCACTTTGCAACGCCTCAACATCAATGTGACTTTTGTGGGCGGCAATTTATACGTAAGGATAAACTTAAGGATCACATGAAAATACATCGAAAACAtcaagaagaacaacaaaaatcatcaaGTAGaagcaatgatgatgataattctGCACCATCATTTGTTGTACGTCATTCTGAATGGAATTTCGGTGAACGTCTCTATACACCAACACGTTTTCAGCGTGTAGAATGTAAATTATGTAGTATTGATTTTCAATCGATACACGAATTATGCGAACATTTTGTGAGTCATAGTGATAGACAAACATTGGAAATATTCCTAAAGGACAATAATCTGATGAAGGAACTATTTCCACATACAGAAAATATCGAAGAAATTCAAACAGCCATATGTGGGGATATCGAACAAAAGCGTTTTACCAAATACTATGCTATTGTGAATGAGTTTGGTTATGAAATGAGCCTCAGTGATTCCGATGCCACGATAGATGCTGATGCAGCTGAGTCGCAACAGCCAATTGAATATAAATGTGAATTGTGCGATGCAAAATTCGGCCGTAAATATAAGATGTTTAAGCATGTTCGCGCAGACCACGCCAATGATAAATTGCCACACAAATGCAATGTTTGCAAGTTGGAATTTGTTTGTACACAAATATTTGATCAGCATATGCGCACACAATGTCGCAGCAAGGTGAAGAAATATCAATGTGTCAAGTGTCCGGGCAAATTTATGTGGCGAGAAAATCTCGAAGGTCACAAATGTTCGAATCGATTCAATACGTCCGAGTATAGGGCAGCACAATTGTCGCGCACTTCTAATGTGCGACAATGTCCGATCTGCAACAAAACATTTGCGAAGATGAAAGCTCTACAGCGGCACATGGATCAACATGATGCTGATGGTAGTTCACATGAATGCCCAATTTGCCATCAACGTTTTCTTAAGGCGGACAATTTACGCCAACACTTCCGAGAAAGACATGAAGTTGAGTTGCAACGTCGCATAGTATGTTGTCTGTGCGGTGAACGATTTGAAAAGCTCTCAATGTTGCGTTCACACCTCCAAGAGCATGCTGATGGCCGTACCGGTATTAATATGCAAGAagggaaatttttcaaaaagcaCCTTCCAAACGGTTGCACCGAACGTCTTGCTGATTCGGTTGCCGCATCCATTGTGGCagactttaaaattgaaaatatgtcaCGCTACTACTTGGCAATTGATGAGAGTGGCAACGAGTTGGATCTGTACGATTCTGAAACAGACACGGAAACAAAGACGGCGTCTGACGAAACTGGGACGGACCCCACCGACAGCACGACTACGTCACAAACACCACCAACGTACAAATGTGAATTATGCGCTCAGGTATTCAATCGACGCAAGCATATTCTTTTGCATCAGAGCACCGCACATGCCGATGCAAAAAATTGGCCACACACCTGCACACAGTGTCACAAGCCATTCGTCAGTATGGAACTATTGCAATATCATCTGAATAGAGATTGTCTCAATTTACTCAAGAATTATCAGTGTAAAAAGTGTTCGGCCCGTTTTGTATGGGAAGATAATCTGCAGGTGCATTGCAAACTGAAACACCTAGATTCCGAACAGGAAATCAGTCGACAGCTGGCAAATAAACTGCAGTGTGAGGTATGCGATAAGGTATTTGTATGGGCCAAAGACTTGACCCGACATCGACGTATCCATATGCCAGACGATGAGAAATACGACTGCCCGTTTTGTGAACGCAAATTCAATCGCAAAGACAATATGCATTCACACTTGCGCGTACATGGTGCGGCCGCATATGAGACCATTTGCAAGAAGGAGCTGGTGCGCAATAAACCGCTCAAAAAGAAGAGTATCGATCAGAATTTGTGCAAGCGCAATGGTTGCAAGCATATACAGTGTATGATTTGTATGTCGAAACATTCGAAAATATCCGATTTGCGCACGCATTTGCGCACCCACCAATATATCGTGTCGTTCGAGCAGCGCAACGAATCGATTGCAGATATCTCGATGCTACTTTATCCAGACGAACCGCCAAAGTCGCAGGAAACGCTCATTGAGCATATCATAGCAGATATCGCAGCACAACAATATGATCGCTTCTATTCCATAACAAATGAGGTTGGCTATGAGCTTAGCATAAATAGTTCCGAAACGGAAAGTGATTCGGATTCGGAAAATGCCGTCGACTCTAGCCCACGGAAATTGTACACTTGCGATTTGTGTACCAAAACATTTTATCGTAAATATCAAGTGTACGAGCATCAAATGTGGAACCATGAATGGTTGGAGGCTCCGCATGTCTGTCATCATTGTCAGGGACGTTTTGTGTCGGCGGAATTGTTACAGGCCCACTGTGCCCAACAGTGTACCAATGAACAGAAACGTTTCGTGTGTCGTAAGTGCTCACATCGATTTATGTGGaaacaaaatctaaaggcgCATGTACTTACAATGCATGCGGAAACTGAGGATGGCAAGAAAAAGGCATCGCGAACATACGATTGTCTTGAATGTAATCGTAGTTTTCAAATGCAGAAAGATCTAACACGTCACATGATTGTGCATCAGAGCGATGTGTCTGTGTTCAAATGTCTGTGGTGCCAACGCAAATTTTATCGTCAAGAGAATTTGCATATGCACATAAAACGTCATGGTATCACACCAGAAACTTTGGCTACTGCAGAATGTTGGTTGACCGCTACAAATAGTCCCAACGGTGAGAAAATCATCCAGTGTAAGGTGTGCAATGTGCAATTCATGAATATTGCTGAGTTGCGACGACATCTAATATATGAGACATCATCGTCAACCACCCATCACGCATATAGCTCACAATTGAACTATTCCATTACCAATAAGCTGGGCTTTGAGTTGGAACTTGATGATTCAGAAACGGATGGTGAGAGTGAGGCAGCTGAGGATGGTGGTGTCAACACAAAGCCATCATATTATTGTGAAACTTGTAAACTGGTATGTAAGCGAAAGTATGAAATGGCACAACATCAGCGTGCAATGCATAAGCCAGAACAGCTGCCATTAAAATGTGAGCGGTGCATTTTTAAAACTGTTTCCAAGGAAATTCTAACGCGCCATATGCGTACGCAATGCTTTAATAcggaaaaacaatttcaatgtgACGAATGTAGTATAAAATTTATGTGGCAGGAGAATCTTGATAATCACAAACGTTTACTGCATAGcaatggtggcggtggtggtgctgcagctgctactgctgttggtGTACCAATACCTGAAGCTTCTAACCCTGAATTGTTATTCACGACCTGTATTCAACAATCACCTGTTAAAAAGATATTCCAATGTGATAAATGCAAccgtaaatataatcgtaaagATCGTCTGACGGCacacattaaaaaaatgcaCATAGAGCCGCCGAAGGTGCCACCGAACGAGCAATGCAATGACGGTTATTTAGATGCAGCGACCGGGGAGAAATCGGTAGCTAAACCAAAGTCGACAGCAGATAAAAAATTCCTTTGTGCATTCTGCGGTCGGGCCGTATCCTCGTCATCCAATCTGATCATTCATATGCGGCGTCATACTGGCGAGAAACCatttaaatgtgatttttgCGATATGGCTTTTCCACGTTCGTCTGATATGCAGTGTCATCGTCGTACACATACCGGTGAGAAGCCGCATAAATGTACTGTTTGCGATAAGGCATTTGCGCGTTCGTATAAATTACAGACCCATATGCGTATACATTCGGGTGAACGACCCTACAAATGCACTTATTGTGAGAAGAGTTTTACACAATCTAATGATTTAACATTGCACATACGGCGACACACCGGAGAACGCCCATATGTTTGCGGTATATGTGGAGAGCGCTTCATACAAGGAACTGCCCTTAAAAACCATCGTACAATGCGTGGCCATTATGAAGATATTGGACCTAAACGAACGATTCTGGAGcagttttaa
