Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:949747-961765[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 30 4.5e-06 0.00028 20.4 1.0 1 23 218 240 218 240 0.98

2 30 0.0066 0.41 10.4 3.7 1 23 263 286 263 286 0.96

3 30 9.8e-05 0.006 16.2 0.5 2 23 293 315 292 315 0.96

4 30 0.00077 0.047 13.4 0.6 2 21 337 356 336 357 0.92

5 30 0.019 1.2 9.0 0.0 2 23 451 472 450 472 0.94

6 30 0.0038 0.24 11.2 0.4 2 23 479 501 478 501 0.91

7 30 8.6e-05 0.0053 16.4 0.1 1 23 568 591 568 591 0.96

8 30 0.017 1.1 9.1 0.4 1 23 597 620 597 620 0.96

9 30 0.045 2.8 7.8 0.8 1 23 633 655 633 655 0.97

10 30 3.4e-05 0.0021 17.6 0.9 3 23 699 720 698 720 0.96

11 30 0.00095 0.059 13.1 1.0 2 23 780 803 779 803 0.95

12 30 2.3 1.4e+02 2.4 0.0 2 23 812 834 812 834 0.84

13 30 0.063 3.9 7.3 0.1 2 23 841 863 840 863 0.95

14 30 9.5e-06 0.00058 19.4 1.2 1 23 871 893 871 893 0.98

15 30 0.52 32 4.4 0.8 3 23 921 943 919 943 0.83

16 30 0.00015 0.0094 15.6 3.3 1 23 946 969 946 969 0.97

17 30 0.0003 0.019 14.6 0.3 2 23 976 998 975 998 0.96

18 30 0.00061 0.038 13.7 5.0 1 21 1022 1042 1022 1043 0.95

19 30 0.002 0.12 12.1 1.8 2 23 1057 1078 1056 1079 0.93

20 30 0.32 20 5.1 1.4 1 23 1082 1105 1082 1105 0.94

21 30 0.019 1.2 9.0 1.0 2 23 1112 1135 1111 1135 0.92

22 30 2.2 1.4e+02 2.5 0.2 2 23 1143 1165 1143 1165 0.94

23 30 6.8 4.2e+02 0.9 0.0 2 23 1172 1194 1171 1194 0.88

24 30 0.16 10 6.0 2.7 2 23 1203 1225 1203 1225 0.96

25 30 2.3 1.4e+02 2.4 0.1 2 23 1231 1253 1231 1253 0.94

26 30 7.2e-05 0.0044 16.6 0.2 1 23 1315 1338 1315 1338 0.96

27 30 0.031 1.9 8.3 3.0 1 20 1363 1382 1363 1384 0.94

28 30 0.23 14 5.5 1.9 2 23 1488 1510 1487 1510 0.94

29 30 0.061 3.7 7.4 0.9 2 23 1517 1539 1516 1539 0.94

