Basic Information

Insect: Megalopta genalis
Gene Symbol: -
Assembly: GCA_011865705.1
Location: NW:216561-231394[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.9e-05 0.0021 17.5 1.4 1 23 449 471 449 471 0.96

2 18 0.0024 0.13 11.9 1.6 1 20 477 496 477 499 0.94

3 18 9.8e-06 0.00052 19.4 1.4 1 23 505 527 505 527 0.98

4 18 5.7e-05 0.003 17.0 4.4 1 21 533 553 533 555 0.95

5 18 7.7e-06 0.00041 19.8 5.6 1 23 561 583 561 583 0.99

6 18 1.8e-05 0.00094 18.6 5.3 1 23 589 611 589 611 0.97

7 18 6.6e-05 0.0035 16.8 6.9 1 23 617 639 617 639 0.96

8 18 6.5e-08 3.5e-06 26.3 2.7 1 23 645 667 645 667 0.98

9 18 4.8e-05 0.0026 17.3 6.7 1 23 673 695 673 695 0.97

10 18 1.5e-05 0.0008 18.9 5.8 1 23 701 723 701 723 0.98

11 18 4e-07 2.1e-05 23.8 2.9 1 23 729 751 729 751 0.98

12 18 5.9e-06 0.00031 20.1 7.8 1 23 757 779 757 779 0.98

13 18 1.9e-05 0.00099 18.6 9.1 1 23 785 807 785 807 0.98

14 18 2.4e-05 0.0013 18.2 7.5 1 23 813 835 813 835 0.98

15 18 0.0012 0.062 12.9 8.8 1 21 841 861 841 863 0.94

16 18 8.9e-06 0.00048 19.6 0.4 1 23 869 891 869 891 0.98

17 18 0.021 1.1 8.9 4.5 1 23 901 923 901 923 0.98

18 18 3.4e-07 1.8e-05 24.0 1.3 1 23 929 951 929 951 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.9e-05	0.0021	17.5	1.4	1	23	449	471	449	471	0.96
2	18	0.0024	0.13	11.9	1.6	1	20	477	496	477	499	0.94
3	18	9.8e-06	0.00052	19.4	1.4	1	23	505	527	505	527	0.98
4	18	5.7e-05	0.003	17.0	4.4	1	21	533	553	533	555	0.95
5	18	7.7e-06	0.00041	19.8	5.6	1	23	561	583	561	583	0.99
6	18	1.8e-05	0.00094	18.6	5.3	1	23	589	611	589	611	0.97
7	18	6.6e-05	0.0035	16.8	6.9	1	23	617	639	617	639	0.96
8	18	6.5e-08	3.5e-06	26.3	2.7	1	23	645	667	645	667	0.98
9	18	4.8e-05	0.0026	17.3	6.7	1	23	673	695	673	695	0.97
10	18	1.5e-05	0.0008	18.9	5.8	1	23	701	723	701	723	0.98
11	18	4e-07	2.1e-05	23.8	2.9	1	23	729	751	729	751	0.98
12	18	5.9e-06	0.00031	20.1	7.8	1	23	757	779	757	779	0.98
13	18	1.9e-05	0.00099	18.6	9.1	1	23	785	807	785	807	0.98
14	18	2.4e-05	0.0013	18.2	7.5	1	23	813	835	813	835	0.98
15	18	0.0012	0.062	12.9	8.8	1	21	841	861	841	863	0.94
16	18	8.9e-06	0.00048	19.6	0.4	1	23	869	891	869	891	0.98
17	18	0.021	1.1	8.9	4.5	1	23	901	923	901	923	0.98
18	18	3.4e-07	1.8e-05	24.0	1.3	1	23	929	951	929	951	0.97

