Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:354678-363804[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0015 0.092 12.5 1.6 1 23 691 713 691 713 0.97

2 11 0.00022 0.014 15.0 0.0 3 23 802 822 800 822 0.95

3 11 0.15 9.4 6.1 0.2 3 23 1046 1066 1045 1066 0.96

4 11 2.8 1.7e+02 2.1 0.5 1 10 1077 1086 1077 1088 0.91

5 11 0.0011 0.067 12.9 0.4 1 20 1137 1156 1137 1158 0.95

6 11 0.14 8.3 6.3 1.3 3 23 1187 1208 1185 1208 0.95

7 11 5.5 3.4e+02 1.2 0.0 1 23 1228 1250 1228 1250 0.93

8 11 0.87 53 3.8 0.9 1 12 1257 1268 1257 1280 0.89

9 11 0.082 5 7.0 1.5 1 19 1300 1318 1300 1322 0.93

10 11 0.1 6.2 6.7 0.1 1 23 1888 1913 1888 1913 0.96

11 11 0.037 2.3 8.0 1.7 1 23 1915 1937 1915 1937 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0015	0.092	12.5	1.6	1	23	691	713	691	713	0.97
2	11	0.00022	0.014	15.0	0.0	3	23	802	822	800	822	0.95
3	11	0.15	9.4	6.1	0.2	3	23	1046	1066	1045	1066	0.96
4	11	2.8	1.7e+02	2.1	0.5	1	10	1077	1086	1077	1088	0.91
5	11	0.0011	0.067	12.9	0.4	1	20	1137	1156	1137	1158	0.95
6	11	0.14	8.3	6.3	1.3	3	23	1187	1208	1185	1208	0.95
7	11	5.5	3.4e+02	1.2	0.0	1	23	1228	1250	1228	1250	0.93
8	11	0.87	53	3.8	0.9	1	12	1257	1268	1257	1280	0.89
9	11	0.082	5	7.0	1.5	1	19	1300	1318	1300	1322	0.93
10	11	0.1	6.2	6.7	0.1	1	23	1888	1913	1888	1913	0.96
11	11	0.037	2.3	8.0	1.7	1	23	1915	1937	1915	1937	0.97