30 30 3.5 2.1e+02 1.9 2.6 1 23 1550 1572 1550 1572 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	30	4.5e-06	0.00028	20.4	1.0	1	23	218	240	218	240	0.98
2	30	0.0066	0.41	10.4	3.7	1	23	263	286	263	286	0.96
3	30	9.8e-05	0.006	16.2	0.5	2	23	293	315	292	315	0.96
4	30	0.00077	0.047	13.4	0.6	2	21	337	356	336	357	0.92
5	30	0.019	1.2	9.0	0.0	2	23	451	472	450	472	0.94
6	30	0.0038	0.24	11.2	0.4	2	23	479	501	478	501	0.91
7	30	8.6e-05	0.0053	16.4	0.1	1	23	568	591	568	591	0.96
8	30	0.017	1.1	9.1	0.4	1	23	597	620	597	620	0.96
9	30	0.045	2.8	7.8	0.8	1	23	633	655	633	655	0.97
10	30	3.4e-05	0.0021	17.6	0.9	3	23	699	720	698	720	0.96
11	30	0.00095	0.059	13.1	1.0	2	23	780	803	779	803	0.95
12	30	2.3	1.4e+02	2.4	0.0	2	23	812	834	812	834	0.84
13	30	0.063	3.9	7.3	0.1	2	23	841	863	840	863	0.95
14	30	9.5e-06	0.00058	19.4	1.2	1	23	871	893	871	893	0.98
15	30	0.52	32	4.4	0.8	3	23	921	943	919	943	0.83
16	30	0.00015	0.0094	15.6	3.3	1	23	946	969	946	969	0.97
17	30	0.0003	0.019	14.6	0.3	2	23	976	998	975	998	0.96
18	30	0.00061	0.038	13.7	5.0	1	21	1022	1042	1022	1043	0.95
19	30	0.002	0.12	12.1	1.8	2	23	1057	1078	1056	1079	0.93
20	30	0.32	20	5.1	1.4	1	23	1082	1105	1082	1105	0.94
21	30	0.019	1.2	9.0	1.0	2	23	1112	1135	1111	1135	0.92
22	30	2.2	1.4e+02	2.5	0.2	2	23	1143	1165	1143	1165	0.94
23	30	6.8	4.2e+02	0.9	0.0	2	23	1172	1194	1171	1194	0.88
24	30	0.16	10	6.0	2.7	2	23	1203	1225	1203	1225	0.96
25	30	2.3	1.4e+02	2.4	0.1	2	23	1231	1253	1231	1253	0.94
26	30	7.2e-05	0.0044	16.6	0.2	1	23	1315	1338	1315	1338	0.96
27	30	0.031	1.9	8.3	3.0	1	20	1363	1382	1363	1384	0.94
28	30	0.23	14	5.5	1.9	2	23	1488	1510	1487	1510	0.94
29	30	0.061	3.7	7.4	0.9	2	23	1517	1539	1516	1539	0.94
30	30	3.5	2.1e+02	1.9	2.6	1	23	1550	1572	1550	1572	0.92

