Mlea026872.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Megachile leachella
Gene Symbol
-
Assembly
GCA_963576845.1
Location
OY756259.1:5688285-5691383[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 9.7 1.4e+03 1.0 0.3 2 19 325 342 324 344 0.84
2 15 0.0039 0.58 11.6 2.6 2 23 443 465 442 465 0.93
3 15 8.3e-05 0.012 16.9 0.2 2 23 472 493 471 493 0.96
4 15 3.5e-06 0.00053 21.2 3.4 1 23 499 521 499 521 0.96
5 15 5.4e-05 0.0081 17.5 3.7 1 23 530 552 530 552 0.96
6 15 1.9e-05 0.0028 18.9 0.9 1 23 558 580 558 580 0.97
7 15 2.1e-06 0.00031 22.0 0.3 1 23 585 607 585 607 0.97
8 15 0.058 8.7 7.9 5.6 1 23 614 636 614 636 0.99
9 15 4.2e-05 0.0063 17.8 1.0 2 23 656 677 655 677 0.97
10 15 5.9e-05 0.0089 17.4 0.7 2 23 685 707 684 707 0.96
11 15 0.007 1 10.8 1.4 1 23 713 735 713 735 0.93
12 15 0.0027 0.41 12.1 6.3 1 23 741 763 741 763 0.98
13 15 2.5e-06 0.00037 21.7 5.1 1 23 769 791 769 791 0.98
14 15 5.3e-06 0.00079 20.7 2.7 1 23 797 819 797 819 0.98
15 15 0.0005 0.075 14.5 1.9 2 23 825 846 824 846 0.95

Sequence Information

Coding Sequence
ATGACGATAGTTTGTGCCGTAAAGAATTGTAAATACTCGTCAGGTAATGAAGAATCAGGGCACATcatgtttattaattttccaaatgatGATACCTCAAAAGTATGGGCACAACAGTGCGGTAGGACAGATCTTTTGATGAAATCTAACGAAGAACTGCATTTGAATTATTATATATGTTCTCATCACATAGAAGACCATTATTTCATAAGCAAGTTAGACCCAGTTGTAATAGATCAGCATGCAATTCCGACATTATTTAAATCAGATATAAAGAAGAAAAGTTCGAAAGATGTTTTTGATGAAAATGAACAAATAGAAGTAACAGAGAGCGTTGTATTATCTTACTGTGATATGAACATTGAAGTAGATCAGTATCATGATATTGGTATTAGATTATCAAATGTATGCAGGATATGTGGAGAATCATGTGAGAATGGGATAGAAATATTTACAGGAAAAGGGAGCGAACTAAAGTTGAAAGAGAAAATAAACTTACATCTTCCAATAACAGTAGATATGGATGATTTAATGCCACAAAAATTATGCATGAATTGCTGTGATAAATTGGAAGTAGTACATTCGCTTGTTATAAGTTCTTTGAAAActgatatgaaattaaaaaaatttctaaatattagtAACACAAATTATGATAGAAGGTATGATGAAATAGTTAAGAAGTGTTCTATAGAGATTAATGAAGAATTACATACCACTCAAAAGGATACTCAAACTACATTGGTAGAGTTGCCTCCTAATAACATAGAGGATACTTCTATGAATCAAGAAATCACTAGAAAATTAAATCACTTAGAACAGATTAGTACAGTGAACAACATAGAAAATGAGATGCAATccgaattaaataattttatctgcACACCTAGAAAAACAAACAAAGAAGATGAATCTGAAAATCAAAATACACAACATTACCAAGAGAATGATGAAAccgtttttaacaaaatttcatgtttTTACTGTAGAAGTTCCTTTGAAAgtcaagaaatatttgaaaatcataaaatattgtGTTATAACAAAGAAATTACAGCACAAAAACGAGAaatagttaataataatataaatagaagGGACACCAACAACATGGAAATAGTGGATGTACAATATAGTAGAGATTCTAACACTcataagaattttgaaaatgaacaaaatttagaTGAACATAAGCTTTCATATTGCACACTTTTTGATGAAGAATCGTATAAACTTTCTATTAAATCACATACAAATGAAGAACAGTGCAGAACTATTAAGGAGTTACACAATATCAATGATCTTGCAGTATCGGAAATTAATAAGAAGTGTGGTCACTGTGATACAGTTTATGGTACTAAAAAGGAATTATCGAATCACATTGCAGAATGTCATAAAGGTCAATTGTTGTTGAAGTGTACTGTGTGTGACAAGAGTTATGAAAAATGGTCTAGTTTAGATGTACATGAAGCTACTCATAGAATAGATAAACCTTATCTGTGTGATTTATGTGGCAAAAGTTTTAAACATTCTAACAATTTAAGAGGTCATAAAAGAACTCATTTAGATGATTCAAAGAAAAAACGACACATCTGCGAAATTTGTGGACACGCATTCAGATCTAGATTTCATTTGGCTGAACATATGAATCAACATAATGGAAATAAACCTTATGCTTGCGATAAATGTGGGAAAGCTTTTTACAAAAGAATACAATTGAGACAGCATACATTATCCCATGgtttaaataaacatatttgtCCAATATGCGGAGTGGCATTTAATCGTAAAGGAAATATGAATGCACATCTTAAACGTCATAATAATGGAAGTGGTGTATATACGTGTAGTGTTTGTGCGCATAGATGTAACTCAATGAGCGAATTAAAATTACATAGGAAAAAGCACACAGAACAGGACATCATAGACAGTATACAAAAAAAGTGTATTGACAAAGCTGCGTTGCagtgtaaaatttgtaataggATATTTTCTACGCGAACAGTATTATTGAACCATGAACGAACtcacagaagagaaaaattaatgATAGAATGTAATATTTGTGGAAAGAAATTGTCGAGCAGAAGTACGTTAAGCTATCATAAACGATCTGTACATTCTACAGAGAGACCACACATGTGTCAATATTGTGGAGAATCGTTTGTCTCCAAAGAAGCGCATCTTATACACGAAAGGATACACACTGGGGAACGTCCTTATGTTTGCAAAGTGTGTAACATGAAGTACAAATGCTCAAGCAATCTCTGTCAACACATGAAGATCCATTCTGGTCTTAAACCTCATAAGTGTTCGTACTGTAACAAGTGTTTTACACGGAAGGGTGCACTAAACGTTCATGAAAGAATTCATACTGGAGAAAAACCATTCTCCTGTGATACATGTGGCAGGACATTTACACAAAAAAATGACATGCTGAAACACACCAAAACGCATCAGACTAAATCGCTGCATTGTGAACAATGCGATGAAACATTCACAAGAAAGAAAGATATCTTGAAACATATTACATTGCATGAACATAATGATCCTATAATTCAAGAGTACATAGAAATTGAGCAGCAAGTGGAAACTTACAATATGGATATACCTTGTTctcaatttgaataa
Protein Sequence
MTIVCAVKNCKYSSGNEESGHIMFINFPNDDTSKVWAQQCGRTDLLMKSNEELHLNYYICSHHIEDHYFISKLDPVVIDQHAIPTLFKSDIKKKSSKDVFDENEQIEVTESVVLSYCDMNIEVDQYHDIGIRLSNVCRICGESCENGIEIFTGKGSELKLKEKINLHLPITVDMDDLMPQKLCMNCCDKLEVVHSLVISSLKTDMKLKKFLNISNTNYDRRYDEIVKKCSIEINEELHTTQKDTQTTLVELPPNNIEDTSMNQEITRKLNHLEQISTVNNIENEMQSELNNFICTPRKTNKEDESENQNTQHYQENDETVFNKISCFYCRSSFESQEIFENHKILCYNKEITAQKREIVNNNINRRDTNNMEIVDVQYSRDSNTHKNFENEQNLDEHKLSYCTLFDEESYKLSIKSHTNEEQCRTIKELHNINDLAVSEINKKCGHCDTVYGTKKELSNHIAECHKGQLLLKCTVCDKSYEKWSSLDVHEATHRIDKPYLCDLCGKSFKHSNNLRGHKRTHLDDSKKKRHICEICGHAFRSRFHLAEHMNQHNGNKPYACDKCGKAFYKRIQLRQHTLSHGLNKHICPICGVAFNRKGNMNAHLKRHNNGSGVYTCSVCAHRCNSMSELKLHRKKHTEQDIIDSIQKKCIDKAALQCKICNRIFSTRTVLLNHERTHRREKLMIECNICGKKLSSRSTLSYHKRSVHSTERPHMCQYCGESFVSKEAHLIHERIHTGERPYVCKVCNMKYKCSSNLCQHMKIHSGLKPHKCSYCNKCFTRKGALNVHERIHTGEKPFSCDTCGRTFTQKNDMLKHTKTHQTKSLHCEQCDETFTRKKDILKHITLHEHNDPIIQEYIEIEQQVETYNMDIPCSQFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00963987;
90% Identity
iTF_00963987; iTF_00963345; iTF_00964626; iTF_00961979;
80% Identity
-