Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:633054-636574[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.56 34 4.4 0.2 2 20 330 348 329 350 0.91

2 15 0.0027 0.17 11.6 2.6 2 23 449 471 448 471 0.93

3 15 6.3e-05 0.0039 16.8 0.2 2 23 478 499 477 499 0.96

4 15 2.5e-06 0.00015 21.2 3.4 1 23 505 527 505 527 0.96

5 15 3.7e-05 0.0023 17.5 3.7 1 23 536 558 536 558 0.96

6 15 9.3e-06 0.00058 19.4 1.6 1 23 564 586 564 586 0.97

7 15 1.4e-06 8.9e-05 21.9 0.3 1 23 591 613 591 613 0.97

8 15 0.0064 0.39 10.5 3.7 1 23 620 642 620 642 0.99

9 15 0.00011 0.0067 16.0 1.4 2 23 662 683 661 683 0.97

10 15 4.1e-05 0.0025 17.4 0.7 2 23 691 713 690 713 0.96

11 15 0.0049 0.3 10.8 1.4 1 23 719 741 719 741 0.93

12 15 0.0019 0.12 12.1 6.3 1 23 747 769 747 769 0.98

13 15 1.7e-06 0.00011 21.7 5.1 1 23 775 797 775 797 0.98

14 15 3.7e-06 0.00023 20.7 2.7 1 23 803 825 803 825 0.98

15 15 0.00049 0.03 14.0 2.4 2 23 831 852 830 852 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.56	34	4.4	0.2	2	20	330	348	329	350	0.91
2	15	0.0027	0.17	11.6	2.6	2	23	449	471	448	471	0.93
3	15	6.3e-05	0.0039	16.8	0.2	2	23	478	499	477	499	0.96
4	15	2.5e-06	0.00015	21.2	3.4	1	23	505	527	505	527	0.96
5	15	3.7e-05	0.0023	17.5	3.7	1	23	536	558	536	558	0.96
6	15	9.3e-06	0.00058	19.4	1.6	1	23	564	586	564	586	0.97
7	15	1.4e-06	8.9e-05	21.9	0.3	1	23	591	613	591	613	0.97
8	15	0.0064	0.39	10.5	3.7	1	23	620	642	620	642	0.99
9	15	0.00011	0.0067	16.0	1.4	2	23	662	683	661	683	0.97
10	15	4.1e-05	0.0025	17.4	0.7	2	23	691	713	690	713	0.96
11	15	0.0049	0.3	10.8	1.4	1	23	719	741	719	741	0.93
12	15	0.0019	0.12	12.1	6.3	1	23	747	769	747	769	0.98
13	15	1.7e-06	0.00011	21.7	5.1	1	23	775	797	775	797	0.98
14	15	3.7e-06	0.00023	20.7	2.7	1	23	803	825	803	825	0.98
15	15	0.00049	0.03	14.0	2.4	2	23	831	852	830	852	0.95

Sequence Information

Coding Sequence: aTGATTGCACACAAAATGACGATAATTTGTGCCGTAAAGAATTGTAAATACTCATCAGGTAATGAAGAATCAGGGCACAtcatgtttattaattttccaaatgatGATAGCTCAAAAGTATGGGCACAACAGTGCGGTAGGACAGACCTTTTGATGAAATCTAACGAAGAACtgcatttgaattattatatatgttcTCATCACATAGAAGACCATTATTTCATAAGCAAGTTAGACCCAGTTGTAATAGATCAGCATGCAATTCCGACATTATTTGAAACAGATACAAAGgagaaaagtttgaaagatgtttttgatgaaaatgaacaaatagaAGTAACAGACAGCGTTGTATTATCTTACTGTGATATGAACATCGAAGTAGATCAGTATCATGATATTGGTATTAGATTATCAAATGTATGCAGGATATGTGGAGAATCATGTGAGAATGGCATAGAAATATTTGCAGGAAAGGGGATCGAACTAAAgttgaaagagaaaataaactTACATCTTCCAATAACAGTAGATATGGATGATTTAATGCCTCAAAAATTATGCATGAATTGCTGTGATAAATTGGAAGTAGTACATTCGCTTGCTATAAGTTCTTTGAAAACagatatgaaattgaaaaaatttctaaatattaataacACAAATTATGATAGAAGGTATGATGAAATAGTTAAGAAATGTTCTATAGAGATTAATGAAGAATTACATATCACTCAAAAGGATAATCAAATTACATTGGTAGAGTTGCCTCCTAATAGCATAGAGGATACTTCTATGAATCAAGGAATCactagaaaattaaatcactTAGAACAGATTGATACTGTGAACAACATAGAAAGTGAGATGCAATccgaattaaataattttatctgcaCATCTagtaaaacgaacaaagaagaTGAATCTGAAAATCAAAATACACAACATTACCAGGAGAATGGTGAAACcgttttcaataaaatttcatgtttttactgtagaaattcttttgaaagtcaagaagtatttgaaaatcataaaatattatgttataacaaagaaattaCAGCACAAAAACGagaaatagttaataataatataaacagaaGGGATTCCAATAACATGGAAATAGTGGATGTACAATATAGTAGAGATTCTAACACTCATCacaagaattttgaaaatgaacgaAATTTAGATGAACATAAGCTTTCATATTGTACACTTTTTGATCAAGAATCGTATAAACTTTCTATTAAATCACATACAAATGAAGAACAGTGCAGAACTATTAAAGAGTTGCACAATATCAATGATCTTGCAGTATCGGAAATTAATAAGAAGTGTGGTCACTGTGATACAGTTTATGGTACTAAAAAGGAACTATCGAATCACATTGCAGAATGTCATAAGGGTCAATTGTTGTTGAAGTGTACTATGTGTGACAAGAGTTACGAAAAATGGTCTAGTTTAGATGTACATGAAGCTACTCATAGAATAGATAAACCTTATCTGTGTGATTTATGTGGCAAAAGTTTTAAACATTCTAACAATTTAAGAGGTCATAAAAGAACTCATTTAGATGATTCAAAGAAAAAGCGACACATCTGCGAAATTTGTGGACACGCATTCAGATCTAGATTTCATTTGGCTGAACACATGAATCAACATAATGGAAATAAACCTTATGCTTGCGATAAATGTGGGAAAACTTTTTACAAAAGAATACAATTGAGACAGCATACATTATCCCATggtttaaataaacatatttgtcCAATATGTGGAGTGGCATTTAATCGTAAAGGAAATATGAATGCACATCTTAAACGTCATAATAATGGAAATGGTGTATATACATGTAGTGTTTGTGCGTACAGATGTAACTCAATGAgcgaattaaaattacataggAAAAAGCACACAGAACAGGACATCATAGACAGTATACAAAAAAAGTGTATTGACAAAGCTGCGTTGCAATGTAAAAGTTGTAACAGGGTATTTTCTACGCGAACAGTATTATTGAACCATGAACGAACTCACAGAAGAGAAAAACTAATGATAGAATGTAATATTTGTGGAAAGAAATTGTCGAGTAGAAGTACGTTAAGCTATCATAAACGCTCTGTACATTCTACAGAGAGACCACACATGTGTCAATATTGTGGAGAATCGTTTGTCTCCAAAGAAGCGCACCTTATACATGAAAGGATACACACTGGGGAACGTCCTTACGTTTGCAAAGTGTGTAACATGAAGTACAAATGCTCAAGCAATCTCTGTCAACACATGAAGATCCATTCCGGTGTTAAACCTCATAAGTGTTCGTACTGTAACAAATGTTTTACCCGGAAGGGCGCACTAAACGTTCATGAGAGAATTCATACTGGAGAGAAACCATTTTCCTGTGATACATGTGGCAGGACATTTACACAAAAGAATGACATGCTGAAACACACCAAAACGCATCAGACTAAATCGCTACATTGTGAACAGTGCGATCAAACATTCACAAGAAAGAAAGATATCTTGAAACATATTACATTGCATGAACATAATGATCCTATAATTCAAGAGTACATAGAAATTGAACAGCAAGTGGAGACTTACAGTATGGATATACCTTGTTctcaatttgaataa
Protein Sequence: MIAHKMTIICAVKNCKYSSGNEESGHIMFINFPNDDSSKVWAQQCGRTDLLMKSNEELHLNYYICSHHIEDHYFISKLDPVVIDQHAIPTLFETDTKEKSLKDVFDENEQIEVTDSVVLSYCDMNIEVDQYHDIGIRLSNVCRICGESCENGIEIFAGKGIELKLKEKINLHLPITVDMDDLMPQKLCMNCCDKLEVVHSLAISSLKTDMKLKKFLNINNTNYDRRYDEIVKKCSIEINEELHITQKDNQITLVELPPNSIEDTSMNQGITRKLNHLEQIDTVNNIESEMQSELNNFICTSSKTNKEDESENQNTQHYQENGETVFNKISCFYCRNSFESQEVFENHKILCYNKEITAQKREIVNNNINRRDSNNMEIVDVQYSRDSNTHHKNFENERNLDEHKLSYCTLFDQESYKLSIKSHTNEEQCRTIKELHNINDLAVSEINKKCGHCDTVYGTKKELSNHIAECHKGQLLLKCTMCDKSYEKWSSLDVHEATHRIDKPYLCDLCGKSFKHSNNLRGHKRTHLDDSKKKRHICEICGHAFRSRFHLAEHMNQHNGNKPYACDKCGKTFYKRIQLRQHTLSHGLNKHICPICGVAFNRKGNMNAHLKRHNNGNGVYTCSVCAYRCNSMSELKLHRKKHTEQDIIDSIQKKCIDKAALQCKSCNRVFSTRTVLLNHERTHRREKLMIECNICGKKLSSRSTLSYHKRSVHSTERPHMCQYCGESFVSKEAHLIHERIHTGERPYVCKVCNMKYKCSSNLCQHMKIHSGVKPHKCSYCNKCFTRKGALNVHERIHTGEKPFSCDTCGRTFTQKNDMLKHTKTHQTKSLHCEQCDQTFTRKKDILKHITLHEHNDPIIQEYIEIEQQVETYSMDIPCSQFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00963345; iTF_00964626; iTF_00961979; iTF_00962661; iTF_00961878;
90% Identity: iTF_00962661;
80% Identity: -