Sequence Information

Coding Sequence: ATGAATAGTGAGCAGCATGCATTGCCAGCGACTACGCAGGCACAACAAGAgGATGTAAATGCGGGTCAAAGTGGTCGTCCTTCATATCCAGGTGGTTTGGCTACAGCAACTAGTCTTGGCAATGTTGGGAGTACCCCACATTCATCCGCAGACCTGCGTGTAGGTACAGCAGTAGCGTTAGCCTCCTCGGTAGCTAAATATTGGGTCCTCACGAATCTGTTTCCTGGACCGCTACCTCAGGTCTCAGTCTATCATCATTCCCACCACAACTCCTCACACAGGAGTAGTGGAGGTGGAGAGGCATCTTCCAAAGAGCCAGCCTCTTCATTGAACCAAGAAATGGCGTTAACTTCCAGCTCACACCATCAGTCAACACCTAcgcatcatcatcatcaacCTACAGTTAGCACTAGCAGTCATCATAGTTCTTTACAACCAAATCCTCAGcagATTCCAGTATCTCTGCCAGGCCTTAATTTAGACGGAGCGCATATACCTACCAGTGTCAGTCATTTACAGGCAGCACATGCACAAATGCAACAACAAATACAGgcacaacaacagcagcagctgcatcagcaacaacaacaacagccgcagcagcagcaacaacaacctCAACAGCAACCTCAACAACAACAATCTCATCATCAAATGCAAAGTCATCAAAATGCTCAGAATAATGGACCAACTGCACATAATCAAAACGCACAGAGAGATGATAATAAAGTGAAAGATGAAGGTGGAAGTTGCACAACTGAACGTTGTAGTGATAATCAAGTCCACTGTCAAGTTCAGTGTGACCTTCAGTTACAAACATCTCAAGATATACAACAAAGCCTtatgcaacaacaacagcagcagcaaatTGGGGTGAATATAAGTGGAAATTCTTCTACTGAAGGTGGTAACAATACTGAAAAGccagagaaagaaaaggagcTGCGTCAACTAAACATGACGCAATTCCAAGTACCAGATTTAAAACCAGGAGGTCATATGATGGATGTAAGAACAGCAGATGGTTCTGTTGTAAAAATTAGTGCTGGAAATGAACAAGATTTAGCAAAAACTCTTGGTGTTGAAATGGTGCAAAATATGTATAagGTTAATGTTGAAGATATTAATCAGCTTCTAGCATATCACGAAGTATTTGGAAAATTACAGAGTGAAATAGCAGCTGGTACCACCTTAGTTGGAAGTACAGTTCCTACACAAACAGTTACCACTATACAGAATGGAACACCAATTGTGCAACAAGTTCAATTAAATAAGTTTGATATCAAATCAAGTGACGGCGAAGCTACTCCAGGACCAAGTGCATCACCTGTGTCGGTTGGGAGTCATGCCTGTGAAATATGTGGAAAGATTTTTCAGTTCCGTTATCAACTTATCGTACATCGTCGTTATCATACGGAAAGAAAACCTTTCACTTGCCAgGTGTGTGGCAAAGCATTTTTAAACGCGAATGATTTGACTCGTCACGGTAAATGCCACTTAGGTGGATCTATGTTCACTTGTACAGTATGTTTTCACGTGTTTGCAAATGCGCCATCGTTGGAACGTCATATGAAACGTCACGCAACTGATAAACCATATAATTGTACTGTATGTGGAAAAAGCTTTGCAAGAAAAGAACATTTGGATAATCACACACGTTGTCACACTGGAGAAACACCTTACAGatgCCAATACTGTTCAAAAACATTTACTAGAAAAGAGCATATGGTAAATCACGTTCGTAAACATACGGGCGAAACTCCACATCGATGTGATATTTGCAAAAAGAGCTTTACTCGCAAGGAACACTTCAtgaatcatgtcatgtggcaTACGGGAGAAACTCCCCATCATTGCCAAGCCTGTGGCAAGAAGTACACACGTAAAGAACATCTTGCAAACCATATGCGCTCACACACCAATGATACACCGTTTCGTTGTGAAATATGCGGTAAGTCGTTCACGAGAAAGGAGCATTTTACGAACCACATAATGTGGCACACGGGTGAGACGCCGCACCGCTGCGATTTCTGCTCGAAGACGTTTACTCGAAAGGAGCATCTCCTGAACCACGTCCGCCAGCACACGGGTGAGTCTCCACACCGATGCGGCTTCTGCTCCAAATCGTTCACCAGAAAGGAACACCTTGTTAACCACATCCGCCAACACACAGGGGAGACGCCCTTCCGCTGTCAGTACTGTCCAAAAGCATTTACGCGAAAGGATCACCTGGTGAACCACGTCAGGCAGCACACGGGTGAGTCACCGCACAAGTGCCAGTATTGCACCAAATCCTTCACGAGGAAGGAACATTTGACAAATCACGTGCGTCAACATACAGGCGAATCGCCACACCGATGCCACTTCTGCTCCAAGTCATTTACTCGTAAGGAGCATTTAACGAATCATGTCCGTATTCACACTGGCGAATCACCGCATAGGTGTGAATTCTGTCAGAGGACATTCACTAGGAAAGAACACCTTAACAATCATCTCCGTCAACATACCGGAGATTCCTCACATTGTTGTAATGTGTGTTCGAAACCATTCACAAGAAAGGAACACCTTGTGAATCATATGCGATGTCATACTGGCGAACGTCCATTTGTATGTACTGAATGTGGCAAGAGTTTCCCGCTAAAGGGTAATCTGTTGTTTCACATGCGTTCGCATAATAAAGGAAGTAATGCTGAAAGACCGTTTCGTTGCGACCTGTGTCCTAAAGACTTCATGTGCAAGGGACATTTGGTGTCACACAGACGATCCCACTCGGACGAACGACCGCACAGTTGTCCAGATTGTGGAAAAACTTTCGTGGAGAAGGGCAATATGTTGAGACATTTAAGAAAACATGCAGCAGAAGGACCACCGACGCAAGTCAGTACACCGTCAGCCATTCCTCAATCTGGTGTTTTGCCAATCCCGACAGCAGCAGTTTTGGTTGGCCATCCGCTGGCACCGCCGGCACCACCTGTAGTGCCGCAACACACGGTCGTTGTACCCACTCCACCTGGTGTATTAACCTCTTACTAA
Protein Sequence: MNSEQHALPATTQAQQEDVNAGQSGRPSYPGGLATATSLGNVGSTPHSSADLRVGTAVALASSVAKYWVLTNLFPGPLPQVSVYHHSHHNSSHRSSGGGEASSKEPASSLNQEMALTSSSHHQSTPTHHHHQPTVSTSSHHSSLQPNPQQIPVSLPGLNLDGAHIPTSVSHLQAAHAQMQQQIQAQQQQQLHQQQQQQPQQQQQQPQQQPQQQQSHHQMQSHQNAQNNGPTAHNQNAQRDDNKVKDEGGSCTTERCSDNQVHCQVQCDLQLQTSQDIQQSLMQQQQQQQIGVNISGNSSTEGGNNTEKPEKEKELRQLNMTQFQVPDLKPGGHMMDVRTADGSVVKISAGNEQDLAKTLGVEMVQNMYKVNVEDINQLLAYHEVFGKLQSEIAAGTTLVGSTVPTQTVTTIQNGTPIVQQVQLNKFDIKSSDGEATPGPSASPVSVGSHACEICGKIFQFRYQLIVHRRYHTERKPFTCQVCGKAFLNANDLTRHGKCHLGGSMFTCTVCFHVFANAPSLERHMKRHATDKPYNCTVCGKSFARKEHLDNHTRCHTGETPYRCQYCSKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQACGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCGFCSKSFTRKEHLVNHIRQHTGETPFRCQYCPKAFTRKDHLVNHVRQHTGESPHKCQYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCQRTFTRKEHLNNHLRQHTGDSSHCCNVCSKPFTRKEHLVNHMRCHTGERPFVCTECGKSFPLKGNLLFHMRSHNKGSNAERPFRCDLCPKDFMCKGHLVSHRRSHSDERPHSCPDCGKTFVEKGNMLRHLRKHAAEGPPTQVSTPSAIPQSGVLPIPTAAVLVGHPLAPPAPPVVPQHTVVVPTPPGVLTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00899003;
90% Identity: iTF_00983718;
80% Identity: -