Protein Sequence: MSTNDRMRCRTCFETCQNVFSLQEQALPNTTKKSLADIIMEIAKIDTTEHADVLPKYICVKCSRLLKSTYLFVLHARHVNDRLLASIGTVAATVAATENADAGEKQVDCLVEAPIDIPDGTLQIKMESVYAEDETNLTDANVDGNVDGPCDGYDSTAKMVPDIKMEHFYNNDNVAEPSTSSNMAKLKDPFVMIEPNWQMHHEDDMDFANDSDYHPTDNSNKFTTSTTITTNEMSGVGGHSGSDFHFRQIYEEQQKDIMKKLNDIMREVTVVNKNLNSVIDIKRKSHKEAEKFPLKNEFDLQQFEENLNDSNTEQYIYVLKKFVDNGILHKTLSRVLSDEFVLKFNVDGTKNKLALNSFPKFLNVLFSNSAEENTEEKDTTTKRICRRNKRRGRPPTTNKNGSTRGAGRFTCDVCNKTFAWKKDLHRHANSHFATPQHQCDFCGRQFIRKDKLKDHMKIHRKHQEEQQKSSSRSNDDDNSAPSFVVRHSEWNFGERLYTPTRFQRVECKLCSIDFQSIHELCEHFVSHSDRQTLEIFLKDNNLMKELFPHTENIEEIQTAICGDIEQKRFTKYYAIVNEFGYEMSLSDSDATIDADAAESQQPIEYKCELCDAKFGRKYKMFKHVRADHANDKLPHKCNVCKLEFVCTQIFDQHMRTQCRSKVKKYQCVKCPGKFMWRENLEGHKCSNRFNTSEYRAAQLSRTSNVRQCPICNKTFAKMKALQRHMDQHDADGSSHECPICHQRFLKADNLRQHFRERHEVELQRRIVCCLCGERFEKLSMLRSHLQEHADGRTGINMQEGKFFKKHLPNGCTERLADSVAASIVADFKIENMSRYYLAIDESGNELDLYDSETDTETKTASDETGTDPTDSTTTSQTPPTYKCELCAQVFNRRKHILLHQSTAHADAKNWPHTCTQCHKPFVSMELLQYHLNRDCLNLLKNYQCKKCSARFVWEDNLQVHCKLKHLDSEQEISRQLANKLQCEVCDKVFVWAKDLTRHRRIHMPDDEKYDCPFCERKFNRKDNMHSHLRVHGAAAYETICKKELVRNKPLKKKSIDQNLCKRNGCKHIQCMICMSKHSKISDLRTHLRTHQYIVSFEQRNESIADISMLLYPDEPPKSQETLIEHIIADIAAQQYDRFYSITNEVGYELSINSSETESDSDSENAVDSSPRKLYTCDLCTKTFYRKYQVYEHQMWNHEWLEAPHVCHHCQGRFVSAELLQAHCAQQCTNEQKRFVCRKCSHRFMWKQNLKAHVLTMHAETEDGKKKASRTYDCLECNRSFQMQKDLTRHMIVHQSDVSVFKCLWCQRKFYRQENLHMHIKRHGITPETLATAECWLTATNSPNGEKIIQCKVCNVQFMNIAELRRHLIYETSSSTTHHAYSSQLNYSITNKLGFELELDDSETDGESEAAEDGGVNTKPSYYCETCKLVCKRKYEMAQHQRAMHKPEQLPLKCERCIFKTVSKEILTRHMRTQCFNTEKQFQCDECSIKFMWQENLDNHKRLLHSNGGGGGAAAATAVGVPIPEASNPELLFTTCIQQSPVKKIFQCDKCNRKYNRKDRLTAHIKKMHIEPPKVPPNEQCNDGYLDAATGEKSVAKPKSTADKKFLCAFCGRAVSSSSNLIIHMRRHTGEKPFKCDFCDMAFPRSSDMQCHRRTHTGEKPHKCTVCDKAFARSYKLQTHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYVCGICGERFIQGTALKNHRTMRGHYEDIGPKRTILEQF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00967387;
90% Identity: -
80% Identity: -