Basic Information

Insect: Megalocaria dilatata
Gene Symbol: Klhl6
Assembly: GCA_034642435.1
Location: CM067857.1:18096999-18107611[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2.3e-08 1.4e-05 26.4 0.2 6 108 148 243 143 245 0.85

2 3 3.1e-14 1.8e-11 45.3 0.1 22 107 631 718 625 721 0.91

3 3 0.012 7.4 8.0 0.1 77 109 720 752 718 753 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2.3e-08	1.4e-05	26.4	0.2	6	108	148	243	143	245	0.85
2	3	3.1e-14	1.8e-11	45.3	0.1	22	107	631	718	625	721	0.91
3	3	0.012	7.4	8.0	0.1	77	109	720	752	718	753	0.90

Sequence Information

Coding Sequence: ATGTCGTCTAGTGGATTTGTTGGAACTTGGGAGGTGGAGAGGAATGAACCTTTCCAAGATAAAAACTCATTTAAAGGGTATGCCACATTCTCCTATTATATATTTGCAGATAATAATTGTACATTGTATTCCAGAATACGTTTCCGTTTACATACTGATGGGGATGTAACTTGGTATGTTCCTGAAGAGTTAAAATCAATACCACTCTTTAATTGTTCAATTTATGATACAAATGCTCCATTATATTCCTCACGTGAATCTATATGGGTTAGGTTTGGAGAATATGAGGGTCAAATAATTGAGTTTCAGAGCGATCAAAGAAAACCTAAGGATACAGTAATACTCAGAGCTGAAGGCTTATATACCTTACATTGTAAAAGAGTTCCTGAAGaaatttctgaagaaaagtgTCGAATACCTTTCAGCTTATTACCTGCCTTAGAAGGAGGATtcttttcagatgttaccttaATAtctagtaataataaaaagTTTCATGTGCactcattaattttaaatatcattggACATGGAATTGATTGGCATTCTAAATCTCATCCTTTGTGCAACCTCTCAGAAGATGTGCTGGGCAACATATTACACTTTATGTACACAGAATCTTTACCAGAAAACTTTGATGAGGAGGCCGCAGAAAAAATGATATCGGTGGCAAATCAACATCCATTTCTCAATAAATTGTCATCGATTTGTCAAACATACCTGAAAAATGAAGCTTTTAGAAAACAGTGTATAAACCTAGTGAATGAAATACATGATTCTATGGATAAGCTTATCAAGCATATAAAACCAAAGCATTCTTTGCCTGTGGAATATTTAATAGCAAATCCTGACTATTTATCATCTATGATTAAAAACTGTATTAGGGATGCTGGAATTGggTTTATTAAACTTATTGAACTCTGTGACCTTTATAATAAGAAGAAATCAGAACTGACTAAATATGACCAGTATTCTATCATTCGTTATGGAAACACCAGGTTCTTTGTTTTAGTTGCTCAAGTGAAGCAATTTTTGCAGATTCTGAAAGGATCTTATGGATCTATGAATCGTTATCAAAAGAAGGAAATTGCtacatttttagttcctgaaGTGTCTGGAATATTAGATATGCTAACAGAATTACTGATGCATGTTGATCATGCTTTAGAAAGAATAGTTACTCTTCTAGATGTAGAAGACTTCAACAAATCTAAATCATCTTTTAGAAATTCTTGTTCATATTTTCTGTATcagaaagaaatgaaattccTCAGGAAATTCAGTGAGACCATCAATTGCAGTTACGAGTTACTAATGCAGAAAAGGAGAAATTTCATGGAAATGTCGCCTCTTCTTAAGAGGCATTCTATTTCCTTGAACATAGAGGAAATTGTGGACGAAATGCCCAATTTCTTCTTGGTACGTCTGGAAGAACTGATGGACTACCAAGATAAAATCCTGGAATGGAgggatttcaaatttttcttccaGACTTGTTCCAGTAAAGTGTCAAACTTCATGCAGCTCATGGTCACTCATAGATACGAACTTCAGCAAGTTTCCTCCAGTTTGTGCCTACTGGTACAAAGGGACACTTTCAATCAGTCTATGCAGAACCTCGGATTAATGGAGACAGATTCTAATTCTTCGAACGAGGATAATCTGCCAAAGTCTGCCGAAGATTCTGGAAATTCCAAAAAATGTACTAATGAGATAAATTTTTTGGATTCTCTTTGTATTCCTCCAAAGTTTGACGAGAGTACACTGTCGAAAAATTTGTTAGAACAGTTTAAAAACTCGACAAACACTGACATGGAGTTTGAGATAGTGAAATACTCTGAAGGAGATTTCGCAGATCATTCTACCACGCCTAGGGCTAGAGAGAGGTGTATAATAAAGGCCCATAGGGTGGTAGTAGCCTCTAGATGTGACTGGTTTAGAAAAGCTCTGCTTTCTGGTATGAAAGAAGATATAGATAAaaaaattgttATCTATGAGACAAACAGCGAAACTTATAACATCTTCTTACAGTATTTATACACTGGTAATCTGTGCGCAAATTCAATGACCAGTGAGCAGTTAGTAGATTTGTTGGTATTGAGCGATAAATTCGAAATGGATGTTTTAAAAGGAGCATGTGAGATGGCATTGAAATTCGCAATTGACACAGACAATGCCATCTATTTGTTAAGCTTGGCTGACAGTTATAATGCAAAAACACTAAAGGTTAACTGtatgaatttcatcattaagAACCAGGAGGTAATGGAATCAGATATGTTTTATCAGCTTTCTCGTGAATTGCATGTTGAACTTTACGATCATATCTGGACACAACCTGTCACAGACCCGAGGAGACTTAAGAAGTCTTATCTGAAACATAGACGTTCTTATGAGCCCACTGGTATAGATGGTCATTTTTCACGAATGAATATGCAACATACTGATCAAGACGATACTGATGTACAAGATCAAAATAGACTAGAAAGATGCATATCCCATATAAGAGATATAATAGGAGAGGATGCATCTACGGAACAGCTCAAGCTAATTATCCTAGCCGCCGATTATGATCTCTGTCGAGCAATCAATTTCTACTATgccaaaaataatcaataa
Protein Sequence: MSSSGFVGTWEVERNEPFQDKNSFKGYATFSYYIFADNNCTLYSRIRFRLHTDGDVTWYVPEELKSIPLFNCSIYDTNAPLYSSRESIWVRFGEYEGQIIEFQSDQRKPKDTVILRAEGLYTLHCKRVPEEISEEKCRIPFSLLPALEGGFFSDVTLISSNNKKFHVHSLILNIIGHGIDWHSKSHPLCNLSEDVLGNILHFMYTESLPENFDEEAAEKMISVANQHPFLNKLSSICQTYLKNEAFRKQCINLVNEIHDSMDKLIKHIKPKHSLPVEYLIANPDYLSSMIKNCIRDAGIGFIKLIELCDLYNKKKSELTKYDQYSIIRYGNTRFFVLVAQVKQFLQILKGSYGSMNRYQKKEIATFLVPEVSGILDMLTELLMHVDHALERIVTLLDVEDFNKSKSSFRNSCSYFLYQKEMKFLRKFSETINCSYELLMQKRRNFMEMSPLLKRHSISLNIEEIVDEMPNFFLVRLEELMDYQDKILEWRDFKFFFQTCSSKVSNFMQLMVTHRYELQQVSSSLCLLVQRDTFNQSMQNLGLMETDSNSSNEDNLPKSAEDSGNSKKCTNEINFLDSLCIPPKFDESTLSKNLLEQFKNSTNTDMEFEIVKYSEGDFADHSTTPRARERCIIKAHRVVVASRCDWFRKALLSGMKEDIDKKIVIYETNSETYNIFLQYLYTGNLCANSMTSEQLVDLLVLSDKFEMDVLKGACEMALKFAIDTDNAIYLLSLADSYNAKTLKVNCMNFIIKNQEVMESDMFYQLSRELHVELYDHIWTQPVTDPRRLKKSYLKHRRSYEPTGIDGHFSRMNMQHTDQDDTDVQDQNRLERCISHIRDIIGEDASTEQLKLIILAADYDLCRAINFYYAKNNQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -