Mgen001303.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megalopta genalis
Gene Symbol
-
Assembly
GCA_011865705.1
Location
NW:831619-836224[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 8.5 4.5e+02 0.7 2.2 1 21 222 242 222 244 0.69
2 16 0.052 2.8 7.7 1.6 1 23 252 275 252 275 0.91
3 16 0.0003 0.016 14.8 0.8 1 23 281 305 281 305 0.92
4 16 7.6 4.1e+02 0.9 0.1 3 9 341 347 339 351 0.83
5 16 0.062 3.3 7.5 5.0 1 23 387 409 387 409 0.93
6 16 0.0018 0.098 12.3 0.5 1 23 416 439 416 439 0.92
7 16 0.0009 0.048 13.2 5.6 1 23 445 467 445 467 0.97
8 16 0.00012 0.0066 16.0 2.4 1 23 473 495 473 495 0.99
9 16 3.2e-06 0.00017 21.0 2.2 1 23 501 523 501 523 0.98
10 16 0.00039 0.021 14.4 0.2 1 23 536 559 536 559 0.95
11 16 6.6e-05 0.0035 16.8 3.7 1 23 575 598 575 598 0.96
12 16 0.00011 0.0056 16.2 1.1 1 23 606 629 606 629 0.98
13 16 0.00042 0.022 14.3 0.7 1 23 635 657 635 657 0.97
14 16 0.00059 0.032 13.8 5.5 1 23 663 685 663 685 0.98
15 16 2.7e-06 0.00014 21.2 1.5 1 23 691 714 691 714 0.98
16 16 0.0015 0.078 12.6 1.6 2 23 719 740 719 740 0.97

Sequence Information

Coding Sequence
ATGACAGACTTTTCAAAGATTCATAATGATGCTGTATATACATGTCCTAATTGTAAAATTGGTTTAATGATTCTATTAGTCAGTAATTCTCAAGGCTGTGATTATACCTTTCAAATCGCATTAGCTATGGTAAATCATTCAGaaaagaaacatattttaaaagagaaaaatatacaaatacataaaaatttaatacatttcaataatattaagaataacaATGTACATCTTAAAGATGTAAGTAAAATGACAGACATAGAAGACATTGAAAATTCGCATGATCAAGTGAGTTTTACATTACCAGTGTTACAACAAGAAGATGCAAATTGTTTTGATAAACCATCCGTTAAAGAAGATTCAGAAATAATGAcacagaaaagaagaaaaagaaaactcgttaaaactgaattttatgAAGATTCAAGTAGTCTTACAAAAGTactaaaattgaagaaaatgtaCGAatctaatgaaaatttattggtCTATAACAATGACTCCGTGAACACTTTAATAAAGATTGAACCAGAAAGTGACAATGTTTGTGAAGCAGACAGCGAAACTGAtattaaaagtaacaaaaattcacACGTGAATCAATTATACACACTTGAAAAGGATCAGACTCAAgaagaaaatgatatttataaatctTGCTTGAAATATGTCTGTAAATTTTGTGGAGTACGTTATCTTTCCCACATGAAATATGAATTTCATATGGAGAGGCACAAATTAGATAAAATGTacaagtacatatgtacattatgTAGTAAAGAAACAAGCAATGAAAACTTACTGTGGGATCATTACTTTCACACTCATAAAAGTTTACAACGTTACATATGTACAGAATGTGGGAAATTATTTGCGAAAAGGTCCAGATTAAATGGTCAtcaaaaaatgtacaatcaTAAAGGTGTGAAACAGATCCAAGTTAATTCTAGCGATGATAATATTAACAATGATATCATACAAAAAGCTATAGCTGAAACTGAACAGAGGAAACATTCTGTAAACTGTAATCTCTGTGGAAAAATAATTTCCGATTTCAATGCCGATGCTATTAATGATCTAGTTACATGTGCCGACTGTGAAGACTCTACTCTTTCTCTTATGGTAGATGGCAATGAAACAAAAGTAATCTCTCCTCGACAATATCACTGCACTCAGTGCCCAAAACACTTTGTACGAAAAGAAAGACTGGAGTTTCATGAAATGAGGCACAATGAAAACATGAACGAATTCGTTTGCAGTACTTGTGGAAAAGAATTTAGAGCAGAGAATTCATTATACGAGCATTACCTTTTCGTTCACAAAGGCGCGAGGCCTCATATTTGCGAACACTGCGGTAAATCGTTCCAATTAAAAGCTAGGTTGAAAGAACATCATCGAATTCATACAGGTGAAAGACCCTATCAATGTGATGTTTGCGGTCAAAAATGTAGAACCACAAACGCGTTGAAGCTACATCGGAAGATTCATTTTTCCAATAATAGATATACTTGCAATGTGTGTAATAAGTCATTCAGTAAAAAACAGAATATGAACGAGCACTTAGAAAAGCATTggaaaaacgataaaaacgtGACATTACCAGAAGTATTTAGATGTCCAATTTGTTTAGAAAACTTCCCAACATATCGTATGTTGAAGTATCATATGATCGAAATtcataaattgaataatcagGATCCAATTCTTACAAAACAAAAGCCGTGGTACGAATGCGAAGAATGTCACGAAAAATTCAAACATCAAATGTCTTTAAAAGCTCATAAAGAGAGGGTACACGAAGGGAGAGTAGACCCACTCTATCAATGTGATACATGTAACACTACTTACAGAGTTAAGCAACTTCTAGTGAATCATATCAACAGTAAACACAACGGCGAAAGGCGCTACAAGTGCGCACAATGTGAAAAGGGATTCAATGATACAAAATCCTTGTATAATCATGTGCTGTTGCATACTGGGAAAAAACCGTATGTTTGCGAATATTGTAACATGCGTTTCAGAAGAAAAGATTCCAGAGATCATCACCGTAGAAAACACACAGGTGAACAACCTTATCAGTGTCCAGATTGTGGAGAATCATTTTCTACATATAATAATCGGTCCAAGCATCGGAAACGGGAACACGGGGAAGATCCTGAATGTCCTGAGTGTAAGGAGAAATGCAGCAGCCAACAGGAAGTTAGAATCCATTTGAATAAACATCTTggagaaaaattgaaggaaCTACAAAGTATAAATAGTGAAGAGGCATAG
Protein Sequence
MTDFSKIHNDAVYTCPNCKIGLMILLVSNSQGCDYTFQIALAMVNHSEKKHILKEKNIQIHKNLIHFNNIKNNNVHLKDVSKMTDIEDIENSHDQVSFTLPVLQQEDANCFDKPSVKEDSEIMTQKRRKRKLVKTEFYEDSSSLTKVLKLKKMYESNENLLVYNNDSVNTLIKIEPESDNVCEADSETDIKSNKNSHVNQLYTLEKDQTQEENDIYKSCLKYVCKFCGVRYLSHMKYEFHMERHKLDKMYKYICTLCSKETSNENLLWDHYFHTHKSLQRYICTECGKLFAKRSRLNGHQKMYNHKGVKQIQVNSSDDNINNDIIQKAIAETEQRKHSVNCNLCGKIISDFNADAINDLVTCADCEDSTLSLMVDGNETKVISPRQYHCTQCPKHFVRKERLEFHEMRHNENMNEFVCSTCGKEFRAENSLYEHYLFVHKGARPHICEHCGKSFQLKARLKEHHRIHTGERPYQCDVCGQKCRTTNALKLHRKIHFSNNRYTCNVCNKSFSKKQNMNEHLEKHWKNDKNVTLPEVFRCPICLENFPTYRMLKYHMIEIHKLNNQDPILTKQKPWYECEECHEKFKHQMSLKAHKERVHEGRVDPLYQCDTCNTTYRVKQLLVNHINSKHNGERRYKCAQCEKGFNDTKSLYNHVLLHTGKKPYVCEYCNMRFRRKDSRDHHRRKHTGEQPYQCPDCGESFSTYNNRSKHRKREHGEDPECPECKEKCSSQQEVRIHLNKHLGEKLKELQSINSEEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00183460;
90% Identity
iTF_00183460;
80% Identity
-