Sequence Information

Coding Sequence: aTGGCAAGTACtgacaaagaaataaataatccaCATTCAGACCTTGGTGATTGTTCTTCTAAAACAGTAAATGAATCGATATTGTTACAACAGGATGAGCAATCTAACAGTAACAGAAATTCTCGTTTGTCTACCTTAAGAAAAAGATCagttataaatatcaatatgaaAGGGTCATCAAAAGCCAGAAACATAGAAGCTTTGCATAGATTGCTATGTAAACCATTGTCTATAAATGTTACCAGATTATCAATGttagaattacaaaaaatatcaaaagtacaacataaaatacagaaCAATGAAGAAAACAGAAGTCAGATAGGGATAAGAAACAGAATAAAAGTTAAGAGAAAACAGGCTTATGGTTggaaacatataaaaaaatctgcTAAACCCCAATCTGTATCATCTTGTCAAACAATAGTATCCAATAATTCAGATTTAGGCTCACAGGATTCAGTAAAAAGTGTTAAACAACCACATATAAAATTACGCAGAATAGATGaagtaattcataaaatagcaCAAACATTTGCGAAAGTAATCCCAAATAAAGAGTGTAATGCAAGGGCACACACAGATCAAACAGAAAAAGTCCATACTATAGCAAATAGATCAAAGGAAGTAGTATCAGAACCATCAGACATTGATACAGATGAACATATTCAAAGtaataattctccaatttcaacATCTAGTCCagatataaatgaaactttaCAATTAAATGATCAGTTCCAAAATGAGATAGAGGACTCTGACAGTACTGAAATTAACAGAAATGCATGTAATAGAAACTTTAAGAGAAAACGTAAAATTCTGTTTGACTCTGATGATGAGTCTGATAGTAATACTAATAACGTGAGTGGTAATTCGCAAGAAATTAGTTCAAgaagtattaaaatgttaaaattacatacacCAGAtaagaaaacagaaaattatgtTGCTGACAAAGAACACAGTGATTATGAGGAGAATACTATTAACACAAATTCAAGCattattaatgtttcataCGAGAATTTAAATGTAACCGAAAATGTATCTCCAAAATCACATGAAAGTAGCATTAGAAAAAGGATAACACGGCAACAAAATAATGCTGCCACTTTTGTGCCTTCGGATGTTATATGTGCTGAAGAAAGAAATgaacttcaaatattaaaatatgatagtGTTGCAGGTGCAAAAGAGCAAACATTAAGTAATAAAGAATCTCAAAGTCAAATCAAGAAATCACCTATTTCACATGAAagtctgaaaataaaatataatttgcttAAGAACTTAAGAGTTTATTTGATAGAGCTTGATCACATAAAACACTCTAGAGATAACAAATACTCAGCTTTAGAAATAGAACAGTTAACAAGGAAATATAtggaacttttaaataattctgaatttgAGAGTGTGAAATTATCCTTAGTTACTGAAGAAATGGAAGATACACAaaacgatgaaattttaaacacaaATGCTAGCAAGCTTGcaaagaatattgaaataaaacagaaGAAAAGTTCAGATAATGTTGCCGAAGAAATGTCTGAATTGGATACTTCTGCCCATTCAGAGCAATCATCAACTCCATTAGCTTGTAAGGAATTTGTATTGCCATCTTCTCCAGTGAAATCTAGCACTAGAATTTCTAAAGCATCCCGTGTGACTGAACATGTCATTAAGACAGAGAAGTTAAAAGATAGACTGCATAGTTCTATGATGAAATCTCCTAATGAAAAACATTCTCCAAATAAAGAATCATCAGAAACATTAATACGTAAAAGCAGTCCTAAGAAATCAAGTAAGAATATGGAATCTTTAGGAAGTATACAAGCTGATACGTGTGAAAtgatattttctgaaaaaccTGTTGTAACTCATAATGAAAAAGTTCTTGTCTCTGGGAGAAAGACGTTTGTAACTAAAATACATGCAAAAACCGTGAATATCATAAATCCTAAAGTAAatacgaaaaaaaatattacatccTGCTCCTCAATCATTTCTCCAGTTAAGAAGAAACCTGTGGAGAAGaaagataataatagtaaaagtattaattacaaatgtattGTCTGTGATCTTCgctttgaaaattattctgcTTTGCAACACCATTTAACTACGCACACACAGAAGCAAAGTAATGTTTTACCAAATACATCAAAAGAATCTGCTGCAATTCAAACTGATAGTTCTGAGAATATCCAAGAAGCATTACTTGATTCTCCAGAAGCAACAGAATCAGCAGAATCGTCTAGACAAACACACAACACTAAAAGTAGTAAACAACAAAGTAAGGGTACTTCAACCCAAGACTTACCATCTAAGAAGAGaagttatttttcaaaacaacGATCTAAGTTTATGAATATGCTTTGTAAACCAACTGCTTGTGATATTTGTTCTAAAGTTTTTCCAACAGCAACTGATTTAGCAGCTCATATTTTCTTGCATACAGAATATGAATTGCAGAAAGCTTATGAACTTGCCAAACATAAGAAAAGTAATGTAAATGAAGGAACAAAGAGTAAAAAACCTAAacaaactaaaaatactaaagaATTTGACAATGAAAGTAGGACAAGTCTTATAGTTGAGAAGCCTGCAGAGGTTGTTAGcgaacaagaaaaattaacagCTGCAATGGATCACAATGAATCATTATCAACTGAAGATTTGAAGGTAACACATTCTGAAAAATCAACAACAGCCACAACAACATTAACAACAATACCAATTGCAACTGCATCATCAACAATATCAACAGTAACAGAACCATCACTGCCAGTAATAACAGCAataacagcagcagcaacaacaacaacaataacaatagcAACACCAACATCAGTTGTGAATGAAACTGGTTCTGAAGGATTACAATCGCATTCAACTGAAAGTAAatcagaaaaaagaaagacaaAGAAATCCTTTAAAATATGTGAATGTCATGGTAAATTAGAACCCGATAACAATTGCTTGCAAATTGAAATGGTTCTCCTTTGTCACACTTGTAAAGTGCTGTTTCGAAGCATGGAATGTTTTGATACTCATTATGATCTTCCTGAATATGAACTCTGCGGTAAAAATCGTGGTAATCGAAGCAGAACTCCAAATATATTGTGTGCTGTGTGCGGTATAATATTCAACTCTGTTCAAGAGGTACGACATCATTTAGAAAACCATGCTCGCGTCAGGCAAAGTTGTACATTGGATTTTCgatgtaaaatttgcaaagttgtgTTTATTGGAATTGGAGCTCAATTTTACGTTCATTGGTCAAAACATTTACAAGATCCTTATTGGAAAGCTGATGAATCAGCATTTCCAATACATTCAGTGGTAAATGTACTAGACCAGAacaaagaaacagaaaattatcTTCAAATAGCAGaatatatttgttcaaaatgtaGAATACCTTTTATTACTGAAAGTGATTTGAAAAGACATCATGTAAAATGTAAGATGTCCAATTCAAATACAAGTGGAACTAGTAGTAACAGTAATACTAATGTGGAGAAATCTCTAGAAATAGAAGTGAATTGTAGTTTATGCAATGATGTTTTTACTGAAAAAacaacattttataaacatgTCAGAAACAAACATAATTTCATTAGTGAACCTCAGTTTGTTTGTGTGTCTCTTACATTAATCAAAACAGCATacatttgcaatatttgtaTGGAAATATCTGAAAGTATAGACGACTTTGAAGATCACTGGTTAAAACATAGTACAGCTATTGTATACTTCACTTGTACATATTGTTCAAAAGCATATTGTGATGGTTTAAATGCTTTTTTAGAACATGCTAGGATACATGAAGTTAATGTGAAACAGTATGTACTATCTTGTACAGTGAAGTACGAAAATGCCGAATTTGTTTGTAAACATTGTAATGTTGGttttaattccaaaaaatCCTTTGATGAACATGatgttattcataaaataaatatattgaattctcAGAATAATAAGGCTCAAGACcacgaaatttctatattagaGTCAAATATaaaccaaatttctaatatgttGGAAATAAATAGATTGAGCACTGAAAAACAACAGAAAGATGCTCAAAAAGAAAGTCGTACAAATCAGGCAAGTAAACATACGAATGGAAGTTGTTCAATAGAATCTGATAAAGATAAGGACAGAGAAAAATTAATCAGCATATTGGAGGGAAATGAAGATGATTCAGAACATGAATTGATAATAGATTGGATAGAAAAACCAGAagaggaaaataaattaccagaggaaggaagaaataaagataaaCAAACTACACTGGATAATATATTAACTACACATTCTATTGTACAAAGTTctacagtttcaaaaaataGTACAGCTAATGCATCCACAAGTCACGTAATAGTACATGAGTCTCCAAAAAGTAGTACAGCTTCTGAAAACATTGTTTCAACATCTTCTCAAACTGAAAATCCAAAAGTATCTACAGACGTTCCAGTTAAACCAGTGATTCAAGATAcaattgaaattccaaaagaATCACAATGTTTAAATGTCGAAAACGCTGACCATGATTATGCTGGAAATGTAACTAAAGATCAAAAGGAGTCAACgacattaaagaaaaatagtcCTCCAAAACCAAAACAAGGGTTCTTACGGGTAAAATCTCTTGCAGAACTTACAAACAGTACAAAACCAGTACCAGAGCATACTGAAAACGTTAATCAACGTTTGCCAACTCAtcttattttcattcaaaagAATAAACCGAATGAAAGTTCAAAACAACCTGGTTCTCTACCTTTTTCTGCAGTTCCTGCAAAACAAATTACAGTTGCCACTGCATCGATAATAAACGACCAACAGTTGAAGCAAGCACAAATGCATATAAATCAAAACAATCATGCAGCTGGTTTTGTACAGAGTTCAACATCAGggtatcataaaaatttacctGCTTGCAACATTGCACGAACAACAACGAGTATACCACGTTCTGCTACGAAAAGCGATAATGCATCTACTAAGTCAGCAGCAGGTTGTTCTAACACACAAAATCAACGAGCAGGATACACAGCACCTACTTTTATGGATTCATATATAACTTCcttaaataatacaatgcaTTCAAATCCACAAGTAACAAGACCATCAAATGCTAACTCAAAATCTAATAGGTATAACAATGCTGGTCACCAAATACCAACCAGAATTAACAACCAGAATTCTAAACACTATAAGCATTCTCcacaaattatttctttccaATATCCTTATGGAATTAGCAGCTCAAGTAACAGTACTGAACCTCAGCAAAAAAGTCAAGAGATGGTGATTAATCCAGTAACAGGAGAAGCTTCTACCATCTTTTACACAACTCCTAATAATTCCACAGGCGGTATGTCAATAGTAATTAATCAGACTACACCTGCTGTACAAAATATGCccacaataaatattttgggACAGGAACAGCAACAACTGTATCAGCCACAAGTTTATAGTGAACCTGCAATGATTGCGGACCATTCATATGCACAATCgaATGCAACTAATTTTTCTGCAACAAGCAATGTTTATCAGATAGTAACTAGCGAATATCAAGTACCAGAAAGAGAAACTTTACCTACCTATAAAGTTAATTTACAATCaccaatatttatttgttcttaTTGTCCGGACGTTAGGTCTTTTCTGTCTGCTGAACAATTAGAAATGCATATGAATATAGATCACAATTTCATATGCAATACTTGCGGTCAACGTTTGTACAGTTTTGAGAAGTTAAATATGCACAAAATGAAACAtggttttatttaa
Protein Sequence: MASTDKEINNPHSDLGDCSSKTVNESILLQQDEQSNSNRNSRLSTLRKRSVININMKGSSKARNIEALHRLLCKPLSINVTRLSMLELQKISKVQHKIQNNEENRSQIGIRNRIKVKRKQAYGWKHIKKSAKPQSVSSCQTIVSNNSDLGSQDSVKSVKQPHIKLRRIDEVIHKIAQTFAKVIPNKECNARAHTDQTEKVHTIANRSKEVVSEPSDIDTDEHIQSNNSPISTSSPDINETLQLNDQFQNEIEDSDSTEINRNACNRNFKRKRKILFDSDDESDSNTNNVSGNSQEISSRSIKMLKLHTPDKKTENYVADKEHSDYEENTINTNSSIINVSYENLNVTENVSPKSHESSIRKRITRQQNNAATFVPSDVICAEERNELQILKYDSVAGAKEQTLSNKESQSQIKKSPISHESLKIKYNLLKNLRVYLIELDHIKHSRDNKYSALEIEQLTRKYMELLNNSEFESVKLSLVTEEMEDTQNDEILNTNASKLAKNIEIKQKKSSDNVAEEMSELDTSAHSEQSSTPLACKEFVLPSSPVKSSTRISKASRVTEHVIKTEKLKDRLHSSMMKSPNEKHSPNKESSETLIRKSSPKKSSKNMESLGSIQADTCEMIFSEKPVVTHNEKVLVSGRKTFVTKIHAKTVNIINPKVNTKKNITSCSSIISPVKKKPVEKKDNNSKSINYKCIVCDLRFENYSALQHHLTTHTQKQSNVLPNTSKESAAIQTDSSENIQEALLDSPEATESAESSRQTHNTKSSKQQSKGTSTQDLPSKKRSYFSKQRSKFMNMLCKPTACDICSKVFPTATDLAAHIFLHTEYELQKAYELAKHKKSNVNEGTKSKKPKQTKNTKEFDNESRTSLIVEKPAEVVSEQEKLTAAMDHNESLSTEDLKVTHSEKSTTATTTLTTIPIATASSTISTVTEPSLPVITAITAAATTTTITIATPTSVVNETGSEGLQSHSTESKSEKRKTKKSFKICECHGKLEPDNNCLQIEMVLLCHTCKVLFRSMECFDTHYDLPEYELCGKNRGNRSRTPNILCAVCGIIFNSVQEVRHHLENHARVRQSCTLDFRCKICKVVFIGIGAQFYVHWSKHLQDPYWKADESAFPIHSVVNVLDQNKETENYLQIAEYICSKCRIPFITESDLKRHHVKCKMSNSNTSGTSSNSNTNVEKSLEIEVNCSLCNDVFTEKTTFYKHVRNKHNFISEPQFVCVSLTLIKTAYICNICMEISESIDDFEDHWLKHSTAIVYFTCTYCSKAYCDGLNAFLEHARIHEVNVKQYVLSCTVKYENAEFVCKHCNVGFNSKKSFDEHDVIHKINILNSQNNKAQDHEISILESNINQISNMLEINRLSTEKQQKDAQKESRTNQASKHTNGSCSIESDKDKDREKLISILEGNEDDSEHELIIDWIEKPEEENKLPEEGRNKDKQTTLDNILTTHSIVQSSTVSKNSTANASTSHVIVHESPKSSTASENIVSTSSQTENPKVSTDVPVKPVIQDTIEIPKESQCLNVENADHDYAGNVTKDQKESTTLKKNSPPKPKQGFLRVKSLAELTNSTKPVPEHTENVNQRLPTHLIFIQKNKPNESSKQPGSLPFSAVPAKQITVATASIINDQQLKQAQMHINQNNHAAGFVQSSTSGYHKNLPACNIARTTTSIPRSATKSDNASTKSAAGCSNTQNQRAGYTAPTFMDSYITSLNNTMHSNPQVTRPSNANSKSNRYNNAGHQIPTRINNQNSKHYKHSPQIISFQYPYGISSSSNSTEPQQKSQEMVINPVTGEASTIFYTTPNNSTGGMSIVINQTTPAVQNMPTINILGQEQQQLYQPQVYSEPAMIADHSYAQSNATNFSATSNVYQIVTSEYQVPERETLPTYKVNLQSPIFICSYCPDVRSFLSAEQLEMHMNIDHNFICNTCGQRLYSFEKLNMHKMKHGFI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00964740;
90% Identity: iTF_00962834;
80% Identity: -