Mdil008807.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megalocaria dilatata
Gene Symbol
GIS1
Assembly
GCA_034642435.1
Location
CM067855.1:69848015-69864079[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 33 0.0029 0.33 12.7 0.3 2 23 90 112 89 112 0.94
2 33 0.00029 0.032 15.8 0.6 1 23 118 140 118 140 0.98
3 33 0.00058 0.065 14.9 4.7 1 23 146 168 146 168 0.95
4 33 4e-05 0.0045 18.5 1.8 1 23 174 196 174 196 0.98
5 33 0.0029 0.33 12.7 0.3 2 23 328 350 327 350 0.94
6 33 0.00029 0.032 15.8 0.6 1 23 356 378 356 378 0.98
7 33 0.00058 0.065 14.9 4.7 1 23 384 406 384 406 0.95
8 33 4e-05 0.0045 18.5 1.8 1 23 412 434 412 434 0.98
9 33 0.0049 0.56 11.9 0.2 2 23 566 588 565 588 0.94
10 33 0.00029 0.032 15.8 0.6 1 23 594 616 594 616 0.98
11 33 0.00058 0.065 14.9 4.7 1 23 622 644 622 644 0.95
12 33 4e-05 0.0045 18.5 1.8 1 23 650 672 650 672 0.98
13 33 0.0029 0.33 12.7 0.3 2 23 804 826 803 826 0.94
14 33 0.00029 0.032 15.8 0.6 1 23 832 854 832 854 0.98
15 33 0.00058 0.065 14.9 4.7 1 23 860 882 860 882 0.95
16 33 4e-05 0.0045 18.5 1.8 1 23 888 910 888 910 0.98
17 33 0.0029 0.33 12.7 0.3 2 23 1042 1064 1041 1064 0.94
18 33 0.00029 0.032 15.8 0.6 1 23 1070 1092 1070 1092 0.98
19 33 0.00058 0.065 14.9 4.7 1 23 1098 1120 1098 1120 0.95
20 33 4e-05 0.0045 18.5 1.8 1 23 1126 1148 1126 1148 0.98
21 33 0.0029 0.33 12.7 0.3 2 23 1280 1302 1279 1302 0.94
22 33 0.00029 0.032 15.8 0.6 1 23 1308 1330 1308 1330 0.98
23 33 0.00058 0.065 14.9 4.7 1 23 1336 1358 1336 1358 0.95
24 33 0.00023 0.026 16.1 0.6 1 21 1364 1384 1364 1385 0.94
25 33 0.0029 0.33 12.7 0.3 2 23 1518 1540 1517 1540 0.94
26 33 0.00029 0.032 15.8 0.6 1 23 1546 1568 1546 1568 0.98
27 33 0.00056 0.063 14.9 4.2 1 23 1574 1596 1574 1596 0.95
28 33 4e-05 0.0045 18.5 1.8 1 23 1602 1624 1602 1624 0.98
29 33 0.0029 0.33 12.7 0.3 2 23 1756 1778 1755 1778 0.94
30 33 0.00029 0.032 15.8 0.6 1 23 1784 1806 1784 1806 0.98
31 33 0.00058 0.065 14.9 4.7 1 23 1812 1834 1812 1834 0.95
32 33 0.00023 0.026 16.1 0.6 1 21 1840 1860 1840 1861 0.94
33 33 0.0029 0.33 12.7 0.3 2 23 1994 2016 1993 2016 0.94

Sequence Information

Coding Sequence
atgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaccttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcattcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatctacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcacgttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcatacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgatatctgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaataGACACAAGTAtctacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcacacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcacgttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttcaaatgtaaacgttgtggaaagagataccaagacaacgatgcatatgaaatacacatcgccaagcatggagatgataagcctcacaaatgctcaaattgcgaaaaaagtttcaattacaaggccgacttaaagagacacaagtatttacacgcagctataaagccattctcttgtgaagtatgtaataaagctttcataaggaacgatcatatgctgaaacatgtgaaatcatacatacgcagggcacataataagactagtggtgttggagggggaaatgagtgtttgcaaactgaagtttccccaaatgcaacgaaccttgacgtcttaccgacggaaacgttcggtaacattgtcgaaatgccaaaagacttcaacaagaaaaacttcgatgataactgttcgatgaaggggaataatggtatatttgtttacccatcagatgatatgaaccttcttccagattcttacacaggcttggcgtacaagtataatgtcacaaacgaagtgaaatggattgataataccaaaaatcccacgcaagttcttccaacgattcaaaatatccattcgttaagcagcaatgatcaacttatttcaattaaagaaaatgttatgtgtgatttagtctgcgtgatatgtaataaaatcttcagcaaggccatgtatctcactcaacacaataaaagtattcactctggtgaaaagcccttctaa
Protein Sequence
MPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDHLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLIQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTHVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSYIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDICSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLNRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSHIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTHVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPFKCKRCGKRYQDNDAYEIHIAKHGDDKPHKCSNCEKSFNYKADLKRHKYLHAAIKPFSCEVCNKAFIRNDHMLKHVKSYIRRAHNKTSGVGGGNECLQTEVSPNATNLDVLPTETFGNIVEMPKDFNKKNFDDNCSMKGNNGIFVYPSDDMNLLPDSYTGLAYKYNVTNEVKWIDNTKNPTQVLPTIQNIHSLSSNDQLISIKENVMCDLVCVICNKIFSKAMYLTQHNKSIHSGEKPF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00965361;
90% Identity
iTF_00965361;
80% Identity
-