Mrot007229.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile rotundata
Gene Symbol
-
Assembly
GCA_000220905.1
Location
NW:167206-170480[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 9.9 6.1e+02 0.4 0.4 1 7 107 113 107 115 0.90
2 16 3.6 2.2e+02 1.8 0.9 1 10 312 321 312 334 0.76
3 16 0.0048 0.3 10.9 1.3 1 23 342 365 342 365 0.92
4 16 0.064 4 7.3 4.2 1 22 371 392 371 395 0.89
5 16 0.061 3.7 7.4 5.3 1 23 477 499 477 499 0.93
6 16 0.0055 0.34 10.7 0.5 1 23 506 529 506 529 0.91
7 16 0.00066 0.041 13.6 3.1 1 23 535 557 535 557 0.97
8 16 6e-05 0.0037 16.8 2.3 1 23 563 585 563 585 0.99
9 16 3.3e-06 0.0002 20.8 2.2 1 23 591 613 591 613 0.98
10 16 0.00079 0.049 13.3 0.1 1 23 626 649 626 649 0.95
11 16 9.4e-05 0.0058 16.2 4.3 1 23 665 688 665 688 0.96
12 16 0.00021 0.013 15.2 0.8 1 23 696 719 696 719 0.98
13 16 0.00044 0.027 14.1 0.7 1 23 725 747 725 747 0.97
14 16 0.00034 0.021 14.5 5.2 1 23 753 775 753 775 0.98
15 16 2.8e-06 0.00017 21.0 1.5 1 23 781 804 781 804 0.98
16 16 0.00024 0.014 15.0 0.9 2 23 809 830 809 830 0.97

Sequence Information

Coding Sequence
ATGGATACAATAAGGAATACATTAATATGTCGTTTATGTGGTGTTAATATTGTAGaaggaaaatgtaaaaacatttTCGAAGGATCAACTAATTTGGTACAGAAGATAAAAGAAACATTACCAATTTCAATATCTATAGATGATAATGGTTCAAAACATCTATGCTTGCCATGTTAtgacaaaattattctttattataaatttacccAAGAAGTATTAgaatattccaaaaaattaGAGAACGCGTCAGAAATAAAGTCTTTTTTTGATTTATCCAAAGAAATAACAgacttttcaaaaattcatagtGATGCTGTATATACATGTCCAAATTGCAATGTAggtttaatgattttattagtTAGTAATTCACAAGGCTGTGATTATACCTTTCAAATCTCATTAGCTATGGTAAATCATTCTGAGAAGAAACATGTTATacaagagaaaaatattgagaTACATAAAAACTTAATACATGCCAATAATACTAAGAACAATATATATtcaaaacatgaaaataaaacaacttCTGAAAGTGTTGAAAATGTTCCTAATTTAATAAGTCTTACGTTACCTGTATTGcaacaagaagaaaatataaattatatcaatgtattatccaataaagaaaatacagaaactgAAGAGTGGAAaaagcagaaaaaaaaatttaaagaatctaATTGTCACAACCATTCTATTCATTCATCAAATGTATCCTACACGTCTAATGAGAACCTACTGAACTGTGATTATGATTCTGCAGATCAATTAGTAAAAGTTGAGAATGAAAGTGATAATGCTTATTGGTTTGATAGTGAGACTGACTGTAAAAGTGAAAAAGATGTATATATGACTGAATCACaagatattatattaaagaaaGATAATGCACAAGAAGAAGATGATTCGTATAAGTcttgtttaaaatatgaatgcaaATTATGTGGAGCACGTTATCTTTCACATTTAAAATACGAATTTCATATGGAAAGACATAAGTTAggtaaaatgtgtaaatatgAATGTACAGTATGTGATAAAGAAACAACtagtgaaaatttattatgggATCATTATTTTCACACCCATAAAAGTTTACAACGTTATGTTTGCTTAGAATGcggaaaattatttactaaacGATCTAGATTGAACTGTCatcaaaagaattataaaCACTCTGGTATAAAACAAATACAAGTCGATACCAGTAAAGATACTACTGGTGAAGATTTTATACAAAAGGTAATAGCAACAACAAACCAAGAAAAAGTTTCTGTAAACTGTAATCTCTgtggtaaattaatttcagaccTAGATCCAGATGCTATTAATGATTTAGTTACATGTATTGATTGTGAAGATTCTACACTTTCTTTAATGGTAGATGGAAATGAAACTAAAGTAATCTCTCCAAGACAATATCATTGTTCTAAATGTCCTAAGCATTTTGTACGGAAAGAACGATTAGAATTCCATGAAATGAGACATAATGAGAAtatgaatgaatttatttgtagTACTTGTGGAAAAGATTTTAGAGCTGAAAATTCCTTGTATGAACATTATCTTTTTGTTCATAAAGGAGCAAGACCCCATATCTGTGAATTATGTGGTAAATCATTTCAGTTAAAGGCTAGATTAAAAGAACACCATAGAATTCATACAGGTGAAAGACCATATCAGTGTGATATTTGTGGTCAACGATGTAGAACTACAAATGCCTTAAAACTTCATAGAAAAATTCACTTTTCTCATAATAGATATACTTGTAATGTCTGCAATAAATCATTTAGtaagaaacaaaatatgaatgaacatttagaaaaacattggaaaaatgataaaagtgtAACATTACCACAGCTATTTACATGCCCAATTTGCTTAGAAGATTTTCCGACATATCGAATGTTAAAATACCATATGATAgaaatacatgaaataaataatcaagatccaattttaattaagcaaAAGCCATGGTATGAATGTACTGAATGTCATGAAAAGTTCAAACATCAAATGTCTTTAAAAGCACATAAAGAGAGAGTACATGAAGGAAGAGTAGATCCAAATTACCAATGTGATACTTGTAATGCAACATATAAAGTAAAACAACTTTTAGTGAATCATATTAAAAGCAAACATAATGGTGAAAGACGCTATAAATGTGCACAGTGTGAGAAAGGATTCAATGATACTAAATCTTTATATAATCATGTATTGTTACATACTGGTAAAAAACCATTTGTTTGTGAATATTGTAATATGAGTTTTAGAAGAAAAGACTCTAGAGACCATCATCGTAGAAAACATACAGGTGAACAACCTTATCAATGTCCAGACTGTGGTGAATCATTTTCTACTTATAATAATAGATCTAAGCATCGAAAACGAGAGCATGGAAAAGATCCTGAATGTCCTGAATGTGGAGAAAAGTGTAGTAATCAGCAGGAAATTAGAATTCATCTAAATAAACATCTtggagaaaaattgaaaaaactgAAGAATATACAACCCGAAATGATGTAG
Protein Sequence
MDTIRNTLICRLCGVNIVEGKCKNIFEGSTNLVQKIKETLPISISIDDNGSKHLCLPCYDKIILYYKFTQEVLEYSKKLENASEIKSFFDLSKEITDFSKIHSDAVYTCPNCNVGLMILLVSNSQGCDYTFQISLAMVNHSEKKHVIQEKNIEIHKNLIHANNTKNNIYSKHENKTTSESVENVPNLISLTLPVLQQEENINYINVLSNKENTETEEWKKQKKKFKESNCHNHSIHSSNVSYTSNENLLNCDYDSADQLVKVENESDNAYWFDSETDCKSEKDVYMTESQDIILKKDNAQEEDDSYKSCLKYECKLCGARYLSHLKYEFHMERHKLGKMCKYECTVCDKETTSENLLWDHYFHTHKSLQRYVCLECGKLFTKRSRLNCHQKNYKHSGIKQIQVDTSKDTTGEDFIQKVIATTNQEKVSVNCNLCGKLISDLDPDAINDLVTCIDCEDSTLSLMVDGNETKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKDFRAENSLYEHYLFVHKGARPHICELCGKSFQLKARLKEHHRIHTGERPYQCDICGQRCRTTNALKLHRKIHFSHNRYTCNVCNKSFSKKQNMNEHLEKHWKNDKSVTLPQLFTCPICLEDFPTYRMLKYHMIEIHEINNQDPILIKQKPWYECTECHEKFKHQMSLKAHKERVHEGRVDPNYQCDTCNATYKVKQLLVNHIKSKHNGERRYKCAQCEKGFNDTKSLYNHVLLHTGKKPFVCEYCNMSFRRKDSRDHHRRKHTGEQPYQCPDCGESFSTYNNRSKHRKREHGKDPECPECGEKCSNQQEIRIHLNKHLGEKLKKLKNIQPEMM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01123228;
90% Identity
iTF_01123228;
80% Identity
-