Basic Information

Insect: Megalocaria dilatata
Gene Symbol: ham
Assembly: GCA_034642435.1
Location: CM067859.1:34681586-34714204[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.13 14 7.5 0.3 2 23 76 98 75 98 0.92

2 9 0.00016 0.018 16.6 3.3 1 23 105 128 105 128 0.95

3 9 9.3e-09 1e-06 29.9 3.1 1 23 134 156 134 157 0.96

4 9 1.4e-06 0.00016 23.1 1.7 1 23 163 185 163 185 0.95

5 9 3.5e-05 0.004 18.7 5.0 1 23 191 213 191 213 0.99

6 9 0.013 1.5 10.6 0.7 2 21 221 240 220 241 0.91

7 9 1.2e-08 1.3e-06 29.6 0.7 1 23 565 587 565 587 0.98

8 9 1.5e-06 0.00017 23.0 1.6 1 23 593 616 593 616 0.97

9 9 1.2e-05 0.0014 20.1 3.4 1 23 622 644 622 644 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.13	14	7.5	0.3	2	23	76	98	75	98	0.92
2	9	0.00016	0.018	16.6	3.3	1	23	105	128	105	128	0.95
3	9	9.3e-09	1e-06	29.9	3.1	1	23	134	156	134	157	0.96
4	9	1.4e-06	0.00016	23.1	1.7	1	23	163	185	163	185	0.95
5	9	3.5e-05	0.004	18.7	5.0	1	23	191	213	191	213	0.99
6	9	0.013	1.5	10.6	0.7	2	21	221	240	220	241	0.91
7	9	1.2e-08	1.3e-06	29.6	0.7	1	23	565	587	565	587	0.98
8	9	1.5e-06	0.00017	23.0	1.6	1	23	593	616	593	616	0.97
9	9	1.2e-05	0.0014	20.1	3.4	1	23	622	644	622	644	0.99