Sequence Information

Coding Sequence: ATGGAGCCCAGGGAACGCTACCAAGAGCTTTGCAGACTTTGCGCATCCTACGACGCCGTCAAGATGGACATCTTCGGTCAAGAGGGCAAGAACAGACAGCTAGTTGACAAGATACAAGCTTGTCTACCGTTTAAGATTGCTGAAAATGATCGATTGCCAAAATGCCTGTGTTACCGGTGTATgtacaatttggaaaatttctacGACTTCAGAACAGCGTGTGTCAATGCAGTTGCTCTCTTGGAAAGATGTTTACCACCTTCGGAAtcgaATGGAAATATTACAACCACCTTAACATGTAACGATTTACAGGTGTACAAAGGAAAAGAAAGTTTACCAATTTTGATTCCAGAAGCTCCTATTGTAAATCCAAATGCTGCCTTAGGCACACCACCTAGATTAAATTCTGATGGAGAGGCTGATCATGAGACAGAAGAAATTGTTGATAATAGTGCCACAGATGAAgCAACAATGGTAGATGATGAGTTTGAGGATCATCGTTCAGAGGAATATGAAATGGATATGGAAACAAATCCGAGCGATTTTTTAGAAATGACTTCAATGGTTACAGAAGAACCTGAAGAATCTGTTATAAGATATCAGGAACTTCCTAATAATTTACCAGAGCACACGTCTCAGCAACATGAAGTTTACGTTTGTTCCTTATGTAACAAGGCATTTAGTTCGAAAGGTCATTTATCGTTACATGCACGCATTCATGTAGGCGCCGGCGATGTTATTGGCGAAAAAGTGCTTACAGATGATCATACATCGTATAAAAGACCCTACCAGTGTGATCTTTGTCATAAATCATATTCAACTGCTAAACATCGTTGGGGTCATGTTTCTACAACTCATAGAGGTCACCCAGCAGTGACATGTGGTTATTGTTCACGGATCTACTCAACTCGAACAAATTTAGAAGAACATATAAAATCACGTCACGCTGGTCTTCTAGCACCCACGGGGGTTCCAGTCAGCAATTCCTATCGTCCAGAAAATAGATGTCAGTGCAATGTTTGCGGGAAAGTATGTACAGATGCCATGGAATTGAATCTCCATGGTAGAATTTGCACTGAAGTACAAAACTTGCCGGCAAGAAATGAAAGTAGtgagaataaaattgttgataGTTCTGAAACATCGAGTGTTGCTAGTGATGATGATAGCAAAGATTATAGAACTGCAGAAGCTAAGTTAGCTAACAATCCTcagttaacaattttaaaacaggcATTAACGAAAGGAGATAGTCTTAAACGAGACTTTGAAGACAAGTTCACAACAAATTGTAAACCGAAAAAATTACCGAAGACAGATAACACAGATacgcaaaataataaaaaatggtatTGTGAATTTTGTCCTCAGTCTTTCGCTTCAGTTGAGGATTTCAAAGAGCATGAAGCAATTCATGATGCTAATAAGCCTTTTATCTGTATTCTTTGTAACAAAGATTTTGTTCTTAAGTCTTCCTTAAGCAAGCACATTCAGATGTTACATGGTGTTGATCCATGTCCTATAATTGAAAGTGATAAGTGTTTAAAAAAGGTGGTTTCCCAGAATTGGAACGAGTCTATAGATCTTGATATATACGAGGGTAAAGCTTCCGAATTTCCTTTGTCATCAGAGgcaaatatagaaaatgaGGAAGAAGATCGGGAAAGTGGACAGGAGAACCTAATCGAAATTGAAACCGTATTTGTTTGTGAAATCTGTACTCGAGATTTTAATGATCGCGCATCTCTTTGGCTTCATATCCGAGCTACTCATAAAGAATTCGCAGCATTTGCGTGCGGTGtttgtctaaaaatttgtgcaGACAATACACAACTTCTAAATcatgtaaatatgtatcatGGCGGTTCGAAGTTATTATTATCTGAACAAAGaagATACAGTTGTACTATCTGTGGCAGGCAGCATGATTCcaggaaaaaattaattgcacaTGTATCTATACATAATGTTGATCCAAACTTCGATCCTGCAAATTTTGTACAGTTAAATAGCAATTACTATGGAGAAAATATTAATGGCAACGAAACAACAGAACAAATGCTTGATTATGAAGAAGACGGAGACAAAGTGGActgttatatttgttataaatcgTTTCCTAGTGAAGATCATTTAATACGACATCAAAGAAACGCACATAGgtcTGAACAGCTAGTGCCAACAGGAGATACTTTAAATTCGTCGAGTTTAAATGGGGGTGGAAATAGAGCTCAGTACCATCTCTTCTTTGTTTGTGAACTTTGTGGTAGTTCACATCCTAGCAAATGGGAACGTTGGTTGCACGTCAGTTCTTCTCATAGTAATGAATCAGCTATAAAATGTGATCGTGAAGATTGTGGTAAAATCTTCGCGACGAAATCTCTAAGAAACGATCACATCCAACATCATGTGATTCAAGGTTCTTCTCCCAACACGTGTGAAATTTGTGGTAAACTTTGGGGCAGTAGAGTTGATTACTGGAAACATGTTATGGGCGTTCACTCGGATACCGTTCCATTAATTTGTGGAGTCTGTTTAAAAGTGTTCCCAAATGTTTTACAACTGAGTACTCATGTGAAATCGAAACATTGGCCATTAACAAACGGCGACTTTAGTTGTGACATTTGTGGAAGGCCATATTCGAATAAATCCAAAATGTCCAGGCACAGAAAAATTCACGGATTTGAAGAGATTTGTGATAATGTAGCCgagaataatgaaaataaaatagatggACAAATCAGGGAAAGTGAATTAAGTTGTGAACTTTGTGCAGActtaaaattctctaatttagaaaaattgtgtaatcATAGGCGAATTGTTCATGGACTTTTCCCTTGTGATCTCTGCAACAAATGTTATGGAAGAACTTCCCACTTATGGAAACATGTGAATAGAGTTCACAAAGGTCACGAAGACGTAACCTGTCCTTATTGTTTGAAAACCAGTGCTTCCAAAGATCATTTGGCTGCACATATATCCAAAATTCATAGATACGAACCTGACTCTAGAAAAGACAGAAAAGACAGTAGACAATTTAAAACTGAAGAAGTTAGTTTACATTATTGtgagaaatgtaataaaagatTTCATAAACGGTATCTGCTGCGCAGACATATGAAAGGGTGTCAGAATTACAGAAAAGATCCTGGGGCACTTTTAACAAGATGCAGAGCTTGCGAACGAATATTTAAGGATCGTGCTAGTCTACAAAAGCATATTGAGAATCATCATAGTACATACACTTGTCATCTTTGCAACGAGACGATCACTTCAAAATTAGGAATTATGACGCATAATAGAGTGAAACATATGGATCATCCAGatttaacttgtaattttGGTTCCTGCaggaaattatttagaacTAAAGAAGATTTAGAAGCTCATAAGAAAGATCATAGgTATCATACAACGCCGAATGTGTGTGATTTCTGCGGTGACACAGTAGAGAATAAACTCAAGTTAAAAATGCATGTACTGTCACTTCATCGCAATGAAATTGGTGTGTCCTGCGGAGTTTGTTTAATTCCAATGAAGGATCCAAAGGAGCTTAAGAGTCATGTAGAAGAAGTTCATTCCAGTGTTCTTTCGAGACCCAATACCTGTCAAGTCTGTGGAAAGCAGTATGCGTCAAAGTGGAAGGCTTTTGATCATACTAAAAAGTGTCATGGAAAAGTGTTTAGGACTTGTAAGCAGTGTTTAGCTGTTTTCACTGAAGATTCCGCGATCAGAGATCATTATGAAAGAGTGCATAACATTTCGAAAGACCAATTTGCTGCATTTGAATATAGGTTGGATATCGGTtcgaaaaatgaatttgagtTAGAATCTGCCGATGTAGTAGTTAAAGATGAGCCAGATGATTTGGAGTATGATGTAGATCTTTGTGATGAGGATTCTAATGACTCAAAAAGAAGAAGATCTTTAACAGACACATTCGATTGTGAAATGTGTCCTGAGATGTTCGTGAGCAGCGATGCTCTTTCAAAACATTATCGTAATATGCACAATACAGATCCAGAAAGAAtgtttaaaagattaaaacaAGACGAACAGCGAAGAATGCGCGGAAGAATGAATTTCtcttgtaaaaattgcaagagaCAATTTTGCACAAAAACATTGTATTGGAGTCACGTTGCAAATTGTAGAAGAAGTGCTTTACGAAAAGAAGAGGAATTATTACCCTTGCgtaataatatgttaaatgtTCGAGAAAACATACTTGGAAGCGGGGAAGAGATTTTGAAGAATaatcatcaaattaaaaaagaagagcCTACaacgaatttaaatatacCTGACTTCAATCTTTTTGAGGATATAAATCTTCAGTTATCGGGCCAAAGACCTCTTCCAAATCTAATGCCACTGCCTCAGagAACAAAAACCACAATGAAATGTTCAAGAAAGGATTCCAGAAAGGTTTATGACGAATCAACGAATACAGAATGTACTTGTGAAGTTTGTGGAAAACAGTGGCCAGCAAAGAAACATTTATGGCAACACTTAATTCGTTTCCATCGAGCAGAAGCTGCTGTTACTTGCGGAGTGTGTTTGAAGCTCTGTAAAGATTATGATGATTTAACAAATCATTTAAAAGCTACACACGAAGCAATTCTATCATGTGAAGGAAATAACTTCACGTGTAAAACTTGTGGCAGGTATCACAACGCTCGTAGTAAATTGTTATTGCACACAAGCATTCATCTTGGACATTCGAGCAACAGTACTTGGTGTTCAAAATGTAGGAAGAATGTAACGGACGAAGCTGCTCATTCAAATATCTGTTCAGGAAaggtagaagaagaagaacaacAGCAATTAAAGAATGATGAAAAGGCGGAaGGAAGCCTAATAGCAGATGATGCTATGATTGAGGTAGAAGAAGGGGATTATGAATCTGAAGCCGAAGAAGTGGATACGGAAGAATCAGACAGTGGTAGTAGTACCGAagttgaagaagaaaatgaatcAGAGGGTGAATCGAGAGTCACTGGAGAAATTACTTATAACTCAGAAAGCGAAGATTCTGAAGAACTAGATAATTTAGACATCGAGGAAAAGAATATGCAACGTTATACTTTGGAACGTCTTCAGGAAAACGAGAATACAGaAACACGGAAGAACGTAGATTTGTCAGATGATGATGGACCTCCTGTTCTTAGTCCCATGATGCCTTTGCTTCGAGAAAATATCTCCGAAGATCAATCAATGGGCCACAAATTTGGTTCTGTAATACCTCTAACAGAGAAGGAAATAAAAGCATGTGATTTGTCAGAAATTCGAAATCGATCTCCGAAGTCACTAAATTTGTACGAAAAAGACTTACCTAATAATTCAACTTTAGACTTTGTGTCTAAAACATTTATGAATCGAAGTGATGAAGATTTTCAAAATGCGAAAGTTGAATTTGATGAGAATTCTGTTGAAGAAAATGACGAAGAGAATGATGAACACGAAGAAAATGACGAGGATAACGACGAAcacgaagaaaatgaagaaaatgacGAACATGatgaaaacgaagaaaatgagGAGAACGAAGAAAACGATGAAATTGAAGATAGCAgggaaaatgaagaatatgAAGAAAATGAGGAGTACGATGGAAACGAAGAAATGTACGAAAATGAAGAGAATGATTGCAATGAAGAAGAAAGCGAGGGAAgcgaagaaaatgaagataacGAAGAAGGAAacgaagaaattgaagaacatGACGACGATGAAGAGAACGAAGAAAGGGACGATAATGTGCAGCTGGATGATTTAGAGGGTGCTGTTTTGATGGTGACTGAAGGAGATCAAATACTGATTCAACAAGACATACTGGAAGATGAAAATGAAAACTCGAAACAAGAATATGTTTATTCTACGCTTAGGTATAGTACAGAAGAAGATAGTGACGATGCAAGGAAATGA