Sequence Information

Coding Sequence: ATGAAAAGATATAGAGTCATAGAAGAAATAAAGTTATGGTACGAAACATGTGTGGACATTCCAAGCGGTTCCGAACTTGTTCTGGGACCCAGGGAACCACTCAATCTCCAGGATATGTTCGGAGATTCTACCTCAGCTGACGAAAAATCCGACAGAGAAACAGCTTCACAACATAGTGGAACTGTTGACGATAGAGAAGAAGACGAAGAAGATGAGTCTGAAATAAGGTGCTGTGTTTGTGAACAACCCTTTACGGATGTGGACAAgctCGATGAGCATCTAGTAATCAAACACAACTACCGAAAGGACGAATTTAAGTGCGAATATTGCCCTAAATCCTACAGTCACAGACCATGTCTGATCAAGCATAAAGCCGTCGTACATGGTGAACATCGAAAATATCATTGTGAAAATTGCCCTAAGGTTTTTACCGATCCCAGCAATTTGCAAAGGCATATAAGGACGCATCACGTAGGCGCTCGATCTCACGCCTGTCCTGAATGCGGAAAAACTTTCGCCACGTCTTCTGGATTGAAGCAACACACTCACATCCATTCCTCCGTAAAACCCTTCCAGTGCGAAGTCTGTTTTAAGGCCTACACACAATTCTCGAATCTGTGCCGCCACAAACGAATGCACGCCGATTGCCGCATGCAGATTAAGTGCATCAAGTGCGGACAATCTTTCTCCACGGTGACCTCGCTGTCAAAACACAAACGATTCTGTGATTCAAGCACCTCCGCATCAACCCTTGGAGCCCCGCCGCCCTTATCATTGAACTCGATGGCCAGCAACAACCCCTTCTCGCTGTACAGGCCGACCTGTCACATGCCTTTCTTCCCACCGCATTTCCCTTcatatcatcagatttttcaccCTTCCGGTCCCCCGTCGGGCTTCATCAACCCCCTTCTTTTCAATCAATTACCCAAGCTGAGAACGGAGGAATTACCTGAAATGCCTTCGCCGAAAAGAATGAGATCGTCAAGTACAGAAAGGATATCTCCGTGCGCAGAACGTGTTACTCCCCCAAGGGTTCCTTCAGTCAATCTGAAAGTTAGTCCTCCAACTGCTGAAGAAGCGCACTTAACTGCATCTCCAGCTAAACCGACCACGGTCCCAGTGAAAATGGAGAGAATTGAAATACGTCCAAGTACGCCAGAAAGCAACAACTATCCGACAGATCTGTCCAAAACTTCCGAAGAAAGGTCGCCAAAACATCCGAGTCCAACAACGAGCGAAGAAGGTGAACAACCCTTAGATCTCAGTATGACTTGGAAAAAGACCAAAGTCGAACTCGTAGAAAACTTATCTCCATCTCCAAGATCAGAGAGGGCTAGTGAAGTTTCTACGCCACCCAAACCAGTAGAAGAGAAAATAGATGTGATTACTGTCGAAGAGGAGAAAAGATCAATGGAAAAGATGCAGGTTACACCTCCAATGGCTTATCCTAGACCAATTCACCCAATGCTTCTGGACATGTACCGACCCAGTTTCGCGAATTTCACATCTCCATCTAGCAACGACAGATTACTCCCTTCACCCTTTGGACCTCATAGATTTCCATTCTTGAACAACCTTCAGCCACAGAGAAACTTCGATCTGCTTAGGCCAGGTCTGCAGAATTTTGGTGGTGTCAAGCCTTTCCATGACGTGATGCAACAGCAAACTCAAGGGAAGATCAAAGATAGATACGCTTGCAAATTTTGCGGGAAAGTTTTCCCAAGGTCAGCAAATTTAACGCGACATCTAAGAACACATACTGGAGAACAACCGTATAAATGTAGATACTGTGAAAGATCTTTCAGTATATCCAGCAATTTACAGAGGCACGTCAGAAATATTCACAATAAAGAGAAGCCATTCAAATGCCCCCTTTGCGAAAGATGCTTCGGTCAACAGACTAACCTAGATAGACATCTGAAAAAGCATGAATCTGATGATGGAAGTGGAGGTGTTGCTGTAGCTGACTCTCCGGGTAGCAGTAATGAAAACGAGAGAGAAGATGCCTACTTTGATGAGATTCGTAGCTTCATGGGTAAAGTCACGTACTCAGGTAACGAGTCTTACAACCAAACCAGGTTGTTTTCGCCACCATCCCACAATATAATTGATGTAGTAGGAAAAGACGAAGACGACTCTGAAAGTTATTCCGATGGTACACCACCAGAAGAATACAGTGATCATAAAGTTGATGATTATGAGATGAAAATTAAAACTGAAAgagatgaaattttgaataataacgAGCAACCCATAGAGCTGGCAACATAA
Protein Sequence: MKRYRVIEEIKLWYETCVDIPSGSELVLGPREPLNLQDMFGDSTSADEKSDRETASQHSGTVDDREEDEEDESEIRCCVCEQPFTDVDKLDEHLVIKHNYRKDEFKCEYCPKSYSHRPCLIKHKAVVHGEHRKYHCENCPKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCIKCGQSFSTVTSLSKHKRFCDSSTSASTLGAPPPLSLNSMASNNPFSLYRPTCHMPFFPPHFPSYHQIFHPSGPPSGFINPLLFNQLPKLRTEELPEMPSPKRMRSSSTERISPCAERVTPPRVPSVNLKVSPPTAEEAHLTASPAKPTTVPVKMERIEIRPSTPESNNYPTDLSKTSEERSPKHPSPTTSEEGEQPLDLSMTWKKTKVELVENLSPSPRSERASEVSTPPKPVEEKIDVITVEEEKRSMEKMQVTPPMAYPRPIHPMLLDMYRPSFANFTSPSSNDRLLPSPFGPHRFPFLNNLQPQRNFDLLRPGLQNFGGVKPFHDVMQQQTQGKIKDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCRYCERSFSISSNLQRHVRNIHNKEKPFKCPLCERCFGQQTNLDRHLKKHESDDGSGGVAVADSPGSSNENEREDAYFDEIRSFMGKVTYSGNESYNQTRLFSPPSHNIIDVVGKDEDDSESYSDGTPPEEYSDHKVDDYEMKIKTERDEILNNNEQPIELAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00349445;
90% Identity: iTF_01024294;
80% Identity: -