Protein Sequence: MEPRERYQELCRLCASYDAVKMDIFGQEGKNRQLVDKIQACLPFKIAENDRLPKCLCYRCMYNLENFYDFRTACVNAVALLERCLPPSESNGNITTTLTCNDLQVYKGKESLPILIPEAPIVNPNAALGTPPRLNSDGEADHETEEIVDNSATDEATMVDDEFEDHRSEEYEMDMETNPSDFLEMTSMVTEEPEESVIRYQELPNNLPEHTSQQHEVYVCSLCNKAFSSKGHLSLHARIHVGAGDVIGEKVLTDDHTSYKRPYQCDLCHKSYSTAKHRWGHVSTTHRGHPAVTCGYCSRIYSTRTNLEEHIKSRHAGLLAPTGVPVSNSYRPENRCQCNVCGKVCTDAMELNLHGRICTEVQNLPARNESSENKIVDSSETSSVASDDDSKDYRTAEAKLANNPQLTILKQALTKGDSLKRDFEDKFTTNCKPKKLPKTDNTDTQNNKKWYCEFCPQSFASVEDFKEHEAIHDANKPFICILCNKDFVLKSSLSKHIQMLHGVDPCPIIESDKCLKKVVSQNWNESIDLDIYEGKASEFPLSSEANIENEEEDRESGQENLIEIETVFVCEICTRDFNDRASLWLHIRATHKEFAAFACGVCLKICADNTQLLNHVNMYHGGSKLLLSEQRRYSCTICGRQHDSRKKLIAHVSIHNVDPNFDPANFVQLNSNYYGENINGNETTEQMLDYEEDGDKVDCYICYKSFPSEDHLIRHQRNAHRSEQLVPTGDTLNSSSLNGGGNRAQYHLFFVCELCGSSHPSKWERWLHVSSSHSNESAIKCDREDCGKIFATKSLRNDHIQHHVIQGSSPNTCEICGKLWGSRVDYWKHVMGVHSDTVPLICGVCLKVFPNVLQLSTHVKSKHWPLTNGDFSCDICGRPYSNKSKMSRHRKIHGFEEICDNVAENNENKIDGQIRESELSCELCADLKFSNLEKLCNHRRIVHGLFPCDLCNKCYGRTSHLWKHVNRVHKGHEDVTCPYCLKTSASKDHLAAHISKIHRYEPDSRKDRKDSRQFKTEEVSLHYCEKCNKRFHKRYLLRRHMKGCQNYRKDPGALLTRCRACERIFKDRASLQKHIENHHSTYTCHLCNETITSKLGIMTHNRVKHMDHPDLTCNFGSCRKLFRTKEDLEAHKKDHRYHTTPNVCDFCGDTVENKLKLKMHVLSLHRNEIGVSCGVCLIPMKDPKELKSHVEEVHSSVLSRPNTCQVCGKQYASKWKAFDHTKKCHGKVFRTCKQCLAVFTEDSAIRDHYERVHNISKDQFAAFEYRLDIGSKNEFELESADVVVKDEPDDLEYDVDLCDEDSNDSKRRRSLTDTFDCEMCPEMFVSSDALSKHYRNMHNTDPERMFKRLKQDEQRRMRGRMNFSCKNCKRQFCTKTLYWSHVANCRRSALRKEEELLPLRNNMLNVRENILGSGEEILKNNHQIKKEEPTTNLNIPDFNLFEDINLQLSGQRPLPNLMPLPQRTKTTMKCSRKDSRKVYDESTNTECTCEVCGKQWPAKKHLWQHLIRFHRAEAAVTCGVCLKLCKDYDDLTNHLKATHEAILSCEGNNFTCKTCGRYHNARSKLLLHTSIHLGHSSNSTWCSKCRKNVTDEAAHSNICSGKVEEEEQQQLKNDEKAEGSLIADDAMIEVEEGDYESEAEEVDTEESDSGSSTEVEEENESEGESRVTGEITYNSESEDSEELDNLDIEEKNMQRYTLERLQENENTETRKNVDLSDDDGPPVLSPMMPLLRENISEDQSMGHKFGSVIPLTEKEIKACDLSEIRNRSPKSLNLYEKDLPNNSTLDFVSKTFMNRSDEDFQNAKVEFDENSVEENDEENDEHEENDEDNDEHEENEENDEHDENEENEENEENDEIEDSRENEEYEENEEYDGNEEMYENEENDCNEEESEGSEENEDNEEGNEEIEEHDDDEENEERDDNVQLDDLEGAVLMVTEGDQILIQQDILEDENENSKQEYVYSTLRYSTEEDSDDARK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00218574;
90% Identity: iTF_00962658;
80% Identity: -